iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098251

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01052593

Gene Name

TRIM8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000002607.2	ENSPPYT00000003136.2	ENSPPYP00000003032.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	32.3	15	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl  f + p+ lpC+H f++ C+ ++w     + s+  rCP C+
   Q: 15   CPICLHVFVE-PVQLPCKHNFCRGCIgEAW----AKDSGLVRCPECN 56
           ********99.999****************....889*********7 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAENWKNCFE EELICPICLH VFVEPVQLPC KHNFCRGCIG EAWAKDSGLV RCPECNQAYN 60
QKPGLEKNLK LTNIVEKFNA LHVEKPPAAL HCVFCRRGPP LPAQKVCLRC EAPCCQSHVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGA ATTGGAAGAA CTGCTTCGAG GAGGAGCTCA TCTGCCCCAT CTGCCTGCAC 60
GTTTTCGTGG AGCCAGTGCA GCTGCCGTGC AAACACAACT TCTGCCGGGG CTGCATCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1900182--P:positive regulation of protein localization to nucleus
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001258	Ailuropoda melanoleuca	95.11	0.00e+00	1072.00
IUUC-Apl-004223	Anas platyrhynchos	82.43	0.00e+00	938.00
IUUC-Aca-005106	Anolis carolinensis	82.58	0.00e+00	966.00
IUUC-Ame-011348	Astyanax mexicanus	64.67	0.00e+00	718.00
IUUC-Bta-012787	Bos taurus	95.83	0.00e+00	1081.00
IUUC-Cja-019471	Callithrix jacchus	96.01	0.00e+00	1082.00
IUUC-Cfa-020052	Canis familiaris	95.28	0.00e+00	1075.00
IUUC-Cpo-022491	Cavia porcellus	94.60	0.00e+00	679.00
IUUC-Csa-023544	Chlorocebus sabaeus	96.01	0.00e+00	1083.00
IUUC-Dre-028013	Danio rerio	64.12	0.00e+00	720.00
IUUC-Dno-029676	Dasypus novemcinctus	95.10	0.00e+00	1077.00
IUUC-Dor-030402	Dipodomys ordii	94.37	0.00e+00	1068.00
IUUC-Ete-033188	Echinops telfairi	90.05	0.00e+00	1013.00
IUUC-Eca-033524	Equus caballus	94.75	0.00e+00	1068.00
IUUC-Eeu-034979	Erinaceus europaeus	97.61	9.00e-143	500.00
IUUC-Fca-036362	Felis catus	95.28	0.00e+00	1074.00
IUUC-Fal-036652	Ficedula albicollis	81.04	0.00e+00	918.00
IUUC-Gmo-039405	Gadus morhua	58.44	5.00e-176	610.00
IUUC-Gga-040813	Gallus gallus	82.21	0.00e+00	940.00
IUUC-Gac-041792	Gasterosteus aculeatus	61.99	0.00e+00	650.00
IUUC-Ggo-044962	Gorilla gorilla	96.37	0.00e+00	1086.00
IUUC-Hsa-046158	Homo sapiens	96.19	0.00e+00	1085.00
IUUC-Itr-048118	Ictidomys tridecemlineatus	95.46	0.00e+00	1076.00
IUUC-Lch-049433	Latimeria chalumnae	76.96	0.00e+00	829.00
IUUC-Loc-052026	Lepisosteus oculatus	73.61	0.00e+00	833.00
IUUC-Laf-054159	Loxodonta africana	92.22	0.00e+00	855.00
IUUC-Mcc-055490	Macaca mulatta	96.01	0.00e+00	1083.00
IUUC-Meu-056549	Macropus eugenii	84.35	0.00e+00	690.00
IUUC-Mga-059334	Meleagris gallopavo	82.40	0.00e+00	936.00
IUUC-Mmr-061672	Microcebus murinus	95.64	0.00e+00	1080.00
IUUC-Mdo-061849	Monodelphis domestica	85.51	0.00e+00	881.00
IUUC-Mmu-063537	Mus musculus	94.37	0.00e+00	1068.00
IUUC-Mpu-065762	Mustela putorius furo	95.46	0.00e+00	1077.00
IUUC-Mlu-066979	Myotis lucifugus	90.21	0.00e+00	700.00
IUUC-Nle-069419	Nomascus leucogenys	96.37	0.00e+00	1086.00
IUUC-Opr-070981	Ochotona princeps	94.74	0.00e+00	1072.00
IUUC-Ont-072053	Oreochromis niloticus	56.83	2.00e-173	602.00
IUUC-Oan-073608	Ornithorhynchus anatinus	82.56	0.00e+00	780.00
IUUC-Ocu-074694	Oryctolagus cuniculus	94.74	0.00e+00	1031.00
IUUC-Ola-086949	Oryzias latipes	58.22	9.00e-174	603.00
IUUC-Oga-089175	Otolemur garnettii	95.83	0.00e+00	1082.00
IUUC-Oar-089591	Ovis aries	85.19	0.00e+00	837.00
IUUC-Ptr-091309	Pan troglodytes	96.70	0.00e+00	1077.00
IUUC-Pan-091903	Papio anubis	96.01	0.00e+00	1083.00
IUUC-Psi-093293	Pelodiscus sinensis	80.54	0.00e+00	921.00
IUUC-Pfo-097191	Poecilia formosa	58.04	1.00e-170	593.00
IUUC-Pca-100504	Procavia capensis	95.28	0.00e+00	1077.00
IUUC-Pva-102320	Pteropus vampyrus	94.37	0.00e+00	1025.00
IUUC-Rno-105545	Rattus norvegicus	94.56	0.00e+00	1067.00
IUUC-Ssc-116121	Sus scrofa	95.83	0.00e+00	1081.00
IUUC-Tgu-116724	Taeniopygia guttata	82.21	0.00e+00	934.00
IUUC-Tru-118048	Takifugu rubripes	57.31	3.00e-177	614.00
IUUC-Tni-120856	Tetraodon nigroviridis	58.36	1.00e-168	585.00
IUUC-Tbe-127400	Tupaia belangeri	83.24	2.00e-154	538.00
IUUC-Ttr-128233	Tursiops truncatus	94.92	0.00e+00	1058.00
IUUC-Xtr-132578	Xenopus tropicalis	80.76	0.00e+00	919.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence