iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115440

Ensembl Protein ID

ENSSSCP00000022486.1

UniProt Accession

I3LEJ8; I3LEJ8_PIG

Genbank Protein ID

ENSSSCP00000022486

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP236234

Gene Name

PIK3R4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000029094.1	ENSSSCT00000025472.1	ENSSSCP00000022486.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-15	54.9	989	1018

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ v+ ++  ++  l++++s+Dgt+k+W+
   Q: 989  HKSAVNRIQVsDEhSLFATCSNDGTVKIWN 1018
           9999****99544788*************9 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MGNQLAGIAP SQILSVESYF SDIHDFEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60
TLPLTSYKQE LEELKIRLHS AQNCLPFQKA VEKASEKAAM LFRQYVRDNL YDRISTRPFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCGCTCCG CGACAGGAAG TGAGGTCAGA GCCGGCAGCT TTCCCGGGAG TTCGGCTTTG 60
CGGCGTCTGC AGCTGGAGAA GCCGAGTTTC CCAGGACGTG GCCACCTTCC TCTCTCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00069--Pkinase
PF00400--WD40

SMART

SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005770--C:late endosome
GO:0015630--C:microtubule cytoskeleton
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole
GO:0032801--P:receptor catabolic process
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000213	Aegilops tauschii	31.68	6.00e-43	169.00
IUUC-Aml-001659	Ailuropoda melanoleuca	96.32	0.00e+00	2659.00
IUUC-Atr-002968	Amborella trichopoda	46.80	2.00e-48	187.00
IUUC-Apl-003418	Anas platyrhynchos	90.55	0.00e+00	2558.00
IUUC-Aca-004344	Anolis carolinensis	89.84	0.00e+00	2276.00
IUUC-Aly-006107	Arabidopsis lyrata	46.22	2.00e-68	254.00
IUUC-Ath-007260	Arabidopsis thaliana	46.53	4.00e-69	256.00
IUUC-Ago-007721	Ashbya gossypii	39.56	7.00e-56	213.00
IUUC-Acl-008378	Aspergillus clavatus	36.73	2.00e-145	510.00
IUUC-Afl-008632	Aspergillus flavus	35.17	3.00e-139	489.00
IUUC-Afu-009020	Aspergillus fumigatus	35.64	1.00e-138	488.00
IUUC-Ani-009204	Aspergillus nidulans	35.21	2.00e-128	453.00
IUUC-Ang-009811	Aspergillus niger	34.81	1.00e-136	481.00
IUUC-Aor-010168	Aspergillus oryzae	35.17	3.00e-139	489.00
IUUC-Ate-010556	Aspergillus terreus	35.14	2.00e-137	484.00
IUUC-Ame-011955	Astyanax mexicanus	80.23	0.00e+00	1794.00
IUUC-Bgr-012050	Blumeria graminis	36.27	1.00e-137	484.00
IUUC-Bta-012432	Bos taurus	95.58	0.00e+00	2673.00
IUUC-Bci-013846	Botrytis cinerea	34.31	3.00e-139	489.00
IUUC-Bdi-015072	Brachypodium distachyon	43.43	1.00e-64	242.00
IUUC-Bol-015314	Brassica oleracea	46.83	3.00e-69	257.00
IUUC-Bra-017476	Brassica rapa	46.83	4.00e-69	256.00
IUUC-Cel-018550	Caenorhabditis elegans	32.02	2.00e-86	314.00
IUUC-Cja-019538	Callithrix jacchus	95.51	0.00e+00	2676.00
IUUC-Cfa-020483	Canis familiaris	96.17	0.00e+00	2665.00
IUUC-Cpo-021392	Cavia porcellus	95.14	0.00e+00	2665.00
IUUC-Csa-024112	Chlorocebus sabaeus	96.03	0.00e+00	2684.00
IUUC-Cho-025015	Choloepus hoffmanni	88.28	0.00e+00	921.00
IUUC-Cin-025209	Ciona intestinalis	41.06	0.00e+00	1060.00
IUUC-Csv-026334	Ciona savignyi	41.63	0.00e+00	876.00
IUUC-Cgl-026447	Colletotrichum gloeosporioides	35.54	7.00e-141	495.00
IUUC-Cne-026999	Cryptococcus neoformans	34.70	8.00e-115	408.00
IUUC-Dre-028662	Danio rerio	81.09	0.00e+00	2278.00
IUUC-Dno-029545	Dasypus novemcinctus	93.97	0.00e+00	2612.00
IUUC-Dor-030941	Dipodomys ordii	65.92	0.00e+00	727.00
IUUC-Dse-031455	Dothistroma septosporum	36.05	1.00e-134	474.00
IUUC-Dme-031726	Drosophila melanogaster	47.39	0.00e+00	750.00
IUUC-Ete-033147	Echinops telfairi	91.48	0.00e+00	972.00
IUUC-Eca-034025	Equus caballus	96.32	0.00e+00	2689.00
IUUC-Eeu-034480	Erinaceus europaeus	88.64	0.00e+00	1491.00
IUUC-Fca-035741	Felis catus	95.66	0.00e+00	2654.00
IUUC-Fal-037666	Ficedula albicollis	89.66	0.00e+00	2540.00
IUUC-Fox-037818	Fusarium oxysporum	33.45	9.00e-124	438.00
IUUC-Fso-038086	Fusarium solani	33.67	8.00e-127	448.00
IUUC-Gmo-038804	Gadus morhua	80.05	0.00e+00	729.00
IUUC-Ggr-039800	Gaeumannomyces graminis	35.50	5.00e-131	462.00
IUUC-Gga-041251	Gallus gallus	89.41	0.00e+00	1989.00
IUUC-Gac-042376	Gasterosteus aculeatus	78.21	0.00e+00	2197.00
IUUC-Gma-044095	Glycine max	45.73	4.00e-71	263.00
IUUC-Ggo-044506	Gorilla gorilla	95.44	0.00e+00	2667.00
IUUC-Hsa-045871	Homo sapiens	96.03	0.00e+00	2681.00
IUUC-Hvu-047648	Hordeum vulgare	30.81	3.00e-44	173.00
IUUC-Itr-048082	Ictidomys tridecemlineatus	96.19	0.00e+00	1176.00
IUUC-Kpa-049390	Komagataella pastoris	32.80	5.00e-127	449.00
IUUC-Lch-050284	Latimeria chalumnae	84.43	0.00e+00	2308.00
IUUC-Lpe-050880	Leersia perrieri	41.93	7.00e-63	236.00
IUUC-Loc-052815	Lepisosteus oculatus	80.95	0.00e+00	2279.00
IUUC-Lma-053324	Leptosphaeria maculans	36.13	3.00e-144	506.00
IUUC-Laf-054204	Loxodonta africana	83.85	0.00e+00	2259.00
IUUC-Mcc-054612	Macaca mulatta	96.10	0.00e+00	2684.00
IUUC-Meu-056227	Macropus eugenii	86.30	0.00e+00	853.00
IUUC-Mor-057094	Magnaporthe oryzae	35.95	9.00e-133	468.00
IUUC-Mtr-058550	Medicago truncatula	43.80	3.00e-70	260.00
IUUC-Mla-058893	Melampsora laricipopulina	35.01	1.00e-129	458.00
IUUC-Mga-059474	Meleagris gallopavo	89.38	0.00e+00	2401.00
IUUC-Mvi-060227	Microbotryum violaceum	45.74	4.00e-84	306.00
IUUC-Mmr-061543	Microcebus murinus	88.74	0.00e+00	2399.00
IUUC-Mdo-062129	Monodelphis domestica	92.02	0.00e+00	2494.00
IUUC-Mmu-064381	Mus musculus	93.89	0.00e+00	2632.00
IUUC-Mac-064455	Musa acuminata	38.68	2.00e-120	427.00
IUUC-Mpu-066151	Mustela putorius furo	97.33	0.00e+00	975.00
IUUC-Mlu-067824	Myotis lucifugus	96.10	0.00e+00	2680.00
IUUC-Nfi-068241	Neosartorya fischeri	36.56	1.00e-142	501.00
IUUC-Ncr-068964	Neurospora crassa	35.58	8.00e-137	481.00
IUUC-Nle-069152	Nomascus leucogenys	96.10	0.00e+00	2684.00
IUUC-Opr-070870	Ochotona princeps	84.62	0.00e+00	1426.00
IUUC-Ont-071293	Oreochromis niloticus	79.62	0.00e+00	2248.00
IUUC-Oan-072852	Ornithorhynchus anatinus	86.82	0.00e+00	2395.00
IUUC-Ocu-074727	Oryctolagus cuniculus	95.88	0.00e+00	2651.00
IUUC-Oba-075932	Oryza barthii	39.85	1.00e-62	234.00
IUUC-Obr-076424	Oryza brachyantha	46.83	2.00e-59	224.00
IUUC-Ogl-077491	Oryza glaberrima	39.85	1.00e-62	234.00
IUUC-Ogu-078933	Oryza glumaepatula	33.37	3.00e-96	346.00
IUUC-Oin-079604	Oryza indica	44.29	6.00e-68	252.00
IUUC-Olo-080850	Oryza longistaminata	35.56	1.00e-113	404.00
IUUC-Ome-081860	Oryza meridionalis	44.29	5.00e-68	253.00
IUUC-Oni-082895	Oryza nivara	39.85	3.00e-62	233.00
IUUC-Opu-083741	Oryza punctata	44.00	1.00e-66	248.00
IUUC-Oru-084616	Oryza rufipogon	39.54	7.00e-62	233.00
IUUC-Osa-085941	Oryza sativa	28.01	7.00e-35	141.00
IUUC-Ola-087357	Oryzias latipes	84.98	1.00e-156	545.00
IUUC-Olu-087659	Ostreococcus lucimarinus	30.19	1.00e-87	318.00
IUUC-Oga-088555	Otolemur garnettii	96.10	0.00e+00	2668.00
IUUC-Oar-089304	Ovis aries	94.41	0.00e+00	1293.00
IUUC-Ptr-091140	Pan troglodytes	96.10	0.00e+00	2684.00
IUUC-Pan-092413	Papio anubis	95.74	0.00e+00	2576.00
IUUC-Psi-093210	Pelodiscus sinensis	90.16	0.00e+00	2544.00
IUUC-Pma-094674	Petromyzon marinus	57.23	0.00e+00	738.00
IUUC-Pno-094969	Phaeosphaeria nodorum	30.81	8.00e-143	501.00
IUUC-Ppa-096017	Physcomitrella patens	46.00	3.00e-75	277.00
IUUC-Pfo-096077	Poecilia formosa	79.47	0.00e+00	2209.00
IUUC-Pab-098269	Pongo abelii	95.14	0.00e+00	2661.00
IUUC-Pop-100052	Populus trichocarpa	44.09	4.00e-62	233.00
IUUC-Pca-100377	Procavia capensis	90.41	0.00e+00	2421.00
IUUC-Ppe-101445	Prunus persica	46.25	2.00e-70	261.00
IUUC-Pva-102198	Pteropus vampyrus	96.37	0.00e+00	1768.00
IUUC-Pgr-103544	Puccinia graminis	47.65	3.00e-80	293.00
IUUC-Ptt-103964	Puccinia triticina	47.65	5.00e-80	293.00
IUUC-Pte-104196	Pyrenophora teres	35.43	8.00e-136	478.00
IUUC-Pyt-104544	Pyrenophora triticirepentis	31.54	1.00e-170	593.00
IUUC-Rno-105256	Rattus norvegicus	93.82	0.00e+00	2629.00
IUUC-Sce-106295	Saccharomyces cerevisiae	32.88	8.00e-112	398.00
IUUC-Sha-107597	Sarcophilus harrisii	91.42	0.00e+00	2528.00
IUUC-Sja-107781	Schizosaccharomyces japonicus	32.95	6.00e-97	349.00
IUUC-Spo-108031	Schizosaccharomyces pombe	44.01	8.00e-72	266.00
IUUC-Ssl-108579	Sclerotinia sclerotiorum	35.26	7.00e-133	468.00
IUUC-Smo-108679	Selaginella moellendorffii	43.89	8.00e-75	275.00
IUUC-Sit-110765	Setaria italica	42.00	5.00e-62	233.00
IUUC-Sly-111527	Solanum lycopersicum	44.08	2.00e-71	264.00
IUUC-Stu-112899	Solanum tuberosum	44.08	2.00e-71	265.00
IUUC-Sar-112986	Sorex araneus	95.29	0.00e+00	2663.00
IUUC-Sbi-114604	Sorghum bicolor	41.44	6.00e-65	243.00
IUUC-Sre-115191	Sporisorium reilianum	43.87	1.00e-65	245.00
IUUC-Tgu-116633	Taeniopygia guttata	89.81	0.00e+00	2543.00
IUUC-Tru-118439	Takifugu rubripes	78.21	0.00e+00	2214.00
IUUC-Tsy-119472	Tarsius syrichta	88.32	0.00e+00	1400.00
IUUC-Tni-119808	Tetraodon nigroviridis	74.66	0.00e+00	2021.00
IUUC-Tca-121648	Theobroma cacao	47.15	6.00e-72	266.00
IUUC-Tre-122161	Trichoderma reesei	33.71	4.00e-121	429.00
IUUC-Tvi-122575	Trichoderma virens	32.43	5.00e-113	402.00
IUUC-Tae-123381	Triticum aestivum	47.12	4.00e-65	243.00
IUUC-Tur-126291	Triticum urartu	44.00	2.00e-65	244.00
IUUC-Tme-126979	Tuber melanosporum	37.24	6.00e-148	518.00
IUUC-Tbe-127576	Tupaia belangeri	80.21	0.00e+00	915.00
IUUC-Ttr-129106	Tursiops truncatus	96.52	0.00e+00	1286.00
IUUC-Uma-129633	Ustilago maydis	42.72	7.00e-74	273.00
IUUC-Vda-130001	Verticillium dahliae	34.76	4.00e-127	449.00
IUUC-Vpa-130733	Vicugna pacos	87.99	0.00e+00	1284.00
IUUC-Vvi-131318	Vitis vinifera	44.48	1.00e-69	258.00
IUUC-Xtr-131908	Xenopus tropicalis	85.22	0.00e+00	2427.00
IUUC-Xma-133331	Xiphophorus maculatus	79.47	0.00e+00	2220.00
IUUC-Yli-134651	Yarrowia lipolytica	36.97	1.00e-119	424.00
IUUC-Zma-135850	Zea mays	41.18	6.00e-66	246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence