iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119819

UUCD1 version

UUC-TeN-01162

Ensembl Protein ID

ENSTNIP00000021262.1

UniProt Accession

H3DL64; H3DL64_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000018097.1	ENSTNIT00000021497.1	ENSTNIP00000021262.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.20e-85	285.5	73	735

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..............kkkeklneenpkepkg...............ellkslqklfeel 60
           +Gl+NlgNtCY+NSvLQ+L+ +p lr+ +++              +              +               ell s+++l++++
   Q: 73   VGLNNLGNTCYLNSVLQVLYYCPGLRDGMKKlhklskrrakpkkeE--------------TneqsaevpedsppqvELLASFNSLIASI 147
           6******************************666554444332220..............12233344444444459999999999999 PP
   S: 61   wkskkk............avsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk..............eknkpkeeeeeedk 123
            + +++            a+ pr++l++l++++++++gy q+DaqE+l+++l  ++e+++                     +e      
   Q: 148  EQLQSGflrnpdsfgdelATPPRKILHTLRQLNPMYEGYLQHDAQEVLQCILGYIQEACDTirreqglnsddtaqV-----KE------ 225
           533333555555666677*****************************************66444555544332220.....22...... PP
   S: 124  selsde................................................................................... 129
                e                                                                                   
   Q: 226  -----Esggsaaeaqssqedesqggskrksdtevgnakkkpksvgpkksdteretrskpvtrskrrssgdavasktadpvdgkrkkkak 309
           .....2334444455557778888899999999******************************************************** PP
   S: 130  ...........................................................aeekkkkknk................slis 143
                                                                               +                +l++
   Q: 310  lswlrpsgkqpsifskfrrvgkisstvklpnkpgqgtepgegqrsseksseeerpqnmdT--------PkkrircptfpleldglDLME 390
           *******************************************99999887776653331........03344467788888888**** PP
   S: 144  dlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeae 218
           +lFqgql  +++clec++ ++r+e+f+d+s+pv +++ +++               +l++++ +f++ e++ ge+ky+ce+c++++eae
   Q: 391  NLFQGQLVLRTRCLECESFTERREDFQDISVPVLEDSPSSPHdlcsvspdpkpelkTLTWAIGQFASVERIVGEDKYFCETCHHYTEAE 479
           *************************************88777*********************************************** PP
   S: 219  kklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn 301
           ++l ++k Pev+++hLkRf     + + +    +k+n+ +++pl+L+l+++ct+p+ +q  +++Y+L+av++HsG ++ssGHY+ayv+ 
   Q: 480  RSLLFDKTPEVITIHLKRFsanslELDPY-AGLSKVNTPLQTPLTLSLEEWCTRPSAAQ--EQRYQLFAVIMHSGvTISSGHYTAYVRM 565
           *******************5555555555.4567**********************998..9*************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 566  sdlrdvrprlrdsqeseaampkkdqplsyddgevsfnltgrrglslpggktgskklseggvgllggqrrlssyelgngspqtekaagae 654
           ***************************************************************************************** PP
   S: 302  ......................................ekgkWllfdDskVtevkeeevleetg......staYvlfYkrr 338
                                                  +gkWllfdD +V+ ++ee++l+ ++      st+Y+lfY+r+
   Q: 655  gskrrktinslsqhpeagvkkepgagtrssraldhllqYEGKWLLFDDCEVRLCEEEDFLRACSpetcssSTPYLLFYRRM 735
           ***999999999999999999999988888888888777999*******************999***************96 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

GAPMRRNKLS LKFLQKKETK RALDFSETQA DEPKNGLFKF SSCDQVVPGP SPCPASPGFL 60
LPSDKKENLV PFVGLNNLGN TCYLNSVLQV LYYCPGLRDG MKKLHKLSKR RAKPKKEETN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCCCCCA TGAGGAGGAA TAAACTCTCT CTCAAGTTTC TCCAGAAGAA GGAAACAAAA 60
CGGGCTCTAG ATTTCTCTGA AACACAAGCG GATGAACCAA AAAATGGTTG AACCACTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	46.20	6.00e-179	620.00
IUUC-Apl-004204	Anas platyrhynchos	45.93	3.00e-157	548.00
IUUC-Aca-004637	Anolis carolinensis	46.56	2.00e-172	598.00
IUUC-Ame-011718	Astyanax mexicanus	53.18	0.00e+00	683.00
IUUC-Bta-012552	Bos taurus	47.22	0.00e+00	628.00
IUUC-Cja-019588	Callithrix jacchus	47.47	2.00e-179	622.00
IUUC-Cfa-020211	Canis familiaris	46.75	2.00e-179	622.00
IUUC-Cpo-021551	Cavia porcellus	48.12	4.00e-177	614.00
IUUC-Csa-024186	Chlorocebus sabaeus	47.85	1.00e-179	623.00
IUUC-Cho-024739	Choloepus hoffmanni	39.06	3.00e-79	289.00
IUUC-Dre-028184	Danio rerio	53.94	0.00e+00	692.00
IUUC-Dno-029669	Dasypus novemcinctus	45.96	6.00e-175	607.00
IUUC-Dor-030168	Dipodomys ordii	44.88	6.00e-158	551.00
IUUC-Dme-031732	Drosophila melanogaster	32.68	7.00e-23	102.00
IUUC-Ete-032825	Echinops telfairi	44.63	1.00e-106	380.00
IUUC-Eca-033595	Equus caballus	46.66	8.00e-165	573.00
IUUC-Eeu-034877	Erinaceus europaeus	45.74	4.00e-71	262.00
IUUC-Fca-035381	Felis catus	48.62	3.00e-137	481.00
IUUC-Fal-037592	Ficedula albicollis	48.00	3.00e-171	595.00
IUUC-Gmo-039680	Gadus morhua	57.12	0.00e+00	728.00
IUUC-Gga-041196	Gallus gallus	45.71	2.00e-171	595.00
IUUC-Gac-042292	Gasterosteus aculeatus	60.26	0.00e+00	740.00
IUUC-Ggo-044671	Gorilla gorilla	47.66	5.00e-179	620.00
IUUC-Hsa-047020	Homo sapiens	47.41	2.00e-178	619.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	43.43	4.00e-151	528.00
IUUC-Lch-050543	Latimeria chalumnae	47.76	1.00e-155	543.00
IUUC-Loc-052338	Lepisosteus oculatus	52.32	0.00e+00	699.00
IUUC-Laf-053707	Loxodonta africana	46.15	2.00e-176	612.00
IUUC-Mcc-055885	Macaca mulatta	47.73	8.00e-180	623.00
IUUC-Meu-056573	Macropus eugenii	46.51	2.00e-141	496.00
IUUC-Mga-059346	Meleagris gallopavo	46.19	3.00e-165	575.00
IUUC-Mmr-061612	Microcebus murinus	45.85	2.00e-175	608.00
IUUC-Mdo-062887	Monodelphis domestica	46.62	2.00e-165	575.00
IUUC-Mmu-064044	Mus musculus	47.41	1.00e-177	616.00
IUUC-Mpu-066847	Mustela putorius furo	46.75	0.00e+00	630.00
IUUC-Mlu-067684	Myotis lucifugus	47.11	3.00e-175	608.00
IUUC-Nle-070057	Nomascus leucogenys	47.73	3.00e-179	621.00
IUUC-Opr-070463	Ochotona princeps	42.75	2.00e-147	516.00
IUUC-Ont-071975	Oreochromis niloticus	60.88	0.00e+00	778.00
IUUC-Oan-073062	Ornithorhynchus anatinus	60.00	1.00e-26	112.00
IUUC-Ocu-074840	Oryctolagus cuniculus	45.84	4.00e-176	611.00
IUUC-Ola-087088	Oryzias latipes	59.30	0.00e+00	810.00
IUUC-Oga-088472	Otolemur garnettii	46.36	4.00e-173	601.00
IUUC-Oar-089498	Ovis aries	47.53	0.00e+00	632.00
IUUC-Ptr-091395	Pan troglodytes	47.66	9.00e-179	620.00
IUUC-Pan-092462	Papio anubis	47.73	6.00e-180	624.00
IUUC-Psi-093583	Pelodiscus sinensis	46.36	4.00e-145	508.00
IUUC-Pma-094644	Petromyzon marinus	37.02	2.00e-29	121.00
IUUC-Pfo-096314	Poecilia formosa	60.25	0.00e+00	814.00
IUUC-Pab-098568	Pongo abelii	47.60	6.00e-179	620.00
IUUC-Pca-100948	Procavia capensis	45.30	8.00e-81	294.00
IUUC-Pva-102853	Pteropus vampyrus	46.37	7.00e-178	617.00
IUUC-Rno-105573	Rattus norvegicus	47.40	3.00e-177	615.00
IUUC-Sha-107495	Sarcophilus harrisii	47.95	1.00e-139	489.00
IUUC-Sar-113545	Sorex araneus	41.54	1.00e-130	460.00
IUUC-Ssc-115962	Sus scrofa	46.48	0.00e+00	632.00
IUUC-Tgu-116731	Taeniopygia guttata	48.17	5.00e-171	594.00
IUUC-Tru-117893	Takifugu rubripes	76.24	0.00e+00	985.00
IUUC-Tsy-119644	Tarsius syrichta	44.86	1.00e-80	294.00
IUUC-Tbe-127272	Tupaia belangeri	44.50	4.00e-148	518.00
IUUC-Ttr-128404	Tursiops truncatus	46.97	5.00e-179	620.00
IUUC-Vpa-130205	Vicugna pacos	46.68	3.00e-178	618.00
IUUC-Xtr-132613	Xenopus tropicalis	46.63	8.00e-174	603.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence