iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097960

Ensembl Protein ID

ENSPPYP00000013486.2

UniProt Accession

H2P576; H2P576_PONAB

Genbank Protein ID

ENSPPYP00000013486

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

ABGA01021156

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012095.2	ENSPPYT00000014035.2	ENSPPYP00000013486.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	1.40e-22	78.6	1012	1040

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1012 AFSQVDPEVFAALPAELQRELKAAYDQRQ 1040
           59*************************98 PP

Organism

Pongo abelii

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRKRA ENDGWETWGG YMAAKVQKLE EQFRSDAAMQ KDGTSSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCTGCGG CGCGCGCGCT AACCGGAGGG GGAGGGGCGG AGAGCTACCG CGGAGCGCGC 60
GCGGGGTTGG TTGCCGCGAG CGTGGATCGC GGCGCTGCTC GGCGGTGGGG CTGACTTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	30.14	1.00e-30	128.00
IUUC-Aml-001185	Ailuropoda melanoleuca	88.36	0.00e+00	2163.00
IUUC-Atr-002915	Amborella trichopoda	30.03	2.00e-109	390.00
IUUC-Apl-004054	Anas platyrhynchos	76.03	0.00e+00	1802.00
IUUC-Aca-004304	Anolis carolinensis	68.78	0.00e+00	1644.00
IUUC-Aly-005696	Arabidopsis lyrata	36.42	7.00e-86	312.00
IUUC-Ath-006893	Arabidopsis thaliana	36.31	1.00e-86	314.00
IUUC-Ago-007722	Ashbya gossypii	27.92	3.00e-39	157.00
IUUC-Acl-008347	Aspergillus clavatus	34.44	3.00e-89	323.00
IUUC-Afl-008444	Aspergillus flavus	35.73	6.00e-89	322.00
IUUC-Afu-008837	Aspergillus fumigatus	30.92	4.00e-87	316.00
IUUC-Ani-009188	Aspergillus nidulans	38.91	1.00e-93	337.00
IUUC-Ang-009866	Aspergillus niger	33.62	6.00e-99	355.00
IUUC-Aor-010107	Aspergillus oryzae	35.73	8.00e-89	322.00
IUUC-Ate-010359	Aspergillus terreus	31.77	2.00e-92	334.00
IUUC-Ame-010664	Astyanax mexicanus	49.19	0.00e+00	1095.00
IUUC-Bgr-012244	Blumeria graminis	31.85	2.00e-84	307.00
IUUC-Bta-013405	Bos taurus	80.07	0.00e+00	1812.00
IUUC-Bci-013849	Botrytis cinerea	31.08	5.00e-87	316.00
IUUC-Bdi-014066	Brachypodium distachyon	36.73	3.00e-85	310.00
IUUC-Bol-015544	Brassica oleracea	37.08	1.00e-88	321.00
IUUC-Bra-017792	Brassica rapa	35.21	1.00e-84	308.00
IUUC-Cel-018148	Caenorhabditis elegans	36.16	2.00e-82	300.00
IUUC-Cja-019742	Callithrix jacchus	81.57	0.00e+00	1620.00
IUUC-Cfa-020112	Canis familiaris	88.92	0.00e+00	2198.00
IUUC-Cpo-022152	Cavia porcellus	84.44	0.00e+00	2130.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	42.56	4.00e-40	159.00
IUUC-Csa-023504	Chlorocebus sabaeus	96.32	0.00e+00	2391.00
IUUC-Cho-024780	Choloepus hoffmanni	65.41	0.00e+00	719.00
IUUC-Cin-025276	Ciona intestinalis	42.89	6.00e-112	398.00
IUUC-Csv-026283	Ciona savignyi	44.79	3.00e-116	412.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	28.26	2.00e-90	327.00
IUUC-Cne-027079	Cryptococcus neoformans	33.93	3.00e-78	286.00
IUUC-Cme-027346	Cyanidioschyzon merolae	28.95	4.00e-48	186.00
IUUC-Dre-028073	Danio rerio	50.41	0.00e+00	1097.00
IUUC-Dno-030038	Dasypus novemcinctus	81.75	0.00e+00	2019.00
IUUC-Dor-031100	Dipodomys ordii	84.16	0.00e+00	1529.00
IUUC-Dse-031310	Dothistroma septosporum	29.62	8.00e-86	312.00
IUUC-Dme-031991	Drosophila melanogaster	43.15	4.00e-112	399.00
IUUC-Ete-033082	Echinops telfairi	77.13	0.00e+00	1431.00
IUUC-Eca-033471	Equus caballus	87.72	0.00e+00	2162.00
IUUC-Eeu-034993	Erinaceus europaeus	84.63	0.00e+00	1412.00
IUUC-Fca-035367	Felis catus	88.38	0.00e+00	2103.00
IUUC-Fal-036973	Ficedula albicollis	75.45	0.00e+00	1744.00
IUUC-Fox-037677	Fusarium oxysporum	30.88	6.00e-87	315.00
IUUC-Fso-038252	Fusarium solani	31.02	5.00e-89	322.00
IUUC-Gmo-039669	Gadus morhua	52.39	0.00e+00	818.00
IUUC-Ggr-039988	Gaeumannomyces graminis	35.26	9.00e-86	311.00
IUUC-Gga-040423	Gallus gallus	75.87	0.00e+00	1795.00
IUUC-Gac-042134	Gasterosteus aculeatus	47.91	0.00e+00	975.00
IUUC-Gma-042929	Glycine max	37.24	1.00e-89	324.00
IUUC-Ggo-044528	Gorilla gorilla	98.72	0.00e+00	2426.00
IUUC-Hsa-046259	Homo sapiens	98.64	0.00e+00	2394.00
IUUC-Hvu-047139	Hordeum vulgare	37.43	8.00e-60	224.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	88.52	0.00e+00	2185.00
IUUC-Kpa-049169	Komagataella pastoris	29.27	4.00e-62	233.00
IUUC-Lch-050471	Latimeria chalumnae	65.70	0.00e+00	1546.00
IUUC-Lpe-050800	Leersia perrieri	33.54	5.00e-89	322.00
IUUC-Loc-052320	Lepisosteus oculatus	47.12	0.00e+00	938.00
IUUC-Lma-053149	Leptosphaeria maculans	28.72	2.00e-85	310.00
IUUC-Laf-053810	Loxodonta africana	82.38	0.00e+00	1964.00
IUUC-Mcc-055574	Macaca mulatta	97.60	0.00e+00	2359.00
IUUC-Meu-055945	Macropus eugenii	65.71	0.00e+00	1146.00
IUUC-Mor-057195	Magnaporthe oryzae	29.86	6.00e-91	329.00
IUUC-Mpo-057488	Magnaporthe poae	34.66	5.00e-86	312.00
IUUC-Mtr-057955	Medicago truncatula	36.95	5.00e-90	326.00
IUUC-Mla-059027	Melampsora laricipopulina	35.84	4.00e-80	292.00
IUUC-Mga-060156	Meleagris gallopavo	75.47	0.00e+00	1790.00
IUUC-Mvi-060398	Microbotryum violaceum	36.21	9.00e-83	302.00
IUUC-Mmr-061113	Microcebus murinus	91.31	0.00e+00	2211.00
IUUC-Mdo-063001	Monodelphis domestica	82.68	0.00e+00	1988.00
IUUC-Mmu-063180	Mus musculus	82.30	0.00e+00	2026.00
IUUC-Mac-065551	Musa acuminata	38.75	2.00e-55	210.00
IUUC-Mpu-066525	Mustela putorius furo	88.68	0.00e+00	2165.00
IUUC-Mlu-067877	Myotis lucifugus	85.89	0.00e+00	2095.00
IUUC-Nfi-068418	Neosartorya fischeri	31.92	2.00e-87	317.00
IUUC-Ncr-068648	Neurospora crassa	32.25	2.00e-88	321.00
IUUC-Nle-069959	Nomascus leucogenys	98.64	0.00e+00	2387.00
IUUC-Opr-070522	Ochotona princeps	83.01	0.00e+00	1193.00
IUUC-Ont-072293	Oreochromis niloticus	49.69	0.00e+00	786.00
IUUC-Oan-073519	Ornithorhynchus anatinus	79.21	0.00e+00	1899.00
IUUC-Ocu-074492	Oryctolagus cuniculus	84.95	0.00e+00	1928.00
IUUC-Oba-075567	Oryza barthii	32.82	3.00e-89	323.00
IUUC-Obr-076332	Oryza brachyantha	36.49	6.00e-87	315.00
IUUC-Ogl-077348	Oryza glaberrima	32.82	4.00e-89	323.00
IUUC-Ogu-078779	Oryza glumaepatula	36.09	9.00e-89	322.00
IUUC-Oin-079738	Oryza indica	32.76	4.00e-77	283.00
IUUC-Olo-080701	Oryza longistaminata	30.21	2.00e-77	284.00
IUUC-Ome-081708	Oryza meridionalis	28.31	8.00e-86	312.00
IUUC-Oni-082251	Oryza nivara	36.09	1.00e-86	315.00
IUUC-Opu-083528	Oryza punctata	35.70	1.00e-80	294.00
IUUC-Oru-084293	Oryza rufipogon	32.04	5.00e-84	306.00
IUUC-Osa-085549	Oryza sativa	36.29	8.00e-89	322.00
IUUC-Ola-086793	Oryzias latipes	46.19	0.00e+00	1003.00
IUUC-Olu-087786	Ostreococcus lucimarinus	28.86	5.00e-60	225.00
IUUC-Oga-089006	Otolemur garnettii	90.23	0.00e+00	2196.00
IUUC-Oar-089597	Ovis aries	81.27	0.00e+00	1972.00
IUUC-Ptr-091520	Pan troglodytes	98.72	0.00e+00	2397.00
IUUC-Pan-092333	Papio anubis	97.36	0.00e+00	2330.00
IUUC-Psi-094004	Pelodiscus sinensis	77.62	0.00e+00	1865.00
IUUC-Pma-094128	Petromyzon marinus	53.55	3.00e-94	338.00
IUUC-Pno-094849	Phaeosphaeria nodorum	28.97	3.00e-80	293.00
IUUC-Ppa-095714	Physcomitrella patens	28.19	5.00e-94	339.00
IUUC-Pfo-096569	Poecilia formosa	47.79	0.00e+00	984.00
IUUC-Pop-098921	Populus trichocarpa	32.67	3.00e-85	310.00
IUUC-Pca-100509	Procavia capensis	68.90	0.00e+00	1197.00
IUUC-Ppe-101730	Prunus persica	33.90	1.00e-118	421.00
IUUC-Pva-102142	Pteropus vampyrus	85.17	0.00e+00	2064.00
IUUC-Pgr-103446	Puccinia graminis	30.90	1.00e-69	258.00
IUUC-Ptt-103849	Puccinia triticina	29.42	1.00e-74	275.00
IUUC-Pte-104128	Pyrenophora teres	30.36	4.00e-83	303.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	31.42	4.00e-81	296.00
IUUC-Rno-104871	Rattus norvegicus	80.14	0.00e+00	1980.00
IUUC-Sce-106236	Saccharomyces cerevisiae	27.77	1.00e-42	168.00
IUUC-Sha-106962	Sarcophilus harrisii	81.80	0.00e+00	1976.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	33.61	2.00e-66	247.00
IUUC-Spo-108170	Schizosaccharomyces pombe	30.49	2.00e-65	244.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	34.79	2.00e-87	317.00
IUUC-Smo-109554	Selaginella moellendorffii	37.08	2.00e-85	311.00
IUUC-Sit-110479	Setaria italica	36.09	2.00e-72	267.00
IUUC-Sly-111752	Solanum lycopersicum	33.66	3.00e-92	333.00
IUUC-Sar-113304	Sorex araneus	85.24	0.00e+00	2031.00
IUUC-Sbi-114196	Sorghum bicolor	36.09	2.00e-72	267.00
IUUC-Sre-115151	Sporisorium reilianum	31.02	3.00e-85	310.00
IUUC-Ssc-116104	Sus scrofa	86.32	0.00e+00	2089.00
IUUC-Tgu-117438	Taeniopygia guttata	75.71	0.00e+00	1767.00
IUUC-Tru-118553	Takifugu rubripes	47.15	0.00e+00	990.00
IUUC-Tsy-119056	Tarsius syrichta	86.23	0.00e+00	2035.00
IUUC-Tni-119933	Tetraodon nigroviridis	47.34	0.00e+00	951.00
IUUC-Tca-121376	Theobroma cacao	33.05	5.00e-114	405.00
IUUC-Tre-121972	Trichoderma reesei	30.45	1.00e-82	301.00
IUUC-Tvi-122342	Trichoderma virens	34.91	8.00e-80	292.00
IUUC-Tae-123898	Triticum aestivum	33.75	2.00e-90	327.00
IUUC-Tur-126735	Triticum urartu	26.56	1.00e-35	145.00
IUUC-Tme-126999	Tuber melanosporum	32.21	1.00e-78	288.00
IUUC-Tbe-127280	Tupaia belangeri	88.57	3.00e-145	509.00
IUUC-Ttr-129104	Tursiops truncatus	85.82	0.00e+00	2080.00
IUUC-Uma-129562	Ustilago maydis	30.92	3.00e-84	307.00
IUUC-Vda-129862	Verticillium dahliae	30.82	4.00e-91	329.00
IUUC-Vpa-130819	Vicugna pacos	82.64	0.00e+00	1086.00
IUUC-Vvi-131111	Vitis vinifera	35.42	4.00e-86	313.00
IUUC-Xtr-132629	Xenopus tropicalis	62.73	0.00e+00	1429.00
IUUC-Xma-134065	Xiphophorus maculatus	51.86	0.00e+00	796.00
IUUC-Yli-134633	Yarrowia lipolytica	32.87	5.00e-63	236.00
IUUC-Zma-135176	Zea mays	36.96	1.00e-87	318.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence