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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Dme-031645
UUCD1 version UUC-DrM-00585
Ensembl Protein ID FBpp0073354
UniProt Accession Q9VYY3; B4F5S5; B4F5S6; B4F5S7; B4F5S8; B4F5S9; B4F5T0; B4F5T1; B4F5T3; C0MLQ2; C0MLQ9; C0MLR0; Q8SYN2; UBA5_DROME
Genbank Protein ID CAQ53523.1; CAQ53524.1; CAQ53525.1; CAQ53526.1; CAQ53527.1; CAQ53528.1; CAQ53529.1; CAQ53530.1; CAQ53531.1; CAQ53532.1; CAR94199.1; CAR94200.1; CAR94201.1; CAR94202.1; CAR94203.1; CAR94204.1; CAR94205.1; CAR94206.1; CAR94207.1; CAR94208.1; CAR94209.1; CAR94210.1; AAF48050.1; AAL49051.1
Protein Name Ubiquitin-like modifier-activating enzyme 5
Genbank Nucleotide ID AM999161; AM999162; AM999163; AM999164; AM999165; AM999166; AM999167; AM999168; AM999169; AM999170; FM246273; FM246274; FM246275; FM246276; FM246277; FM246278; FM246279; FM246280; FM246281; FM246282; FM246283; FM246284; AE014298; AY071429
Gene Name CG1749; Uba5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0030305 FBtr0073505 FBpp0073354
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNA
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
dbPAFPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E1 62.80 5.00e-128 455.00 IUUC-Hsa-046777
Active Site
Position(s) Description Evidence
250 Glycyl thioester intermediate {ECO:0000250}
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     E1-like enzyme which activates UFM1.
 E1-like enzyme which activates UFM1.
Protein Sequence
(Fasta)
MSHAIDELQA IIADLKTELE TEPKSSGGVA SNSRLARDRI DRMSAEVVDS NPYSRLMALQ 60
RMNIVKDYER IRYKAVAIVG VGGVGSVTAD MLTRCGIGKL ILFDYDKVEL ANMNRLFFTP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031645|E1,E1_ThiF|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAATTTGGCC ATCTGGCAGC ACTGGTCAAA AGTGACACGG CGACAACCAG CTTAAAAGCG 60
AAAGTTAACA ATTAACAATT GCTGGCGTCC ATAGCCAAAC ACACGAGCCA GAAACTGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031645|E1,E1_ThiF|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
Interpro

IPR029752--D-isomer_DH_CS1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
Pfam

PF00899--ThiF
Gene Ontology

GO:0005737--C:cytoplasm
GO:0019008--C:molybdopterin synthase complex
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0071566--F:UFM1 activating enzyme activity
GO:0031987--P:locomotion involved in locomotory behavior
GO:0071569--P:protein ufmylation
GO:0050808--P:synapse organization
KEGG dme:Dmel_CG1749
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001324 Ailuropoda melanoleuca 66.13 3.00e-130 457.00
IUUC-Atr-002660 Amborella trichopoda 58.73 2.00e-113 401.00
IUUC-Apl-003722 Anas platyrhynchos 68.90 3.00e-118 417.00
IUUC-Aca-004584 Anolis carolinensis 66.95 3.00e-127 447.00
IUUC-Aly-005881 Arabidopsis lyrata 58.45 5.00e-109 387.00
IUUC-Ath-007286 Arabidopsis thaliana 61.16 5.00e-113 400.00
IUUC-Ame-011679 Astyanax mexicanus 63.26 8.00e-107 379.00
IUUC-Bta-012517 Bos taurus 66.40 2.00e-134 471.00
IUUC-Bdi-014894 Brachypodium distachyon 63.08 1.00e-109 389.00
IUUC-Bol-016054 Brassica oleracea 61.36 4.00e-112 397.00
IUUC-Bra-016708 Brassica rapa 60.98 2.00e-112 398.00
IUUC-Cel-018424 Caenorhabditis elegans 65.55 7.00e-127 446.00
IUUC-Cja-019825 Callithrix jacchus 71.59 6.00e-106 375.00
IUUC-Cfa-021160 Canis familiaris 62.53 2.00e-132 464.00
IUUC-Cpo-022255 Cavia porcellus 67.39 3.00e-134 470.00
IUUC-Csa-023827 Chlorocebus sabaeus 63.02 1.00e-136 478.00
IUUC-Cho-025078 Choloepus hoffmanni 64.52 9.00e-129 452.00
IUUC-Cin-025217 Ciona intestinalis 63.24 9.00e-129 452.00
IUUC-Dre-027578 Danio rerio 62.07 7.00e-131 459.00
IUUC-Dno-029330 Dasypus novemcinctus 64.69 3.00e-127 447.00
IUUC-Dor-030425 Dipodomys ordii 60.69 2.00e-82 298.00
IUUC-Ete-032912 Echinops telfairi 82.29 3.00e-35 141.00
IUUC-Eca-033247 Equus caballus 66.40 1.00e-130 458.00
IUUC-Eeu-034472 Erinaceus europaeus 65.35 1.00e-121 428.00
IUUC-Fca-035684 Felis catus 66.93 2.00e-133 467.00
IUUC-Fal-037654 Ficedula albicollis 65.24 3.00e-124 437.00
IUUC-Gmo-039449 Gadus morhua 54.50 2.00e-99 355.00
IUUC-Gga-041051 Gallus gallus 65.50 3.00e-127 447.00
IUUC-Gac-042325 Gasterosteus aculeatus 64.11 3.00e-136 477.00
IUUC-Gma-043136 Glycine max 55.56 3.00e-117 414.00
IUUC-Ggo-044414 Gorilla gorilla 61.93 3.00e-134 471.00
IUUC-Hsa-046777 Homo sapiens 63.70 1.00e-134 471.00
IUUC-Hvu-047549 Hordeum vulgare 61.65 1.00e-94 338.00
IUUC-Itr-048175 Ictidomys tridecemlineatus 65.51 1.00e-131 461.00
IUUC-Lch-050142 Latimeria chalumnae 63.92 1.00e-135 475.00
IUUC-Lpe-050769 Leersia perrieri 64.46 4.00e-98 350.00
IUUC-Loc-052405 Lepisosteus oculatus 68.12 3.00e-126 444.00
IUUC-Laf-054152 Loxodonta africana 62.29 5.00e-133 466.00
IUUC-Mcc-055618 Macaca mulatta 65.63 2.00e-122 431.00
IUUC-Meu-056486 Macropus eugenii 70.29 2.00e-126 444.00
IUUC-Mtr-057871 Medicago truncatula 58.58 3.00e-114 404.00
IUUC-Mga-059284 Meleagris gallopavo 65.50 1.00e-127 448.00
IUUC-Mmr-061242 Microcebus murinus 63.87 1.00e-133 468.00
IUUC-Mdo-063034 Monodelphis domestica 68.11 2.00e-132 464.00
IUUC-Mmu-064322 Mus musculus 64.40 8.00e-133 466.00
IUUC-Mac-065128 Musa acuminata 63.59 7.00e-63 238.00
IUUC-Mpu-066438 Mustela putorius furo 65.17 1.00e-130 458.00
IUUC-Mlu-067578 Myotis lucifugus 66.40 1.00e-130 458.00
IUUC-Nle-069542 Nomascus leucogenys 64.78 2.00e-132 464.00
IUUC-Opr-070710 Ochotona princeps 61.52 7.00e-127 446.00
IUUC-Ont-072067 Oreochromis niloticus 69.34 1.00e-130 458.00
IUUC-Oan-073593 Ornithorhynchus anatinus 65.18 2.00e-126 444.00
IUUC-Ocu-073964 Oryctolagus cuniculus 59.56 1.00e-124 439.00
IUUC-Oba-075476 Oryza barthii 62.61 2.00e-112 398.00
IUUC-Obr-076517 Oryza brachyantha 63.86 4.00e-111 394.00
IUUC-Ogu-078664 Oryza glumaepatula 62.92 9.00e-113 399.00
IUUC-Olo-081012 Oryza longistaminata 62.61 2.00e-112 398.00
IUUC-Ome-081129 Oryza meridionalis 62.61 2.00e-112 398.00
IUUC-Oni-082265 Oryza nivara 62.65 4.00e-110 390.00
IUUC-Opu-084121 Oryza punctata 64.06 3.00e-111 394.00
IUUC-Oru-084451 Oryza rufipogon 61.94 6.00e-97 347.00
IUUC-Osa-086132 Oryza sativa 62.61 2.00e-112 398.00
IUUC-Ola-086842 Oryzias latipes 66.85 1.00e-129 455.00
IUUC-Oga-088160 Otolemur garnettii 67.65 4.00e-131 460.00
IUUC-Oar-089362 Ovis aries 66.40 1.00e-134 472.00
IUUC-Ptr-091256 Pan troglodytes 62.74 6.00e-135 473.00
IUUC-Pan-092913 Papio anubis 62.89 3.00e-129 454.00
IUUC-Psi-093740 Pelodiscus sinensis 67.08 7.00e-117 412.00
IUUC-Pma-094485 Petromyzon marinus 75.78 2.00e-93 333.00
IUUC-Ppa-095673 Physcomitrella patens 62.31 4.00e-109 387.00
IUUC-Pfo-096196 Poecilia formosa 68.18 9.00e-133 465.00
IUUC-Pab-098449 Pongo abelii 62.47 2.00e-135 474.00
IUUC-Pop-099049 Populus trichocarpa 53.41 1.00e-109 389.00
IUUC-Pca-100917 Procavia capensis 59.59 1.00e-77 282.00
IUUC-Ppe-101797 Prunus persica 57.83 1.00e-117 415.00
IUUC-Pva-102852 Pteropus vampyrus 66.67 1.00e-131 462.00
IUUC-Rno-105213 Rattus norvegicus 65.09 2.00e-134 471.00
IUUC-Sha-107569 Sarcophilus harrisii 66.22 2.00e-132 464.00
IUUC-Smo-109146 Selaginella moellendorffii 54.86 3.00e-108 384.00
IUUC-Sit-109794 Setaria italica 61.11 8.00e-113 399.00
IUUC-Sly-111622 Solanum lycopersicum 64.89 9.00e-114 402.00
IUUC-Stu-112522 Solanum tuberosum 65.30 1.00e-113 402.00
IUUC-Sar-113045 Sorex araneus 56.16 1.00e-113 402.00
IUUC-Sbi-113861 Sorghum bicolor 57.80 1.00e-112 398.00
IUUC-Ssc-115290 Sus scrofa 63.14 5.00e-107 379.00
IUUC-Tgu-117125 Taeniopygia guttata 69.01 6.00e-126 442.00
IUUC-Tru-118041 Takifugu rubripes 66.75 3.00e-133 467.00
IUUC-Tsy-119300 Tarsius syrichta 59.38 6.00e-101 359.00
IUUC-Tni-120310 Tetraodon nigroviridis 64.29 3.00e-126 444.00
IUUC-Tca-121405 Theobroma cacao 54.24 1.00e-112 398.00
IUUC-Tae-123656 Triticum aestivum 61.02 2.00e-112 397.00
IUUC-Tur-125985 Triticum urartu 60.91 2.00e-112 397.00
IUUC-Tbe-127478 Tupaia belangeri 74.37 8.00e-115 405.00
IUUC-Ttr-128169 Tursiops truncatus 71.48 3.00e-104 370.00
IUUC-Vpa-130508 Vicugna pacos 60.50 1.00e-106 379.00
IUUC-Vvi-131252 Vitis vinifera 55.10 4.00e-111 394.00
IUUC-Xtr-132776 Xenopus tropicalis 65.69 1.00e-132 464.00
IUUC-Xma-133110 Xiphophorus maculatus 68.18 2.00e-134 471.00
Created Date 25-Jun-2017

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