iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000005670.3	ENSCINT00000035968.1	ENSCINP00000033135.1
ENSCING00000005670.3	ENSCINT00000011733.3	ENSCINP00000011733.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.90e-27	92.7	160	212

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFv 59
           ++kvq+ yd+  q+ +eL++ +Gd+++v   e  d++W++g    +++ G+fP+n v
   Q: 160  NFKVQAAYDFRRQEPGELEFCQGDIITVT--EWMDKNWWRG--SVNNCTGIFPSNHV 212
           689*************************7..99********..9***********97 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MESIAKYDFK ATAPDELSFR KSDILKVLNL EDDRNWCRAE IDGRMGLVPK NYIELKAHDW 60
YHGKISRVKA EQSLNKPHYP DGAFLIRESE SSPGDFSLSV KYGSAVQHFK VLRDGAGKYF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAGCACATT ATGCATATTG ACTGTGTCCG TACTGGGCAA TAGTGTTATA GTTACGACGT 60
TACAGCAATT GAACTACAAA TAACATATAA ACAATGGAAA GTATTGCAAA ATACGACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001345	Ailuropoda melanoleuca	60.11	1.00e-61	227.00
IUUC-Apl-003322	Anas platyrhynchos	60.75	2.00e-61	227.00
IUUC-Aca-005193	Anolis carolinensis	62.74	4.00e-74	269.00
IUUC-Ame-010929	Astyanax mexicanus	60.56	9.00e-73	264.00
IUUC-Bta-012932	Bos taurus	63.21	3.00e-74	269.00
IUUC-Cel-018665	Caenorhabditis elegans	54.72	1.00e-66	244.00
IUUC-Cja-019225	Callithrix jacchus	63.21	3.00e-74	269.00
IUUC-Cfa-020887	Canis familiaris	63.21	3.00e-74	269.00
IUUC-Cpo-022488	Cavia porcellus	63.21	3.00e-74	269.00
IUUC-Csa-023326	Chlorocebus sabaeus	63.21	3.00e-74	269.00
IUUC-Cho-024953	Choloepus hoffmanni	52.83	1.00e-53	201.00
IUUC-Csv-026210	Ciona savignyi	83.98	2.00e-117	412.00
IUUC-Dre-028403	Danio rerio	62.74	5.00e-74	268.00
IUUC-Dno-029187	Dasypus novemcinctus	61.97	7.00e-74	268.00
IUUC-Dor-030763	Dipodomys ordii	63.21	3.00e-74	269.00
IUUC-Dme-031741	Drosophila melanogaster	61.93	8.00e-75	271.00
IUUC-Ete-032354	Echinops telfairi	44.13	7.00e-43	165.00
IUUC-Eca-033222	Equus caballus	63.21	3.00e-74	269.00
IUUC-Eeu-034513	Erinaceus europaeus	69.00	2.00e-35	140.00
IUUC-Fca-036294	Felis catus	63.21	3.00e-74	269.00
IUUC-Fal-037130	Ficedula albicollis	63.21	3.00e-74	269.00
IUUC-Gmo-039546	Gadus morhua	62.74	9.00e-74	268.00
IUUC-Gga-041139	Gallus gallus	63.21	3.00e-74	269.00
IUUC-Gac-041968	Gasterosteus aculeatus	62.44	5.00e-74	268.00
IUUC-Ggo-044562	Gorilla gorilla	63.21	3.00e-74	269.00
IUUC-Hsa-046730	Homo sapiens	63.21	3.00e-74	269.00
IUUC-Itr-049025	Ictidomys tridecemlineatus	63.21	3.00e-74	269.00
IUUC-Lch-050230	Latimeria chalumnae	69.77	1.00e-48	185.00
IUUC-Loc-052723	Lepisosteus oculatus	62.91	5.00e-75	272.00
IUUC-Laf-053774	Loxodonta africana	64.62	2.00e-75	273.00
IUUC-Mcc-054603	Macaca mulatta	63.21	3.00e-74	269.00
IUUC-Meu-056173	Macropus eugenii	52.83	2.00e-56	210.00
IUUC-Mga-059950	Meleagris gallopavo	63.21	3.00e-74	269.00
IUUC-Mmr-060878	Microcebus murinus	63.21	3.00e-74	269.00
IUUC-Mdo-062454	Monodelphis domestica	63.21	3.00e-74	269.00
IUUC-Mmu-063913	Mus musculus	63.38	9.00e-75	271.00
IUUC-Mpu-066125	Mustela putorius furo	63.21	3.00e-74	269.00
IUUC-Mlu-068007	Myotis lucifugus	63.21	3.00e-74	269.00
IUUC-Nle-069101	Nomascus leucogenys	63.21	3.00e-74	269.00
IUUC-Opr-071075	Ochotona princeps	63.21	3.00e-74	269.00
IUUC-Ont-072253	Oreochromis niloticus	63.55	2.00e-74	270.00
IUUC-Oan-073107	Ornithorhynchus anatinus	45.54	5.00e-46	176.00
IUUC-Ocu-074583	Oryctolagus cuniculus	63.21	3.00e-74	269.00
IUUC-Ola-086586	Oryzias latipes	70.39	2.00e-60	224.00
IUUC-Oga-089047	Otolemur garnettii	63.21	3.00e-74	269.00
IUUC-Oar-089904	Ovis aries	58.96	1.00e-67	248.00
IUUC-Ptr-090678	Pan troglodytes	63.21	3.00e-74	269.00
IUUC-Pan-092090	Papio anubis	63.21	3.00e-74	269.00
IUUC-Psi-093765	Pelodiscus sinensis	63.21	3.00e-74	269.00
IUUC-Pma-094650	Petromyzon marinus	62.21	1.00e-76	277.00
IUUC-Pfo-096131	Poecilia formosa	63.21	9.00e-75	271.00
IUUC-Pab-098709	Pongo abelii	63.21	3.00e-74	269.00
IUUC-Pca-100581	Procavia capensis	61.50	3.00e-62	229.00
IUUC-Pva-103066	Pteropus vampyrus	63.21	3.00e-74	269.00
IUUC-Rno-105224	Rattus norvegicus	63.21	3.00e-74	269.00
IUUC-Sha-107209	Sarcophilus harrisii	53.05	3.00e-58	216.00
IUUC-Sar-113277	Sorex araneus	54.25	8.00e-58	214.00
IUUC-Ssc-115478	Sus scrofa	63.21	3.00e-74	269.00
IUUC-Tgu-117479	Taeniopygia guttata	62.74	6.00e-74	268.00
IUUC-Tru-118451	Takifugu rubripes	60.99	2.00e-69	253.00
IUUC-Tsy-119029	Tarsius syrichta	67.53	2.00e-54	202.00
IUUC-Tni-120563	Tetraodon nigroviridis	46.01	6.00e-50	188.00
IUUC-Tbe-128097	Tupaia belangeri	63.21	7.00e-74	268.00
IUUC-Ttr-128195	Tursiops truncatus	52.29	2.00e-62	230.00
IUUC-Vpa-130754	Vicugna pacos	63.21	3.00e-74	269.00
IUUC-Xtr-132275	Xenopus tropicalis	59.64	8.00e-73	265.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence