iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107546

Ensembl Protein ID

ENSSHAP00000007890.1

UniProt Accession

G3VXI5; G3VXI5_SARHA

Genbank Protein ID

ENSSHAP00000007890

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01174604

Gene Name

WDR27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000006847.1	ENSSHAT00000007953.1	ENSSHAP00000007890.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-23	81.6	549	583
UBD/Beta-Prp	2.60e-43	148.5	505	820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH++ vt++ + +d + lvs+s D t+++W+++t 
   Q: 549  GHNGAVTSVGWsHDrKWLVSASEDRTLRIWSVKTT 583
           8**********99999***************9875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk..g 92
            +++++ i+c+++s d+ +la g +d+ + v++ +   +   ++gh+++vt+v +s+d+k+lv++seDrt+++w+++t + ++ l    
   Q: 505  VASKTTAIYCLQYSGDGLYLACGLADHLLLVFKSSLTRVPTVFQGHNGAVTSVGWSHDRKWLVSASEDRTLRIWSVKTTESTVFLDkdM 593
           5678999*****************************9999999***********************************99999999666 PP
   S: 93   hedsvlslsfspsgdklv..sGshdrtirvwdletgqclee.............tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWd 165
            ++ ++ ++f+  + +++  sGs+   ++ +   ++ +l+                +   ++++  +++++   ++ + + +r + ++d
   Q: 594  LSKPIRVTQFYYMDAFILlsSGSEFHLLKYYIDTQKDELKRykqknkskivktfSMTSAVEITSLSAINDFYsYIVLTTGSNRGLEIFD 682
           7899999999996655554599*******9644444444446666666666654444445567777788888555678899999***** PP
   S: 166  lktgkllrtltgghtdsvyslsfdsng..........kelvsgsldgtvklwdlqtgecvrtlnghtdn..vksvrfspnderlvsgss 242
           l+ ++ +      h +s + +  ++ +          + +++ +    +klwd++t +c r+++gh +   ++ +  sp + ++++gs+
   Q: 683  LNVDSSVAVIPDIHSRSAHQICQNKGSafaaqpfenyNLFLTTAIGDAIKLWDIRTLRCERRFEGHLNRchPCAISISPCGRYIACGSE 771
           **********9999999999996665566666788889****************************976115666667*********** PP
   S: 243  DgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniw 292
           D+  +i+ + s+++ ++l++  ++v  va+ +++++ l++++ d+k++++
   Q: 772  DKHAYIYEMGSSTFSHKLAGYTETVLNVAF-NPSNPQLATATLDGKLQLF 820
           ******************************.**************99876 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MEASENASCN KVSYVVNIVQ ETHLMESEES ASHVQLACSQ HYCAFPLNGN KLCIWNTNSP 60
FNQPLHLEGH HQSITAVTFG NQVNPLFVCS ASCDYVIVWN LLECEERILE GSTPQGTVIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGACACA CACACACACA CAGAGGGAGA CGGGGAGAGG GAGACAGGGG AGAGGCAAAA 60
GAGACTGATG GAGAAAGAGG GGAGGGAGAA AGAGAGGAGA GAGAGAGAGA GAGAGAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002258	Ailuropoda melanoleuca	53.02	0.00e+00	722.00
IUUC-Aca-004807	Anolis carolinensis	61.94	0.00e+00	1030.00
IUUC-Bta-013316	Bos taurus	54.83	0.00e+00	886.00
IUUC-Cja-018825	Callithrix jacchus	55.52	0.00e+00	971.00
IUUC-Cfa-020895	Canis familiaris	56.33	0.00e+00	951.00
IUUC-Cpo-022282	Cavia porcellus	53.21	0.00e+00	888.00
IUUC-Csa-023439	Chlorocebus sabaeus	55.97	0.00e+00	902.00
IUUC-Cho-025046	Choloepus hoffmanni	54.44	3.00e-180	625.00
IUUC-Dre-028376	Danio rerio	43.86	0.00e+00	631.00
IUUC-Dno-029649	Dasypus novemcinctus	64.06	0.00e+00	873.00
IUUC-Dor-030824	Dipodomys ordii	48.28	0.00e+00	634.00
IUUC-Eca-033270	Equus caballus	58.79	0.00e+00	993.00
IUUC-Fca-036149	Felis catus	53.60	0.00e+00	909.00
IUUC-Fal-037410	Ficedula albicollis	56.23	0.00e+00	763.00
IUUC-Gmo-038923	Gadus morhua	40.83	1.00e-138	486.00
IUUC-Gga-040974	Gallus gallus	55.40	0.00e+00	880.00
IUUC-Gac-042310	Gasterosteus aculeatus	38.54	1.00e-115	410.00
IUUC-Ggo-044557	Gorilla gorilla	56.40	0.00e+00	984.00
IUUC-Hsa-046312	Homo sapiens	55.45	0.00e+00	963.00
IUUC-Itr-049033	Ictidomys tridecemlineatus	53.55	0.00e+00	888.00
IUUC-Laf-054450	Loxodonta africana	59.95	0.00e+00	960.00
IUUC-Mcc-055807	Macaca mulatta	52.30	0.00e+00	749.00
IUUC-Meu-056116	Macropus eugenii	55.41	1.00e-111	397.00
IUUC-Mga-060088	Meleagris gallopavo	54.42	0.00e+00	758.00
IUUC-Mdo-062857	Monodelphis domestica	79.54	0.00e+00	1354.00
IUUC-Mmu-063220	Mus musculus	54.82	0.00e+00	775.00
IUUC-Mpu-066921	Mustela putorius furo	51.40	0.00e+00	832.00
IUUC-Mlu-067717	Myotis lucifugus	49.84	0.00e+00	669.00
IUUC-Nle-069061	Nomascus leucogenys	46.91	0.00e+00	743.00
IUUC-Opr-070612	Ochotona princeps	48.84	4.00e-69	256.00
IUUC-Ont-072187	Oreochromis niloticus	42.43	8.00e-179	620.00
IUUC-Oan-072701	Ornithorhynchus anatinus	58.22	2.00e-151	529.00
IUUC-Ocu-074602	Oryctolagus cuniculus	54.35	0.00e+00	919.00
IUUC-Ola-086633	Oryzias latipes	37.52	2.00e-130	459.00
IUUC-Oga-088499	Otolemur garnettii	57.11	0.00e+00	967.00
IUUC-Oar-089256	Ovis aries	52.58	0.00e+00	840.00
IUUC-Ptr-091545	Pan troglodytes	51.21	2.00e-168	585.00
IUUC-Pan-092299	Papio anubis	56.00	0.00e+00	978.00
IUUC-Psi-093010	Pelodiscus sinensis	63.80	0.00e+00	1056.00
IUUC-Pab-097646	Pongo abelii	49.31	2.00e-161	562.00
IUUC-Pca-100720	Procavia capensis	47.84	4.00e-126	445.00
IUUC-Pva-102808	Pteropus vampyrus	48.74	0.00e+00	749.00
IUUC-Rno-105715	Rattus norvegicus	54.93	0.00e+00	896.00
IUUC-Sar-113543	Sorex araneus	44.12	0.00e+00	679.00
IUUC-Ssc-116335	Sus scrofa	60.50	1.00e-40	159.00
IUUC-Tgu-117249	Taeniopygia guttata	55.83	0.00e+00	790.00
IUUC-Tsy-119238	Tarsius syrichta	53.64	0.00e+00	730.00
IUUC-Tni-120639	Tetraodon nigroviridis	35.20	2.00e-56	212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence