iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049134

Ensembl Protein ID

CAY68477

UniProt Accession

C4QZ03; C4QZ03_KOMPG

Genbank Protein ID

CAY68477.1

Protein Name

WD repeat protein required for ubiquitin-mediated protein degradation

Genbank Nucleotide ID

FN392319

Gene Name

PAS_chr1-4_0618

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-4_0618	CAY68477	CAY68477

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-24	82.5	11	40
UBD/Beta-Prp	6.20e-44	148.4	68	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH+ +v+++    s+ ++vs+s+D t++vW+
   Q: 11   GHEQDVRAV-IspSNETIVSASRDQTVRVWN 40
           8*******9.6655599*************9 PP

UBD/Beta-Prp

   S: 60   fspdgk..ilvtgseDrtikvw...dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvs 154
           f++d    ++++g++ ++i +    + +  ++v++l ghe++v+sl++      ++sGs+d t++vw  + g++l+  l+gh+++v+ v++ +     + +
   Q: 68   FQDD-GleLIISGGKNQLIDLTapySTQEEDPVSVLIGHEANVCSLDSKG--PLIISGSWDTTAKVW--QDGSVLY-NLKGHSASVWDVKIIDAVnHEFLT 162
           3444.33699******9999976558889******************988..***************..99****9.*************8665559**** PP
   S: 155  GslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
           +s+D+tv+ W+   +k+++t+tg htd v+ l    ng  ++s+s+d t++++d+   +  ++l+gh+++++s+ ++pn   lvs+++D+s riW     +
   Q: 163  CSADKTVKKWKG--DKVIQTFTG-HTDVVRALLPLANG--FASCSNDATIRIYDYNDPRPTNILTGHESFIYSLGVLPN-GDLVSCGEDRSCRIW--SDHQ 255
           **********66..********9.*******9988865..*************************************55.5688999********..589* PP
   S: 256  llktlqlhnssvisvavlsfgdnvlvlgsedskvniwk 293
           + ++++l+  sv+  +v  + +  +vl+++d+++++++
   Q: 256  CQQVINLPCVSVWDLSV--LPNGDIVLAGSDGNIRVFS 291
           *****************..88889999999******97 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MSFKLSASLK GHEQDVRAVI SPSNETIVSA SRDQTVRVWN KAENSENQWN DGIINHRSTG 60
FINSLAYFQD DGLELIISGG KNQLIDLTAP YSTQEEDPVS VLIGHEANVC SLDSKGPLII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCTTCA AGCTATCTGC ATCTTTAAAG GGCCATGAAC AGGATGTTCG GGCAGTGATA 60
TCTCCTTCAA ATGAGACAAT TGTGTCCGCA TCAAGAGATC AGACTGTTAG AGTGTGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005623--C:cell
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0034517--P:ribophagy
GO:0010992--P:ubiquitin homeostasis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ppa:PAS_chr1-4_0618

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	27.36	1.00e-62	232.00
IUUC-Aml-002125	Ailuropoda melanoleuca	43.07	7.00e-94	336.00
IUUC-Atr-002554	Amborella trichopoda	32.14	5.00e-59	220.00
IUUC-Apl-004094	Anas platyrhynchos	45.95	8.00e-83	299.00
IUUC-Aca-004726	Anolis carolinensis	34.99	2.00e-101	361.00
IUUC-Aly-005961	Arabidopsis lyrata	27.62	9.00e-66	242.00
IUUC-Ath-006639	Arabidopsis thaliana	30.97	1.00e-64	238.00
IUUC-Ago-007772	Ashbya gossypii	37.29	7.00e-137	478.00
IUUC-Acl-008316	Aspergillus clavatus	33.21	3.00e-93	334.00
IUUC-Afl-008532	Aspergillus flavus	34.81	6.00e-92	330.00
IUUC-Afu-008950	Aspergillus fumigatus	33.54	8.00e-97	345.00
IUUC-Ani-009186	Aspergillus nidulans	35.71	4.00e-106	376.00
IUUC-Ang-009575	Aspergillus niger	35.35	4.00e-99	353.00
IUUC-Aor-010086	Aspergillus oryzae	34.81	6.00e-92	330.00
IUUC-Ate-010541	Aspergillus terreus	34.61	8.00e-96	342.00
IUUC-Ame-011633	Astyanax mexicanus	41.00	4.00e-88	317.00
IUUC-Bgr-012292	Blumeria graminis	33.24	2.00e-93	334.00
IUUC-Bta-013218	Bos taurus	43.63	1.00e-93	335.00
IUUC-Bci-013876	Botrytis cinerea	40.80	3.00e-105	374.00
IUUC-Bdi-014810	Brachypodium distachyon	28.61	9.00e-72	262.00
IUUC-Bol-016006	Brassica oleracea	28.31	4.00e-72	263.00
IUUC-Bra-017593	Brassica rapa	28.33	2.00e-71	261.00
IUUC-Cel-018703	Caenorhabditis elegans	27.79	2.00e-43	168.00
IUUC-Cja-019270	Callithrix jacchus	42.27	2.00e-92	331.00
IUUC-Cfa-021262	Canis familiaris	42.73	2.00e-94	338.00
IUUC-Cpo-021449	Cavia porcellus	40.43	7.00e-82	296.00
IUUC-Csa-024140	Chlorocebus sabaeus	43.25	2.00e-94	338.00
IUUC-Cho-024923	Choloepus hoffmanni	38.27	8.00e-37	146.00
IUUC-Cin-025373	Ciona intestinalis	32.28	7.00e-86	309.00
IUUC-Csv-026324	Ciona savignyi	40.08	5.00e-87	313.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	34.07	3.00e-97	347.00
IUUC-Cne-026998	Cryptococcus neoformans	36.88	7.00e-82	296.00
IUUC-Cme-027154	Cyanidioschyzon merolae	31.93	6.00e-49	186.00
IUUC-Dre-028674	Danio rerio	43.63	1.00e-90	325.00
IUUC-Dno-028966	Dasypus novemcinctus	42.98	6.00e-93	333.00
IUUC-Dor-030343	Dipodomys ordii	49.42	3.00e-38	150.00
IUUC-Dse-031385	Dothistroma septosporum	42.00	3.00e-93	333.00
IUUC-Dme-032044	Drosophila melanogaster	30.17	4.00e-78	283.00
IUUC-Ete-032506	Echinops telfairi	46.51	1.00e-33	135.00
IUUC-Eca-033547	Equus caballus	43.41	3.00e-93	334.00
IUUC-Eeu-034462	Erinaceus europaeus	37.86	3.00e-35	141.00
IUUC-Fca-035893	Felis catus	43.51	1.00e-94	338.00
IUUC-Fal-037235	Ficedula albicollis	43.13	3.00e-92	330.00
IUUC-Fox-037836	Fusarium oxysporum	36.42	4.00e-111	393.00
IUUC-Fso-038251	Fusarium solani	36.38	6.00e-107	379.00
IUUC-Gmo-038648	Gadus morhua	41.08	7.00e-91	325.00
IUUC-Ggr-039867	Gaeumannomyces graminis	30.82	2.00e-79	288.00
IUUC-Gga-040989	Gallus gallus	41.48	1.00e-86	312.00
IUUC-Gac-041344	Gasterosteus aculeatus	42.11	5.00e-85	306.00
IUUC-Gma-043067	Glycine max	28.07	2.00e-65	241.00
IUUC-Ggo-045009	Gorilla gorilla	43.13	7.00e-94	335.00
IUUC-Hsa-046807	Homo sapiens	43.35	4.00e-95	340.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	43.63	3.00e-93	334.00
IUUC-Lch-049597	Latimeria chalumnae	41.60	1.00e-84	304.00
IUUC-Lpe-050821	Leersia perrieri	29.47	1.00e-74	272.00
IUUC-Loc-051849	Lepisosteus oculatus	42.86	3.00e-92	331.00
IUUC-Lma-053297	Leptosphaeria maculans	36.60	3.00e-113	400.00
IUUC-Laf-053495	Loxodonta africana	43.20	1.00e-92	332.00
IUUC-Meu-055983	Macropus eugenii	40.47	4.00e-33	134.00
IUUC-Mor-057006	Magnaporthe oryzae	34.92	2.00e-77	281.00
IUUC-Mpo-057465	Magnaporthe poae	36.04	4.00e-78	283.00
IUUC-Mtr-058374	Medicago truncatula	27.21	2.00e-67	248.00
IUUC-Mla-058895	Melampsora laricipopulina	41.34	1.00e-95	341.00
IUUC-Mvi-060297	Microbotryum violaceum	40.00	6.00e-97	346.00
IUUC-Mmr-060810	Microcebus murinus	38.12	7.00e-75	273.00
IUUC-Mdo-062671	Monodelphis domestica	43.10	4.00e-92	330.00
IUUC-Mmu-063536	Mus musculus	35.39	3.00e-97	347.00
IUUC-Mac-064902	Musa acuminata	28.04	2.00e-61	228.00
IUUC-Mpu-066085	Mustela putorius furo	43.29	6.00e-94	336.00
IUUC-Mlu-067907	Myotis lucifugus	42.98	3.00e-93	333.00
IUUC-Nfi-068457	Neosartorya fischeri	33.43	1.00e-77	281.00
IUUC-Ncr-068622	Neurospora crassa	33.58	8.00e-103	365.00
IUUC-Nle-069049	Nomascus leucogenys	42.37	4.00e-91	327.00
IUUC-Opr-071013	Ochotona princeps	48.25	2.00e-25	108.00
IUUC-Ont-071339	Oreochromis niloticus	43.44	5.00e-95	340.00
IUUC-Oan-073353	Ornithorhynchus anatinus	45.95	5.00e-46	175.00
IUUC-Ocu-074625	Oryctolagus cuniculus	43.41	2.00e-93	335.00
IUUC-Oba-075226	Oryza barthii	25.48	9.00e-56	209.00
IUUC-Obr-076875	Oryza brachyantha	29.53	5.00e-76	276.00
IUUC-Ogl-077057	Oryza glaberrima	28.98	4.00e-75	273.00
IUUC-Ogu-078156	Oryza glumaepatula	28.61	4.00e-75	273.00
IUUC-Oin-079373	Oryza indica	28.98	1.00e-74	271.00
IUUC-Olo-080849	Oryza longistaminata	27.12	3.00e-48	184.00
IUUC-Ome-081654	Oryza meridionalis	26.03	4.00e-55	207.00
IUUC-Oni-082221	Oryza nivara	26.27	3.00e-56	211.00
IUUC-Opu-084103	Oryza punctata	26.31	4.00e-54	204.00
IUUC-Oru-084751	Oryza rufipogon	26.03	2.00e-54	205.00
IUUC-Osa-085584	Oryza sativa	28.85	7.00e-74	270.00
IUUC-Ola-086974	Oryzias latipes	42.42	4.00e-92	330.00
IUUC-Oga-088052	Otolemur garnettii	40.35	2.00e-83	301.00
IUUC-Oar-089509	Ovis aries	43.25	1.00e-91	328.00
IUUC-Ptr-090911	Pan troglodytes	43.35	4.00e-95	340.00
IUUC-Pan-092141	Papio anubis	43.04	2.00e-94	337.00
IUUC-Psi-093543	Pelodiscus sinensis	46.23	7.00e-86	309.00
IUUC-Pno-094952	Phaeosphaeria nodorum	37.70	6.00e-108	382.00
IUUC-Ppa-095881	Physcomitrella patens	29.51	1.00e-73	268.00
IUUC-Pfo-096739	Poecilia formosa	40.76	3.00e-87	314.00
IUUC-Pab-098641	Pongo abelii	43.35	8.00e-95	339.00
IUUC-Pop-099493	Populus trichocarpa	29.81	1.00e-72	265.00
IUUC-Pca-100599	Procavia capensis	42.45	3.00e-71	261.00
IUUC-Ppe-101874	Prunus persica	29.17	9.00e-71	259.00
IUUC-Pva-103009	Pteropus vampyrus	47.56	7.00e-82	296.00
IUUC-Pgr-103260	Puccinia graminis	35.18	2.00e-106	377.00
IUUC-Ptt-103711	Puccinia triticina	41.01	2.00e-89	321.00
IUUC-Pte-104337	Pyrenophora teres	36.39	6.00e-103	366.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	36.60	3.00e-103	367.00
IUUC-Rno-105273	Rattus norvegicus	43.84	2.00e-94	338.00
IUUC-Sce-106351	Saccharomyces cerevisiae	39.97	9.00e-138	481.00
IUUC-Sha-106758	Sarcophilus harrisii	43.10	8.00e-91	326.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	35.83	5.00e-105	373.00
IUUC-Spo-108093	Schizosaccharomyces pombe	37.57	5.00e-116	409.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	42.27	3.00e-100	357.00
IUUC-Smo-109368	Selaginella moellendorffii	29.63	4.00e-67	247.00
IUUC-Sit-109699	Setaria italica	29.66	1.00e-78	285.00
IUUC-Sly-111063	Solanum lycopersicum	29.71	5.00e-68	250.00
IUUC-Sar-113199	Sorex araneus	41.90	7.00e-72	263.00
IUUC-Sbi-114745	Sorghum bicolor	29.68	4.00e-76	276.00
IUUC-Sre-115080	Sporisorium reilianum	43.00	9.00e-106	375.00
IUUC-Ssc-115666	Sus scrofa	42.80	2.00e-91	328.00
IUUC-Tgu-116877	Taeniopygia guttata	42.37	1.00e-89	322.00
IUUC-Tru-117580	Takifugu rubripes	42.24	7.00e-92	329.00
IUUC-Tsy-118946	Tarsius syrichta	46.65	2.00e-84	305.00
IUUC-Tni-119755	Tetraodon nigroviridis	41.72	2.00e-90	324.00
IUUC-Tca-120977	Theobroma cacao	32.82	1.00e-63	236.00
IUUC-Tre-122217	Trichoderma reesei	34.59	1.00e-104	372.00
IUUC-Tvi-122671	Trichoderma virens	33.92	2.00e-102	364.00
IUUC-Tae-125581	Triticum aestivum	29.08	2.00e-74	271.00
IUUC-Tme-126971	Tuber melanosporum	36.57	9.00e-118	415.00
IUUC-Tbe-127858	Tupaia belangeri	37.77	8.00e-25	106.00
IUUC-Ttr-128173	Tursiops truncatus	42.83	6.00e-91	326.00
IUUC-Uma-129322	Ustilago maydis	42.47	3.00e-102	363.00
IUUC-Vda-129682	Verticillium dahliae	31.93	3.00e-100	357.00
IUUC-Vpa-130607	Vicugna pacos	46.61	1.00e-87	315.00
IUUC-Vvi-131153	Vitis vinifera	29.32	2.00e-73	268.00
IUUC-Xtr-132208	Xenopus tropicalis	33.85	3.00e-88	317.00
IUUC-Xma-133098	Xiphophorus maculatus	41.77	1.00e-87	315.00
IUUC-Yli-134646	Yarrowia lipolytica	45.61	3.00e-107	380.00
IUUC-Zma-135920	Zea mays	32.52	3.00e-59	221.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence