iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048847

Ensembl Protein ID

ENSSTOP00000014067.2

UniProt Accession

I3MQ83; I3MQ83_ICTTR

Genbank Protein ID

ENSSTOP00000014067

Protein Name

Coronin

Genbank Nucleotide ID

AGTP01072309

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000015711.2	ENSSTOT00000015714.2	ENSSTOP00000014067.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-16	58.4	80	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt++v ++++   +d  ++sGs D+t++vW 
   Q: 80   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQ 111
           8***********977799*************7 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KNDQCYEDIR VSRVTWDSTF CAVNPKFLAV IVEASGGGAF 60
LVLPLNKTGR IDKAYPTVCG HTGPVLDIDW CPHNDEVIAS GSEDCTVMVW QIPENGLASP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTGCAGA CATGTCCTTT CGCAAAGTGG TTCGGCAGAG CAAATTCCGG CATGTGTTTG 60
GCCAACCGGT CAAGAATGAC CAATGCTACG AGGACATTCG CGTGTCCCGT GTTACCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	94.07	0.00e+00	947.00
IUUC-Aca-005056	Anolis carolinensis	80.82	0.00e+00	817.00
IUUC-Bta-012984	Bos taurus	91.58	0.00e+00	928.00
IUUC-Cja-019498	Callithrix jacchus	93.29	0.00e+00	932.00
IUUC-Cfa-020937	Canis familiaris	95.86	0.00e+00	870.00
IUUC-Cpo-021866	Cavia porcellus	91.15	0.00e+00	907.00
IUUC-Csa-023561	Chlorocebus sabaeus	93.46	0.00e+00	940.00
IUUC-Dno-029770	Dasypus novemcinctus	87.70	0.00e+00	868.00
IUUC-Dor-030989	Dipodomys ordii	94.03	0.00e+00	926.00
IUUC-Eca-033901	Equus caballus	93.66	0.00e+00	920.00
IUUC-Fca-036494	Felis catus	94.27	0.00e+00	904.00
IUUC-Fal-036737	Ficedula albicollis	83.20	0.00e+00	840.00
IUUC-Ggo-045035	Gorilla gorilla	93.87	0.00e+00	938.00
IUUC-Hsa-046154	Homo sapiens	93.66	0.00e+00	936.00
IUUC-Laf-054566	Loxodonta africana	92.40	0.00e+00	900.00
IUUC-Mcc-054879	Macaca mulatta	93.46	0.00e+00	941.00
IUUC-Mmr-060910	Microcebus murinus	93.22	0.00e+00	932.00
IUUC-Mmu-063455	Mus musculus	94.23	0.00e+00	948.00
IUUC-Mpu-066350	Mustela putorius furo	93.46	0.00e+00	927.00
IUUC-Mlu-067353	Myotis lucifugus	94.44	0.00e+00	926.00
IUUC-Nle-069161	Nomascus leucogenys	93.66	0.00e+00	931.00
IUUC-Opr-071106	Ochotona princeps	92.18	0.00e+00	914.00
IUUC-Oga-088805	Otolemur garnettii	91.82	0.00e+00	935.00
IUUC-Ptr-091484	Pan troglodytes	93.66	0.00e+00	936.00
IUUC-Pan-091843	Papio anubis	93.25	0.00e+00	932.00
IUUC-Pab-097835	Pongo abelii	94.07	0.00e+00	939.00
IUUC-Pca-100411	Procavia capensis	81.31	0.00e+00	798.00
IUUC-Pva-102659	Pteropus vampyrus	93.87	0.00e+00	934.00
IUUC-Rno-106070	Rattus norvegicus	93.00	0.00e+00	939.00
IUUC-Sha-106609	Sarcophilus harrisii	94.37	0.00e+00	717.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence