iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059346

UUCD1 version

UUC-MeG-00857

Ensembl Protein ID

ENSMGAP00000012292.1

UniProt Accession

G1NGQ7; G1NGQ7_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000011724.1	ENSMGAT00000013181.1	ENSMGAP00000012292.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-85	287.5	44	754

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg...........ellkslqklfeel.......w.... 61
           +Gl+NlgNtCY+NSvLQ+L+++p ++  +++      kkke+l++e + + ++           el++sl++l+ ++       +    
   Q: 44   VGLNNLGNTCYLNSVLQVLYFCPGFKTGIKHlyniisKKKESLKDEGELKAEKgnckedplasyELICSLHSLILSVeqlqasfLlnpe 132
           6******************************7777776666666665544444788888888998888888888877554444425555 PP
   S: 62   .kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk................eknkpkeeeeeedkselsde.... 129
            ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                 +      e           e    
   Q: 133  kYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeelnklpleepkaK-----VE-----------Ekinq 205
           588888*****************************************5555565555544222220.....12...........12223 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 206  ssesngtghsaeeeentpsshvgeiaedklpkgngkrksdaeggnakkkskvskeqiaaeenqrqtrskrkatgeklenqtdaiakcsa 294
           3445567888889999************************************************************************* PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 295  enesakptqkksrlklnwlkssckqpsilskfyslgklttnlgskdpvkeyddceleestakcengndikedgheptspveshnekgte 383
           *********************************************************************************99988764 PP
   S: 130  ...aeekkkkknk.....slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftk 196
              ++e      +     +l+++lFqgql  +++clec+  ++r+e+f+d+s+pv+++e +k+e              +l++++++f++
   Q: 384  kepKKEG-----TelavfELVEKLFQGQLVLRTRCLECECFTERREDFQDISVPVQEDELSKTEesseispepktemkTLKWAISQFAS 467
           4333333.....246666*****************************************998889************************ PP
   S: 197  eeelegenkyycekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeL 280
            e++ ge+ky+ce+c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L
   Q: 468  VERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGL-SKINTPLLTPLKLSLEEWSTKPT-----NDTYGL 550
           **************************************************9555.6********************98.....789*** PP
   S: 281  iavvvHsG.slssGHYvayvkn................................................................... 301
           +avv+HsG ++ssGHY+a vk                                                                    
   Q: 551  FAVVMHSGiTISSGHYTASVKItdlnsleldkgnfitaqmcetikpeplneeeartvaedydngevsfrvngnaqpgkvlnkknmeavg 639
           ***************************************************************************************** PP
   S: 302  .........................................................................ekgkWllfdDskVtev 317
                                                                                     +gkWllfdDs+V+++
   Q: 640  llggqksksdcdlytnrpansekvlnvvtenrnpesgpangsvecstehgdqngvafsglenkalyvlqslkeYEGKWLLFDDSEVKVT 728
           **************************************999999999999999999999998888888877766999************ PP
   S: 318  keeevleetg......staYvlfYkr 337
           +e+++l++ +      st+Y+lfYk+
   Q: 729  EEKDFLNSLSptsastSTPYLLFYKK 754
           *******888**************97 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

XTEPPENEQK CAELRGAEID QVVPAAQPPS LVSCEKKDNM LPFVGLNNLG NTCYLNSVLQ 60
VLYFCPGFKT GIKHLYNIIS KKKESLKDEG ELKAEKGNCK EDPLASYELI CSLHSLILSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNCACCGAGC CGCCGGAGAA TGAGCAGAAG TGCGCGGAGC TCCGCGGCGC AGAGATGTAC 60
GTAGGGGTGC GGGTGCTGCC CGTTGGGATC CCGCTCTGTG CCTGCTGCCG TTTCCCTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	73.55	0.00e+00	1030.00
IUUC-Apl-004204	Anas platyrhynchos	93.08	0.00e+00	1249.00
IUUC-Aca-004637	Anolis carolinensis	72.75	0.00e+00	998.00
IUUC-Ame-011718	Astyanax mexicanus	50.00	9.00e-171	593.00
IUUC-Bta-012552	Bos taurus	71.04	0.00e+00	1014.00
IUUC-Cja-019588	Callithrix jacchus	73.03	0.00e+00	1033.00
IUUC-Cfa-020211	Canis familiaris	74.04	0.00e+00	1052.00
IUUC-Cpo-021551	Cavia porcellus	68.03	0.00e+00	951.00
IUUC-Csa-024186	Chlorocebus sabaeus	73.78	0.00e+00	1038.00
IUUC-Cho-024739	Choloepus hoffmanni	60.59	9.00e-138	483.00
IUUC-Dre-028184	Danio rerio	49.02	1.00e-177	615.00
IUUC-Dno-029669	Dasypus novemcinctus	72.01	0.00e+00	1030.00
IUUC-Dor-030168	Dipodomys ordii	68.16	0.00e+00	903.00
IUUC-Dme-031732	Drosophila melanogaster	29.38	3.00e-18	87.00
IUUC-Ete-032825	Echinops telfairi	68.96	0.00e+00	728.00
IUUC-Eca-033595	Equus caballus	72.87	0.00e+00	1002.00
IUUC-Eeu-034877	Erinaceus europaeus	71.03	1.00e-120	427.00
IUUC-Fca-035381	Felis catus	71.98	0.00e+00	698.00
IUUC-Fal-037592	Ficedula albicollis	85.30	0.00e+00	1167.00
IUUC-Gmo-039680	Gadus morhua	45.83	7.00e-163	566.00
IUUC-Gga-041196	Gallus gallus	95.25	0.00e+00	1338.00
IUUC-Gac-042292	Gasterosteus aculeatus	47.62	3.00e-134	472.00
IUUC-Ggo-044671	Gorilla gorilla	73.12	0.00e+00	1029.00
IUUC-Hsa-047020	Homo sapiens	73.12	0.00e+00	1032.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	65.79	0.00e+00	888.00
IUUC-Lch-050543	Latimeria chalumnae	59.19	0.00e+00	737.00
IUUC-Loc-052338	Lepisosteus oculatus	54.79	0.00e+00	709.00
IUUC-Laf-053707	Loxodonta africana	72.42	0.00e+00	1028.00
IUUC-Mcc-055885	Macaca mulatta	73.52	0.00e+00	1038.00
IUUC-Meu-056573	Macropus eugenii	67.81	0.00e+00	865.00
IUUC-Mmr-061612	Microcebus murinus	72.69	0.00e+00	1014.00
IUUC-Mdo-062887	Monodelphis domestica	70.84	0.00e+00	949.00
IUUC-Mmu-064044	Mus musculus	72.14	0.00e+00	1012.00
IUUC-Mpu-066847	Mustela putorius furo	74.04	0.00e+00	1048.00
IUUC-Mlu-067684	Myotis lucifugus	73.85	0.00e+00	1034.00
IUUC-Nle-070057	Nomascus leucogenys	73.39	0.00e+00	1036.00
IUUC-Opr-070463	Ochotona princeps	66.40	0.00e+00	882.00
IUUC-Ont-071975	Oreochromis niloticus	46.03	1.00e-158	553.00
IUUC-Oan-073062	Ornithorhynchus anatinus	75.00	7.00e-22	95.90
IUUC-Ocu-074840	Oryctolagus cuniculus	71.94	0.00e+00	1025.00
IUUC-Ola-087088	Oryzias latipes	47.88	8.00e-167	580.00
IUUC-Oga-088472	Otolemur garnettii	72.70	0.00e+00	1018.00
IUUC-Oar-089498	Ovis aries	72.16	0.00e+00	1023.00
IUUC-Ptr-091395	Pan troglodytes	73.12	0.00e+00	1033.00
IUUC-Pan-092462	Papio anubis	73.65	0.00e+00	1038.00
IUUC-Psi-093583	Pelodiscus sinensis	82.32	0.00e+00	1066.00
IUUC-Pma-094644	Petromyzon marinus	46.00	2.00e-25	108.00
IUUC-Pfo-096314	Poecilia formosa	47.04	9.00e-157	546.00
IUUC-Pab-098568	Pongo abelii	73.25	0.00e+00	1033.00
IUUC-Pca-100948	Procavia capensis	67.03	3.00e-133	469.00
IUUC-Pva-102853	Pteropus vampyrus	72.36	0.00e+00	1022.00
IUUC-Rno-105573	Rattus norvegicus	72.18	0.00e+00	1023.00
IUUC-Sha-107495	Sarcophilus harrisii	68.57	0.00e+00	844.00
IUUC-Sar-113545	Sorex araneus	61.07	0.00e+00	788.00
IUUC-Ssc-115962	Sus scrofa	73.03	0.00e+00	1026.00
IUUC-Tgu-116731	Taeniopygia guttata	85.01	0.00e+00	1169.00
IUUC-Tru-117893	Takifugu rubripes	45.92	1.00e-146	513.00
IUUC-Tsy-119644	Tarsius syrichta	79.49	4.00e-135	474.00
IUUC-Tni-119819	Tetraodon nigroviridis	44.59	5.00e-161	560.00
IUUC-Tbe-127272	Tupaia belangeri	69.26	0.00e+00	924.00
IUUC-Ttr-128404	Tursiops truncatus	73.12	0.00e+00	1020.00
IUUC-Vpa-130205	Vicugna pacos	72.05	0.00e+00	1022.00
IUUC-Xtr-132613	Xenopus tropicalis	56.05	0.00e+00	740.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence