iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108274

UUCD1 version

UUC-ScP-00145

Ensembl Protein ID

SPAC17C9.01c.1:pep

UniProt Accession

P10505; Q9US21; APC3_SCHPO

Genbank Protein ID

CAA30532.1; CAA97347.1

Protein Name

Anaphase-promoting complex subunit 3; 20S cyclosome/APC complex protein apc3; Nuclear alteration protein 2; Nuclear scaffold-like protein p76

Genbank Nucleotide ID

X07693; CU329670

Gene Name

nuc2; apc3; SPAC17C9.01c; SPAC1851.01

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC17C9.01c	SPAC17C9.01c.1	SPAC17C9.01c.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	39.19	4.00e-73	270.00	IUUC-Sce-106187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Interacts with spindle apparatus, chromosomes, or nuclear envelope, and interconnect nuclear and cytoskeletal functions in mitosis, so the elongation of the spindle in anaphase is blocked.

Protein Sequence
(Fasta)

MTDRLKCLIW YCIDNQNYDN SIFYSERLHA IEDSNESLYL LAYSHFLNLD YNIVYDLLDR 60
VISHVPCTYL FARTSLILGR YKQGISAVEA CRSNWRSIQP NINDSISSRG HPDASCMLDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCACATGTT TTTGTTGACA TTAACTCCCA TCGTTTCCAA AACTTTAATA GATTTGTCAT 60
GACAGATCGA TTGAAATGTT TAATATGGTA TTGCATTGAT AATCAGAATT ATGATAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR007330--MIT
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001440--TPR_1
IPR019734--TPR_repeat

PROSITE

PS50005--TPR
PS50293--TPR_REGION

Pfam

PF00515--TPR_1
PF13181--TPR_8

SMART

SM00028--TPR

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0032153--C:cell division site
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0051301--P:cell division
GO:0071851--P:mitotic G1 cell cycle arrest in response to nitrogen starvation
GO:0000070--P:mitotic sister chromatid segregation

KEGG

spo:SPAC17C9.01c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000478	Aegilops tauschii	41.61	2.00e-69	254.00
IUUC-Aml-002123	Ailuropoda melanoleuca	46.48	2.00e-84	304.00
IUUC-Atr-002921	Amborella trichopoda	41.72	2.00e-71	261.00
IUUC-Apl-003652	Anas platyrhynchos	46.48	1.00e-84	305.00
IUUC-Aca-004797	Anolis carolinensis	45.99	5.00e-83	300.00
IUUC-Aly-006146	Arabidopsis lyrata	40.74	1.00e-65	242.00
IUUC-Ath-007523	Arabidopsis thaliana	40.37	7.00e-76	276.00
IUUC-Ago-007939	Ashbya gossypii	45.42	4.00e-73	267.00
IUUC-Acl-008169	Aspergillus clavatus	51.25	6.00e-97	346.00
IUUC-Afl-008631	Aspergillus flavus	49.38	8.00e-90	322.00
IUUC-Afu-008990	Aspergillus fumigatus	50.94	7.00e-97	346.00
IUUC-Ani-009208	Aspergillus nidulans	46.11	2.00e-46	178.00
IUUC-Ang-009561	Aspergillus niger	49.85	2.00e-96	344.00
IUUC-Aor-009958	Aspergillus oryzae	49.38	2.00e-89	321.00
IUUC-Ate-010597	Aspergillus terreus	44.17	1.00e-97	348.00
IUUC-Ame-010734	Astyanax mexicanus	46.15	2.00e-62	230.00
IUUC-Bgr-012282	Blumeria graminis	50.15	2.00e-93	335.00
IUUC-Bta-013499	Bos taurus	46.48	3.00e-84	304.00
IUUC-Bci-013946	Botrytis cinerea	45.38	6.00e-98	350.00
IUUC-Bdi-014213	Brachypodium distachyon	42.26	2.00e-70	258.00
IUUC-Bol-016307	Brassica oleracea	40.68	6.00e-76	276.00
IUUC-Bra-017042	Brassica rapa	40.37	4.00e-76	277.00
IUUC-Cel-018481	Caenorhabditis elegans	38.08	9.00e-55	206.00
IUUC-Cja-019393	Callithrix jacchus	46.48	2.00e-84	305.00
IUUC-Cfa-020221	Canis familiaris	46.48	2.00e-84	304.00
IUUC-Cpo-021792	Cavia porcellus	46.79	2.00e-84	305.00
IUUC-Csa-023091	Chlorocebus sabaeus	46.48	2.00e-84	304.00
IUUC-Cin-025231	Ciona intestinalis	39.25	7.00e-67	246.00
IUUC-Csv-025983	Ciona savignyi	39.56	4.00e-72	264.00
IUUC-Cgl-026436	Colletotrichum gloeosporioides	45.74	7.00e-86	310.00
IUUC-Cne-026779	Cryptococcus neoformans	40.13	4.00e-68	250.00
IUUC-Cme-027126	Cyanidioschyzon merolae	33.23	1.00e-45	175.00
IUUC-Dre-028038	Danio rerio	43.42	6.00e-83	300.00
IUUC-Dno-029681	Dasypus novemcinctus	46.48	2.00e-84	305.00
IUUC-Dor-030742	Dipodomys ordii	37.41	4.00e-42	164.00
IUUC-Dse-031468	Dothistroma septosporum	45.65	3.00e-77	281.00
IUUC-Dme-031900	Drosophila melanogaster	37.16	2.00e-59	222.00
IUUC-Ete-032396	Echinops telfairi	41.27	2.00e-72	265.00
IUUC-Eca-034414	Equus caballus	46.48	3.00e-84	304.00
IUUC-Eeu-034864	Erinaceus europaeus	41.90	4.00e-71	260.00
IUUC-Fca-036459	Felis catus	46.48	7.00e-84	303.00
IUUC-Fox-037700	Fusarium oxysporum	51.03	2.00e-86	310.00
IUUC-Fso-038112	Fusarium solani	48.60	8.00e-93	333.00
IUUC-Gmo-038876	Gadus morhua	43.79	1.00e-77	282.00
IUUC-Ggr-039822	Gaeumannomyces graminis	48.56	7.00e-87	313.00
IUUC-Gga-040585	Gallus gallus	46.48	1.00e-84	305.00
IUUC-Gac-042126	Gasterosteus aculeatus	45.03	5.00e-85	306.00
IUUC-Gma-044263	Glycine max	40.67	4.00e-73	267.00
IUUC-Ggo-045272	Gorilla gorilla	30.24	9.00e-71	259.00
IUUC-Hsa-045682	Homo sapiens	45.45	2.00e-84	305.00
IUUC-Hvu-047421	Hordeum vulgare	41.90	4.00e-56	209.00
IUUC-Itr-048133	Ictidomys tridecemlineatus	46.48	2.00e-84	304.00
IUUC-Kpa-049367	Komagataella pastoris	48.61	2.00e-91	328.00
IUUC-Lch-049755	Latimeria chalumnae	46.18	2.00e-84	304.00
IUUC-Lpe-051689	Leersia perrieri	39.08	6.00e-68	249.00
IUUC-Loc-052907	Lepisosteus oculatus	45.79	6.00e-83	300.00
IUUC-Lma-053272	Leptosphaeria maculans	45.23	3.00e-82	298.00
IUUC-Laf-054312	Loxodonta africana	46.18	5.00e-84	303.00
IUUC-Mcc-055312	Macaca mulatta	46.48	2.00e-84	304.00
IUUC-Meu-056290	Macropus eugenii	39.76	1.00e-64	239.00
IUUC-Mor-057118	Magnaporthe oryzae	48.24	9.00e-87	312.00
IUUC-Mpo-057620	Magnaporthe poae	48.56	3.00e-87	314.00
IUUC-Mtr-058302	Medicago truncatula	39.14	2.00e-70	258.00
IUUC-Mla-058835	Melampsora laricipopulina	35.54	2.00e-54	204.00
IUUC-Mga-060010	Meleagris gallopavo	46.48	8.00e-85	306.00
IUUC-Mvi-060340	Microbotryum violaceum	39.81	2.00e-69	255.00
IUUC-Mmr-060610	Microcebus murinus	46.79	8.00e-80	289.00
IUUC-Mdo-062216	Monodelphis domestica	46.18	9.00e-84	302.00
IUUC-Mmu-063476	Mus musculus	46.18	7.00e-84	303.00
IUUC-Mac-065409	Musa acuminata	39.63	4.00e-71	260.00
IUUC-Mpu-066213	Mustela putorius furo	46.48	2.00e-84	304.00
IUUC-Mlu-067540	Myotis lucifugus	46.48	2.00e-84	304.00
IUUC-Nfi-068437	Neosartorya fischeri	50.94	3.00e-97	347.00
IUUC-Ncr-068882	Neurospora crassa	46.97	1.00e-89	322.00
IUUC-Nle-068976	Nomascus leucogenys	46.48	3.00e-84	304.00
IUUC-Opr-071171	Ochotona princeps	42.81	3.00e-72	265.00
IUUC-Ont-071295	Oreochromis niloticus	45.24	1.00e-84	305.00
IUUC-Oan-072896	Ornithorhynchus anatinus	47.90	3.00e-77	280.00
IUUC-Ocu-074828	Oryctolagus cuniculus	46.48	2.00e-84	305.00
IUUC-Oba-075176	Oryza barthii	38.23	1.00e-60	225.00
IUUC-Obr-076622	Oryza brachyantha	42.58	1.00e-71	262.00
IUUC-Ogu-078158	Oryza glumaepatula	41.28	1.00e-69	255.00
IUUC-Oin-079840	Oryza indica	42.81	6.00e-75	273.00
IUUC-Olo-080632	Oryza longistaminata	43.00	5.00e-71	259.00
IUUC-Ome-081193	Oryza meridionalis	42.81	8.00e-75	273.00
IUUC-Oni-082335	Oryza nivara	38.23	1.00e-60	225.00
IUUC-Opu-083857	Oryza punctata	43.21	1.00e-66	245.00
IUUC-Oru-085165	Oryza rufipogon	37.92	5.00e-60	223.00
IUUC-Osa-085529	Oryza sativa	42.81	3.00e-74	269.00
IUUC-Olu-087803	Ostreococcus lucimarinus	39.84	4.00e-69	253.00
IUUC-Oga-088851	Otolemur garnettii	46.79	7.00e-85	306.00
IUUC-Oar-089794	Ovis aries	45.45	2.00e-84	305.00
IUUC-Ptr-091588	Pan troglodytes	46.48	3.00e-84	304.00
IUUC-Pan-092083	Papio anubis	46.48	4.00e-84	303.00
IUUC-Psi-093368	Pelodiscus sinensis	46.48	1.00e-84	306.00
IUUC-Pma-094306	Petromyzon marinus	44.51	1.00e-80	292.00
IUUC-Pno-094898	Phaeosphaeria nodorum	46.50	1.00e-86	311.00
IUUC-Ppa-095288	Physcomitrella patens	41.64	2.00e-70	258.00
IUUC-Pfo-097263	Poecilia formosa	40.63	1.00e-85	308.00
IUUC-Pab-097782	Pongo abelii	46.48	2.00e-84	304.00
IUUC-Pca-100771	Procavia capensis	38.72	4.00e-58	218.00
IUUC-Ppe-102042	Prunus persica	39.02	7.00e-72	263.00
IUUC-Pva-103207	Pteropus vampyrus	46.48	3.00e-84	304.00
IUUC-Pgr-103352	Puccinia graminis	38.54	2.00e-55	208.00
IUUC-Ptt-103992	Puccinia triticina	40.62	4.00e-30	124.00
IUUC-Pte-104138	Pyrenophora teres	43.95	7.00e-83	299.00
IUUC-Pyt-104652	Pyrenophora triticirepentis	43.95	6.00e-83	300.00
IUUC-Rno-105451	Rattus norvegicus	45.16	6.00e-84	303.00
IUUC-Sce-106187	Saccharomyces cerevisiae	39.19	3.00e-74	271.00
IUUC-Sha-107398	Sarcophilus harrisii	46.18	3.00e-83	301.00
IUUC-Sja-107984	Schizosaccharomyces japonicus	52.54	0.00e+00	665.00
IUUC-Smo-109678	Selaginella moellendorffii	42.55	2.00e-78	284.00
IUUC-Sit-110813	Setaria italica	42.58	4.00e-71	260.00
IUUC-Sly-111637	Solanum lycopersicum	39.21	3.00e-74	270.00
IUUC-Stu-112086	Solanum tuberosum	38.78	2.00e-69	254.00
IUUC-Sar-113214	Sorex araneus	46.48	3.00e-84	304.00
IUUC-Sre-114904	Sporisorium reilianum	35.51	5.00e-37	147.00
IUUC-Ssc-115692	Sus scrofa	50.23	2.00e-62	231.00
IUUC-Tgu-116466	Taeniopygia guttata	46.48	1.00e-84	305.00
IUUC-Tru-118417	Takifugu rubripes	40.10	6.00e-85	306.00
IUUC-Tsy-118796	Tarsius syrichta	46.18	9.00e-84	302.00
IUUC-Tni-120331	Tetraodon nigroviridis	45.71	2.00e-83	300.00
IUUC-Tca-121321	Theobroma cacao	40.80	5.00e-76	276.00
IUUC-Tre-122083	Trichoderma reesei	45.48	7.00e-88	316.00
IUUC-Tvi-122558	Trichoderma virens	47.27	1.00e-90	325.00
IUUC-Tae-125209	Triticum aestivum	41.94	4.00e-70	257.00
IUUC-Tur-126187	Triticum urartu	37.10	1.00e-53	202.00
IUUC-Tme-127012	Tuber melanosporum	46.65	4.00e-108	384.00
IUUC-Tbe-127774	Tupaia belangeri	39.46	9.00e-65	239.00
IUUC-Ttr-128605	Tursiops truncatus	41.90	4.00e-73	267.00
IUUC-Uma-129576	Ustilago maydis	35.48	2.00e-32	133.00
IUUC-Vda-129996	Verticillium dahliae	48.58	2.00e-70	256.00
IUUC-Vpa-130122	Vicugna pacos	46.48	2.00e-84	304.00
IUUC-Vvi-131580	Vitis vinifera	40.37	3.00e-73	267.00
IUUC-Xtr-131756	Xenopus tropicalis	46.18	3.00e-79	287.00
IUUC-Xma-133214	Xiphophorus maculatus	40.39	3.00e-85	307.00
IUUC-Yli-134473	Yarrowia lipolytica	50.16	6.00e-94	336.00
IUUC-Zma-135179	Zea mays	41.28	4.00e-73	267.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence