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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063812
UUCD1 version UUC-MuM-00021
Ensembl Protein ID ENSMUSP00000037055.7
UniProt Accession Q5NCC3; TRI41_MOUSE
Genbank Protein ID CAI35108.1; EDL33789.1
Protein Name E3 ubiquitin-protein ligase TRIM41; RING-type E3 ubiquitin transferase TRIM41; Tripartite motif-containing protein 41
Genbank Nucleotide ID AL645849; CH466575
Gene Name Trim41
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000040365.14 ENSMUST00000047145.13 ENSMUSP00000037055.7
ENSMUSG00000040365.14 ENSMUST00000131888.7 ENSMUSP00000119707.1
ENSMUSG00000040365.14 ENSMUST00000138019.1 ENSMUSP00000118789.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IIDHINT
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
mUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 18248090
Classification
Family E-value Score Start End
E3 activity/RING/RING 2.40e-07 32.3 20 48
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw 29
           CaiCl+ f d p++ +CgH f++ C+ q w
   Q: 20   CAICLDYFTD-PVSIGCGHNFCRVCVtQLW 48
           **********.**************98888 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C.
 Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C.
Protein Sequence
(Fasta)
MAAVAMTPNP VQTLQEEAVC AICLDYFTDP VSIGCGHNFC RVCVTQLWGG EDEEDRDELD 60
REEEEEEVGE EEEVEAVGAG GGWDTPMREE DYEGDMEEEA EEEEEVFWSS GIGGSNWDNM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063812|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGTCCCTTC TGCAATCGTC CGTGCCTGGT CGGTAGGATG GCGCTAGGCC GCTGCGGTTG 60
GAGCACGGAG AACAGGGCGC TGCTCAACGT CCTCGCCACC CTCCGCTGTC CGTTCCCGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063812|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PRINTS

PR01407--BUTYPHLNCDUF
SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0042802--F:identical protein binding
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
KEGG mmu:211007
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001322 Ailuropoda melanoleuca 94.95 0.00e+00 757.00
IUUC-Apl-003945 Anas platyrhynchos 48.37 5.00e-117 414.00
IUUC-Aca-005336 Anolis carolinensis 50.98 1.00e-125 443.00
IUUC-Bta-013326 Bos taurus 96.24 0.00e+00 774.00
IUUC-Cja-019205 Callithrix jacchus 84.79 0.00e+00 831.00
IUUC-Cfa-021129 Canis familiaris 96.48 0.00e+00 738.00
IUUC-Cpo-021839 Cavia porcellus 79.52 0.00e+00 869.00
IUUC-Csa-023274 Chlorocebus sabaeus 96.50 4.00e-165 574.00
IUUC-Dno-029811 Dasypus novemcinctus 91.76 0.00e+00 838.00
IUUC-Dor-030241 Dipodomys ordii 89.70 0.00e+00 833.00
IUUC-Ete-032275 Echinops telfairi 94.07 0.00e+00 754.00
IUUC-Eca-033589 Equus caballus 94.69 0.00e+00 728.00
IUUC-Eeu-034925 Erinaceus europaeus 93.59 5.00e-153 533.00
IUUC-Fca-035840 Felis catus 96.70 0.00e+00 739.00
IUUC-Gga-041240 Gallus gallus 53.29 3.00e-132 465.00
IUUC-Ggo-044681 Gorilla gorilla 96.14 9.00e-146 510.00
IUUC-Hsa-046509 Homo sapiens 96.19 0.00e+00 717.00
IUUC-Itr-049027 Ictidomys tridecemlineatus 93.03 0.00e+00 881.00
IUUC-Laf-053825 Loxodonta africana 95.07 0.00e+00 750.00
IUUC-Mcc-055711 Macaca mulatta 94.09 0.00e+00 718.00
IUUC-Meu-056203 Macropus eugenii 81.20 4.00e-90 325.00
IUUC-Mga-059640 Meleagris gallopavo 51.11 9.00e-73 266.00
IUUC-Mmr-060876 Microcebus murinus 96.70 0.00e+00 747.00
IUUC-Mdo-062529 Monodelphis domestica 88.91 0.00e+00 690.00
IUUC-Mpu-066336 Mustela putorius furo 96.70 0.00e+00 738.00
IUUC-Mlu-067141 Myotis lucifugus 87.05 0.00e+00 809.00
IUUC-Nle-069155 Nomascus leucogenys 95.60 1.00e-164 573.00
IUUC-Opr-070782 Ochotona princeps 74.09 2.00e-117 415.00
IUUC-Ocu-073999 Oryctolagus cuniculus 88.49 0.00e+00 857.00
IUUC-Oga-088046 Otolemur garnettii 96.04 0.00e+00 741.00
IUUC-Oar-090410 Ovis aries 92.04 0.00e+00 723.00
IUUC-Pan-092338 Papio anubis 96.50 4.00e-164 571.00
IUUC-Pab-098117 Pongo abelii 96.18 9.00e-165 573.00
IUUC-Pop-099794 Populus trichocarpa 41.86 5.00e-07 47.00
IUUC-Pca-100768 Procavia capensis 96.20 6.00e-85 308.00
IUUC-Pva-102341 Pteropus vampyrus 85.49 0.00e+00 704.00
IUUC-Rno-106006 Rattus norvegicus 96.99 0.00e+00 943.00
IUUC-Sha-106482 Sarcophilus harrisii 87.80 0.00e+00 680.00
IUUC-Sar-113654 Sorex araneus 91.21 0.00e+00 753.00
IUUC-Ssc-115807 Sus scrofa 94.65 3.00e-117 415.00
Created Date 25-Jun-2017

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