iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033909

UUCD1 version

UUC-EqC-00176

Ensembl Protein ID

ENSECAP00000010518.1

UniProt Accession

F6SGN1; F6SGN1_HORSE

Protein Name

Uncharacterized protein

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000012293.1	ENSECAT00000013267.1	ENSECAP00000010518.1
ENSECAG00000012293.1	ENSECAT00000013271.1	ENSECAP00000010522.1
ENSECAG00000012293.1	ENSECAT00000013284.1	ENSECAP00000010533.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-55	182.8	1559	1591
UBD/Beta-Prp	1.20e-112	376.1	585	799

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htd.svtclaf.sd.tllvsGsdDgtikvWDlr 31
           H d ++++la  ++ ++++s++ Dgt+++WD+ 
   Q: 1559 HVDgPIWGLAThPSrDFFLSAAEDGTVRLWDIA 1591
           555369999989888****************75 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           h ++ i c++ +p k+++atg  +rd +i +wd++t k l+ l   h+ +v av+fs dgk l++++ D  +ti +wd ++g+ +++ +
   Q: 585  H-DDDILCLALHPLKDYVATGqvGRDPSIHIWDTETIKPLSILkGYHQYGVCAVDFSADGKRLASVGIDdgHTIVLWDWKKGEKLSIAR 672
           4.555556999*********95569******************5559******************999999****************** PP
   S: 92   ghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           g +d++  ++++p+  dkl++++  +  + w+   g  +         g++++ +c+v+  ++ + +sG+  + v +W  +  +l++t 
   Q: 673  GSKDKIFVVKMNPYVpDKLITAG-IKHMKFWHRAGGGLIGRkgyiGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDVFLVKTV 758
           *************9978888887.9999***88777777769998445677799************************..889****** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           +  h+++v s+   +  k +v+g++dg v lwd + ++c++t+ 
   Q: 759  KA-HDGPVFSMHALE--KGFVTGGKDGVVALWDDSFERCLKTYA 799
           98.********9888..67**********************996 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MLSMAPGHTD RIFDISWDLY QPNKLVSCGV KHIKFWSLCG NALTPKRGVF GKTGDLQTIL 60
CLACARDELT YSGALNGDIY VWKGINLIRT IQGAHTAGIF SMNACEEGFA TGGRDGCIRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACCAGTGC TCGCATCAAC CTCTACTACA CGGGTGCCAA AGGAGATCGT GTACTTCGTG 60
GCGGGTCGTC GGCGTGGTGT ACAGCCTGCG GGAGCTCCGG CAGAAGTTCT ACCGGGGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	97.00	0.00e+00	3610.00
IUUC-Apl-003360	Anas platyrhynchos	91.08	0.00e+00	3410.00
IUUC-Ame-011681	Astyanax mexicanus	84.58	0.00e+00	3237.00
IUUC-Bta-012838	Bos taurus	96.52	0.00e+00	3595.00
IUUC-Cja-019068	Callithrix jacchus	96.62	0.00e+00	3574.00
IUUC-Cfa-020531	Canis familiaris	96.79	0.00e+00	3623.00
IUUC-Cpo-022304	Cavia porcellus	93.25	0.00e+00	3479.00
IUUC-Csa-023621	Chlorocebus sabaeus	96.02	0.00e+00	3526.00
IUUC-Cho-024944	Choloepus hoffmanni	77.04	0.00e+00	1499.00
IUUC-Dre-028772	Danio rerio	84.42	0.00e+00	3236.00
IUUC-Dno-030063	Dasypus novemcinctus	95.27	0.00e+00	3531.00
IUUC-Dor-030980	Dipodomys ordii	87.30	0.00e+00	1581.00
IUUC-Ete-032554	Echinops telfairi	93.74	0.00e+00	1048.00
IUUC-Eeu-035180	Erinaceus europaeus	79.64	0.00e+00	1472.00
IUUC-Fal-037219	Ficedula albicollis	91.31	0.00e+00	3417.00
IUUC-Gmo-039146	Gadus morhua	79.80	0.00e+00	3042.00
IUUC-Gga-041095	Gallus gallus	90.94	0.00e+00	2382.00
IUUC-Gac-041341	Gasterosteus aculeatus	82.59	0.00e+00	3130.00
IUUC-Hsa-045997	Homo sapiens	97.00	0.00e+00	3582.00
IUUC-Lch-050306	Latimeria chalumnae	84.53	0.00e+00	3175.00
IUUC-Loc-052215	Lepisosteus oculatus	85.02	0.00e+00	3285.00
IUUC-Laf-054044	Loxodonta africana	95.27	0.00e+00	3546.00
IUUC-Mcc-054733	Macaca mulatta	96.95	0.00e+00	3579.00
IUUC-Mga-059666	Meleagris gallopavo	90.11	0.00e+00	3370.00
IUUC-Mmr-060995	Microcebus murinus	97.06	0.00e+00	3573.00
IUUC-Mdo-062482	Monodelphis domestica	93.08	0.00e+00	3483.00
IUUC-Mmu-063533	Mus musculus	95.59	0.00e+00	3521.00
IUUC-Mpu-066704	Mustela putorius furo	97.11	0.00e+00	3616.00
IUUC-Mlu-067592	Myotis lucifugus	96.46	0.00e+00	3570.00
IUUC-Nle-069911	Nomascus leucogenys	96.68	0.00e+00	3564.00
IUUC-Ont-071966	Oreochromis niloticus	84.35	0.00e+00	3234.00
IUUC-Ola-086738	Oryzias latipes	83.38	0.00e+00	3185.00
IUUC-Oga-088436	Otolemur garnettii	93.82	0.00e+00	3475.00
IUUC-Oar-090153	Ovis aries	96.68	0.00e+00	3591.00
IUUC-Ptr-091008	Pan troglodytes	96.68	0.00e+00	3558.00
IUUC-Pan-092404	Papio anubis	96.51	0.00e+00	3556.00
IUUC-Psi-093417	Pelodiscus sinensis	90.97	0.00e+00	3407.00
IUUC-Pfo-096073	Poecilia formosa	84.31	0.00e+00	3236.00
IUUC-Pab-097900	Pongo abelii	96.35	0.00e+00	3561.00
IUUC-Pca-100107	Procavia capensis	81.25	0.00e+00	2543.00
IUUC-Pva-102880	Pteropus vampyrus	92.92	0.00e+00	3384.00
IUUC-Rno-106084	Rattus norvegicus	95.48	0.00e+00	3580.00
IUUC-Sha-106974	Sarcophilus harrisii	93.14	0.00e+00	3486.00
IUUC-Sar-113401	Sorex araneus	85.36	0.00e+00	1832.00
IUUC-Ssc-116057	Sus scrofa	96.96	0.00e+00	3647.00
IUUC-Tru-118444	Takifugu rubripes	82.94	0.00e+00	3161.00
IUUC-Tsy-118941	Tarsius syrichta	84.24	0.00e+00	2687.00
IUUC-Tni-120683	Tetraodon nigroviridis	82.69	0.00e+00	3132.00
IUUC-Tbe-127467	Tupaia belangeri	88.08	0.00e+00	1851.00
IUUC-Ttr-129138	Tursiops truncatus	94.14	0.00e+00	3454.00
IUUC-Vpa-130083	Vicugna pacos	91.12	0.00e+00	3316.00
IUUC-Xtr-131835	Xenopus tropicalis	88.26	0.00e+00	3372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence