iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-116022

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU942393

Gene Name

USP36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000017165.2	ENSSSCT00000018689.2	ENSSSCP00000018188.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.20e-80	269.4	129	427

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NS++QcL+ +p+l+++ll+ ++++ +++      + ++l+ +q+ + +   ++ +a++p ++++ l+k+a++f+  +q
   Q: 129  GLHNLGNTCFLNSTVQCLTYTPPLANYLLSrEHTRGCHQ-----GSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLRKIARHFRFGNQ 212
           9*****************************555566654.....46799999999999999**************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  ls  a+ + +++ ++l++++F+g l+s++kc  c++vs +++p ld+ l++++
   Q: 213  EDAHEFLRYTIDAMQKAC------------------LSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQ 283
           ******************..................55566778999****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                  ++  +Le f+k++ l gen+y c kckkk+ a+k++++++ ++vL+l LkRf    ++ s  ki+k+v +p+ L+++p++++
   Q: 284  AA-----NIVRALELFVKPDVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRF----ANFSGGKITKEVGYPEFLNIRPYMSQ 363
           **.....9***************************************************....668899******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds V++++ + vl+   ++aYvlfY 
   Q: 364  SNGE---PVLYGLYAVLVHSGySCHAGHYYCYVKASSGQWYQMNDSLVHASNIKVVLN---QQAYVLFYL 427
           6654...9**************************************************...********6 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MPIVDKLKEA LKPGRRDSAD DGELGRLLAS SAKKVLLQKL EFEPASKSFS YQLESLKSKY 60
VLLNPRPEGA GCPKSGGEPP GAGSGCHRSW GGELASDGDG DGVPAPQKVL FPGERLSLRW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCATAG TGGACAAGCT GAAGGAAGCC CTCAAGCCGG GCCGCAGGGA CTCGGCTGAC 60
GATGGGGAGC TGGGGAGGCT TCTGGCCTCC TCCGCCAAGA AGGTCCTTCT GCAGAAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:1903146--P:regulation of mitophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000401	Aegilops tauschii	39.08	2.00e-68	253.00
IUUC-Aml-002092	Ailuropoda melanoleuca	71.93	0.00e+00	1254.00
IUUC-Atr-003102	Amborella trichopoda	41.03	3.00e-86	313.00
IUUC-Apl-003459	Anas platyrhynchos	61.82	2.00e-131	463.00
IUUC-Aca-005360	Anolis carolinensis	60.98	0.00e+00	851.00
IUUC-Aly-006389	Arabidopsis lyrata	43.31	8.00e-77	281.00
IUUC-Ath-006710	Arabidopsis thaliana	43.31	1.00e-76	281.00
IUUC-Ago-007836	Ashbya gossypii	26.90	2.00e-31	130.00
IUUC-Ame-011358	Astyanax mexicanus	73.25	7.00e-158	551.00
IUUC-Bta-013047	Bos taurus	76.24	0.00e+00	1368.00
IUUC-Bdi-014036	Brachypodium distachyon	46.20	4.00e-86	312.00
IUUC-Bol-015086	Brassica oleracea	44.48	7.00e-82	298.00
IUUC-Bra-016634	Brassica rapa	39.10	6.00e-83	301.00
IUUC-Cja-019203	Callithrix jacchus	67.19	0.00e+00	1159.00
IUUC-Cfa-020586	Canis familiaris	72.02	0.00e+00	1297.00
IUUC-Cpo-021804	Cavia porcellus	61.69	0.00e+00	1120.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	46.85	2.00e-52	198.00
IUUC-Csa-023137	Chlorocebus sabaeus	68.95	0.00e+00	1232.00
IUUC-Cho-024575	Choloepus hoffmanni	58.31	1.00e-107	384.00
IUUC-Cin-025230	Ciona intestinalis	52.38	3.00e-97	348.00
IUUC-Cne-027049	Cryptococcus neoformans	34.37	9.00e-38	151.00
IUUC-Cme-027339	Cyanidioschyzon merolae	38.26	1.00e-59	223.00
IUUC-Dre-028587	Danio rerio	73.37	0.00e+00	784.00
IUUC-Dno-029149	Dasypus novemcinctus	64.05	0.00e+00	1159.00
IUUC-Dor-030836	Dipodomys ordii	63.18	0.00e+00	859.00
IUUC-Dme-032119	Drosophila melanogaster	33.71	1.00e-70	261.00
IUUC-Ete-032567	Echinops telfairi	65.07	0.00e+00	769.00
IUUC-Eca-033600	Equus caballus	74.05	0.00e+00	1325.00
IUUC-Eeu-035206	Erinaceus europaeus	58.20	1.00e-132	467.00
IUUC-Fca-035792	Felis catus	71.12	5.00e-154	538.00
IUUC-Fal-036852	Ficedula albicollis	69.68	7.00e-160	557.00
IUUC-Gmo-039033	Gadus morhua	71.24	0.00e+00	773.00
IUUC-Gga-040664	Gallus gallus	74.90	0.00e+00	731.00
IUUC-Gac-042176	Gasterosteus aculeatus	61.32	0.00e+00	781.00
IUUC-Gma-044075	Glycine max	48.53	1.00e-83	304.00
IUUC-Ggo-045437	Gorilla gorilla	68.51	0.00e+00	1182.00
IUUC-Hsa-046863	Homo sapiens	68.77	0.00e+00	1190.00
IUUC-Hvu-047620	Hordeum vulgare	39.76	5.00e-69	256.00
IUUC-Itr-048655	Ictidomys tridecemlineatus	68.18	0.00e+00	1027.00
IUUC-Lch-050120	Latimeria chalumnae	59.47	0.00e+00	721.00
IUUC-Lpe-051574	Leersia perrieri	43.24	1.00e-79	290.00
IUUC-Loc-052796	Lepisosteus oculatus	77.35	0.00e+00	747.00
IUUC-Laf-054243	Loxodonta africana	66.14	0.00e+00	1156.00
IUUC-Mcc-055762	Macaca mulatta	68.60	0.00e+00	1207.00
IUUC-Meu-056697	Macropus eugenii	60.16	0.00e+00	1102.00
IUUC-Mtr-058537	Medicago truncatula	48.53	2.00e-83	303.00
IUUC-Mla-059049	Melampsora laricipopulina	42.50	6.00e-59	222.00
IUUC-Mga-059359	Meleagris gallopavo	78.84	3.00e-155	541.00
IUUC-Mvi-060547	Microbotryum violaceum	44.92	8.00e-78	284.00
IUUC-Mmr-060966	Microcebus murinus	69.36	0.00e+00	1176.00
IUUC-Mdo-062733	Monodelphis domestica	67.35	0.00e+00	951.00
IUUC-Mmu-064331	Mus musculus	63.76	0.00e+00	1135.00
IUUC-Mac-064815	Musa acuminata	46.36	1.00e-86	313.00
IUUC-Mpu-065759	Mustela putorius furo	72.23	0.00e+00	1229.00
IUUC-Mlu-067371	Myotis lucifugus	67.88	0.00e+00	1194.00
IUUC-Nle-070087	Nomascus leucogenys	67.84	0.00e+00	1159.00
IUUC-Opr-070729	Ochotona princeps	63.44	0.00e+00	892.00
IUUC-Ont-071346	Oreochromis niloticus	73.85	0.00e+00	788.00
IUUC-Oan-072931	Ornithorhynchus anatinus	65.13	0.00e+00	820.00
IUUC-Ocu-074823	Oryctolagus cuniculus	59.82	0.00e+00	986.00
IUUC-Oba-075866	Oryza barthii	45.71	2.00e-84	306.00
IUUC-Obr-076408	Oryza brachyantha	45.25	1.00e-84	307.00
IUUC-Ogl-077559	Oryza glaberrima	46.20	3.00e-85	310.00
IUUC-Ogu-078064	Oryza glumaepatula	45.89	4.00e-85	309.00
IUUC-Oin-079471	Oryza indica	46.20	2.00e-85	310.00
IUUC-Olo-080231	Oryza longistaminata	43.99	3.00e-77	283.00
IUUC-Ome-081746	Oryza meridionalis	46.41	7.00e-84	305.00
IUUC-Oni-082339	Oryza nivara	45.89	4.00e-85	309.00
IUUC-Opu-083194	Oryza punctata	45.89	2.00e-84	308.00
IUUC-Oru-085083	Oryza rufipogon	45.89	3.00e-85	309.00
IUUC-Osa-085395	Oryza sativa	46.20	1.00e-85	311.00
IUUC-Ola-087255	Oryzias latipes	72.44	0.00e+00	787.00
IUUC-Olu-087773	Ostreococcus lucimarinus	45.57	9.00e-72	263.00
IUUC-Oga-088818	Otolemur garnettii	67.41	0.00e+00	1031.00
IUUC-Oar-089410	Ovis aries	75.27	0.00e+00	1353.00
IUUC-Ptr-090680	Pan troglodytes	69.84	0.00e+00	1023.00
IUUC-Pan-092482	Papio anubis	68.51	0.00e+00	1235.00
IUUC-Psi-093277	Pelodiscus sinensis	71.77	7.00e-159	555.00
IUUC-Pma-094591	Petromyzon marinus	58.01	2.00e-49	187.00
IUUC-Ppa-095853	Physcomitrella patens	48.09	4.00e-92	332.00
IUUC-Pfo-096807	Poecilia formosa	76.33	0.00e+00	797.00
IUUC-Pab-098724	Pongo abelii	68.68	0.00e+00	1219.00
IUUC-Pop-099693	Populus trichocarpa	46.98	8.00e-84	305.00
IUUC-Pca-100117	Procavia capensis	72.05	1.00e-142	501.00
IUUC-Ppe-101678	Prunus persica	45.71	2.00e-81	296.00
IUUC-Pva-102883	Pteropus vampyrus	62.13	0.00e+00	958.00
IUUC-Pgr-103270	Puccinia graminis	44.69	1.00e-66	247.00
IUUC-Ptt-103887	Puccinia triticina	44.06	3.00e-66	246.00
IUUC-Rno-105340	Rattus norvegicus	57.87	0.00e+00	956.00
IUUC-Sha-107019	Sarcophilus harrisii	59.45	0.00e+00	1085.00
IUUC-Sja-107805	Schizosaccharomyces japonicus	43.99	1.00e-76	280.00
IUUC-Spo-108119	Schizosaccharomyces pombe	43.29	1.00e-82	300.00
IUUC-Smo-108763	Selaginella moellendorffii	47.40	1.00e-81	295.00
IUUC-Sit-110536	Setaria italica	46.20	2.00e-80	293.00
IUUC-Sly-111722	Solanum lycopersicum	39.59	2.00e-78	287.00
IUUC-Stu-112912	Solanum tuberosum	39.56	4.00e-79	289.00
IUUC-Sar-113340	Sorex araneus	71.12	4.00e-154	538.00
IUUC-Sbi-114477	Sorghum bicolor	46.20	2.00e-87	316.00
IUUC-Sre-114924	Sporisorium reilianum	41.07	2.00e-67	250.00
IUUC-Tgu-116976	Taeniopygia guttata	69.48	9.00e-157	546.00
IUUC-Tru-118391	Takifugu rubripes	76.33	0.00e+00	799.00
IUUC-Tsy-118974	Tarsius syrichta	71.43	3.00e-155	542.00
IUUC-Tni-120064	Tetraodon nigroviridis	76.95	0.00e+00	793.00
IUUC-Tca-120936	Theobroma cacao	42.53	1.00e-83	304.00
IUUC-Tae-125259	Triticum aestivum	48.26	9.00e-89	321.00
IUUC-Tur-126014	Triticum urartu	47.39	4.00e-84	306.00
IUUC-Tbe-127377	Tupaia belangeri	57.50	0.00e+00	706.00
IUUC-Ttr-129259	Tursiops truncatus	81.86	0.00e+00	749.00
IUUC-Uma-129416	Ustilago maydis	42.94	2.00e-68	253.00
IUUC-Vpa-130568	Vicugna pacos	67.52	1.00e-44	175.00
IUUC-Vvi-131535	Vitis vinifera	39.68	2.00e-86	313.00
IUUC-Xtr-132944	Xenopus tropicalis	75.70	0.00e+00	667.00
IUUC-Xma-133735	Xiphophorus maculatus	76.33	0.00e+00	799.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence