iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-043567

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM000853

Gene Name

LOC100805072; GLYMA_20G190900

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA20G33270	GLYMA20G33270.1	GLYMA20G33270.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-36	124.3	50	85
UBD/Beta-Prp	2.20e-76	258.5	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++ +l+vsG+dD +ikvW+++ +++
   Q: 50   HDGPVRGVHFhHSqPLFVSGGDDYKIKVWNYKLHRC 85
           99*********445****************876666 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           t +++++++++ + f+p++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh d++
   Q: 3    TKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDKFDEHDGPVRGVHFHHSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYI 96
           67889999************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......................... 166
           ++++f+ ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+ +hp+++l+vs+slD+tvr+Wd+                         
   Q: 97   RTVQFHHENPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCALFHPKEDLVVSASLDQTVRVWDIsslkrksaspaddilrlsqmntdlf 189
           *********************************.**************************************************7776666666 PP
   S: 167  ..ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
               + + + l+g h++ v++ sf+++ + +vs+++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ 
   Q: 190  ggVDAVVKYVLEG-HDRGVNWASFHPTLPLIVSAADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTG 282
           6333334444466.********************************777668****************************************** PP
   S: 257  lktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 283  IQTFRREHDRFWILAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ****************.6666655555.689999999988765 PP

Organism

Glycine max

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPK RPWILASLHS GVIQLWDYRM GTLIDKFDEH DGPVRGVHFH 60
HSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHENPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACAGGATAC CTATGAGTGT TATAAACTAT GTGGTATCCG TCTTTGATTA TATGGATAAA 60
AATAAATAAA TACAAAGTTT ATGCTAAATT ACTTTGAAGC CCAACAATAA AAAAGAGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

gmx:100805072

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001758	Ailuropoda melanoleuca	54.82	0.00e+00	1362.00
IUUC-Aca-005154	Anolis carolinensis	77.99	2.00e-95	341.00
IUUC-Bta-012524	Bos taurus	55.30	0.00e+00	1353.00
IUUC-Cfa-020675	Canis familiaris	54.49	0.00e+00	1335.00
IUUC-Cpo-021813	Cavia porcellus	55.30	0.00e+00	1372.00
IUUC-Csa-023523	Chlorocebus sabaeus	55.30	0.00e+00	1375.00
IUUC-Cho-024704	Choloepus hoffmanni	42.66	3.00e-177	615.00
IUUC-Csv-025864	Ciona savignyi	58.21	0.00e+00	996.00
IUUC-Cne-027053	Cryptococcus neoformans	51.46	0.00e+00	1190.00
IUUC-Dno-029303	Dasypus novemcinctus	55.54	0.00e+00	1379.00
IUUC-Fca-035739	Felis catus	54.55	0.00e+00	1335.00
IUUC-Fal-037263	Ficedula albicollis	51.47	0.00e+00	1215.00
IUUC-Gga-040590	Gallus gallus	54.98	0.00e+00	1365.00
IUUC-Ggo-045029	Gorilla gorilla	54.90	0.00e+00	1367.00
IUUC-Hsa-046078	Homo sapiens	54.90	0.00e+00	1366.00
IUUC-Loc-051867	Lepisosteus oculatus	50.64	0.00e+00	816.00
IUUC-Lma-053138	Leptosphaeria maculans	46.35	0.00e+00	1109.00
IUUC-Laf-053510	Loxodonta africana	55.83	0.00e+00	1377.00
IUUC-Mmr-061102	Microcebus murinus	54.74	0.00e+00	1352.00
IUUC-Mpu-066701	Mustela putorius furo	55.06	0.00e+00	1361.00
IUUC-Mlu-067392	Myotis lucifugus	55.21	0.00e+00	1351.00
IUUC-Oga-087991	Otolemur garnettii	52.06	0.00e+00	1268.00
IUUC-Oar-089590	Ovis aries	55.21	0.00e+00	1370.00
IUUC-Pab-098497	Pongo abelii	55.30	0.00e+00	1377.00
IUUC-Pva-102126	Pteropus vampyrus	52.65	0.00e+00	1291.00
IUUC-Ssc-115933	Sus scrofa	55.30	0.00e+00	1370.00
IUUC-Tgu-117109	Taeniopygia guttata	44.08	2.00e-113	402.00
IUUC-Tbe-127882	Tupaia belangeri	69.03	1.00e-127	451.00
IUUC-Ttr-128217	Tursiops truncatus	53.13	0.00e+00	1301.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence