iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089819

Ensembl Protein ID

ENSOARP00000003343.1

UniProt Accession

W5NYU5; W5NYU5_SHEEP

Genbank Protein ID

ENSOARP00000003343

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01018123

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003140.1	ENSOART00000003407.1	ENSOARP00000003343.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-78	263.6	10	580

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 47   gellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeek 133
           +e++++l+ l+++lw+++ +     e+++a++k+  +f+g++q+Da Efl +lld+++e+l+ +++ p +++ +++ +++s++  +++ 
   Q: 10   AEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGAQFQGNAQHDALEFLLWLLDRVHEDLEGSSRGPGSDKLQSEARKASENlrSPSA 98
           6899*********************************************************9988888888888887777777778889 PP
   S: 134  kkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..................................... 185
           + + ++s+++  Fq q++s+++c++c ++s++++pfl +slp+p ++++ ++                                     
   Q: 99   PLSVGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSvtlvfpsksqrflrvglavpilstvaalrkmvaeegg 187
           999999*****************************************98888************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 188  vspeevilvelypsglqrsffdeedlntiaegdnvyafhappspgqemlsarpsgllvsprlaaregqrlplpihnettvlilfcnlvg 276
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 277  sgqqasrfgppflvredraiswiqlqqcilskvrylmksevpiqnlgslfsirvvglslacsylspqdsrplchwaidralhlrrpggp 365
           ***************************************************************************************** PP
   S: 186  ............................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                       +l++c++ +tkee+l +++++ c++ck++q+ + kl+l++lP++L
   Q: 366  phiklavewdvdtkerlfgspqeervqdadsvrrqqqahqqhscTLDECFQFYTKEEQLAQDDAWRCPHCKALQQGVVKLSLWTLPDIL 454
           ***************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke.....................kkkYeLiavvvHsGslssGHYva 297
           i+hLkRf   + +++r+k+++ v+fpl  Ld++p++++++++ k                      +  Y+L+av++H+Gsl++GHY+a
   Q: 455  IIHLKRF--CQVGERRNKLSTLVKFPLAgLDMAPHVAQRSTSPKAmpgawppswkqpaclptsyppDFLYDLYAVCNHHGSLQGGHYTA 541
           *******..88899************************88887779999999999999******99*********************** PP
   S: 298  yvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           y++n  +g+W+ +dDs+V+++ e+ev++   + aY+lfY++r
   Q: 542  YCRNsLDGQWYSYDDSTVEPLLEDEVNT---RGAYILFYQKR 580
           ****55788*******************...********985 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

GARRGGPGRA EVTEQLAALV RALWTREYTP QLSAEFKNAV SKYGAQFQGN AQHDALEFLL 60
WLLDRVHEDL EGSSRGPGSD KLQSEARKAS ENLRSPSAPL SVGQSFVQSH FQAQYRSSLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGCGCC GGGGGGGCCC GGGCCGCGCC GAGGTCACCG AGCAGCTGGC GGCGCTGGTG 60
CGCGCGCTCT GGACGCGCGA ATACACGCCC CAACTTTCCG CCGAGTTCAA GGTAGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	76.73	0.00e+00	1352.00
IUUC-Aca-004436	Anolis carolinensis	52.02	0.00e+00	783.00
IUUC-Ame-011153	Astyanax mexicanus	49.15	0.00e+00	803.00
IUUC-Bta-013560	Bos taurus	94.83	0.00e+00	1866.00
IUUC-Cja-018737	Callithrix jacchus	76.78	0.00e+00	1427.00
IUUC-Cfa-020347	Canis familiaris	78.00	0.00e+00	1428.00
IUUC-Csa-023656	Chlorocebus sabaeus	77.79	0.00e+00	1452.00
IUUC-Cho-024864	Choloepus hoffmanni	68.77	0.00e+00	801.00
IUUC-Dre-028066	Danio rerio	48.55	0.00e+00	826.00
IUUC-Dno-028855	Dasypus novemcinctus	71.10	0.00e+00	1234.00
IUUC-Dor-030475	Dipodomys ordii	86.55	0.00e+00	701.00
IUUC-Dme-032088	Drosophila melanogaster	36.50	2.00e-93	337.00
IUUC-Eca-034147	Equus caballus	84.86	0.00e+00	1365.00
IUUC-Eeu-034703	Erinaceus europaeus	72.30	2.00e-142	500.00
IUUC-Fca-036550	Felis catus	75.30	0.00e+00	1281.00
IUUC-Gmo-038903	Gadus morhua	52.14	2.00e-178	619.00
IUUC-Gac-042087	Gasterosteus aculeatus	49.90	0.00e+00	797.00
IUUC-Ggo-045171	Gorilla gorilla	78.08	0.00e+00	1457.00
IUUC-Hsa-045961	Homo sapiens	77.99	0.00e+00	1455.00
IUUC-Itr-048673	Ictidomys tridecemlineatus	70.00	0.00e+00	632.00
IUUC-Loc-052852	Lepisosteus oculatus	63.14	0.00e+00	863.00
IUUC-Laf-054033	Loxodonta africana	76.13	0.00e+00	1391.00
IUUC-Mcc-055431	Macaca mulatta	77.39	0.00e+00	1451.00
IUUC-Mmr-061035	Microcebus murinus	78.90	0.00e+00	1459.00
IUUC-Mdo-062172	Monodelphis domestica	64.92	0.00e+00	855.00
IUUC-Mmu-063966	Mus musculus	74.09	0.00e+00	1365.00
IUUC-Mpu-066307	Mustela putorius furo	76.59	0.00e+00	1373.00
IUUC-Nle-070172	Nomascus leucogenys	77.49	0.00e+00	1447.00
IUUC-Opr-070499	Ochotona princeps	68.24	0.00e+00	1229.00
IUUC-Ont-071920	Oreochromis niloticus	49.72	0.00e+00	845.00
IUUC-Ocu-074014	Oryctolagus cuniculus	79.60	0.00e+00	1152.00
IUUC-Ola-086360	Oryzias latipes	60.38	0.00e+00	817.00
IUUC-Oga-088202	Otolemur garnettii	77.22	0.00e+00	1433.00
IUUC-Ptr-091076	Pan troglodytes	77.89	0.00e+00	1454.00
IUUC-Pan-092248	Papio anubis	77.20	0.00e+00	1437.00
IUUC-Pfo-096534	Poecilia formosa	58.28	0.00e+00	744.00
IUUC-Pab-098453	Pongo abelii	77.54	0.00e+00	1445.00
IUUC-Pca-100290	Procavia capensis	59.97	0.00e+00	699.00
IUUC-Pva-102317	Pteropus vampyrus	71.85	0.00e+00	1293.00
IUUC-Rno-104948	Rattus norvegicus	73.90	0.00e+00	1315.00
IUUC-Sha-106558	Sarcophilus harrisii	55.85	0.00e+00	1019.00
IUUC-Sar-113105	Sorex araneus	61.64	0.00e+00	1015.00
IUUC-Ssc-115312	Sus scrofa	84.03	0.00e+00	1599.00
IUUC-Tru-117995	Takifugu rubripes	63.16	0.00e+00	834.00
IUUC-Tsy-119325	Tarsius syrichta	72.08	0.00e+00	709.00
IUUC-Tni-120517	Tetraodon nigroviridis	58.41	0.00e+00	800.00
IUUC-Tbe-127439	Tupaia belangeri	63.98	5.00e-122	432.00
IUUC-Ttr-128829	Tursiops truncatus	77.82	0.00e+00	1459.00
IUUC-Vpa-130306	Vicugna pacos	80.62	9.00e-162	564.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence