iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004715

UUCD1 version

UUC-AnC-01001

Ensembl Protein ID

ENSACAP00000009633.3

UniProt Accession

G1KJD4; G1KJD4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009760.3	ENSACAT00000009830.3	ENSACAP00000009633.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-77	259.1	41	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G+kN+g tCY+NS+LQ+L+++pe+re+l++  +e+l   +++++ +     +  +lq+lf++l+  +++a s+ +l++++++  +e  +
   Q: 41   GIKNQGGTCYLNSLLQTLLFTPEFREALFSIGPEELGSLEDTHKPEskvrVIPLQLQRLFAQLLLLDQHAASTADLTDSFGWNGNE--E 127
           9*****************************77777776655333333344899****************************99998..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g+l +qi+c+ec+nvs+r+e+fldl+++
   Q: 128  MRQHDVQELNRILFSALETSL--------------------------VGTSGHNLINQLYHGTLVNQIVCKECKNVSERQEDFLDLTVA 190
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+++L +++++ee++e en y c  c+k++ea k+ kl+klP++L++ L Rf+f+ e++ r k +++++fp++++l+p
   Q: 191  VKDVS-----GLEEALwNMYVEEEHFERENLYRCGACNKLVEAIKSAKLRKLPPFLTVSLLRFNFDFEKCERYKETRCYTFPIQINLKP 274
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc++++ ++  ++ YeL++v++H+G++ +GHY++y+++                                                   
   Q: 275  FCEQTQLDDL-EYMYELFSVIIHKGGCYGGHYHVYIRDidelgnwqvledgslndedkdlketendkekdnpltilknillevestema 362
           ****999887.9***************************************************************************** PP
   S: 302  ......................................................................................ekg 304
                                                                                                 ++ 
   Q: 363  vdclaqkfwekksvswnkkyrkqygpirkylqnnsqdfllssdgskvrlndqshylsfgsqsqshlrnedekmslgkastnlkehfSES 451
           ******************************************************************99999999999998888776677 PP
   S: 305  kWllfdDskVtevkeeevleetg..staYvlfYkr 337
           +W+ ++DskV++++e e++++ +  ++aY+lfY++
   Q: 452  HWFDLNDSKVQPIREREIQKQFQgnESAYMLFYRK 486
           7*******************9889*********98 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MFGDLFDEDF SILSSNQCGK PKSKRKDPEL PNPRENTNLS GIKNQGGTCY LNSLLQTLLF 60
TPEFREALFS IGPEELGSLE DTHKPESKVR VIPLQLQRLF AQLLLLDQHA ASTADLTDSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTGTGTCA TAAATTCGCA ATGTTTGGGG ATTTATTTGA TGAAGACTTC TCTATTTTGT 60
CAAGCAATCA GTGTGGGAAG CCTAAGTCAA AACGCAAAGA TCCTGAACTT CCAAATCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	62.39	0.00e+00	1396.00
IUUC-Apl-004105	Anas platyrhynchos	69.93	0.00e+00	1743.00
IUUC-Ame-011073	Astyanax mexicanus	48.11	0.00e+00	1057.00
IUUC-Bta-012487	Bos taurus	61.48	0.00e+00	1449.00
IUUC-Cja-018937	Callithrix jacchus	63.21	0.00e+00	1492.00
IUUC-Cfa-020645	Canis familiaris	56.82	0.00e+00	867.00
IUUC-Cpo-022160	Cavia porcellus	60.39	0.00e+00	1442.00
IUUC-Csa-023078	Chlorocebus sabaeus	63.10	0.00e+00	1522.00
IUUC-Cho-025013	Choloepus hoffmanni	49.69	9.00e-167	580.00
IUUC-Csv-026193	Ciona savignyi	55.79	1.00e-57	215.00
IUUC-Dre-027416	Danio rerio	49.26	0.00e+00	1120.00
IUUC-Dno-029639	Dasypus novemcinctus	58.76	0.00e+00	1181.00
IUUC-Dor-030624	Dipodomys ordii	74.26	1.00e-125	444.00
IUUC-Ete-032626	Echinops telfairi	49.58	2.00e-164	573.00
IUUC-Eca-034208	Equus caballus	63.18	0.00e+00	1511.00
IUUC-Eeu-035340	Erinaceus europaeus	35.08	1.00e-50	195.00
IUUC-Fca-036006	Felis catus	74.06	2.00e-161	561.00
IUUC-Fal-036925	Ficedula albicollis	69.02	0.00e+00	1614.00
IUUC-Gmo-038597	Gadus morhua	44.92	0.00e+00	907.00
IUUC-Gga-041171	Gallus gallus	69.24	0.00e+00	1696.00
IUUC-Gac-041362	Gasterosteus aculeatus	46.76	0.00e+00	974.00
IUUC-Ggo-045069	Gorilla gorilla	61.27	0.00e+00	1351.00
IUUC-Hsa-046715	Homo sapiens	62.75	0.00e+00	1488.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	60.27	0.00e+00	1399.00
IUUC-Lch-050182	Latimeria chalumnae	51.61	0.00e+00	1129.00
IUUC-Loc-052705	Lepisosteus oculatus	54.29	0.00e+00	1284.00
IUUC-Laf-054132	Loxodonta africana	61.41	0.00e+00	1483.00
IUUC-Mcc-055734	Macaca mulatta	62.86	0.00e+00	1516.00
IUUC-Meu-056135	Macropus eugenii	82.68	7.00e-110	391.00
IUUC-Mga-060092	Meleagris gallopavo	68.14	0.00e+00	1669.00
IUUC-Mmr-061546	Microcebus murinus	59.16	0.00e+00	1395.00
IUUC-Mdo-061935	Monodelphis domestica	57.40	0.00e+00	1377.00
IUUC-Mmu-063630	Mus musculus	59.60	0.00e+00	1435.00
IUUC-Mpu-066579	Mustela putorius furo	60.65	0.00e+00	1491.00
IUUC-Mlu-068034	Myotis lucifugus	61.80	0.00e+00	1436.00
IUUC-Nle-069082	Nomascus leucogenys	58.56	0.00e+00	1184.00
IUUC-Opr-070953	Ochotona princeps	53.74	0.00e+00	721.00
IUUC-Ont-072435	Oreochromis niloticus	47.63	0.00e+00	1107.00
IUUC-Oan-073339	Ornithorhynchus anatinus	63.53	0.00e+00	1466.00
IUUC-Ocu-073760	Oryctolagus cuniculus	61.60	0.00e+00	1468.00
IUUC-Ola-087015	Oryzias latipes	47.19	0.00e+00	937.00
IUUC-Oga-088960	Otolemur garnettii	62.19	0.00e+00	1479.00
IUUC-Oar-089853	Ovis aries	62.06	0.00e+00	1476.00
IUUC-Ptr-091093	Pan troglodytes	62.59	0.00e+00	1490.00
IUUC-Pan-091962	Papio anubis	61.97	0.00e+00	1499.00
IUUC-Psi-093691	Pelodiscus sinensis	72.08	0.00e+00	1793.00
IUUC-Pma-094428	Petromyzon marinus	63.21	1.00e-85	308.00
IUUC-Pfo-096983	Poecilia formosa	48.07	0.00e+00	1034.00
IUUC-Pab-097860	Pongo abelii	61.70	0.00e+00	1362.00
IUUC-Pca-100514	Procavia capensis	60.53	3.00e-138	486.00
IUUC-Pva-102771	Pteropus vampyrus	60.81	0.00e+00	1361.00
IUUC-Rno-105405	Rattus norvegicus	59.26	0.00e+00	1431.00
IUUC-Sha-107376	Sarcophilus harrisii	58.41	0.00e+00	1332.00
IUUC-Ssc-115819	Sus scrofa	56.53	0.00e+00	989.00
IUUC-Tgu-117262	Taeniopygia guttata	68.43	0.00e+00	1690.00
IUUC-Tru-117601	Takifugu rubripes	47.81	0.00e+00	1091.00
IUUC-Tsy-118996	Tarsius syrichta	53.84	0.00e+00	1112.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.12	0.00e+00	848.00
IUUC-Tbe-127616	Tupaia belangeri	49.68	0.00e+00	804.00
IUUC-Ttr-129075	Tursiops truncatus	59.49	0.00e+00	1368.00
IUUC-Vpa-130108	Vicugna pacos	62.09	0.00e+00	1332.00
IUUC-Xtr-132623	Xenopus tropicalis	53.28	0.00e+00	1202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence