iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048014

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01072719

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000011495.2	ENSSTOT00000011494.2	ENSSTOP00000010315.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-19	69.2	78	111
UBD/Beta-Prp	5.50e-41	140.7	149	287

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v+c++  ++++vsGs+D t kvW l +g+l
   Q: 78   HEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL 111
           99*******9449***************999875 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.sDg 244
           +r+Wdl++g+l+++l ++  +    l++ +++   l+s+++d++v++wdl+    +cv+++++ h+++ ++++++  +++l++gs   g
   Q: 149  LRIWDLNSGQLMTHLGSDFPPGAGVLDVMYESpSTLLSCGYDTYVRYWDLRtsVRKCVMEWEEpHDSTLYCLQTD-GNHLLATGSsYYG 236
           79*************99999999****99999789****************88789*****9999**********.999999999789* PP
   S: 245  siriWdlrsgdllktlqlhn.ssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++r+Wd r++ +l+++ l+    +++v +l+f+ ++l+++ +  ++++++++
   Q: 237  VVRLWDRRQRACLHAFPLTStPLSSPVYCLRFTTKHLYAALS-YNLHVLDFQ 287
           ******************99667889***********99866.467777765 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MQLEDDSLYI SQANFILAYK FRPDGASLNR RPLGVFAGHD EDVCHFVLAN SHIISAGGDG 60
KIGVHKIHST FTVKYSAHEQ EVNCVDCKGG IIVSGSRDRT AKVWPLASGR LGQCLHTIQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGACAGG AGCGGCCATG GCGGCGGCAG CCGAGGAGGA AGCGGCGGCT CGGGAGCCCG 60
CTGCTCGGCC GGCTGCAGGG CCCGCGCTCT GGCGCCTGCC CGAGGAGCTG CTGCTGCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	98.27	2.00e-171	594.00
IUUC-Apl-003837	Anas platyrhynchos	72.66	8.00e-128	449.00
IUUC-Aca-004776	Anolis carolinensis	69.23	2.00e-106	379.00
IUUC-Ame-010651	Astyanax mexicanus	62.98	2.00e-100	358.00
IUUC-Bta-013495	Bos taurus	97.23	1.00e-160	558.00
IUUC-Cja-018901	Callithrix jacchus	98.62	8.00e-163	566.00
IUUC-Cfa-021251	Canis familiaris	97.58	1.00e-169	588.00
IUUC-Cpo-021750	Cavia porcellus	94.46	6.00e-166	576.00
IUUC-Csa-024026	Chlorocebus sabaeus	98.62	5.00e-172	597.00
IUUC-Cho-024496	Choloepus hoffmanni	70.93	3.00e-113	401.00
IUUC-Cin-025142	Ciona intestinalis	29.68	5.00e-12	64.30
IUUC-Csv-025883	Ciona savignyi	38.00	1.00e-54	206.00
IUUC-Dre-027447	Danio rerio	62.15	6.00e-102	363.00
IUUC-Dno-029572	Dasypus novemcinctus	87.03	2.00e-145	508.00
IUUC-Dor-030982	Dipodomys ordii	98.62	1.00e-171	595.00
IUUC-Dme-031804	Drosophila melanogaster	22.71	3.00e-10	59.30
IUUC-Ete-032917	Echinops telfairi	97.92	1.00e-170	591.00
IUUC-Eca-033969	Equus caballus	98.62	2.00e-162	564.00
IUUC-Eeu-034850	Erinaceus europaeus	85.12	1.00e-144	505.00
IUUC-Fca-036182	Felis catus	98.27	5.00e-171	593.00
IUUC-Fal-037391	Ficedula albicollis	72.03	4.00e-122	430.00
IUUC-Gmo-038632	Gadus morhua	59.17	5.00e-99	354.00
IUUC-Gga-040783	Gallus gallus	73.43	3.00e-127	448.00
IUUC-Gac-042314	Gasterosteus aculeatus	59.86	2.00e-87	315.00
IUUC-Ggo-044739	Gorilla gorilla	98.62	1.00e-171	595.00
IUUC-Hsa-046705	Homo sapiens	98.27	1.00e-162	565.00
IUUC-Loc-052397	Lepisosteus oculatus	69.55	6.00e-115	406.00
IUUC-Laf-054544	Loxodonta africana	97.59	1.00e-169	588.00
IUUC-Meu-056363	Macropus eugenii	64.62	3.00e-91	327.00
IUUC-Mga-059275	Meleagris gallopavo	73.43	2.00e-127	448.00
IUUC-Mmr-060906	Microcebus murinus	98.62	3.00e-171	594.00
IUUC-Mdo-062400	Monodelphis domestica	77.51	4.00e-137	480.00
IUUC-Mmu-063556	Mus musculus	95.16	8.00e-167	579.00
IUUC-Mpu-066500	Mustela putorius furo	97.92	8.00e-171	592.00
IUUC-Mlu-068074	Myotis lucifugus	97.58	2.00e-169	587.00
IUUC-Nle-069601	Nomascus leucogenys	98.62	1.00e-171	595.00
IUUC-Opr-070904	Ochotona princeps	85.64	2.00e-100	358.00
IUUC-Ont-072679	Oreochromis niloticus	58.68	7.00e-99	353.00
IUUC-Oan-073434	Ornithorhynchus anatinus	75.19	4.00e-58	217.00
IUUC-Ocu-074649	Oryctolagus cuniculus	97.58	1.00e-170	592.00
IUUC-Ola-087336	Oryzias latipes	50.53	1.00e-81	296.00
IUUC-Oga-088590	Otolemur garnettii	95.85	1.00e-158	551.00
IUUC-Oar-090178	Ovis aries	97.23	3.00e-160	557.00
IUUC-Pan-092881	Papio anubis	98.96	7.00e-172	596.00
IUUC-Pfo-096176	Poecilia formosa	58.95	2.00e-92	332.00
IUUC-Pab-098285	Pongo abelii	98.62	8.00e-172	596.00
IUUC-Pca-100888	Procavia capensis	91.35	3.00e-153	534.00
IUUC-Pva-102184	Pteropus vampyrus	80.28	1.00e-133	469.00
IUUC-Rno-105668	Rattus norvegicus	95.16	7.00e-167	579.00
IUUC-Sha-106629	Sarcophilus harrisii	77.51	5.00e-138	483.00
IUUC-Ssc-116183	Sus scrofa	99.31	1.00e-172	599.00
IUUC-Tgu-116630	Taeniopygia guttata	72.03	1.00e-125	442.00
IUUC-Tru-118761	Takifugu rubripes	55.79	6.00e-96	343.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.97	2.00e-60	224.00
IUUC-Ttr-128582	Tursiops truncatus	96.89	3.00e-159	554.00
IUUC-Vpa-130431	Vicugna pacos	76.62	1.00e-98	352.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence