iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107943

Ensembl Protein ID

EEB06843

UniProt Accession

B6JZ75; B6JZ75_SCHJY

Genbank Protein ID

EEB06843.1

Protein Name

Ubiquitin-protein ligase E3

Genbank Nucleotide ID

KE651168

Gene Name

SJAG_01900

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_01900	EEB06843	EEB06843

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.60e-83	276.3	1089	1436

Active Site

Position(s)	Description	Evidence
1403	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp..........ehlklFeflGrllgkalqdgrlldlplsk 94
           k+ +e+e+++E g +l G+t+ef++ +s+e+ ++   +++ +++ ++ ++ +   gl +           +  +lF++lG++++ +l+d+rl+ ++l++
   Q: 1089 KNIIEIEYEDEVGSGL-GPTQEFYTTVSREFTRKHHHMWRDDNQTSNYVHSAT--GLFPApmshaiganeKICSLFKMLGQFIARSLYDSRLISVQLNP 1184
           67899***********.**********************77666555555433..3332247788888889**************************** PP
   S: 95   sfyklllgkklsledleevdpelykslkeikena............esdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyr 181
            +++     +l+l+ +++vd+el ksl +++++             e  ++ ++l+l f+     l+ + ++eL+p+G+n++V  +N+++Y++ +++++
   Q: 1185 LIFEET--IPLTLSSVSKVDKELGKSLRFLERLLarqqagftavptE--TKIEDLCLDFT-----LPGYPSVELIPNGRNVQVSHKNASKYISSIIDFT 1274
           ***985..5899*******************9986655555555333..55555666666.....889******************************* PP
   S: 182  lkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGf 279
           + +g++ q+++freGf++v++ e+l++ t +el++l  +  e++++e+++k +  ++gy+ ++ +i++++ev+++fs  e+++fLqF+Tgs +lP+gGf
   Q: 1275 VGKGVQLQIQNFREGFSTVFNYESLRIITSHELSMLFGKVeEDWSFETIAKSIVADHGYNMENTTIHNLIEVMSNFSFSEQRDFLQFITGSRKLPIGGF 1373
           ***********************************999989********************************************************** PP
   S: 280  aelkprlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
            +l+p l+v+rk     +  dd lPs++TC+nyLkLPeYsskeilk+kL++A++e+  +F+ls
   Q: 1374 SSLHPALTVVRKlneppYVPDDYLPSVMTCVNYLKLPEYSSKEILKQKLMLAMKEGqGSFHLS 1436
           **************9999999***********************************9999985 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MNTNEHDMAT ELDNDMFSNP EDESHDVSYR SAGAQLNGNG DDFDIHVIDS DAPAHEHMTS 60
SVDDHDEGVS DEEEDEEEEE EEEEDEAVDE DMSGEDDHRY NNYYSESYES DESEVDMRRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCGCCCACA CCTGCCGTCC ACAATCATCC ACAAAATACA TTTCAAGAAA AATTGTTAGT 60
TTTTTACTCA TAGACGATTA GTGCTGTGGT TAAGAACACT TTTTATAAGT TCTTTCTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	38.58	1.00e-96	346.00
IUUC-Aml-001502	Ailuropoda melanoleuca	37.58	3.00e-95	342.00
IUUC-Atr-002821	Amborella trichopoda	36.21	1.00e-89	323.00
IUUC-Apl-003531	Anas platyrhynchos	36.77	3.00e-90	325.00
IUUC-Aca-004521	Anolis carolinensis	37.07	7.00e-36	145.00
IUUC-Aly-005962	Arabidopsis lyrata	39.49	7.00e-96	344.00
IUUC-Ath-006636	Arabidopsis thaliana	39.22	9.00e-95	340.00
IUUC-Ago-007875	Ashbya gossypii	34.39	1.00e-115	409.00
IUUC-Acl-008242	Aspergillus clavatus	43.66	3.00e-146	511.00
IUUC-Afl-008736	Aspergillus flavus	43.68	6.00e-142	497.00
IUUC-Afu-008812	Aspergillus fumigatus	42.83	6.00e-143	500.00
IUUC-Ani-009407	Aspergillus nidulans	43.35	4.00e-143	501.00
IUUC-Ang-009763	Aspergillus niger	42.02	1.00e-134	473.00
IUUC-Aor-009941	Aspergillus oryzae	40.32	1.00e-153	536.00
IUUC-Ate-010459	Aspergillus terreus	40.89	3.00e-117	415.00
IUUC-Ame-011761	Astyanax mexicanus	39.52	6.00e-98	351.00
IUUC-Bgr-012265	Blumeria graminis	45.84	5.00e-137	481.00
IUUC-Bta-013070	Bos taurus	37.58	3.00e-95	342.00
IUUC-Bci-013890	Botrytis cinerea	50.00	1.00e-137	483.00
IUUC-Bdi-014046	Brachypodium distachyon	38.29	2.00e-94	339.00
IUUC-Bol-015942	Brassica oleracea	38.31	3.00e-95	342.00
IUUC-Bra-016849	Brassica rapa	38.51	2.00e-95	342.00
IUUC-Cel-018153	Caenorhabditis elegans	30.18	5.00e-65	242.00
IUUC-Cja-019046	Callithrix jacchus	37.58	4.00e-95	342.00
IUUC-Cfa-020521	Canis familiaris	37.37	9.00e-95	340.00
IUUC-Cpo-021639	Cavia porcellus	37.78	6.00e-95	341.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	36.22	3.00e-86	310.00
IUUC-Csa-023231	Chlorocebus sabaeus	37.58	3.00e-95	342.00
IUUC-Cho-024380	Choloepus hoffmanni	33.47	2.00e-78	286.00
IUUC-Cin-025482	Ciona intestinalis	35.83	3.00e-91	327.00
IUUC-Csv-026121	Ciona savignyi	35.16	2.00e-89	322.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	41.86	5.00e-137	480.00
IUUC-Cne-026857	Cryptococcus neoformans	39.08	5.00e-115	407.00
IUUC-Cme-027226	Cyanidioschyzon merolae	30.18	1.00e-62	233.00
IUUC-Dre-028174	Danio rerio	39.80	1.00e-98	353.00
IUUC-Dno-029954	Dasypus novemcinctus	38.21	1.00e-35	144.00
IUUC-Dor-030939	Dipodomys ordii	34.14	2.00e-79	289.00
IUUC-Dse-031444	Dothistroma septosporum	43.54	5.00e-141	494.00
IUUC-Dme-032162	Drosophila melanogaster	38.25	3.00e-52	200.00
IUUC-Ete-032345	Echinops telfairi	31.31	3.00e-66	246.00
IUUC-Eca-033229	Equus caballus	37.58	3.00e-95	342.00
IUUC-Eeu-035205	Erinaceus europaeus	37.78	6.00e-93	334.00
IUUC-Fca-036444	Felis catus	37.58	6.00e-95	341.00
IUUC-Fal-037131	Ficedula albicollis	37.98	2.00e-96	346.00
IUUC-Fox-038035	Fusarium oxysporum	46.20	1.00e-138	485.00
IUUC-Fso-038320	Fusarium solani	43.79	3.00e-140	491.00
IUUC-Gmo-039497	Gadus morhua	38.38	4.00e-98	352.00
IUUC-Ggr-040057	Gaeumannomyces graminis	43.74	1.00e-141	496.00
IUUC-Gga-041021	Gallus gallus	37.98	9.00e-97	347.00
IUUC-Gac-042474	Gasterosteus aculeatus	39.11	7.00e-98	350.00
IUUC-Gma-043715	Glycine max	39.42	7.00e-96	344.00
IUUC-Ggo-044855	Gorilla gorilla	37.58	4.00e-95	342.00
IUUC-Hsa-046147	Homo sapiens	37.58	4.00e-95	342.00
IUUC-Hvu-047775	Hordeum vulgare	37.50	2.00e-92	332.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	37.58	9.00e-95	340.00
IUUC-Kpa-049098	Komagataella pastoris	44.79	7.00e-115	407.00
IUUC-Lch-049818	Latimeria chalumnae	37.53	1.00e-94	340.00
IUUC-Lpe-051017	Leersia perrieri	35.15	2.00e-87	316.00
IUUC-Loc-051777	Lepisosteus oculatus	38.66	1.00e-97	350.00
IUUC-Lma-052990	Leptosphaeria maculans	43.49	3.00e-142	498.00
IUUC-Laf-053727	Loxodonta africana	37.78	2.00e-95	342.00
IUUC-Mcc-055799	Macaca mulatta	37.58	5.00e-95	341.00
IUUC-Meu-056065	Macropus eugenii	33.10	2.00e-68	253.00
IUUC-Mor-057054	Magnaporthe oryzae	45.35	2.00e-137	481.00
IUUC-Mpo-057417	Magnaporthe poae	43.84	1.00e-140	492.00
IUUC-Mtr-057849	Medicago truncatula	39.84	3.00e-98	352.00
IUUC-Mla-058870	Melampsora laricipopulina	45.04	6.00e-112	397.00
IUUC-Mga-059580	Meleagris gallopavo	32.82	7.00e-39	154.00
IUUC-Mvi-060507	Microbotryum violaceum	38.10	3.00e-122	432.00
IUUC-Mmr-060816	Microcebus murinus	37.85	8.00e-96	344.00
IUUC-Mdo-062866	Monodelphis domestica	33.49	1.00e-69	257.00
IUUC-Mmu-063906	Mus musculus	37.37	8.00e-94	337.00
IUUC-Mac-064675	Musa acuminata	37.85	5.00e-91	327.00
IUUC-Mpu-066199	Mustela putorius furo	37.58	4.00e-95	342.00
IUUC-Mlu-067110	Myotis lucifugus	37.65	2.00e-95	342.00
IUUC-Nfi-068482	Neosartorya fischeri	43.00	6.00e-144	503.00
IUUC-Ncr-068906	Neurospora crassa	43.46	2.00e-139	488.00
IUUC-Nle-069410	Nomascus leucogenys	37.58	4.00e-95	342.00
IUUC-Opr-070401	Ochotona princeps	41.75	4.00e-43	169.00
IUUC-Ont-072100	Oreochromis niloticus	38.87	2.00e-99	356.00
IUUC-Oan-073121	Ornithorhynchus anatinus	37.85	5.00e-96	345.00
IUUC-Ocu-074623	Oryctolagus cuniculus	37.58	2.00e-94	340.00
IUUC-Oba-075380	Oryza barthii	36.61	3.00e-87	315.00
IUUC-Obr-076915	Oryza brachyantha	36.82	3.00e-92	332.00
IUUC-Ogl-077055	Oryza glaberrima	37.02	3.00e-91	328.00
IUUC-Ogu-078892	Oryza glumaepatula	36.61	3.00e-87	315.00
IUUC-Oin-079256	Oryza indica	36.59	3.00e-89	322.00
IUUC-Olo-080343	Oryza longistaminata	36.59	2.00e-89	322.00
IUUC-Ome-081422	Oryza meridionalis	36.59	3.00e-89	322.00
IUUC-Oni-083047	Oryza nivara	36.81	8.00e-88	317.00
IUUC-Opu-083574	Oryza punctata	35.17	6.00e-81	295.00
IUUC-Oru-084439	Oryza rufipogon	36.61	2.00e-87	315.00
IUUC-Osa-085972	Oryza sativa	37.02	6.00e-91	326.00
IUUC-Ola-087173	Oryzias latipes	39.57	1.00e-99	357.00
IUUC-Olu-087871	Ostreococcus lucimarinus	35.74	6.00e-84	302.00
IUUC-Oga-087908	Otolemur garnettii	37.37	3.00e-94	339.00
IUUC-Oar-090277	Ovis aries	37.58	3.00e-95	342.00
IUUC-Ptr-091543	Pan troglodytes	37.58	4.00e-95	342.00
IUUC-Pan-092243	Papio anubis	37.58	5.00e-95	341.00
IUUC-Psi-093150	Pelodiscus sinensis	37.98	2.00e-96	346.00
IUUC-Pno-094891	Phaeosphaeria nodorum	42.55	1.00e-139	489.00
IUUC-Ppa-095181	Physcomitrella patens	38.57	4.00e-89	320.00
IUUC-Pfo-096267	Poecilia formosa	39.52	2.00e-98	353.00
IUUC-Pab-098072	Pongo abelii	37.58	4.00e-95	341.00
IUUC-Pop-099190	Populus trichocarpa	37.57	5.00e-94	338.00
IUUC-Pca-100311	Procavia capensis	37.78	2.00e-95	343.00
IUUC-Ppe-101284	Prunus persica	38.70	3.00e-95	342.00
IUUC-Pva-102215	Pteropus vampyrus	33.87	2.00e-79	290.00
IUUC-Pgr-103694	Puccinia graminis	45.55	4.00e-113	401.00
IUUC-Ptt-103916	Puccinia triticina	44.10	6.00e-107	380.00
IUUC-Pte-104346	Pyrenophora teres	42.60	3.00e-138	484.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	42.60	6.00e-138	483.00
IUUC-Rno-105315	Rattus norvegicus	37.58	9.00e-95	340.00
IUUC-Sce-106273	Saccharomyces cerevisiae	34.05	7.00e-105	373.00
IUUC-Sha-106835	Sarcophilus harrisii	37.85	2.00e-96	346.00
IUUC-Spo-108081	Schizosaccharomyces pombe	46.21	0.00e+00	1105.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	49.80	4.00e-139	488.00
IUUC-Smo-109590	Selaginella moellendorffii	37.43	1.00e-92	333.00
IUUC-Sit-109757	Setaria italica	38.22	9.00e-94	337.00
IUUC-Sly-111557	Solanum lycopersicum	39.33	4.00e-96	345.00
IUUC-Stu-112896	Solanum tuberosum	38.94	5.00e-87	313.00
IUUC-Sar-113224	Sorex araneus	37.57	4.00e-67	249.00
IUUC-Sbi-114313	Sorghum bicolor	38.27	6.00e-96	344.00
IUUC-Sre-114993	Sporisorium reilianum	42.71	3.00e-118	419.00
IUUC-Ssc-115535	Sus scrofa	35.89	6.00e-81	294.00
IUUC-Tgu-117167	Taeniopygia guttata	39.15	3.00e-36	146.00
IUUC-Tru-118669	Takifugu rubripes	39.19	3.00e-98	352.00
IUUC-Tsy-119373	Tarsius syrichta	29.67	6.00e-54	205.00
IUUC-Tni-120049	Tetraodon nigroviridis	35.79	1.00e-75	275.00
IUUC-Tca-121779	Theobroma cacao	39.42	4.00e-96	345.00
IUUC-Tre-122195	Trichoderma reesei	40.54	4.00e-136	478.00
IUUC-Tvi-122650	Trichoderma virens	42.28	2.00e-136	479.00
IUUC-Tae-123580	Triticum aestivum	38.06	7.00e-95	339.00
IUUC-Tur-126295	Triticum urartu	38.19	4.00e-96	345.00
IUUC-Tme-126964	Tuber melanosporum	49.90	6.00e-139	487.00
IUUC-Tbe-128149	Tupaia belangeri	28.38	1.00e-52	201.00
IUUC-Ttr-128165	Tursiops truncatus	37.58	4.00e-95	342.00
IUUC-Uma-129365	Ustilago maydis	43.51	3.00e-106	379.00
IUUC-Vda-129725	Verticillium dahliae	49.69	4.00e-140	491.00
IUUC-Vpa-130678	Vicugna pacos	37.58	5.00e-95	341.00
IUUC-Vvi-131539	Vitis vinifera	38.62	2.00e-95	342.00
IUUC-Xtr-132636	Xenopus tropicalis	37.63	7.00e-95	340.00
IUUC-Xma-133458	Xiphophorus maculatus	39.52	1.00e-98	353.00
IUUC-Yli-134481	Yarrowia lipolytica	41.54	7.00e-125	440.00
IUUC-Zma-135782	Zea mays	38.37	9.00e-95	340.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence