iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134595

Ensembl Protein ID

CAG78708

UniProt Accession

Q6C0B6; DCN1_YARLI

Genbank Protein ID

CAG78708.1

Protein Name

Defective in cullin neddylation protein 1

Genbank Nucleotide ID

CR382132

Gene Name

DCN1; YALI0F26147g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_F26147g	CAG78708	CAG78708

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/DCUN1	30.51	3.00e-29	125.00	IUUC-Ath-007531
UBD/Alpha-Helix/UBA	24.53	2.00e-20	95.90	IUUC-Cel-018441
E3 activity/DCUN1	32.51	8.00e-35	144.00	IUUC-Hsa-046089
UBD/Alpha-Helix/UBA	32.51	8.00e-35	144.00	IUUC-Hsa-046089
UBD/Alpha-Helix/UBA	32.51	2.00e-34	143.00	IUUC-Mmu-063954
E3 activity/DCUN1	24.31	9.00e-21	95.10	IUUC-Sce-106358
UBD/Alpha-Helix/UBA	24.31	9.00e-21	95.10	IUUC-Sce-106358

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Yarrowia lipolytica

Functional Description
(View)

May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).

Protein Sequence
(Fasta)

MVRSDWRAQE IRRVMTFTGS KEKTARDALE KFDWNVEVAI DHILNTPQVD LSGASKVFDK 60
YRNADSDEID LDGTIQYITD LGLSLEEPTV LAVAMTAGSP SVGTFTRKPF VEGWAAIGGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTACGAT CAGACTGGAG GGCGCAGGAA ATCAGAAGAG TCATGACGTT CACGGGGAGC 60
AAGGAGAAGA CAGCCCGTGA TGCCCTGGAA AAGTTTGACT GGAACGTCGA GGTGGCTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

KEGG

yli:YALI0F26147g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	33.20	3.00e-39	152.00
IUUC-Aml-001879	Ailuropoda melanoleuca	32.51	1.00e-36	144.00
IUUC-Atr-002662	Amborella trichopoda	39.58	1.00e-18	84.70
IUUC-Apl-003933	Anas platyrhynchos	32.78	2.00e-36	143.00
IUUC-Aca-005269	Anolis carolinensis	32.92	1.00e-36	144.00
IUUC-Aly-006285	Arabidopsis lyrata	30.74	1.00e-24	104.00
IUUC-Ath-007531	Arabidopsis thaliana	30.51	6.00e-31	125.00
IUUC-Ago-007806	Ashbya gossypii	28.12	1.00e-19	87.80
IUUC-Acl-008172	Aspergillus clavatus	28.68	2.00e-27	113.00
IUUC-Afl-008569	Aspergillus flavus	30.65	8.00e-34	135.00
IUUC-Afu-009005	Aspergillus fumigatus	29.78	2.00e-23	99.80
IUUC-Ani-009241	Aspergillus nidulans	25.61	2.00e-26	110.00
IUUC-Ang-009664	Aspergillus niger	30.33	6.00e-31	125.00
IUUC-Aor-009902	Aspergillus oryzae	28.70	1.00e-11	60.10
IUUC-Ate-010414	Aspergillus terreus	31.73	2.00e-34	137.00
IUUC-Ame-011763	Astyanax mexicanus	32.92	6.00e-38	148.00
IUUC-Bgr-011991	Blumeria graminis	30.30	2.00e-27	113.00
IUUC-Bta-013561	Bos taurus	31.78	2.00e-35	139.00
IUUC-Bci-013824	Botrytis cinerea	33.74	6.00e-36	142.00
IUUC-Bdi-014138	Brachypodium distachyon	34.30	1.00e-39	154.00
IUUC-Bol-016110	Brassica oleracea	31.91	1.00e-33	134.00
IUUC-Bra-017111	Brassica rapa	32.34	8.00e-34	134.00
IUUC-Cel-018441	Caenorhabditis elegans	24.53	5.00e-22	95.90
IUUC-Cja-019502	Callithrix jacchus	32.92	3.00e-37	146.00
IUUC-Cfa-020523	Canis familiaris	31.78	2.00e-35	140.00
IUUC-Cpo-022196	Cavia porcellus	31.95	3.00e-37	146.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	28.87	6.00e-27	112.00
IUUC-Csa-023551	Chlorocebus sabaeus	32.51	9.00e-37	144.00
IUUC-Cho-024373	Choloepus hoffmanni	32.10	8.00e-32	128.00
IUUC-Cin-025269	Ciona intestinalis	30.17	7.00e-32	128.00
IUUC-Csv-025976	Ciona savignyi	27.00	3.00e-19	86.30
IUUC-Cgl-026386	Colletotrichum gloeosporioides	35.00	5.00e-32	128.00
IUUC-Cne-026950	Cryptococcus neoformans	27.55	1.00e-22	98.20
IUUC-Cme-027199	Cyanidioschyzon merolae	31.33	3.00e-04	37.00
IUUC-Dre-028247	Danio rerio	33.75	5.00e-38	149.00
IUUC-Dno-028974	Dasypus novemcinctus	32.51	9.00e-37	144.00
IUUC-Dor-030143	Dipodomys ordii	32.37	1.00e-35	140.00
IUUC-Dse-031365	Dothistroma septosporum	32.66	4.00e-32	129.00
IUUC-Dme-032197	Drosophila melanogaster	30.20	1.00e-32	131.00
IUUC-Ete-032371	Echinops telfairi	32.51	1.00e-36	144.00
IUUC-Eca-033242	Equus caballus	32.51	1.00e-36	144.00
IUUC-Eeu-035317	Erinaceus europaeus	32.51	9.00e-37	144.00
IUUC-Fca-036061	Felis catus	32.51	1.00e-36	144.00
IUUC-Fal-036715	Ficedula albicollis	33.20	8.00e-37	144.00
IUUC-Fox-037884	Fusarium oxysporum	38.00	1.00e-24	103.00
IUUC-Fso-038150	Fusarium solani	34.69	3.00e-28	117.00
IUUC-Gmo-038750	Gadus morhua	34.85	6.00e-38	148.00
IUUC-Ggr-039959	Gaeumannomyces graminis	28.57	3.00e-21	94.70
IUUC-Gga-040935	Gallus gallus	31.95	1.00e-36	144.00
IUUC-Gac-041478	Gasterosteus aculeatus	34.85	2.00e-38	150.00
IUUC-Gma-043516	Glycine max	31.22	2.00e-32	130.00
IUUC-Ggo-044972	Gorilla gorilla	32.37	2.00e-35	140.00
IUUC-Hsa-046089	Homo sapiens	32.51	9.00e-37	144.00
IUUC-Hvu-047636	Hordeum vulgare	35.00	9.00e-17	77.80
IUUC-Itr-047902	Ictidomys tridecemlineatus	32.78	7.00e-35	138.00
IUUC-Kpa-049127	Komagataella pastoris	35.17	3.00e-40	156.00
IUUC-Lch-050600	Latimeria chalumnae	33.20	2.00e-38	150.00
IUUC-Lpe-051540	Leersia perrieri	33.20	6.00e-38	148.00
IUUC-Loc-051976	Lepisosteus oculatus	36.10	7.00e-39	151.00
IUUC-Lma-053103	Leptosphaeria maculans	30.35	3.00e-29	120.00
IUUC-Laf-053972	Loxodonta africana	33.20	3.00e-37	146.00
IUUC-Mcc-054700	Macaca mulatta	32.37	3.00e-35	139.00
IUUC-Meu-056791	Macropus eugenii	32.35	8.00e-30	121.00
IUUC-Mor-056909	Magnaporthe oryzae	26.88	8.00e-24	101.00
IUUC-Mpo-057299	Magnaporthe poae	29.46	2.00e-26	110.00
IUUC-Mtr-057964	Medicago truncatula	29.96	3.00e-31	126.00
IUUC-Mla-058990	Melampsora laricipopulina	31.42	5.00e-20	89.70
IUUC-Mga-060072	Meleagris gallopavo	32.37	7.00e-36	141.00
IUUC-Mvi-060312	Microbotryum violaceum	30.35	2.00e-32	130.00
IUUC-Mmr-060851	Microcebus murinus	31.54	1.00e-36	144.00
IUUC-Mdo-062241	Monodelphis domestica	34.32	2.00e-36	143.00
IUUC-Mmu-063954	Mus musculus	32.51	3.00e-36	143.00
IUUC-Mac-065016	Musa acuminata	34.09	3.00e-24	102.00
IUUC-Mpu-066870	Mustela putorius furo	31.78	2.00e-35	140.00
IUUC-Mlu-067701	Myotis lucifugus	32.10	1.00e-35	140.00
IUUC-Nfi-068610	Neosartorya fischeri	29.21	9.00e-23	97.80
IUUC-Ncr-068780	Neurospora crassa	26.04	1.00e-21	94.70
IUUC-Nle-069291	Nomascus leucogenys	32.51	9.00e-37	144.00
IUUC-Opr-070682	Ochotona princeps	34.67	9.00e-26	108.00
IUUC-Ont-071910	Oreochromis niloticus	35.27	7.00e-39	151.00
IUUC-Oan-073031	Ornithorhynchus anatinus	32.51	9.00e-37	144.00
IUUC-Ocu-074648	Oryctolagus cuniculus	32.51	1.00e-36	144.00
IUUC-Oba-074993	Oryza barthii	33.61	2.00e-38	149.00
IUUC-Obr-076341	Oryza brachyantha	33.61	7.00e-39	151.00
IUUC-Ogl-077099	Oryza glaberrima	33.61	2.00e-38	149.00
IUUC-Ogu-078285	Oryza glumaepatula	32.78	4.00e-37	145.00
IUUC-Oin-079441	Oryza indica	33.61	1.00e-38	150.00
IUUC-Olo-081037	Oryza longistaminata	33.61	1.00e-38	150.00
IUUC-Ome-081357	Oryza meridionalis	33.61	1.00e-38	150.00
IUUC-Oni-082632	Oryza nivara	33.61	3.00e-38	149.00
IUUC-Opu-083351	Oryza punctata	33.90	1.00e-37	147.00
IUUC-Oru-084306	Oryza rufipogon	33.61	1.00e-38	150.00
IUUC-Osa-085307	Oryza sativa	33.61	1.00e-38	150.00
IUUC-Ola-086371	Oryzias latipes	35.27	1.00e-38	150.00
IUUC-Olu-087646	Ostreococcus lucimarinus	26.47	1.00e-25	108.00
IUUC-Oga-089015	Otolemur garnettii	32.51	2.00e-36	143.00
IUUC-Oar-090405	Ovis aries	32.51	2.00e-36	143.00
IUUC-Ptr-090735	Pan troglodytes	32.51	1.00e-36	144.00
IUUC-Pan-092825	Papio anubis	32.37	2.00e-35	140.00
IUUC-Psi-093110	Pelodiscus sinensis	31.78	5.00e-35	139.00
IUUC-Pma-094196	Petromyzon marinus	36.54	1.00e-27	114.00
IUUC-Pno-095145	Phaeosphaeria nodorum	24.90	4.00e-25	106.00
IUUC-Ppa-095321	Physcomitrella patens	32.20	1.00e-33	134.00
IUUC-Pfo-096813	Poecilia formosa	34.85	4.00e-38	149.00
IUUC-Pab-098197	Pongo abelii	32.63	3.00e-34	136.00
IUUC-Pop-098821	Populus trichocarpa	41.41	9.00e-20	86.70
IUUC-Pca-100218	Procavia capensis	31.95	6.00e-37	145.00
IUUC-Ppe-102032	Prunus persica	32.35	2.00e-34	136.00
IUUC-Pva-102691	Pteropus vampyrus	32.78	9.00e-37	144.00
IUUC-Pgr-103633	Puccinia graminis	27.34	1.00e-21	94.70
IUUC-Ptt-103979	Puccinia triticina	23.70	2.00e-08	51.60
IUUC-Pyt-104428	Pyrenophora triticirepentis	28.22	8.00e-26	108.00
IUUC-Rno-105554	Rattus norvegicus	32.51	1.00e-36	144.00
IUUC-Sce-106358	Saccharomyces cerevisiae	24.31	9.00e-22	95.10
IUUC-Sha-106542	Sarcophilus harrisii	34.44	1.00e-37	147.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	34.57	2.00e-28	116.00
IUUC-Spo-108207	Schizosaccharomyces pombe	34.74	5.00e-29	119.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	31.73	3.00e-34	136.00
IUUC-Smo-108750	Selaginella moellendorffii	29.17	2.00e-30	123.00
IUUC-Sit-110052	Setaria italica	33.76	2.00e-37	146.00
IUUC-Sly-111489	Solanum lycopersicum	31.25	2.00e-32	130.00
IUUC-Stu-112517	Solanum tuberosum	28.39	7.00e-30	121.00
IUUC-Sar-113051	Sorex araneus	34.07	2.00e-21	94.00
IUUC-Sbi-114113	Sorghum bicolor	32.37	2.00e-37	147.00
IUUC-Sre-115221	Sporisorium reilianum	25.00	6.00e-17	79.30
IUUC-Ssc-115547	Sus scrofa	32.51	9.00e-37	144.00
IUUC-Tgu-117196	Taeniopygia guttata	32.78	9.00e-37	144.00
IUUC-Tru-117740	Takifugu rubripes	32.92	1.00e-37	147.00
IUUC-Tsy-119599	Tarsius syrichta	32.51	1.00e-36	144.00
IUUC-Tni-120315	Tetraodon nigroviridis	34.02	1.00e-37	147.00
IUUC-Tca-121033	Theobroma cacao	32.20	3.00e-34	136.00
IUUC-Tre-121986	Trichoderma reesei	32.65	4.00e-30	123.00
IUUC-Tvi-122607	Trichoderma virens	30.92	2.00e-32	130.00
IUUC-Tae-125740	Triticum aestivum	28.72	5.00e-34	135.00
IUUC-Tur-126375	Triticum urartu	26.45	2.00e-30	124.00
IUUC-Tme-126878	Tuber melanosporum	37.08	2.00e-42	164.00
IUUC-Tbe-127429	Tupaia belangeri	34.67	1.00e-25	108.00
IUUC-Ttr-129086	Tursiops truncatus	27.98	6.00e-26	108.00
IUUC-Uma-129364	Ustilago maydis	23.33	3.00e-19	87.00
IUUC-Vda-129929	Verticillium dahliae	32.83	2.00e-27	114.00
IUUC-Vpa-130048	Vicugna pacos	26.34	1.00e-22	97.80
IUUC-Vvi-130834	Vitis vinifera	31.78	9.00e-34	134.00
IUUC-Xtr-131888	Xenopus tropicalis	32.51	6.00e-37	145.00
IUUC-Xma-133580	Xiphophorus maculatus	35.27	8.00e-39	151.00
IUUC-Zma-135642	Zea mays	33.20	1.00e-37	147.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence