iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-123647

Ensembl Protein ID

TRIAE_CS42_U_TGACv1_644235_AA2138190.1

UniProt Accession

W5GSC0; W5GSC0_WHEAT

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_U_TGACv1_644235_AA2138190	TRIAE_CS42_U_TGACv1_644235_AA2138190.1	TRIAE_CS42_U_TGACv1_644235_AA2138190.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.15	2.00e-40	163.00	IUUC-Dme-031700
E3 activity/RING/RING	37.09	4.00e-43	172.00	IUUC-Hsa-046357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Triticum aestivum

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPGSSIVSV TEVPESDCGD RGLSEALSSI RLDGDSTSKP SWAASLVNVG LSSLTGLNDL 60
LECPVCTNSM RPPILQCPNG HTICSSCKHR VDNHCPTCRQ ELGNIRCLAL EKVAESIQLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCCACGAGA TACGATTGAT TTCTTGTTTC ACAAAAAAGA GAAAGCAAAA CCGAAATATC 60
CCCCCGCCTC CACCACTGTT CGTCTTCCCC TCCCCTCCTC CTACACCTTC CCCCGTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	100.00	0.00e+00	649.00
IUUC-Aml-001186	Ailuropoda melanoleuca	37.02	1.00e-44	173.00
IUUC-Atr-003118	Amborella trichopoda	72.80	2.00e-119	422.00
IUUC-Apl-003813	Anas platyrhynchos	37.36	3.00e-44	172.00
IUUC-Aca-005014	Anolis carolinensis	37.36	3.00e-44	172.00
IUUC-Aly-006207	Arabidopsis lyrata	68.05	4.00e-128	451.00
IUUC-Ath-007049	Arabidopsis thaliana	68.17	5.00e-128	450.00
IUUC-Acl-008349	Aspergillus clavatus	29.41	2.00e-05	44.70
IUUC-Ame-011196	Astyanax mexicanus	37.32	1.00e-45	177.00
IUUC-Bta-012887	Bos taurus	37.02	2.00e-44	173.00
IUUC-Bdi-014200	Brachypodium distachyon	97.75	0.00e+00	627.00
IUUC-Bol-015523	Brassica oleracea	76.34	3.00e-123	435.00
IUUC-Bra-017336	Brassica rapa	77.39	4.00e-124	437.00
IUUC-Cel-018320	Caenorhabditis elegans	33.89	1.00e-34	141.00
IUUC-Cja-019796	Callithrix jacchus	37.09	3.00e-44	172.00
IUUC-Cfa-020642	Canis familiaris	37.09	1.00e-44	173.00
IUUC-Cpo-022348	Cavia porcellus	37.36	3.00e-44	172.00
IUUC-Csa-023974	Chlorocebus sabaeus	37.09	3.00e-44	172.00
IUUC-Cho-024933	Choloepus hoffmanni	35.06	2.00e-39	156.00
IUUC-Cin-025674	Ciona intestinalis	35.98	2.00e-41	163.00
IUUC-Csv-026233	Ciona savignyi	36.40	1.00e-41	163.00
IUUC-Dre-028041	Danio rerio	37.32	2.00e-45	176.00
IUUC-Dno-029764	Dasypus novemcinctus	37.36	3.00e-44	172.00
IUUC-Dor-030489	Dipodomys ordii	30.81	1.00e-19	89.70
IUUC-Dme-031700	Drosophila melanogaster	35.60	6.00e-37	148.00
IUUC-Ete-032423	Echinops telfairi	37.64	8.00e-44	171.00
IUUC-Eca-033536	Equus caballus	37.36	3.00e-44	172.00
IUUC-Eeu-035314	Erinaceus europaeus	36.52	3.00e-44	172.00
IUUC-Fca-035362	Felis catus	37.09	3.00e-44	172.00
IUUC-Fal-037487	Ficedula albicollis	37.05	6.00e-45	174.00
IUUC-Gmo-039091	Gadus morhua	35.06	7.00e-38	151.00
IUUC-Gga-040269	Gallus gallus	37.36	3.00e-44	172.00
IUUC-Gac-042282	Gasterosteus aculeatus	37.36	6.00e-45	174.00
IUUC-Gma-042926	Glycine max	72.30	1.00e-121	429.00
IUUC-Ggo-045444	Gorilla gorilla	37.09	3.00e-44	172.00
IUUC-Hsa-046357	Homo sapiens	37.09	3.00e-44	172.00
IUUC-Hvu-047574	Hordeum vulgare	99.04	0.00e+00	645.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	37.36	3.00e-44	172.00
IUUC-Lch-049504	Latimeria chalumnae	37.36	2.00e-44	172.00
IUUC-Lpe-050879	Leersia perrieri	93.25	1.00e-165	575.00
IUUC-Loc-052191	Lepisosteus oculatus	37.32	8.00e-45	174.00
IUUC-Laf-053668	Loxodonta africana	37.36	3.00e-44	172.00
IUUC-Mcc-054640	Macaca mulatta	37.09	3.00e-44	172.00
IUUC-Meu-055922	Macropus eugenii	34.66	2.00e-38	152.00
IUUC-Mtr-058699	Medicago truncatula	76.43	1.00e-123	436.00
IUUC-Mga-059503	Meleagris gallopavo	38.55	4.00e-44	172.00
IUUC-Mmr-060794	Microcebus murinus	37.36	3.00e-44	172.00
IUUC-Mdo-061971	Monodelphis domestica	35.46	9.00e-40	157.00
IUUC-Mmu-063876	Mus musculus	37.82	2.00e-44	172.00
IUUC-Mac-065014	Musa acuminata	75.46	3.00e-126	444.00
IUUC-Mpu-066488	Mustela putorius furo	37.09	3.00e-44	172.00
IUUC-Mlu-067207	Myotis lucifugus	37.85	1.00e-44	174.00
IUUC-Nle-069706	Nomascus leucogenys	37.09	3.00e-44	172.00
IUUC-Opr-070341	Ochotona princeps	26.58	7.00e-11	61.60
IUUC-Ont-071849	Oreochromis niloticus	37.36	7.00e-45	174.00
IUUC-Oan-073701	Ornithorhynchus anatinus	24.83	1.00e-10	60.80
IUUC-Ocu-074876	Oryctolagus cuniculus	37.09	4.00e-44	172.00
IUUC-Oba-075454	Oryza barthii	91.64	1.00e-163	569.00
IUUC-Obr-076037	Oryza brachyantha	70.00	1.00e-120	426.00
IUUC-Ogl-077712	Oryza glaberrima	91.64	1.00e-163	569.00
IUUC-Ogu-078910	Oryza glumaepatula	91.64	6.00e-164	570.00
IUUC-Oin-079749	Oryza indica	91.64	1.00e-163	569.00
IUUC-Olo-080244	Oryza longistaminata	75.29	9.00e-121	427.00
IUUC-Ome-081318	Oryza meridionalis	92.28	3.00e-164	571.00
IUUC-Oni-083109	Oryza nivara	91.64	1.00e-163	569.00
IUUC-Opu-084065	Oryza punctata	91.96	7.00e-164	570.00
IUUC-Oru-084785	Oryza rufipogon	91.64	1.00e-163	569.00
IUUC-Osa-085610	Oryza sativa	91.64	1.00e-163	569.00
IUUC-Ola-086814	Oryzias latipes	37.36	6.00e-45	174.00
IUUC-Oga-088399	Otolemur garnettii	37.36	3.00e-44	172.00
IUUC-Oar-089323	Ovis aries	36.68	3.00e-44	172.00
IUUC-Ptr-090692	Pan troglodytes	35.79	4.00e-44	172.00
IUUC-Pan-092012	Papio anubis	37.09	3.00e-44	172.00
IUUC-Psi-093687	Pelodiscus sinensis	37.09	3.00e-44	172.00
IUUC-Pma-094387	Petromyzon marinus	38.64	1.00e-45	177.00
IUUC-Ppa-095212	Physcomitrella patens	77.04	1.00e-122	432.00
IUUC-Pfo-097134	Poecilia formosa	37.36	6.00e-45	174.00
IUUC-Pab-097555	Pongo abelii	37.09	3.00e-44	172.00
IUUC-Pop-100033	Populus trichocarpa	77.39	6.00e-125	441.00
IUUC-Pca-100328	Procavia capensis	34.92	2.00e-36	147.00
IUUC-Ppe-101960	Prunus persica	77.57	1.00e-125	443.00
IUUC-Pva-102368	Pteropus vampyrus	30.77	1.00e-09	57.80
IUUC-Rno-104866	Rattus norvegicus	37.36	2.00e-44	172.00
IUUC-Sha-106547	Sarcophilus harrisii	37.02	2.00e-44	173.00
IUUC-Smo-109412	Selaginella moellendorffii	69.23	5.00e-126	444.00
IUUC-Sit-110595	Setaria italica	90.35	1.00e-169	589.00
IUUC-Sly-111259	Solanum lycopersicum	77.57	1.00e-124	439.00
IUUC-Stu-112571	Solanum tuberosum	77.95	6.00e-125	441.00
IUUC-Sbi-114090	Sorghum bicolor	89.74	6.00e-167	580.00
IUUC-Ssc-116441	Sus scrofa	36.11	2.00e-39	157.00
IUUC-Tgu-116579	Taeniopygia guttata	37.36	3.00e-44	172.00
IUUC-Tru-118250	Takifugu rubripes	37.64	8.00e-44	171.00
IUUC-Tsy-119548	Tarsius syrichta	30.21	1.00e-06	47.00
IUUC-Tni-120488	Tetraodon nigroviridis	37.45	3.00e-42	166.00
IUUC-Tca-121228	Theobroma cacao	73.21	5.00e-126	444.00
IUUC-Tur-126259	Triticum urartu	66.12	4.00e-120	424.00
IUUC-Ttr-129166	Tursiops truncatus	39.00	1.00e-40	160.00
IUUC-Vpa-130799	Vicugna pacos	31.58	1.00e-18	86.70
IUUC-Vvi-131233	Vitis vinifera	67.42	8.00e-123	433.00
IUUC-Xtr-132553	Xenopus tropicalis	38.55	3.00e-44	172.00
IUUC-Xma-133670	Xiphophorus maculatus	37.36	6.00e-45	174.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence