iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090676

Ensembl Protein ID

ENSPTRP00000052062.2

UniProt Accession

H2R8V8; H2R8V8_PANTR

Genbank Protein ID

JAA09813.1; JAA19649.1; JAA32069.1; JAA38620.1

Protein Name

Metal response element binding transcription factor 2

Genbank Nucleotide ID

AACZ03002971; GABF01002496; GABD01001031; GABE01006119

Gene Name

MTF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000000965.6	ENSPTRT00000058993.2	ENSPTRP00000052062.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.10e-11	42.9	103	155

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsek.wiCpkCr 52
           +vC +C+e++++   ++v C+kC + +H+ C+ + +++++ +s++ w C++C 
   Q: 103  MVCTICQEEYSEAPnEMVICDKCGQGYHQLCHTPHIDSSVIDSDEkWLCRQCV 155
           79********987569********************9999888777******7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL 60
FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGCCATTC GGCACCGGAG TCGCTCCGCG CTCCCAGAAT GCACCGGCAG TCCGCGGGAA 60
ACCAAAATGG CGAGGGGCTG TATTGAAGTG GGCTGTGTTT GAGGCCGGTG TAAGAACGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025894--Mtf2_C_dom
IPR002999--Tudor
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF14061--Mtf2_C
PF00628--PHD

SMART

SM00249--PHD
SM00333--TUDOR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0035098--C:ESC/E(Z) complex
GO:0008270--F:zinc ion binding
GO:0061086--P:negative regulation of histone H3-K27 methylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0061087--P:positive regulation of histone H3-K27 methylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0007379--P:segment specification
GO:0048863--P:stem cell differentiation
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001293	Ailuropoda melanoleuca	99.66	0.00e+00	1175.00
IUUC-Apl-004128	Anas platyrhynchos	90.27	0.00e+00	1101.00
IUUC-Aca-004646	Anolis carolinensis	88.99	0.00e+00	985.00
IUUC-Bta-012598	Bos taurus	99.39	0.00e+00	967.00
IUUC-Cja-019930	Callithrix jacchus	99.66	0.00e+00	1206.00
IUUC-Cfa-020413	Canis familiaris	99.49	0.00e+00	1172.00
IUUC-Csa-023605	Chlorocebus sabaeus	99.66	0.00e+00	1181.00
IUUC-Csv-026067	Ciona savignyi	52.30	1.00e-98	352.00
IUUC-Dre-028327	Danio rerio	63.83	0.00e+00	704.00
IUUC-Dno-029487	Dasypus novemcinctus	96.11	0.00e+00	1130.00
IUUC-Dme-031808	Drosophila melanogaster	32.74	4.00e-47	183.00
IUUC-Eca-034332	Equus caballus	98.99	0.00e+00	1195.00
IUUC-Fca-036088	Felis catus	99.49	0.00e+00	1173.00
IUUC-Fal-036851	Ficedula albicollis	90.69	0.00e+00	920.00
IUUC-Gmo-038940	Gadus morhua	64.80	8.00e-144	503.00
IUUC-Gga-041162	Gallus gallus	90.08	0.00e+00	1096.00
IUUC-Gac-041758	Gasterosteus aculeatus	57.69	6.00e-141	494.00
IUUC-Ggo-044658	Gorilla gorilla	100.00	0.00e+00	1182.00
IUUC-Hsa-045895	Homo sapiens	100.00	0.00e+00	1182.00
IUUC-Itr-047940	Ictidomys tridecemlineatus	98.82	0.00e+00	1196.00
IUUC-Lch-050577	Latimeria chalumnae	79.97	0.00e+00	895.00
IUUC-Loc-051747	Lepisosteus oculatus	68.78	0.00e+00	796.00
IUUC-Laf-054500	Loxodonta africana	99.16	0.00e+00	1198.00
IUUC-Mcc-055738	Macaca mulatta	99.66	0.00e+00	1180.00
IUUC-Mga-059203	Meleagris gallopavo	89.93	0.00e+00	1095.00
IUUC-Mmr-061070	Microcebus murinus	98.65	0.00e+00	1165.00
IUUC-Mdo-061878	Monodelphis domestica	95.33	0.00e+00	960.00
IUUC-Mmu-063700	Mus musculus	97.64	0.00e+00	1181.00
IUUC-Mpu-066250	Mustela putorius furo	99.33	0.00e+00	1174.00
IUUC-Mlu-067694	Myotis lucifugus	98.65	0.00e+00	1194.00
IUUC-Nle-069777	Nomascus leucogenys	99.66	0.00e+00	1206.00
IUUC-Ont-072183	Oreochromis niloticus	53.62	7.00e-168	583.00
IUUC-Oan-073204	Ornithorhynchus anatinus	97.52	1.00e-144	504.00
IUUC-Ocu-074279	Oryctolagus cuniculus	98.99	0.00e+00	1197.00
IUUC-Ola-087332	Oryzias latipes	56.00	5.00e-137	481.00
IUUC-Oga-089023	Otolemur garnettii	51.31	3.00e-115	408.00
IUUC-Oar-089543	Ovis aries	99.33	0.00e+00	1174.00
IUUC-Pan-092568	Papio anubis	99.83	0.00e+00	1182.00
IUUC-Psi-092976	Pelodiscus sinensis	90.92	0.00e+00	1115.00
IUUC-Pma-094138	Petromyzon marinus	64.16	1.00e-134	472.00
IUUC-Pfo-097187	Poecilia formosa	50.89	4.00e-158	551.00
IUUC-Pab-097543	Pongo abelii	100.00	0.00e+00	1182.00
IUUC-Pca-100289	Procavia capensis	87.76	0.00e+00	854.00
IUUC-Pva-103007	Pteropus vampyrus	54.95	3.00e-103	369.00
IUUC-Rno-105075	Rattus norvegicus	96.96	0.00e+00	1175.00
IUUC-Sha-106522	Sarcophilus harrisii	97.14	2.00e-122	430.00
IUUC-Ssc-116220	Sus scrofa	99.16	0.00e+00	1172.00
IUUC-Tgu-117230	Taeniopygia guttata	88.61	0.00e+00	1060.00
IUUC-Tru-118228	Takifugu rubripes	53.70	7.00e-159	553.00
IUUC-Tsy-119045	Tarsius syrichta	98.65	0.00e+00	1154.00
IUUC-Tni-120342	Tetraodon nigroviridis	56.47	3.00e-176	611.00
IUUC-Ttr-128691	Tursiops truncatus	99.16	0.00e+00	1170.00
IUUC-Vpa-130085	Vicugna pacos	57.04	1.00e-48	186.00
IUUC-Xtr-132767	Xenopus tropicalis	74.58	0.00e+00	884.00
IUUC-Xma-133635	Xiphophorus maculatus	50.57	1.00e-158	552.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence