iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050147

Ensembl Protein ID

ENSLACP00000020214.1

UniProt Accession

H3BE93; H3BE93_LATCH

Genbank Protein ID

ENSLACP00000020214

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01039729

Gene Name

HERC4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000017766.1	ENSLACT00000020354.1	ENSLACP00000020214.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.10e-48	163.6	725	908

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           d kk l+v fvgEe++d+gGv +ef+ l+++el +p++g+f+y e+++  ++ +++      e  +lF+++G+++g+a+++  ++dlp+
   Q: 725  DYKKPLKVIFVGEEAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEESRLIWFSDQTF-----EDSDLFHLIGVVCGLAIYNLTIVDLPF 808
           78999**********************************************988866.....689************************ PP
   S: 93   sksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyr 181
           + ++yk+ll+kk +l+dl+e++p++ +sl++++++ e++iee+ ++l+f+v+ e++g t+++eL+p+G+ni Vt++N++e+v+++v+y 
   Q: 809  PLALYKKLLKKKPTLDDLKELKPDVGRSLQQLLDYPEDNIEEI-FCLNFTVTVENFGATEVRELVPNGANIAVTEKNRQEFVDAYVDYV 896
           ******************************************9.********************************************* PP
   S: 182  lkegikeqveaf 193
           + ++++  ++af
   Q: 897  FSTSVAPLFDAF 908
           ******999998 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MLCWGNASFG QLGLGGIDEE VVLEPRNCEF FQSKRIHDIG CGRRHTVFVP DDGTVYTCGC 60
NDLGQLGHEK ARKKPEQVGA LDAQTVVAVS CGEAHTLALN DKGQVFAWGL STDGQLGLPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGATCGGGCA GGGTTCATAC GTCACATCCT GTGTGAGGCG TTTGGAATGG GTCAGTTCTA 60
GAAACATTTA GATGATCTGG AAAGAACTTG GTGAAGTTTA GAATTCCGAG GTTAGAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001666	Ailuropoda melanoleuca	80.24	0.00e+00	1417.00
IUUC-Apl-003295	Anas platyrhynchos	80.48	0.00e+00	1464.00
IUUC-Aca-004336	Anolis carolinensis	80.02	0.00e+00	1449.00
IUUC-Ame-010768	Astyanax mexicanus	70.70	0.00e+00	1296.00
IUUC-Bta-013279	Bos taurus	80.35	0.00e+00	1420.00
IUUC-Cja-019023	Callithrix jacchus	80.68	0.00e+00	1425.00
IUUC-Cfa-021074	Canis familiaris	80.13	0.00e+00	1416.00
IUUC-Cpo-021461	Cavia porcellus	78.65	0.00e+00	1382.00
IUUC-Cre-023014	Chlamydomonas reinhardtii	38.63	4.00e-51	195.00
IUUC-Csa-024261	Chlorocebus sabaeus	80.68	0.00e+00	1425.00
IUUC-Cho-024513	Choloepus hoffmanni	63.29	0.00e+00	710.00
IUUC-Dre-028829	Danio rerio	73.22	0.00e+00	1300.00
IUUC-Dno-029445	Dasypus novemcinctus	80.64	0.00e+00	1111.00
IUUC-Ete-033072	Echinops telfairi	71.37	0.00e+00	1211.00
IUUC-Eca-033317	Equus caballus	79.48	0.00e+00	1400.00
IUUC-Fca-035682	Felis catus	81.06	0.00e+00	1425.00
IUUC-Fal-036969	Ficedula albicollis	80.46	0.00e+00	1464.00
IUUC-Gmo-038671	Gadus morhua	71.09	0.00e+00	1291.00
IUUC-Gga-041174	Gallus gallus	80.68	0.00e+00	1467.00
IUUC-Gac-042600	Gasterosteus aculeatus	70.98	0.00e+00	1244.00
IUUC-Gma-043616	Glycine max	36.66	7.00e-50	191.00
IUUC-Ggo-044589	Gorilla gorilla	80.79	0.00e+00	1448.00
IUUC-Hsa-046772	Homo sapiens	80.57	0.00e+00	1444.00
IUUC-Loc-052684	Lepisosteus oculatus	77.92	0.00e+00	1415.00
IUUC-Laf-053844	Loxodonta africana	80.35	0.00e+00	1420.00
IUUC-Mcc-055531	Macaca mulatta	78.62	0.00e+00	1411.00
IUUC-Mga-060151	Meleagris gallopavo	80.61	0.00e+00	1428.00
IUUC-Mmr-060954	Microcebus murinus	80.57	0.00e+00	1422.00
IUUC-Mdo-062246	Monodelphis domestica	79.95	0.00e+00	1305.00
IUUC-Mmu-063369	Mus musculus	80.40	0.00e+00	1437.00
IUUC-Mpu-065936	Mustela putorius furo	80.14	0.00e+00	1282.00
IUUC-Mlu-067326	Myotis lucifugus	79.69	0.00e+00	1415.00
IUUC-Nle-069453	Nomascus leucogenys	81.17	0.00e+00	1427.00
IUUC-Ont-071720	Oreochromis niloticus	73.46	0.00e+00	1316.00
IUUC-Oan-073464	Ornithorhynchus anatinus	80.86	0.00e+00	1322.00
IUUC-Ocu-074207	Oryctolagus cuniculus	77.84	0.00e+00	1272.00
IUUC-Ola-086762	Oryzias latipes	71.05	0.00e+00	1242.00
IUUC-Oga-088435	Otolemur garnettii	80.57	0.00e+00	1422.00
IUUC-Oar-089233	Ovis aries	80.46	0.00e+00	1421.00
IUUC-Ptr-091368	Pan troglodytes	80.79	0.00e+00	1447.00
IUUC-Pan-092300	Papio anubis	80.68	0.00e+00	1425.00
IUUC-Psi-093406	Pelodiscus sinensis	80.79	0.00e+00	1469.00
IUUC-Pma-094113	Petromyzon marinus	68.07	0.00e+00	892.00
IUUC-Pfo-097021	Poecilia formosa	72.14	0.00e+00	1329.00
IUUC-Pab-098327	Pongo abelii	80.57	0.00e+00	1444.00
IUUC-Pca-101075	Procavia capensis	77.34	0.00e+00	684.00
IUUC-Pva-102909	Pteropus vampyrus	72.93	0.00e+00	1231.00
IUUC-Rno-105457	Rattus norvegicus	79.91	0.00e+00	1431.00
IUUC-Sha-106632	Sarcophilus harrisii	80.18	0.00e+00	1450.00
IUUC-Sar-113679	Sorex araneus	73.26	0.00e+00	951.00
IUUC-Tgu-116849	Taeniopygia guttata	76.42	0.00e+00	1369.00
IUUC-Tru-118206	Takifugu rubripes	70.75	0.00e+00	1239.00
IUUC-Tsy-119521	Tarsius syrichta	69.76	0.00e+00	1165.00
IUUC-Tni-120233	Tetraodon nigroviridis	70.47	0.00e+00	1204.00
IUUC-Tbe-127941	Tupaia belangeri	67.65	0.00e+00	965.00
IUUC-Ttr-128926	Tursiops truncatus	78.43	0.00e+00	942.00
IUUC-Vpa-130448	Vicugna pacos	79.69	0.00e+00	1407.00
IUUC-Xtr-132719	Xenopus tropicalis	66.70	0.00e+00	1097.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence