iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073706

UUCD1 version

UUC-OrA-00467

Ensembl Protein ID

ENSOANP00000009814.2

UniProt Accession

F7CG66; F7CG66_ORNAN

Protein Name

Uncharacterized protein

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006145.3	ENSOANT00000009815.3	ENSOANP00000009814.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.00e-24	85.7	404	474
E3 adaptor/Cullin RING/DCX/DWD	2.10e-37	125.7	52	83
UBD/Beta-Prp	8.60e-51	173.1	6	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
           +p+eflCpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e++
   Q: 404  IPDEFLCPITRELMKDPVIAADGYSYEKEAMENWFSKKKRTSPMTNLVLPSLILTPNRTLKMAINRWLETQ 474
           8*******************************************************************987 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gHt  v+c++f ++ ++l+s+s Dgt  +W+ 
   Q: 52   GHTYAVHCCRFsPSgHILASCSTDGTTVLWSS 83
           8***********666999************85 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvht 89
            t+ +h ++v +  +f  ++sllat s d+ti+++++ +      + l+gh+ +v +++fsp+g il+++s+D+t  +w+ ++g+++ +
   Q: 6    HTITDHGDDVNY-CAF--SSSLLATCSLDKTIRLYSLGDFAElpHSPLKGHTYAVHCCRFSPSGHILASCSTDGTTVLWSSQNGQTLAI 91
           445555555555.555..67777777777777777776644455566677777777777777777777777777777777777777777 PP
   S: 90   lkghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           +++ + + v+ + fsp++  lvsG++d t+ +w+++t++  +   s++dg+    +++p+gnl+v+Gs  + + +Wd k+ + l+  + 
   Q: 92   MEQPSgSPVRICCFSPDSTCLVSGGADGTVVLWNTHTYKLQR-SGSVKDGSLVACAFSPNGNLFVTGSSCGDLTVWDDKMRC-LYSEKA 178
           775441457777777777777777777777777777776666.777777777777777777777777777777777765443.333333 PP
   S: 178  ghtdsvyslsfdsng..........kelvsgsldgtvklwdl 209
            h+  +++ +f+s+           ++++s+++d + klw +
   Q: 179  -HDLGITCCDFSSQPvsdgdqgpnfFRMASCGQDCQTKLWVI 219
           .77777777776666666677777777777777777777755 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MVTLIHTITD HGDDVNYCAF SSSLLATCSL DKTIRLYSLG DFAELPHSPL KGHTYAVHCC 60
RFSPSGHILA SCSTDGTTVL WSSQNGQTLA IMEQPSGSPV RICCFSPDST CLVSGGADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTTTTTT TACCCATTCC CTTTATTTCT TAAAAAAATT TACAGGTCAT CTTACTTGAA 60
AATGGTGACA CTAATTCACA CCATCACAGA TCATGGCGAT GATGTCAACT ACTGTGCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00536--SAM_1
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

oaa:100081746

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000612	Aegilops tauschii	53.73	2.00e-17	84.30
IUUC-Aml-001614	Ailuropoda melanoleuca	83.16	0.00e+00	837.00
IUUC-Apl-003529	Anas platyrhynchos	76.21	0.00e+00	769.00
IUUC-Aca-004257	Anolis carolinensis	70.31	0.00e+00	698.00
IUUC-Ame-011357	Astyanax mexicanus	50.31	3.00e-114	404.00
IUUC-Bta-013032	Bos taurus	80.47	0.00e+00	801.00
IUUC-Cja-018743	Callithrix jacchus	82.11	0.00e+00	825.00
IUUC-Cfa-021197	Canis familiaris	82.11	0.00e+00	832.00
IUUC-Cpo-022279	Cavia porcellus	81.89	0.00e+00	827.00
IUUC-Csa-023954	Chlorocebus sabaeus	83.16	0.00e+00	832.00
IUUC-Cho-025083	Choloepus hoffmanni	66.84	2.00e-143	501.00
IUUC-Cin-025786	Ciona intestinalis	35.43	1.00e-82	299.00
IUUC-Dre-028087	Danio rerio	56.73	5.00e-146	510.00
IUUC-Dno-028919	Dasypus novemcinctus	83.16	0.00e+00	831.00
IUUC-Dor-031112	Dipodomys ordii	79.16	0.00e+00	797.00
IUUC-Ete-032405	Echinops telfairi	81.23	6.00e-169	585.00
IUUC-Eca-033254	Equus caballus	81.26	0.00e+00	820.00
IUUC-Eeu-034545	Erinaceus europaeus	78.32	0.00e+00	763.00
IUUC-Fca-035482	Felis catus	83.58	0.00e+00	837.00
IUUC-Fal-036976	Ficedula albicollis	61.65	6.00e-166	576.00
IUUC-Gmo-039213	Gadus morhua	53.81	1.00e-136	479.00
IUUC-Gga-040561	Gallus gallus	75.00	0.00e+00	757.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.42	9.00e-139	486.00
IUUC-Ggo-045503	Gorilla gorilla	82.95	0.00e+00	831.00
IUUC-Hsa-045910	Homo sapiens	83.16	0.00e+00	833.00
IUUC-Hvu-047757	Hordeum vulgare	45.05	7.00e-19	89.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	81.70	0.00e+00	648.00
IUUC-Loc-052307	Lepisosteus oculatus	58.66	6.00e-170	589.00
IUUC-Laf-053587	Loxodonta africana	82.95	0.00e+00	831.00
IUUC-Mcc-055679	Macaca mulatta	82.95	0.00e+00	830.00
IUUC-Meu-055962	Macropus eugenii	70.11	0.00e+00	644.00
IUUC-Mga-059652	Meleagris gallopavo	74.58	0.00e+00	758.00
IUUC-Mmr-060943	Microcebus murinus	81.55	0.00e+00	807.00
IUUC-Mdo-062592	Monodelphis domestica	84.10	0.00e+00	836.00
IUUC-Mmu-063577	Mus musculus	76.84	0.00e+00	764.00
IUUC-Mpu-066422	Mustela putorius furo	82.11	0.00e+00	825.00
IUUC-Mlu-067250	Myotis lucifugus	81.89	0.00e+00	818.00
IUUC-Nle-069517	Nomascus leucogenys	82.74	0.00e+00	829.00
IUUC-Opr-070776	Ochotona princeps	82.53	0.00e+00	821.00
IUUC-Ont-071821	Oreochromis niloticus	57.38	2.00e-149	521.00
IUUC-Ocu-074766	Oryctolagus cuniculus	74.32	0.00e+00	721.00
IUUC-Obr-076354	Oryza brachyantha	51.35	8.00e-20	90.90
IUUC-Ola-086531	Oryzias latipes	56.26	5.00e-145	506.00
IUUC-Oga-088388	Otolemur garnettii	80.21	0.00e+00	809.00
IUUC-Oar-089748	Ovis aries	81.32	0.00e+00	803.00
IUUC-Ptr-090616	Pan troglodytes	82.84	0.00e+00	825.00
IUUC-Pan-091769	Papio anubis	82.75	4.00e-172	596.00
IUUC-Psi-093334	Pelodiscus sinensis	81.68	0.00e+00	767.00
IUUC-Pma-094383	Petromyzon marinus	48.34	2.00e-129	454.00
IUUC-Pfo-096801	Poecilia formosa	55.28	4.00e-146	510.00
IUUC-Pab-098139	Pongo abelii	81.65	0.00e+00	671.00
IUUC-Pca-100523	Procavia capensis	69.68	0.00e+00	676.00
IUUC-Pva-102286	Pteropus vampyrus	80.84	0.00e+00	784.00
IUUC-Rno-104831	Rattus norvegicus	77.47	0.00e+00	780.00
IUUC-Sha-107499	Sarcophilus harrisii	85.89	0.00e+00	852.00
IUUC-Sar-113389	Sorex araneus	80.00	0.00e+00	772.00
IUUC-Tgu-116769	Taeniopygia guttata	72.42	0.00e+00	728.00
IUUC-Tru-118774	Takifugu rubripes	53.29	4.00e-137	480.00
IUUC-Tsy-119595	Tarsius syrichta	73.24	1.00e-169	588.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.14	2.00e-145	508.00
IUUC-Tur-126683	Triticum urartu	52.24	3.00e-17	83.60
IUUC-Tbe-127938	Tupaia belangeri	75.33	3.00e-134	470.00
IUUC-Ttr-128193	Tursiops truncatus	82.08	0.00e+00	699.00
IUUC-Vpa-130275	Vicugna pacos	82.74	0.00e+00	821.00
IUUC-Xtr-131982	Xenopus tropicalis	62.74	1.00e-171	595.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence