iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022496

Ensembl Protein ID

ENSCPOP00000010949.2

UniProt Accession

H0VKU6; H0VKU6_CAVPO

Genbank Protein ID

ENSCPOP00000010949

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02023771

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000012176.3	ENSCPOT00000012292.2	ENSCPOP00000010949.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-29	100.0	567	599
UBD/Beta-Prp	2.90e-45	154.7	563	777

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt+++W+++
   Q: 567  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNTT 599
           8**********9853.89**************75 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls...lsfspsg.dklvsGshdrtirvwdletgqcle 130
             l gh+++v+ + +s   + l+++s D+t+++w+     +  t+ + ++++     +++  s+ +++v+  +  +  ++++et+q + 
   Q: 563  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALTVFNDNQELGIpasVDLVSSDpSHMVASFSKGYTSIFNMETQQRIL 651
           5689******************************99999888888877777665444444444438888888899************** PP
   S: 131  e......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtge 213
           +        s  +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++++
   Q: 652  TlesnldSMSSSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKT 739
           9999876556666678888899*99**************************98.*********************************** PP
   S: 214  cvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 740  CIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 777
           *********999999******************97655 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA AAAGDGAATA GAARAQYSLP GILHFLQHEW 60
ARFEVERAQW EVERAELQAQ IAFLQGERKG QENLKKDLVR RIKMLEYALK QERAKYHKLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGC AGGCGGGTCC CGGCGTCTTC TTCAGCAACA ACCACCCGGG CGCCGGCGGT 60
GCTAAGGGAC TCGGGCCTCT GGCTGAGGCT GCCGCGGCCG GCGACGGGGC AGCTACGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	96.73	0.00e+00	1344.00
IUUC-Apl-003927	Anas platyrhynchos	87.80	0.00e+00	1115.00
IUUC-Aca-004933	Anolis carolinensis	80.63	0.00e+00	1149.00
IUUC-Ame-010997	Astyanax mexicanus	73.53	0.00e+00	1072.00
IUUC-Bta-013077	Bos taurus	96.41	0.00e+00	1365.00
IUUC-Cja-018973	Callithrix jacchus	97.18	0.00e+00	1373.00
IUUC-Cfa-020988	Canis familiaris	93.60	0.00e+00	1217.00
IUUC-Csa-023829	Chlorocebus sabaeus	96.42	0.00e+00	1363.00
IUUC-Dre-028560	Danio rerio	69.05	0.00e+00	973.00
IUUC-Dno-029742	Dasypus novemcinctus	90.64	0.00e+00	1302.00
IUUC-Dor-030721	Dipodomys ordii	89.10	0.00e+00	1246.00
IUUC-Eca-033760	Equus caballus	96.59	0.00e+00	1269.00
IUUC-Eeu-034953	Erinaceus europaeus	96.09	0.00e+00	742.00
IUUC-Fca-036530	Felis catus	96.16	0.00e+00	1273.00
IUUC-Fal-037353	Ficedula albicollis	81.16	0.00e+00	885.00
IUUC-Gga-040132	Gallus gallus	87.76	0.00e+00	1132.00
IUUC-Gac-041713	Gasterosteus aculeatus	72.96	0.00e+00	1050.00
IUUC-Ggo-045455	Gorilla gorilla	85.08	0.00e+00	1165.00
IUUC-Hsa-046415	Homo sapiens	97.18	0.00e+00	1369.00
IUUC-Lch-050475	Latimeria chalumnae	81.01	0.00e+00	1177.00
IUUC-Loc-051859	Lepisosteus oculatus	76.46	0.00e+00	1126.00
IUUC-Laf-053537	Loxodonta africana	96.28	0.00e+00	1379.00
IUUC-Mcc-055817	Macaca mulatta	96.17	0.00e+00	1363.00
IUUC-Meu-055946	Macropus eugenii	69.91	0.00e+00	904.00
IUUC-Mga-059694	Meleagris gallopavo	88.07	0.00e+00	1113.00
IUUC-Mmr-060768	Microcebus murinus	97.69	0.00e+00	1401.00
IUUC-Mdo-061901	Monodelphis domestica	86.55	0.00e+00	1306.00
IUUC-Mmu-064154	Mus musculus	96.15	0.00e+00	1358.00
IUUC-Mpu-065827	Mustela putorius furo	91.84	0.00e+00	1357.00
IUUC-Mlu-067102	Myotis lucifugus	96.33	0.00e+00	1337.00
IUUC-Ncr-068831	Neurospora crassa	39.60	6.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	96.73	0.00e+00	1273.00
IUUC-Opr-071067	Ochotona princeps	61.00	4.00e-176	611.00
IUUC-Ont-072025	Oreochromis niloticus	73.16	0.00e+00	1044.00
IUUC-Oan-072950	Ornithorhynchus anatinus	90.72	0.00e+00	1159.00
IUUC-Ocu-074316	Oryctolagus cuniculus	95.73	0.00e+00	1253.00
IUUC-Ola-087279	Oryzias latipes	71.07	0.00e+00	1027.00
IUUC-Oga-088284	Otolemur garnettii	97.05	0.00e+00	1374.00
IUUC-Oar-090304	Ovis aries	96.92	0.00e+00	1371.00
IUUC-Ptr-091052	Pan troglodytes	97.31	0.00e+00	1369.00
IUUC-Pan-092270	Papio anubis	91.18	0.00e+00	1322.00
IUUC-Psi-093907	Pelodiscus sinensis	87.59	0.00e+00	1043.00
IUUC-Pfo-097042	Poecilia formosa	72.31	0.00e+00	1127.00
IUUC-Pab-098110	Pongo abelii	97.31	0.00e+00	1369.00
IUUC-Pca-100266	Procavia capensis	84.79	0.00e+00	983.00
IUUC-Pva-102824	Pteropus vampyrus	94.49	0.00e+00	1344.00
IUUC-Pgr-103483	Puccinia graminis	36.71	1.00e-55	212.00
IUUC-Rno-105638	Rattus norvegicus	96.54	0.00e+00	1367.00
IUUC-Sha-107004	Sarcophilus harrisii	88.12	0.00e+00	1120.00
IUUC-Sre-115115	Sporisorium reilianum	33.85	2.00e-63	237.00
IUUC-Ssc-115280	Sus scrofa	97.56	0.00e+00	1382.00
IUUC-Tgu-116759	Taeniopygia guttata	88.49	0.00e+00	1135.00
IUUC-Tru-117944	Takifugu rubripes	73.29	0.00e+00	1049.00
IUUC-Tsy-119405	Tarsius syrichta	85.04	0.00e+00	1062.00
IUUC-Tni-120571	Tetraodon nigroviridis	72.73	0.00e+00	1055.00
IUUC-Uma-129659	Ustilago maydis	34.70	8.00e-64	238.00
IUUC-Vpa-130294	Vicugna pacos	96.72	0.00e+00	1260.00
IUUC-Xma-134233	Xiphophorus maculatus	68.10	0.00e+00	907.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence