iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054488

UUCD1 version

UUC-LoA-00431

Ensembl Protein ID

ENSLAFP00000010474.2

UniProt Accession

G3T9K8; G3T9K8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000012533.2	ENSLAFT00000012530.2	ENSLAFP00000010474.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.61	0.00e+00	980.00	IUUC-Hsa-046029
E3 activity/RING/RING	99.22	0.00e+00	978.00	IUUC-Mmu-064242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

AWPRESGRLR PLPGPLASVR VSVGPECPGA HATGRREGPR HFESPARGRD RDLRPGSGPG 60
RRRPAHLPAR PEVETRRERS RVGLRAELSE GAHARAPPRA SAMASGSVAE CLQQETTCPV 120

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Nucleotide Sequence
(Fasta)

GCCTGGCCCC GCGAGTCCGG TCGGCTGCGC CCACTTCCTG GACCACTTGC CTCGGTACGG 60
GTCTCCGTGG GACCGGAGTG TCCCGGCGCC CACGCAACGG GGCGCCGAGA GGGGCCCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR020457--Znf_B-box_chordata
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01406--BBOXZNFINGER
PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0030904--C:retromer complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0045087--P:innate immune response
GO:0072643--P:interferon-gamma secretion
GO:0002820--P:negative regulation of adaptive immune response
GO:0090281--P:negative regulation of calcium ion import
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:1900041--P:negative regulation of interleukin-2 secretion
GO:0006469--P:negative regulation of protein kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051127--P:positive regulation of actin nucleation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0070206--P:protein trimerization
GO:0042147--P:retrograde transport, endosome to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001890	Ailuropoda melanoleuca	99.01	0.00e+00	975.00
IUUC-Apl-003609	Anas platyrhynchos	40.21	3.00e-96	345.00
IUUC-Aca-004600	Anolis carolinensis	41.22	2.00e-95	343.00
IUUC-Ame-011639	Astyanax mexicanus	34.42	3.00e-69	256.00
IUUC-Bta-013520	Bos taurus	99.61	0.00e+00	986.00
IUUC-Cja-019557	Callithrix jacchus	97.86	0.00e+00	970.00
IUUC-Cfa-020583	Canis familiaris	98.57	0.00e+00	924.00
IUUC-Cpo-021738	Cavia porcellus	90.64	0.00e+00	881.00
IUUC-Csa-023502	Chlorocebus sabaeus	99.61	0.00e+00	986.00
IUUC-Cho-024563	Choloepus hoffmanni	96.40	0.00e+00	626.00
IUUC-Dno-029747	Dasypus novemcinctus	96.79	0.00e+00	912.00
IUUC-Dor-030243	Dipodomys ordii	96.88	0.00e+00	936.00
IUUC-Ete-032749	Echinops telfairi	84.55	0.00e+00	796.00
IUUC-Eca-034246	Equus caballus	99.20	0.00e+00	692.00
IUUC-Eeu-034481	Erinaceus europaeus	88.50	0.00e+00	867.00
IUUC-Fca-036152	Felis catus	98.93	0.00e+00	691.00
IUUC-Fal-037164	Ficedula albicollis	41.05	3.00e-101	361.00
IUUC-Gac-042288	Gasterosteus aculeatus	36.07	2.00e-75	276.00
IUUC-Ggo-044987	Gorilla gorilla	89.68	0.00e+00	887.00
IUUC-Hsa-046029	Homo sapiens	99.61	0.00e+00	986.00
IUUC-Itr-048438	Ictidomys tridecemlineatus	99.42	0.00e+00	961.00
IUUC-Mcc-055352	Macaca mulatta	99.61	0.00e+00	986.00
IUUC-Mmr-060883	Microcebus murinus	99.61	0.00e+00	984.00
IUUC-Mmu-064242	Mus musculus	99.22	0.00e+00	984.00
IUUC-Mpu-065958	Mustela putorius furo	99.22	0.00e+00	989.00
IUUC-Mlu-068005	Myotis lucifugus	85.29	0.00e+00	652.00
IUUC-Nle-069710	Nomascus leucogenys	99.15	0.00e+00	642.00
IUUC-Opr-071200	Ochotona princeps	98.64	0.00e+00	971.00
IUUC-Ocu-074081	Oryctolagus cuniculus	97.80	0.00e+00	845.00
IUUC-Ola-087166	Oryzias latipes	33.76	3.00e-70	259.00
IUUC-Oga-088784	Otolemur garnettii	99.61	0.00e+00	987.00
IUUC-Oar-089433	Ovis aries	99.61	0.00e+00	986.00
IUUC-Ptr-090595	Pan troglodytes	99.61	0.00e+00	986.00
IUUC-Pan-092027	Papio anubis	99.61	0.00e+00	986.00
IUUC-Psi-093179	Pelodiscus sinensis	47.07	2.00e-115	409.00
IUUC-Pfo-096858	Poecilia formosa	33.96	1.00e-68	253.00
IUUC-Pab-098331	Pongo abelii	99.61	0.00e+00	986.00
IUUC-Pca-101091	Procavia capensis	100.00	0.00e+00	989.00
IUUC-Pva-103141	Pteropus vampyrus	99.22	0.00e+00	714.00
IUUC-Rno-105507	Rattus norvegicus	98.83	0.00e+00	979.00
IUUC-Sar-113713	Sorex araneus	90.62	0.00e+00	901.00
IUUC-Ssc-115594	Sus scrofa	95.21	0.00e+00	994.00
IUUC-Tru-118630	Takifugu rubripes	34.46	5.00e-72	265.00
IUUC-Tsy-119235	Tarsius syrichta	98.96	0.00e+00	702.00
IUUC-Tni-120295	Tetraodon nigroviridis	37.58	5.00e-75	275.00
IUUC-Tbe-127796	Tupaia belangeri	88.64	3.00e-139	488.00
IUUC-Ttr-128738	Tursiops truncatus	99.46	0.00e+00	692.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence