iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088258

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03024696

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012313.2	ENSOGAT00000012318.2	ENSOGAP00000011017.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.30e-76	255.2	34	319

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN++LQcL +i++l e++l+ k+  +l+     ++  e++++++ l++ +w +++  vsp+ + +al+++ + f +  
   Q: 34   TGLRNLGNTCYMNAILQCLCSISPLVEYFLSgKYMTALQ-----KDCSEVATAFAYLMTDMWLGDSDCVSPEIFRSALGNLYPAFMKKT 117
           7******************************44444444.....5678***************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+lkk   +++++ ++ +k++  +   +k    ++s+i++lF+gql  +i+cl+c+n + r+e f+ lslp+p
   Q: 118  QQDAQEFLIYVLNELHEALKK---TQYHRRRSYEKRS-IQRCCRKVIANETSIITRLFEGQLNYSIVCLKCENCTYRNEVFTVLSLPIP 202
           *******************44...5555555555444.455578999999*************************************** PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
            + e+   slqdcL+ f+++++l+ +n++ c  c+ +qe+  + +++k P+++++hLkRf  + ++++++k+ +++++pl+ Ldl+++ 
   Q: 203  CEYEC---SLQDCLQCFFQQDTLTWNNQIRCAFCETNQETAVRASISKAPKIIVFHLKRF--DIQGMMKRKLRTNIHYPLTnLDLTSYI 286
           *****...****************************************************..7788*********************** PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvkn 301
           +   +k   + kY+L+avv+H G l++GHY+a++kn
   Q: 287  CPIFRK---HPKYNLCAVVNHFGDLDGGHYTAFCKN 319
           **7765...79************************9 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

SFSVDQHSAE CTDNYDPLPV NEPDESQPHF QGVTGLRNLG NTCYMNAILQ CLCSISPLVE 60
YFLSGKYMTA LQKDCSEVAT AFAYLMTDMW LGDSDCVSPE IFRSALGNLY PAFMKKTQQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTTCTCTG TGGACCAACA CAGCGCAGAG TGCACAGATA ACTATGACCC CCTTCCAGTT 60
AACGAGCCTG ATGAGAGCCA GCCCCATTTC CAGGGTGTGA CGGGCCTGCG GAACTTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	88.61	6.00e-170	589.00
IUUC-Aca-005256	Anolis carolinensis	50.15	1.00e-86	312.00
IUUC-Bta-012753	Bos taurus	83.90	1.00e-161	561.00
IUUC-Cfa-020054	Canis familiaris	85.14	3.00e-167	580.00
IUUC-Cpo-021375	Cavia porcellus	78.09	2.00e-152	531.00
IUUC-Csa-023902	Chlorocebus sabaeus	87.62	5.00e-102	363.00
IUUC-Cho-024755	Choloepus hoffmanni	75.08	3.00e-137	480.00
IUUC-Dor-030311	Dipodomys ordii	85.87	4.00e-92	331.00
IUUC-Ete-032570	Echinops telfairi	63.95	5.00e-106	377.00
IUUC-Eca-034343	Equus caballus	87.31	4.00e-169	587.00
IUUC-Eeu-034510	Erinaceus europaeus	85.00	4.00e-164	570.00
IUUC-Fca-035920	Felis catus	85.14	1.00e-166	578.00
IUUC-Fal-036903	Ficedula albicollis	58.56	3.00e-95	341.00
IUUC-Gac-042261	Gasterosteus aculeatus	41.86	6.00e-62	231.00
IUUC-Hsa-046665	Homo sapiens	81.63	5.00e-159	553.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	92.41	2.00e-177	615.00
IUUC-Lch-049925	Latimeria chalumnae	54.97	1.00e-93	336.00
IUUC-Loc-051880	Lepisosteus oculatus	47.35	5.00e-71	262.00
IUUC-Laf-054494	Loxodonta africana	89.24	5.00e-171	593.00
IUUC-Mcc-055507	Macaca mulatta	88.92	2.00e-169	588.00
IUUC-Meu-055906	Macropus eugenii	75.31	3.00e-145	508.00
IUUC-Mmr-061564	Microcebus murinus	63.66	6.00e-104	370.00
IUUC-Mdo-061800	Monodelphis domestica	77.71	6.00e-148	516.00
IUUC-Mmu-063618	Mus musculus	83.23	3.00e-157	547.00
IUUC-Mpu-066699	Mustela putorius furo	87.00	1.00e-169	589.00
IUUC-Mlu-067672	Myotis lucifugus	85.76	1.00e-163	568.00
IUUC-Opr-070949	Ochotona princeps	84.95	6.00e-151	526.00
IUUC-Oan-073725	Ornithorhynchus anatinus	65.52	4.00e-121	427.00
IUUC-Ocu-074021	Oryctolagus cuniculus	91.77	1.00e-176	612.00
IUUC-Oar-089881	Ovis aries	86.69	2.00e-168	585.00
IUUC-Ptr-090988	Pan troglodytes	81.93	1.00e-153	535.00
IUUC-Pan-091773	Papio anubis	88.29	4.00e-167	580.00
IUUC-Psi-093243	Pelodiscus sinensis	73.12	5.00e-121	427.00
IUUC-Pab-097713	Pongo abelii	83.80	5.00e-160	556.00
IUUC-Pca-100226	Procavia capensis	67.99	9.00e-127	446.00
IUUC-Pva-103172	Pteropus vampyrus	87.85	1.00e-169	588.00
IUUC-Rno-105950	Rattus norvegicus	85.13	2.00e-160	558.00
IUUC-Sha-107026	Sarcophilus harrisii	76.85	1.00e-149	522.00
IUUC-Ssc-116383	Sus scrofa	91.14	1.00e-175	608.00
IUUC-Tgu-116511	Taeniopygia guttata	56.21	2.00e-90	325.00
IUUC-Tsy-119444	Tarsius syrichta	91.23	6.00e-61	227.00
IUUC-Tbe-127808	Tupaia belangeri	85.40	2.00e-64	238.00
IUUC-Ttr-129046	Tursiops truncatus	86.92	4.00e-166	577.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence