iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004977

UUCD1 version

UUC-AnC-00306

Ensembl Protein ID

ENSACAP00000023219.1

UniProt Accession

R4GCZ0; R4GCZ0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006681.3	ENSACAT00000030638.1	ENSACAP00000023219.1
ENSACAG00000006681.3	ENSACAT00000006736.3	ENSACAP00000006590.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-18	65.6	190	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d   +l+++s D++++ WD+r+ 
   Q: 190  HLSKIHGLDWhPDneSILATSSQDNSVRFWDYRQP 224
           99*********5556889*************9876 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAARWSSENV VVEFRDAQAT AMSVDCLGQH AVLSGRRFLY IVNLDSPANG HRKISRQSKW 60
DIGAVQWNPH ESHAHYFAAS SNQRVDVYKW KDGNEEVGTS LQGHTRVISD LDWAVFEPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATGCGCCAA GGCTTCCTTC TTTTGCTGCT TCATAAAGTC GTGTCAGACT GCATAATATT 60
AATGGGAATA ATAATAACAC TTAAAGCGAT CTTAAATTGC ATTTATTCTA CAGTGCAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	84.10	0.00e+00	1698.00
IUUC-Apl-004021	Anas platyrhynchos	85.38	0.00e+00	1636.00
IUUC-Ago-007961	Ashbya gossypii	25.57	6.00e-63	236.00
IUUC-Acl-008161	Aspergillus clavatus	28.80	7.00e-57	216.00
IUUC-Afl-008686	Aspergillus flavus	26.67	2.00e-63	238.00
IUUC-Afu-008932	Aspergillus fumigatus	28.60	1.00e-57	218.00
IUUC-Ani-009493	Aspergillus nidulans	28.70	1.00e-60	228.00
IUUC-Ang-009876	Aspergillus niger	29.36	8.00e-60	226.00
IUUC-Aor-009926	Aspergillus oryzae	26.67	2.00e-63	238.00
IUUC-Ate-010274	Aspergillus terreus	34.97	2.00e-52	201.00
IUUC-Ame-011297	Astyanax mexicanus	70.55	0.00e+00	1413.00
IUUC-Bgr-012173	Blumeria graminis	31.88	6.00e-44	173.00
IUUC-Bta-013261	Bos taurus	84.31	0.00e+00	1709.00
IUUC-Bci-013971	Botrytis cinerea	32.52	2.00e-46	181.00
IUUC-Cja-019167	Callithrix jacchus	83.40	0.00e+00	1688.00
IUUC-Cfa-020287	Canis familiaris	83.70	0.00e+00	1685.00
IUUC-Cpo-022510	Cavia porcellus	81.75	0.00e+00	1601.00
IUUC-Csa-023474	Chlorocebus sabaeus	86.52	0.00e+00	1766.00
IUUC-Cho-024634	Choloepus hoffmanni	83.58	0.00e+00	712.00
IUUC-Cin-025642	Ciona intestinalis	31.69	4.00e-136	479.00
IUUC-Csv-025848	Ciona savignyi	45.41	4.00e-55	207.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	33.44	4.00e-45	177.00
IUUC-Cne-027088	Cryptococcus neoformans	26.16	8.00e-44	172.00
IUUC-Dre-028753	Danio rerio	69.90	0.00e+00	1380.00
IUUC-Dno-029733	Dasypus novemcinctus	82.18	0.00e+00	1655.00
IUUC-Dor-030781	Dipodomys ordii	81.36	0.00e+00	847.00
IUUC-Dse-031422	Dothistroma septosporum	23.97	4.00e-16	80.90
IUUC-Dme-031803	Drosophila melanogaster	33.89	7.00e-149	521.00
IUUC-Ete-032622	Echinops telfairi	76.46	0.00e+00	1498.00
IUUC-Eca-033344	Equus caballus	84.51	0.00e+00	1699.00
IUUC-Eeu-034523	Erinaceus europaeus	75.51	0.00e+00	1459.00
IUUC-Fca-035650	Felis catus	84.51	0.00e+00	1709.00
IUUC-Fal-037404	Ficedula albicollis	85.55	0.00e+00	1684.00
IUUC-Fox-037955	Fusarium oxysporum	33.09	1.00e-42	169.00
IUUC-Fso-038289	Fusarium solani	32.92	1.00e-46	182.00
IUUC-Gmo-038547	Gadus morhua	68.58	0.00e+00	1418.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.86	2.00e-43	172.00
IUUC-Gga-041030	Gallus gallus	85.70	0.00e+00	1693.00
IUUC-Gac-042581	Gasterosteus aculeatus	71.69	0.00e+00	1451.00
IUUC-Ggo-044641	Gorilla gorilla	84.51	0.00e+00	1711.00
IUUC-Hsa-046134	Homo sapiens	84.41	0.00e+00	1709.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	86.99	0.00e+00	677.00
IUUC-Kpa-049091	Komagataella pastoris	33.44	8.00e-47	182.00
IUUC-Lch-050288	Latimeria chalumnae	73.67	0.00e+00	1467.00
IUUC-Loc-052802	Lepisosteus oculatus	75.63	0.00e+00	1528.00
IUUC-Lma-053296	Leptosphaeria maculans	32.29	5.00e-48	187.00
IUUC-Laf-053997	Loxodonta africana	86.42	0.00e+00	1777.00
IUUC-Mcc-055855	Macaca mulatta	84.41	0.00e+00	1695.00
IUUC-Meu-056898	Macropus eugenii	80.72	0.00e+00	642.00
IUUC-Mor-056913	Magnaporthe oryzae	36.04	2.00e-43	171.00
IUUC-Mpo-057612	Magnaporthe poae	37.96	1.00e-44	175.00
IUUC-Mla-059097	Melampsora laricipopulina	30.06	1.00e-45	179.00
IUUC-Mga-059218	Meleagris gallopavo	85.25	0.00e+00	1655.00
IUUC-Mvi-060251	Microbotryum violaceum	31.29	3.00e-46	180.00
IUUC-Mmr-061093	Microcebus murinus	82.07	0.00e+00	1642.00
IUUC-Mdo-062757	Monodelphis domestica	83.03	0.00e+00	1649.00
IUUC-Mmu-063839	Mus musculus	85.31	0.00e+00	1755.00
IUUC-Mpu-065977	Mustela putorius furo	84.21	0.00e+00	1699.00
IUUC-Mlu-067460	Myotis lucifugus	82.54	0.00e+00	1691.00
IUUC-Nfi-068250	Neosartorya fischeri	28.60	2.00e-57	218.00
IUUC-Ncr-068710	Neurospora crassa	33.64	1.00e-46	182.00
IUUC-Nle-070011	Nomascus leucogenys	84.21	0.00e+00	1703.00
IUUC-Opr-070731	Ochotona princeps	84.51	0.00e+00	1010.00
IUUC-Ont-072165	Oreochromis niloticus	69.03	0.00e+00	1399.00
IUUC-Oan-072887	Ornithorhynchus anatinus	86.41	0.00e+00	1759.00
IUUC-Ocu-073926	Oryctolagus cuniculus	85.95	0.00e+00	1605.00
IUUC-Ola-087111	Oryzias latipes	68.27	0.00e+00	1387.00
IUUC-Oga-088850	Otolemur garnettii	84.51	0.00e+00	1705.00
IUUC-Oar-090291	Ovis aries	84.00	0.00e+00	1702.00
IUUC-Ptr-091044	Pan troglodytes	84.10	0.00e+00	1699.00
IUUC-Pan-092374	Papio anubis	86.42	0.00e+00	1764.00
IUUC-Psi-093170	Pelodiscus sinensis	55.69	0.00e+00	969.00
IUUC-Pma-094544	Petromyzon marinus	67.86	1.00e-171	595.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.86	2.00e-44	174.00
IUUC-Pfo-096480	Poecilia formosa	68.67	0.00e+00	1357.00
IUUC-Pab-098134	Pongo abelii	83.03	0.00e+00	1665.00
IUUC-Pca-100763	Procavia capensis	65.96	0.00e+00	897.00
IUUC-Pva-102544	Pteropus vampyrus	83.50	0.00e+00	1699.00
IUUC-Pgr-103257	Puccinia graminis	31.60	5.00e-49	190.00
IUUC-Ptt-103942	Puccinia triticina	31.19	7.00e-45	176.00
IUUC-Pte-104065	Pyrenophora teres	32.51	1.00e-46	182.00
IUUC-Rno-105468	Rattus norvegicus	83.71	0.00e+00	1594.00
IUUC-Sce-106356	Saccharomyces cerevisiae	28.12	1.00e-59	225.00
IUUC-Sha-106662	Sarcophilus harrisii	84.76	0.00e+00	1685.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	26.19	6.00e-82	299.00
IUUC-Spo-108265	Schizosaccharomyces pombe	26.05	3.00e-74	273.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	33.14	8.00e-46	179.00
IUUC-Sar-113525	Sorex araneus	79.93	0.00e+00	935.00
IUUC-Sre-115163	Sporisorium reilianum	37.05	9.00e-40	159.00
IUUC-Ssc-115381	Sus scrofa	81.82	0.00e+00	904.00
IUUC-Tgu-116525	Taeniopygia guttata	82.09	0.00e+00	1612.00
IUUC-Tru-118432	Takifugu rubripes	70.26	0.00e+00	1445.00
IUUC-Tsy-119306	Tarsius syrichta	74.56	0.00e+00	857.00
IUUC-Tni-120757	Tetraodon nigroviridis	69.46	0.00e+00	1399.00
IUUC-Tre-122187	Trichoderma reesei	35.69	1.00e-47	186.00
IUUC-Tvi-122367	Trichoderma virens	35.52	9.00e-48	186.00
IUUC-Tme-126986	Tuber melanosporum	28.94	7.00e-64	239.00
IUUC-Tbe-127800	Tupaia belangeri	71.51	0.00e+00	1217.00
IUUC-Ttr-129154	Tursiops truncatus	82.25	0.00e+00	938.00
IUUC-Uma-129366	Ustilago maydis	35.57	1.00e-38	155.00
IUUC-Vda-129827	Verticillium dahliae	34.49	5.00e-48	186.00
IUUC-Vpa-130493	Vicugna pacos	84.22	0.00e+00	1659.00
IUUC-Xtr-131941	Xenopus tropicalis	78.48	0.00e+00	1566.00
IUUC-Xma-133903	Xiphophorus maculatus	67.95	0.00e+00	1380.00
IUUC-Yli-134549	Yarrowia lipolytica	36.36	8.00e-56	212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence