iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026852

Ensembl Protein ID

AAW44768

UniProt Accession

Q5KDK0; Q5KDK0_CRYNJ

Genbank Protein ID

AAW44768.2

Protein Name

Ubiquitin carboxyl-terminal hydrolase 12, putative

Genbank Nucleotide ID

AE017347

Gene Name

CNG03680

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNG03680	AAW44768	AAW44768

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-99	332.1	516	1301

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgyeqqDaqEf 95
           +Gl+NlgNtC+mNS++QcLsn++el +++l+  ++e+ln++np +++g++++++ +++e+lw   +s ++++spr+l+ + +++a++f gy q+D+qEf
   Q: 516  VGLQNLGNTCFMNSAVQCLSNTKELSQYFLSgVYTEELNRDNPLGMQGQIAEAFGQVVENLWaptSSMHSSYSPRQLKWTTSRFAPQFAGYGQHDTQEF 614
           6******************************99*****************************9999999****************************** PP
   S: 96   laflldqleeelkkeknkpkeeeeeedkselsde.......aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.. 185
           +aflld+l+e+l++  +kp+ e+ + +    ++e        ++  kk+n+s+i+dlFqgqlks+++c+ec+++s +++pf++l++p+p  ++++ +  
   Q: 615  IAFLLDGLHEDLNRILKKPYIEKPDWKPGGGDKElaelgkeCWDGYKKRNDSVIVDLFQGQLKSTLVCPECHKESITFDPFMYLTVPLPIAQNRQFKit 713
           **************9*****999998877777778889999************************************************9999988899 PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 714  fvprdtekppvnvkllipqnasfaqvkdkigslfdckgssivgfdlwnnrpyawwadsdhnseakdtdeaifyeldpsvsvsvprgkfgsqprttsqdg 812
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 813  sltvpvytfrtvensrggyragdvpsdlslkpffitltkaeasdpnavreaimrgytrfmkpeakeniyvpassaqakaptppksddgepgteihmsgd 911
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 912  qatvvevpssrqspaigaeepgegapmeldsasastsavtgiqlsgsttsllstnsirssislsgklvpradlfkvyvadptgdfsfksfrsnekkyda 1010
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 1011 ahlydkditsaskswsllesrkkkakkhivnrlasgissmvnpsnnsddevlsdgststspnklekmkekltnsklavrpgegifcewsgadfaewlnd 1109
           *************************************************************************************************** PP
   S: 186  .........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple. 258
                                     ++dcL++f+kee+l +++ +yc+ ckk+q a+kkl++ k P++L++ +kRf   +++ +  k+++ v+fp+  
   Q: 1110 nvkgedvidpaiskelvkkregkhiGIEDCLDEFSKEETLGQDDLWYCPVCKKHQAATKKLEIYKAPDILVICIKRF--GSSRRMGDKLDNLVHFPIDg 1206
           *****************************************************************************..55667999************ PP
   S: 259  Ldlspfcts.....peekqke.................kkkYeLiavvvHsGslssGHYvayvkne.kgkWllfdDskVtevkeeevleetgstaYvlf 334
           Ldl+    +     +                       +  Y+L+av +H G++++GHY+a+++n+ +++W+++dDs+V++ + ++v++   + aY+lf
   Q: 1207 LDLEDRIGErqvakT-----LklngedvegygieddgePLLYDLYAVDNHFGGMGGGHYTAFCRNQvDNQWYNYDDSRVSKADVSSVQS---RAAYLLF 1297
           ****87766333330.....146666666777777777***************************62566*******************...******* PP
   S: 335  Ykrr 338
           Y+rr
   Q: 1298 YRRR 1301
           *996 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MGAGGRVLLV REFSSAALSP AGCRPPTPPR HCLSSFHSIS APSFLLFLYP KSARVPTDIP 60
TKGHFENLFM SSQDLPGTLK RPRSTSRPPS PSSGSSPKRA ASEDPFPSSS DSGRVFDHLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCGCTG GCGGAAGAGT GCTGCTGGTT CGAGAATTTT CTTCCGCTGC TCTCTCACCT 60
GCTGGCTGCC GTCCCCCCAC CCCGCCGCGT CATTGCTTAT CCTCTTTCCA CTCCATCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cne:CNG03680

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	47.21	1.00e-60	226.00
IUUC-Aml-001597	Ailuropoda melanoleuca	39.27	3.00e-68	251.00
IUUC-Atr-002955	Amborella trichopoda	47.21	2.00e-62	232.00
IUUC-Apl-003249	Anas platyrhynchos	46.62	2.00e-72	265.00
IUUC-Aca-004261	Anolis carolinensis	46.62	1.00e-72	266.00
IUUC-Aly-005456	Arabidopsis lyrata	51.42	2.00e-61	229.00
IUUC-Ath-007560	Arabidopsis thaliana	52.21	2.00e-65	242.00
IUUC-Ago-007911	Ashbya gossypii	37.50	1.00e-65	243.00
IUUC-Acl-008284	Aspergillus clavatus	40.07	2.00e-54	206.00
IUUC-Afl-008507	Aspergillus flavus	38.95	1.00e-56	213.00
IUUC-Afu-008878	Aspergillus fumigatus	45.93	1.00e-55	210.00
IUUC-Ani-009479	Aspergillus nidulans	36.68	1.00e-56	213.00
IUUC-Ang-009562	Aspergillus niger	30.08	6.00e-60	224.00
IUUC-Aor-009949	Aspergillus oryzae	38.95	2.00e-56	212.00
IUUC-Ate-010323	Aspergillus terreus	37.99	5.00e-57	214.00
IUUC-Ame-010757	Astyanax mexicanus	39.68	2.00e-72	265.00
IUUC-Bgr-012277	Blumeria graminis	36.16	6.00e-63	234.00
IUUC-Bta-012929	Bos taurus	39.38	8.00e-69	253.00
IUUC-Bci-013993	Botrytis cinerea	36.36	2.00e-71	262.00
IUUC-Bdi-014013	Brachypodium distachyon	34.80	2.00e-73	268.00
IUUC-Bol-015570	Brassica oleracea	45.85	7.00e-67	246.00
IUUC-Bra-017397	Brassica rapa	44.74	3.00e-61	228.00
IUUC-Cel-018203	Caenorhabditis elegans	53.06	1.00e-56	213.00
IUUC-Cja-019222	Callithrix jacchus	46.45	3.00e-72	265.00
IUUC-Cfa-020599	Canis familiaris	39.38	2.00e-69	256.00
IUUC-Cpo-022071	Cavia porcellus	46.45	5.00e-72	264.00
IUUC-Csa-023770	Chlorocebus sabaeus	43.38	5.00e-68	250.00
IUUC-Cho-024595	Choloepus hoffmanni	42.05	6.00e-64	237.00
IUUC-Cin-025292	Ciona intestinalis	30.56	5.00e-65	240.00
IUUC-Csv-026109	Ciona savignyi	40.77	6.00e-64	237.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	36.14	3.00e-66	246.00
IUUC-Cme-027338	Cyanidioschyzon merolae	41.99	1.00e-66	246.00
IUUC-Dre-027398	Danio rerio	47.27	6.00e-71	260.00
IUUC-Dno-029025	Dasypus novemcinctus	46.45	2.00e-72	265.00
IUUC-Dor-031038	Dipodomys ordii	49.78	9.00e-64	236.00
IUUC-Dse-031432	Dothistroma septosporum	38.21	2.00e-66	246.00
IUUC-Dme-032094	Drosophila melanogaster	37.41	1.00e-49	191.00
IUUC-Ete-032970	Echinops telfairi	49.33	4.00e-62	231.00
IUUC-Eca-034012	Equus caballus	37.68	9.00e-67	246.00
IUUC-Eeu-034488	Erinaceus europaeus	46.45	2.00e-72	265.00
IUUC-Fca-035373	Felis catus	39.09	1.00e-68	252.00
IUUC-Fal-036618	Ficedula albicollis	46.62	1.00e-72	266.00
IUUC-Fox-037986	Fusarium oxysporum	37.40	2.00e-65	242.00
IUUC-Fso-038291	Fusarium solani	36.43	4.00e-66	245.00
IUUC-Gmo-038866	Gadus morhua	46.18	2.00e-70	259.00
IUUC-Ggr-039740	Gaeumannomyces graminis	37.08	8.00e-68	251.00
IUUC-Gga-040729	Gallus gallus	38.12	1.00e-68	252.00
IUUC-Gac-041679	Gasterosteus aculeatus	39.04	5.00e-73	267.00
IUUC-Gma-043368	Glycine max	42.21	3.00e-61	228.00
IUUC-Ggo-045002	Gorilla gorilla	46.45	3.00e-72	265.00
IUUC-Hsa-046052	Homo sapiens	46.45	3.00e-72	265.00
IUUC-Hvu-047108	Hordeum vulgare	41.88	9.00e-60	223.00
IUUC-Itr-048610	Ictidomys tridecemlineatus	38.81	3.00e-67	248.00
IUUC-Kpa-049332	Komagataella pastoris	30.07	1.00e-70	259.00
IUUC-Lch-050107	Latimeria chalumnae	35.81	6.00e-74	270.00
IUUC-Lpe-051424	Leersia perrieri	36.07	1.00e-75	276.00
IUUC-Loc-051800	Lepisosteus oculatus	39.06	1.00e-71	262.00
IUUC-Lma-052981	Leptosphaeria maculans	36.15	1.00e-61	231.00
IUUC-Laf-053645	Loxodonta africana	46.45	7.00e-73	266.00
IUUC-Mcc-055556	Macaca mulatta	43.38	8.00e-68	250.00
IUUC-Meu-056742	Macropus eugenii	40.61	1.00e-67	249.00
IUUC-Mor-056985	Magnaporthe oryzae	38.15	1.00e-67	250.00
IUUC-Mpo-057486	Magnaporthe poae	36.12	2.00e-67	249.00
IUUC-Mtr-058489	Medicago truncatula	43.36	1.00e-59	223.00
IUUC-Mla-058848	Melampsora laricipopulina	43.17	1.00e-85	309.00
IUUC-Mga-060162	Meleagris gallopavo	46.62	1.00e-72	266.00
IUUC-Mvi-060324	Microbotryum violaceum	47.31	1.00e-98	353.00
IUUC-Mmr-061105	Microcebus murinus	46.45	3.00e-72	265.00
IUUC-Mdo-061848	Monodelphis domestica	38.92	1.00e-67	249.00
IUUC-Mmu-063960	Mus musculus	39.09	1.00e-69	256.00
IUUC-Mac-064956	Musa acuminata	42.62	5.00e-73	267.00
IUUC-Mpu-066920	Mustela putorius furo	39.38	1.00e-68	252.00
IUUC-Mlu-068088	Myotis lucifugus	38.61	2.00e-68	252.00
IUUC-Nfi-068330	Neosartorya fischeri	38.62	2.00e-56	213.00
IUUC-Ncr-068879	Neurospora crassa	38.16	5.00e-68	251.00
IUUC-Nle-069874	Nomascus leucogenys	46.45	3.00e-72	264.00
IUUC-Opr-070740	Ochotona princeps	38.81	5.00e-68	251.00
IUUC-Ont-071834	Oreochromis niloticus	40.76	2.00e-74	272.00
IUUC-Oan-073363	Ornithorhynchus anatinus	34.90	2.00e-67	249.00
IUUC-Ocu-074573	Oryctolagus cuniculus	46.45	1.00e-72	266.00
IUUC-Oba-075427	Oryza barthii	48.00	7.00e-68	250.00
IUUC-Obr-076902	Oryza brachyantha	46.08	4.00e-71	261.00
IUUC-Ogl-077583	Oryza glaberrima	48.50	4.00e-62	231.00
IUUC-Ogu-078422	Oryza glumaepatula	48.00	7.00e-68	250.00
IUUC-Oin-079453	Oryza indica	48.38	4.00e-71	260.00
IUUC-Olo-080315	Oryza longistaminata	33.46	2.00e-72	265.00
IUUC-Ome-081271	Oryza meridionalis	48.38	3.00e-71	261.00
IUUC-Oni-082834	Oryza nivara	48.00	7.00e-68	250.00
IUUC-Opu-083691	Oryza punctata	44.12	8.00e-67	246.00
IUUC-Oru-084820	Oryza rufipogon	48.00	7.00e-68	250.00
IUUC-Osa-086139	Oryza sativa	48.38	6.00e-71	260.00
IUUC-Ola-086500	Oryzias latipes	35.56	1.00e-78	285.00
IUUC-Olu-087717	Ostreococcus lucimarinus	43.87	1.00e-62	232.00
IUUC-Oga-089022	Otolemur garnettii	46.45	5.00e-72	264.00
IUUC-Oar-090439	Ovis aries	39.66	9.00e-70	256.00
IUUC-Ptr-091319	Pan troglodytes	46.45	4.00e-72	264.00
IUUC-Pan-092717	Papio anubis	43.38	3.00e-68	251.00
IUUC-Psi-093849	Pelodiscus sinensis	39.07	5.00e-72	264.00
IUUC-Pma-094533	Petromyzon marinus	42.69	3.00e-75	274.00
IUUC-Pno-094890	Phaeosphaeria nodorum	31.05	4.00e-63	235.00
IUUC-Ppa-095584	Physcomitrella patens	28.78	6.00e-20	91.70
IUUC-Pfo-096414	Poecilia formosa	48.25	5.00e-73	267.00
IUUC-Pab-098664	Pongo abelii	46.45	3.00e-72	265.00
IUUC-Pop-099313	Populus trichocarpa	35.77	2.00e-73	268.00
IUUC-Pca-100161	Procavia capensis	38.24	2.00e-65	242.00
IUUC-Ppe-101587	Prunus persica	33.99	1.00e-65	242.00
IUUC-Pva-103244	Pteropus vampyrus	34.05	2.00e-68	252.00
IUUC-Pgr-103546	Puccinia graminis	32.37	2.00e-79	289.00
IUUC-Ptt-103847	Puccinia triticina	38.88	1.00e-76	280.00
IUUC-Pte-104102	Pyrenophora teres	37.27	7.00e-59	221.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	44.86	1.00e-56	214.00
IUUC-Rno-106081	Rattus norvegicus	39.09	2.00e-69	255.00
IUUC-Sce-106170	Saccharomyces cerevisiae	35.75	1.00e-63	237.00
IUUC-Sha-107393	Sarcophilus harrisii	46.26	5.00e-72	264.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	32.74	2.00e-76	278.00
IUUC-Spo-108291	Schizosaccharomyces pombe	39.89	6.00e-71	260.00
IUUC-Smo-109356	Selaginella moellendorffii	51.16	6.00e-64	236.00
IUUC-Sit-109948	Setaria italica	35.02	2.00e-68	252.00
IUUC-Sly-111891	Solanum lycopersicum	43.87	1.00e-59	223.00
IUUC-Stu-112671	Solanum tuberosum	55.92	5.00e-64	237.00
IUUC-Sar-113498	Sorex araneus	39.62	3.00e-72	265.00
IUUC-Sbi-114874	Sorghum bicolor	33.51	2.00e-70	258.00
IUUC-Sre-115130	Sporisorium reilianum	46.37	3.00e-96	345.00
IUUC-Ssc-115637	Sus scrofa	39.38	8.00e-69	253.00
IUUC-Tgu-117267	Taeniopygia guttata	49.60	7.00e-63	233.00
IUUC-Tru-117788	Takifugu rubripes	34.74	1.00e-79	289.00
IUUC-Tsy-119414	Tarsius syrichta	45.45	2.00e-68	251.00
IUUC-Tni-120093	Tetraodon nigroviridis	33.78	1.00e-75	276.00
IUUC-Tca-121001	Theobroma cacao	35.27	2.00e-71	262.00
IUUC-Tre-121888	Trichoderma reesei	36.91	1.00e-65	243.00
IUUC-Tvi-122422	Trichoderma virens	35.88	4.00e-61	228.00
IUUC-Tae-125401	Triticum aestivum	33.97	6.00e-73	267.00
IUUC-Tur-126392	Triticum urartu	53.00	7.00e-58	216.00
IUUC-Tme-127062	Tuber melanosporum	32.20	5.00e-73	268.00
IUUC-Tbe-127672	Tupaia belangeri	46.45	6.00e-73	267.00
IUUC-Ttr-128441	Tursiops truncatus	46.45	1.00e-72	266.00
IUUC-Uma-129498	Ustilago maydis	37.17	1.00e-146	512.00
IUUC-Vda-129781	Verticillium dahliae	38.93	2.00e-69	256.00
IUUC-Vpa-130571	Vicugna pacos	38.81	6.00e-68	250.00
IUUC-Vvi-131066	Vitis vinifera	45.39	8.00e-61	226.00
IUUC-Xtr-132305	Xenopus tropicalis	45.49	3.00e-71	261.00
IUUC-Xma-133838	Xiphophorus maculatus	35.58	8.00e-77	280.00
IUUC-Yli-134392	Yarrowia lipolytica	37.00	3.00e-64	238.00
IUUC-Zma-135699	Zea mays	33.69	1.00e-69	256.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence