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Tag Content
iUUCD ID IUUC-Mpu-065749
Ensembl Protein ID ENSMPUP00000010954.1
UniProt Accession M3YHZ7; M3YHZ7_MUSPF
Genbank Protein ID ENSMPUP00000010954
Protein Name Inhibitor of growth protein
Genbank Nucleotide ID AEYP01043853
Gene Name ING2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMPUG00000011044.1 ENSMPUT00000011137.1 ENSMPUP00000010954.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 3.20e-09 36.9 172 218
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
    ++C +C + + +e ++ C++ C ewfH+ C++l+ +p+ + w+CpkCr
   Q: 172 TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 218
    69*.*******99..*****999*99***********...888886.******8 PP
   

Organism Mustela putorius furo
Protein Sequence
(Fasta)
MQRNVSVLRE LDNKYQETLK EIDDVYEKYK KEDDSNQKKR LQQHLQRALI NSQELGDEKI 60
QIVTQMLELV ENRARQMELH SQCFQDPAEG ERASDKAKMD SSQPERSSRR PRRQRTSESR 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mpu-065749|E3,PHD|Mustela putorius furo
Please wait for a moment...
Nucleotide Sequence
(Fasta)
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNAG CAACTGTACT CGTCGGCCGC GCTCCTGACC GGGGAGCGGA GCCGGCTCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mpu-065749|E3,PHD|Mustela putorius furo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002213 Ailuropoda melanoleuca 99.58 4.00e-102 363.00
IUUC-Apl-003705 Anas platyrhynchos 88.79 9.00e-92 329.00
IUUC-Aca-004990 Anolis carolinensis 81.17 1.00e-88 319.00
IUUC-Ame-011426 Astyanax mexicanus 69.60 7.00e-74 270.00
IUUC-Bta-012721 Bos taurus 97.49 1.00e-99 355.00
IUUC-Cja-018960 Callithrix jacchus 97.07 6.00e-90 323.00
IUUC-Cfa-020869 Canis familiaris 99.16 2.00e-101 362.00
IUUC-Cpo-021414 Cavia porcellus 96.23 2.00e-98 351.00
IUUC-Csa-023304 Chlorocebus sabaeus 97.07 3.00e-90 324.00
IUUC-Dre-028562 Danio rerio 69.35 5.00e-81 293.00
IUUC-Dno-029945 Dasypus novemcinctus 97.07 3.00e-99 354.00
IUUC-Dor-030141 Dipodomys ordii 96.23 5.00e-97 347.00
IUUC-Ete-032709 Echinops telfairi 95.40 3.00e-107 381.00
IUUC-Eca-033432 Equus caballus 97.91 1.00e-99 355.00
IUUC-Eeu-035285 Erinaceus europaeus 97.56 4.00e-90 323.00
IUUC-Fca-036467 Felis catus 99.16 3.00e-101 361.00
IUUC-Fal-036700 Ficedula albicollis 87.56 5.00e-91 327.00
IUUC-Gmo-038748 Gadus morhua 62.55 6.00e-76 276.00
IUUC-Gga-040175 Gallus gallus 88.34 2.00e-91 328.00
IUUC-Gac-041403 Gasterosteus aculeatus 64.66 6.00e-81 293.00
IUUC-Hsa-045837 Homo sapiens 97.07 3.00e-90 324.00
IUUC-Itr-049062 Ictidomys tridecemlineatus 97.49 4.00e-99 353.00
IUUC-Lch-049965 Latimeria chalumnae 81.59 6.00e-91 326.00
IUUC-Laf-053353 Loxodonta africana 95.56 2.00e-99 354.00
IUUC-Mcc-055155 Macaca mulatta 97.13 7.00e-72 262.00
IUUC-Meu-056470 Macropus eugenii 92.05 2.00e-101 362.00
IUUC-Mga-059570 Meleagris gallopavo 88.34 7.00e-91 326.00
IUUC-Mmr-061385 Microcebus murinus 97.49 1.00e-90 326.00
IUUC-Mdo-062144 Monodelphis domestica 92.47 6.00e-102 363.00
IUUC-Mmu-063215 Mus musculus 96.23 9.00e-99 352.00
IUUC-Nle-069968 Nomascus leucogenys 96.84 2.00e-80 291.00
IUUC-Ont-071524 Oreochromis niloticus 66.53 7.00e-78 283.00
IUUC-Ocu-074870 Oryctolagus cuniculus 98.33 3.00e-100 357.00
IUUC-Ola-087400 Oryzias latipes 89.02 3.00e-44 171.00
IUUC-Oga-088336 Otolemur garnettii 97.07 3.00e-90 324.00
IUUC-Oar-090136 Ovis aries 97.07 3.00e-99 354.00
IUUC-Ptr-091348 Pan troglodytes 97.37 3.00e-81 294.00
IUUC-Pan-092819 Papio anubis 97.07 3.00e-90 324.00
IUUC-Psi-093854 Pelodiscus sinensis 85.63 3.00e-62 230.00
IUUC-Pfo-096633 Poecilia formosa 66.67 1.00e-71 263.00
IUUC-Pab-098346 Pongo abelii 97.07 4.00e-90 324.00
IUUC-Pca-100278 Procavia capensis 94.56 2.00e-106 377.00
IUUC-Pva-103190 Pteropus vampyrus 98.33 4.00e-100 357.00
IUUC-Rno-104940 Rattus norvegicus 95.82 1.00e-97 348.00
IUUC-Sha-107533 Sarcophilus harrisii 92.05 1.00e-102 365.00
IUUC-Sar-113630 Sorex araneus 96.59 1.00e-90 325.00
IUUC-Ssc-115734 Sus scrofa 98.33 5.00e-100 357.00
IUUC-Tgu-117034 Taeniopygia guttata 88.00 1.00e-91 328.00
IUUC-Tru-118168 Takifugu rubripes 61.45 9.00e-72 263.00
IUUC-Tsy-119494 Tarsius syrichta 97.89 9.00e-82 296.00
IUUC-Tni-120100 Tetraodon nigroviridis 62.61 5.00e-68 250.00
IUUC-Ttr-128442 Tursiops truncatus 97.56 3.00e-90 323.00
IUUC-Vpa-130063 Vicugna pacos 97.49 1.00e-99 355.00
Created Date 25-Jun-2017

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