iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033521

UUCD1 version

UUC-EqC-00903

Ensembl Protein ID

ENSECAP00000012254.1

UniProt Accession

F7DP19; F7DP19_HORSE

Protein Name

Uncharacterized protein

Gene Name

PLRG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014258.1	ENSECAT00000015264.1	ENSECAP00000012254.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-43	144.0	203	239
UBD/Beta-Prp	1.90e-64	217.9	287	495

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 203  GHLGWVRCIAVePGnQWFVTGSADRTIKIWDLASGKL 239
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdg 138
           gh ++v+ ++++p+ ++lvt+s+D t+++wd++t   vhtl+gh++ v +++ ++    +++G+hd tir+wdl  g+    tl++h++
   Q: 287  GHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGTHDTTIRLWDLVAGKTRV-TLTNHKK 374
           688899999999999999999999999999999999999999999999999999999999999999999999999999999.9999999 PP
   S: 139  vvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght..... 222
           +v+ vv+hp    ++sGs D+ ++ W+ + g+ ++ l+g h+  ++ l+++s+g  lvsg+++gt  lwd +tg   +++++       
   Q: 375  SVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSG-HNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVqpgsl 460
           999999999999999999997.67799999999999998.99999999999998.8999999999999999999887777777778888 PP
   S: 223  ...dnvksvrfspnderlvsgssDgsiriW...dl 251
              + +   +f++ + rl+++ +D++i+++   d+
   Q: 461  dseSGIFACAFDQSESRLLTAEADKTIKVYredDT 495
           88888999999999999999999999999955444 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MVEEVQKHSV HTLVFRSLKR THDMFVADNG KPVPLDEESH KRKMAIKLRN EYGPVLHMPS 60
SKENFKEKGP QNASDSYGHK QYPANQGQEV EYLVTGTHPY PPGPGVALTA DTKIQRMPSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCGAGG TAGAGTGACG CTTGGGTGCT CAGGAGTCGT TTGCTTCCCG ACTGGTTTAC 60
TTTGGCGGCG GGCTTGGTGG GTCGAGGGTG TCGGGAGTCT GGGGAGAGTG GAGGCTGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005662--C:DNA replication factor A complex
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0016607--C:nuclear speck
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0034504--P:protein localization to nucleus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	53.86	1.00e-127	450.00
IUUC-Aml-001605	Ailuropoda melanoleuca	97.66	0.00e+00	1049.00
IUUC-Atr-002757	Amborella trichopoda	48.37	2.00e-128	452.00
IUUC-Apl-003198	Anas platyrhynchos	89.73	0.00e+00	976.00
IUUC-Aca-004683	Anolis carolinensis	89.34	0.00e+00	963.00
IUUC-Aly-005775	Arabidopsis lyrata	53.68	9.00e-126	443.00
IUUC-Ath-007460	Arabidopsis thaliana	52.83	6.00e-126	444.00
IUUC-Ago-007884	Ashbya gossypii	49.14	2.00e-106	379.00
IUUC-Acl-008153	Aspergillus clavatus	63.72	8.00e-128	450.00
IUUC-Afl-008384	Aspergillus flavus	56.03	2.00e-129	455.00
IUUC-Afu-009045	Aspergillus fumigatus	64.33	8.00e-129	453.00
IUUC-Ani-009229	Aspergillus nidulans	62.39	8.00e-129	453.00
IUUC-Ang-009812	Aspergillus niger	64.98	3.00e-123	434.00
IUUC-Aor-010059	Aspergillus oryzae	56.03	2.00e-129	455.00
IUUC-Ate-010351	Aspergillus terreus	62.50	5.00e-135	474.00
IUUC-Ame-011613	Astyanax mexicanus	59.59	3.00e-158	551.00
IUUC-Bgr-012042	Blumeria graminis	63.11	2.00e-134	471.00
IUUC-Bta-012406	Bos taurus	96.50	0.00e+00	1036.00
IUUC-Bci-013760	Botrytis cinerea	62.18	3.00e-133	468.00
IUUC-Bdi-014776	Brachypodium distachyon	56.96	1.00e-130	459.00
IUUC-Bol-016189	Brassica oleracea	52.80	1.00e-126	446.00
IUUC-Bra-018044	Brassica rapa	52.80	2.00e-126	446.00
IUUC-Cel-018651	Caenorhabditis elegans	53.52	6.00e-156	543.00
IUUC-Cja-019974	Callithrix jacchus	95.34	0.00e+00	1030.00
IUUC-Cfa-021085	Canis familiaris	97.67	0.00e+00	1053.00
IUUC-Cpo-021458	Cavia porcellus	95.15	0.00e+00	1031.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	59.27	3.00e-123	434.00
IUUC-Csa-023883	Chlorocebus sabaeus	95.15	0.00e+00	1028.00
IUUC-Cho-024623	Choloepus hoffmanni	94.90	0.00e+00	1004.00
IUUC-Cin-025190	Ciona intestinalis	60.19	0.00e+00	642.00
IUUC-Csv-026367	Ciona savignyi	59.20	0.00e+00	650.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	65.34	4.00e-139	488.00
IUUC-Cne-027069	Cryptococcus neoformans	55.09	2.00e-127	448.00
IUUC-Cme-027233	Cyanidioschyzon merolae	29.88	1.00e-34	140.00
IUUC-Dre-028260	Danio rerio	79.46	0.00e+00	856.00
IUUC-Dno-029112	Dasypus novemcinctus	97.28	0.00e+00	1046.00
IUUC-Dor-031118	Dipodomys ordii	94.39	0.00e+00	801.00
IUUC-Dse-031493	Dothistroma septosporum	46.20	7.00e-125	440.00
IUUC-Dme-032138	Drosophila melanogaster	57.84	1.00e-171	596.00
IUUC-Ete-032411	Echinops telfairi	83.79	0.00e+00	832.00
IUUC-Eeu-035249	Erinaceus europaeus	82.93	0.00e+00	675.00
IUUC-Fca-036358	Felis catus	96.89	0.00e+00	1048.00
IUUC-Fal-036933	Ficedula albicollis	89.73	0.00e+00	971.00
IUUC-Fox-037713	Fusarium oxysporum	56.03	9.00e-139	486.00
IUUC-Fso-038380	Fusarium solani	63.16	5.00e-138	484.00
IUUC-Gmo-039133	Gadus morhua	79.53	0.00e+00	847.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.06	7.00e-132	463.00
IUUC-Gga-041176	Gallus gallus	88.95	0.00e+00	971.00
IUUC-Gac-042344	Gasterosteus aculeatus	77.52	0.00e+00	848.00
IUUC-Gma-043328	Glycine max	49.51	1.00e-131	462.00
IUUC-Ggo-044478	Gorilla gorilla	94.95	0.00e+00	1025.00
IUUC-Hsa-046037	Homo sapiens	95.15	0.00e+00	1026.00
IUUC-Hvu-047349	Hordeum vulgare	49.90	1.00e-131	462.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	96.12	0.00e+00	1040.00
IUUC-Kpa-049343	Komagataella pastoris	58.15	2.00e-118	419.00
IUUC-Lch-049830	Latimeria chalumnae	84.50	0.00e+00	914.00
IUUC-Lpe-051442	Leersia perrieri	56.00	3.00e-129	454.00
IUUC-Loc-051794	Lepisosteus oculatus	82.49	0.00e+00	866.00
IUUC-Lma-053137	Leptosphaeria maculans	45.33	5.00e-126	444.00
IUUC-Laf-053471	Loxodonta africana	96.10	0.00e+00	1033.00
IUUC-Mcc-055627	Macaca mulatta	94.95	0.00e+00	1026.00
IUUC-Meu-056148	Macropus eugenii	81.25	0.00e+00	868.00
IUUC-Mor-056960	Magnaporthe oryzae	65.95	7.00e-137	480.00
IUUC-Mtr-057816	Medicago truncatula	48.44	2.00e-127	449.00
IUUC-Mla-059031	Melampsora laricipopulina	65.09	7.00e-127	446.00
IUUC-Mga-059337	Meleagris gallopavo	89.30	0.00e+00	972.00
IUUC-Mvi-060217	Microbotryum violaceum	64.47	2.00e-129	456.00
IUUC-Mmr-061018	Microcebus murinus	96.50	0.00e+00	1045.00
IUUC-Mdo-062863	Monodelphis domestica	91.28	0.00e+00	962.00
IUUC-Mmu-063988	Mus musculus	94.17	0.00e+00	1011.00
IUUC-Mac-064459	Musa acuminata	48.30	9.00e-123	433.00
IUUC-Mpu-066559	Mustela putorius furo	97.67	0.00e+00	1055.00
IUUC-Mlu-067361	Myotis lucifugus	96.48	0.00e+00	1005.00
IUUC-Nfi-068492	Neosartorya fischeri	64.63	6.00e-129	454.00
IUUC-Ncr-068808	Neurospora crassa	57.11	2.00e-137	482.00
IUUC-Nle-069875	Nomascus leucogenys	95.34	0.00e+00	1029.00
IUUC-Opr-070462	Ochotona princeps	97.74	6.00e-158	550.00
IUUC-Ont-071365	Oreochromis niloticus	77.71	0.00e+00	848.00
IUUC-Oan-072708	Ornithorhynchus anatinus	91.25	0.00e+00	991.00
IUUC-Ocu-074594	Oryctolagus cuniculus	95.34	0.00e+00	1032.00
IUUC-Oba-075570	Oryza barthii	59.10	2.00e-127	449.00
IUUC-Obr-076366	Oryza brachyantha	64.41	4.00e-92	330.00
IUUC-Ogl-077153	Oryza glaberrima	59.10	6.00e-127	447.00
IUUC-Ogu-078540	Oryza glumaepatula	59.10	1.00e-127	449.00
IUUC-Oin-079612	Oryza indica	58.29	8.00e-126	443.00
IUUC-Olo-081077	Oryza longistaminata	58.29	8.00e-126	443.00
IUUC-Ome-081236	Oryza meridionalis	60.95	8.00e-125	440.00
IUUC-Oni-082499	Oryza nivara	59.10	1.00e-127	449.00
IUUC-Opu-083499	Oryza punctata	58.29	1.00e-125	442.00
IUUC-Oru-084276	Oryza rufipogon	59.10	1.00e-127	449.00
IUUC-Osa-085849	Oryza sativa	59.10	1.00e-127	449.00
IUUC-Ola-086655	Oryzias latipes	76.02	0.00e+00	829.00
IUUC-Olu-087637	Ostreococcus lucimarinus	57.77	6.00e-120	423.00
IUUC-Oga-087934	Otolemur garnettii	95.93	0.00e+00	1036.00
IUUC-Oar-090185	Ovis aries	95.54	0.00e+00	1026.00
IUUC-Ptr-091198	Pan troglodytes	95.34	0.00e+00	1029.00
IUUC-Pan-092622	Papio anubis	95.15	0.00e+00	1028.00
IUUC-Psi-093320	Pelodiscus sinensis	89.56	0.00e+00	973.00
IUUC-Pma-094638	Petromyzon marinus	76.89	0.00e+00	848.00
IUUC-Pno-094826	Phaeosphaeria nodorum	50.44	2.00e-104	372.00
IUUC-Ppa-095576	Physcomitrella patens	63.67	5.00e-124	437.00
IUUC-Pfo-096894	Poecilia formosa	77.80	0.00e+00	845.00
IUUC-Pab-098020	Pongo abelii	95.53	0.00e+00	1031.00
IUUC-Pop-099180	Populus trichocarpa	49.31	4.00e-128	451.00
IUUC-Pca-100909	Procavia capensis	90.05	0.00e+00	821.00
IUUC-Ppe-101346	Prunus persica	46.94	8.00e-126	443.00
IUUC-Pva-102167	Pteropus vampyrus	79.22	0.00e+00	807.00
IUUC-Pgr-103516	Puccinia graminis	50.52	1.00e-129	456.00
IUUC-Ptt-103738	Puccinia triticina	50.10	7.00e-131	460.00
IUUC-Pte-104352	Pyrenophora teres	57.60	2.00e-130	459.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	58.19	2.00e-131	462.00
IUUC-Rno-105291	Rattus norvegicus	94.76	0.00e+00	1022.00
IUUC-Sce-106204	Saccharomyces cerevisiae	49.85	2.00e-103	369.00
IUUC-Sha-106943	Sarcophilus harrisii	90.14	0.00e+00	951.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	64.76	2.00e-129	455.00
IUUC-Spo-108049	Schizosaccharomyces pombe	64.01	1.00e-134	472.00
IUUC-Smo-109043	Selaginella moellendorffii	60.18	5.00e-125	440.00
IUUC-Sit-110431	Setaria italica	57.87	3.00e-132	464.00
IUUC-Sly-111391	Solanum lycopersicum	49.06	1.00e-119	423.00
IUUC-Stu-112364	Solanum tuberosum	54.93	1.00e-95	342.00
IUUC-Sar-113450	Sorex araneus	98.28	0.00e+00	721.00
IUUC-Sbi-113829	Sorghum bicolor	49.39	7.00e-131	460.00
IUUC-Sre-115153	Sporisorium reilianum	61.49	3.00e-121	428.00
IUUC-Ssc-115798	Sus scrofa	97.09	0.00e+00	1043.00
IUUC-Tgu-117417	Taeniopygia guttata	90.25	0.00e+00	974.00
IUUC-Tru-117615	Takifugu rubripes	75.83	0.00e+00	789.00
IUUC-Tsy-119480	Tarsius syrichta	96.29	0.00e+00	1029.00
IUUC-Tni-119847	Tetraodon nigroviridis	75.58	0.00e+00	820.00
IUUC-Tca-121287	Theobroma cacao	47.03	6.00e-127	447.00
IUUC-Tre-122010	Trichoderma reesei	64.62	2.00e-142	498.00
IUUC-Tvi-122475	Trichoderma virens	63.45	6.00e-141	493.00
IUUC-Tae-124397	Triticum aestivum	49.70	3.00e-133	468.00
IUUC-Tur-126116	Triticum urartu	50.13	9.00e-101	360.00
IUUC-Tme-126992	Tuber melanosporum	64.94	7.00e-136	477.00
IUUC-Tbe-127803	Tupaia belangeri	84.58	0.00e+00	739.00
IUUC-Ttr-128933	Tursiops truncatus	97.48	0.00e+00	1045.00
IUUC-Uma-129447	Ustilago maydis	59.38	2.00e-117	415.00
IUUC-Vda-129780	Verticillium dahliae	62.94	4.00e-137	481.00
IUUC-Vpa-130557	Vicugna pacos	92.17	8.00e-124	437.00
IUUC-Vvi-130918	Vitis vinifera	47.45	4.00e-122	431.00
IUUC-Xtr-132409	Xenopus tropicalis	85.49	0.00e+00	888.00
IUUC-Xma-133420	Xiphophorus maculatus	77.91	0.00e+00	851.00
IUUC-Yli-134362	Yarrowia lipolytica	51.12	2.00e-121	428.00
IUUC-Zma-135804	Zea mays	58.56	6.00e-126	444.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence