iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097724

Ensembl Protein ID

ENSPPYP00000004560.2

UniProt Accession

H2NFM5; H2NFM5_PONAB

Genbank Protein ID

ENSPPYP00000004560

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01037307

Gene Name

UBASH3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000003983.2	ENSPPYT00000004739.2	ENSPPYP00000004560.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.50e-09	36.0	39	76
UBD/SH3	1.00e-21	76.7	255	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++l+ l +MGF+r +a++aL+++ + +++aA+++L+++
   Q: 39   SALDVLLSMGFPRARAQKALASTgGRSVQAACDWLFSH 76
           68999*******************************97 PP

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++e++qv+y+y++qnddeL+l  Gd++++   e+++++egW++g++ ++g++Gl+Pen+++k++
   Q: 255  NHETLQVIYPYTPQNDDELELVPGDFIFMSpmEQTSTSEGWIYGTSLTTGCSGLLPENYITKAD 318
           6899*********************************************************987 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAQYGHPSPL GMAAREELYS KVTPRRNRQQ RPGTIKHGSA LDVLLSMGFP RARAQKALAS 60
TGGRSVQAAC DWLFSHVGDP FLDDPLPREY VLYLRPTGPL AQKLSDFWQQ SKQICGKNKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGGCCAG CCCACAGGGC TCCTTTTCCT TTTTGATCCA TTCAAAAATT ACTCATTGCA 60
AATTCCCGGA CTGCTAGGCG AGGAGAGGGA AGGGGGCGGA GGAGACAGGG CTACTGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50002--SH3
PS50030--UBA

Pfam

PF00300--His_Phos_1
PF14604--SH3_9
PF00627--UBA

SMART

SM00326--SH3
SM00165--UBA

Gene Ontology

GO:0004725--F:protein tyrosine phosphatase activity
GO:0045779--P:negative regulation of bone resorption
GO:0045671--P:negative regulation of osteoclast differentiation
GO:0090331--P:negative regulation of platelet aggregation
GO:0006469--P:negative regulation of protein kinase activity
GO:0009968--P:negative regulation of signal transduction
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002126	Ailuropoda melanoleuca	95.76	0.00e+00	1235.00
IUUC-Apl-004080	Anas platyrhynchos	89.30	0.00e+00	1080.00
IUUC-Aca-004828	Anolis carolinensis	82.64	0.00e+00	1016.00
IUUC-Ame-011030	Astyanax mexicanus	72.19	0.00e+00	800.00
IUUC-Bta-012370	Bos taurus	95.81	0.00e+00	1160.00
IUUC-Cja-018758	Callithrix jacchus	96.01	0.00e+00	1258.00
IUUC-Cfa-020544	Canis familiaris	94.98	0.00e+00	982.00
IUUC-Cpo-022044	Cavia porcellus	96.31	0.00e+00	1159.00
IUUC-Csa-024169	Chlorocebus sabaeus	96.01	0.00e+00	1256.00
IUUC-Cho-024498	Choloepus hoffmanni	77.05	0.00e+00	862.00
IUUC-Cin-025372	Ciona intestinalis	41.27	2.00e-53	203.00
IUUC-Csv-026379	Ciona savignyi	44.19	3.00e-75	275.00
IUUC-Cgl-026592	Colletotrichum gloeosporioides	27.50	6.00e-10	58.20
IUUC-Dre-027539	Danio rerio	72.40	0.00e+00	977.00
IUUC-Dno-029808	Dasypus novemcinctus	94.33	0.00e+00	708.00
IUUC-Dor-030582	Dipodomys ordii	80.00	0.00e+00	1000.00
IUUC-Dme-032201	Drosophila melanogaster	37.26	2.00e-65	243.00
IUUC-Ete-032740	Echinops telfairi	76.89	0.00e+00	993.00
IUUC-Eca-033743	Equus caballus	96.36	0.00e+00	1178.00
IUUC-Eeu-034505	Erinaceus europaeus	82.74	0.00e+00	659.00
IUUC-Fca-036519	Felis catus	95.70	0.00e+00	1266.00
IUUC-Fal-037295	Ficedula albicollis	87.34	0.00e+00	1074.00
IUUC-Gmo-038650	Gadus morhua	70.96	0.00e+00	900.00
IUUC-Gga-040179	Gallus gallus	88.75	0.00e+00	1159.00
IUUC-Gac-042180	Gasterosteus aculeatus	70.72	0.00e+00	911.00
IUUC-Ggo-044581	Gorilla gorilla	96.31	0.00e+00	1260.00
IUUC-Hsa-046526	Homo sapiens	96.16	0.00e+00	1259.00
IUUC-Itr-048502	Ictidomys tridecemlineatus	93.73	3.00e-176	610.00
IUUC-Lch-049576	Latimeria chalumnae	78.40	0.00e+00	983.00
IUUC-Loc-051854	Lepisosteus oculatus	77.22	0.00e+00	900.00
IUUC-Laf-054177	Loxodonta africana	95.62	0.00e+00	1239.00
IUUC-Mcc-055185	Macaca mulatta	96.01	0.00e+00	1256.00
IUUC-Meu-056216	Macropus eugenii	90.26	0.00e+00	1056.00
IUUC-Mga-059564	Meleagris gallopavo	88.94	0.00e+00	1076.00
IUUC-Mmr-060934	Microcebus murinus	95.39	0.00e+00	1251.00
IUUC-Mdo-062955	Monodelphis domestica	93.92	0.00e+00	1203.00
IUUC-Mmu-063301	Mus musculus	95.78	0.00e+00	1245.00
IUUC-Mpu-066416	Mustela putorius furo	96.16	0.00e+00	1271.00
IUUC-Mlu-067833	Myotis lucifugus	86.77	0.00e+00	999.00
IUUC-Nle-069367	Nomascus leucogenys	95.70	0.00e+00	1252.00
IUUC-Opr-070879	Ochotona princeps	82.00	0.00e+00	731.00
IUUC-Ont-072540	Oreochromis niloticus	73.56	0.00e+00	932.00
IUUC-Oan-073124	Ornithorhynchus anatinus	88.12	0.00e+00	856.00
IUUC-Ocu-074796	Oryctolagus cuniculus	95.16	0.00e+00	1223.00
IUUC-Ola-087253	Oryzias latipes	71.67	0.00e+00	930.00
IUUC-Oga-088406	Otolemur garnettii	91.42	0.00e+00	1103.00
IUUC-Oar-090262	Ovis aries	94.93	0.00e+00	1244.00
IUUC-Ptr-091014	Pan troglodytes	96.31	0.00e+00	1260.00
IUUC-Pan-092684	Papio anubis	96.16	0.00e+00	1259.00
IUUC-Psi-093541	Pelodiscus sinensis	89.25	0.00e+00	1165.00
IUUC-Pma-094108	Petromyzon marinus	54.40	1.00e-145	509.00
IUUC-Pfo-097119	Poecilia formosa	71.10	0.00e+00	884.00
IUUC-Pca-100645	Procavia capensis	74.85	0.00e+00	694.00
IUUC-Pva-102322	Pteropus vampyrus	95.98	0.00e+00	1158.00
IUUC-Rno-105148	Rattus norvegicus	94.84	0.00e+00	1235.00
IUUC-Sha-106673	Sarcophilus harrisii	86.34	0.00e+00	1055.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.95	1.00e-08	53.50
IUUC-Sar-113746	Sorex araneus	72.81	2.00e-89	322.00
IUUC-Ssc-116425	Sus scrofa	95.87	0.00e+00	1176.00
IUUC-Tgu-116520	Taeniopygia guttata	87.23	0.00e+00	1119.00
IUUC-Tru-117750	Takifugu rubripes	66.52	0.00e+00	868.00
IUUC-Tsy-118975	Tarsius syrichta	95.98	0.00e+00	1133.00
IUUC-Tni-119830	Tetraodon nigroviridis	71.56	0.00e+00	893.00
IUUC-Tbe-127895	Tupaia belangeri	96.44	4.00e-136	478.00
IUUC-Ttr-129103	Tursiops truncatus	95.70	0.00e+00	1266.00
IUUC-Vpa-130720	Vicugna pacos	98.47	1.00e-113	403.00
IUUC-Xtr-132314	Xenopus tropicalis	82.24	0.00e+00	1081.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence