iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062167

UUCD1 version

UUC-MoD-01139

Ensembl Protein ID

ENSMODP00000005851.2

UniProt Accession

F6XIH7; F6XIH7_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004750.2	ENSMODT00000005974.2	ENSMODP00000005851.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-86	290.4	452	867

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCYmNSv+Q+L++ +++r+++l+     l+e    +++++l+++lq lf+ l +s++ avsp+++l+a +   + fs  +qq
   Q: 452  GLINLGNTCYMNSVIQALFMASDFRHCVLH-----LPE----DNSQPLMTKLQWLFAFLEHSQRPAVSPESFLSASW--TPWFSPGAQQ 529
           9*****************************.....554....34689***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k++++ + ++++++ +++ i+++F+g++ ++i+cl+c nvs+ree f+dlsl++p  
   Q: 530  DCSEYLKYLLDRLHEEE-----KTGKRICQKLKQSSTPSPSDEQPNLSPTAIEKMFGGKIVTRIRCLRCLNVSTREEAFTDLSLAFPPP 613
           *****************.....667777777778888888899********************************************88 PP
   S: 180  eetkke...................................................................slqdcLesftkeeele 201
           + +  +                                                                   s+ d+L+ f ++e+l+
   Q: 614  DRRRRRlgsvmlpvedirvqgtpspaktqamgsegsrrqrkhciagdalpplvnieilgfqepgqmcgpegsrSVPDLLNYFLSPETLT 702
           87766689********************************************************************************* PP
   S: 202  genkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp..fctspeekqkekkkYeLiavvvHsG 288
            en+y+ce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki ++v++pl L l     c +++++q  +  Y+L++vvvHsG
   Q: 703  AENRYHCEHCASLQDAEKVVELSEGPRYLILTLLRFSFDLRTMRRKKILDNVSIPLFLRLPVggGCPQQDQGQ-ACAAYDLCSVVVHSG 790
           *******************************************************998888542666655555.6************** PP
   S: 289  .slssGHYvayvkn......................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
            s++sGHY++y+++                       + +W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 791  iSSESGHYYCYAREgatarvnparspglspaeklsgLESQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 867
           **************99999999999999888877777999*******************999************985 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

PGQGAAMDKI LEAVMLSSYP TNVKQGLARR VIEAAKQPMD SAQCWAMLEL STKLYLMGDT 60
KFKREIGQEV LEVYGHYHLE AFVEFFNAHF LLTLLQEGYG TPGHPSPYVL DYVQLGLQFI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGGGCAAG GAGCAGCTAT GGACAAGATC CTGGAAGCCG TGATGCTGTC ATCCTACCCC 60
ACCAACGTGA AGCAAGGGCT GGCACGGCGG GTGATCGAGG CAGCAAAGCA GCCCATGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	79.93	0.00e+00	843.00
IUUC-Apl-004121	Anas platyrhynchos	72.03	0.00e+00	1292.00
IUUC-Aca-005070	Anolis carolinensis	63.33	0.00e+00	827.00
IUUC-Bta-012545	Bos taurus	74.44	0.00e+00	971.00
IUUC-Cja-019731	Callithrix jacchus	75.00	0.00e+00	969.00
IUUC-Cfa-020095	Canis familiaris	75.89	0.00e+00	989.00
IUUC-Cpo-021961	Cavia porcellus	72.52	0.00e+00	1095.00
IUUC-Csa-023167	Chlorocebus sabaeus	71.92	0.00e+00	1153.00
IUUC-Dor-030538	Dipodomys ordii	76.26	0.00e+00	803.00
IUUC-Eeu-035120	Erinaceus europaeus	57.82	0.00e+00	688.00
IUUC-Fal-037625	Ficedula albicollis	72.27	0.00e+00	1330.00
IUUC-Gga-040767	Gallus gallus	71.81	0.00e+00	1342.00
IUUC-Ggo-045323	Gorilla gorilla	79.62	0.00e+00	807.00
IUUC-Hsa-046124	Homo sapiens	74.70	0.00e+00	955.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	72.81	0.00e+00	1242.00
IUUC-Lch-049513	Latimeria chalumnae	62.06	0.00e+00	1112.00
IUUC-Loc-052698	Lepisosteus oculatus	57.11	0.00e+00	1011.00
IUUC-Laf-053999	Loxodonta africana	72.46	0.00e+00	1256.00
IUUC-Mcc-055266	Macaca mulatta	73.59	0.00e+00	931.00
IUUC-Meu-056906	Macropus eugenii	95.98	0.00e+00	1295.00
IUUC-Mga-059595	Meleagris gallopavo	70.72	0.00e+00	1304.00
IUUC-Mmu-063298	Mus musculus	75.61	0.00e+00	965.00
IUUC-Mpu-066195	Mustela putorius furo	74.93	0.00e+00	967.00
IUUC-Opr-070454	Ochotona princeps	65.43	4.00e-117	416.00
IUUC-Ocu-074121	Oryctolagus cuniculus	68.02	0.00e+00	1068.00
IUUC-Oga-088593	Otolemur garnettii	73.36	0.00e+00	1212.00
IUUC-Oar-090140	Ovis aries	74.00	0.00e+00	956.00
IUUC-Pan-092168	Papio anubis	72.16	0.00e+00	1151.00
IUUC-Psi-093707	Pelodiscus sinensis	72.74	0.00e+00	1338.00
IUUC-Pab-097614	Pongo abelii	74.55	0.00e+00	957.00
IUUC-Pca-100683	Procavia capensis	71.06	0.00e+00	930.00
IUUC-Pva-103146	Pteropus vampyrus	65.68	0.00e+00	855.00
IUUC-Rno-105061	Rattus norvegicus	73.85	0.00e+00	963.00
IUUC-Sha-106686	Sarcophilus harrisii	94.24	0.00e+00	1281.00
IUUC-Tgu-117024	Taeniopygia guttata	73.40	0.00e+00	1352.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence