iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004105

Ensembl Protein ID

ENSAPLP00000014143.1

UniProt Accession

U3J3R6; U3J3R6_ANAPL

Genbank Protein ID

ENSAPLP00000014143

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01091119

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000014274.1	ENSAPLT00000014917.1	ENSAPLP00000014143.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-76	256.8	42	493

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelr..elllekkkeklneenp....kepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           G+kN+g tCY+NS+LQ+L+++pe+r  e+l++  +e+l   ++    + +   +  +lq+lf++l+  +++a s+++l++++++ ++e 
   Q: 42   GIKNQGGTCYLNSLLQTLLFTPEFRvaEALFSLGPEELGTLDDinkpDAKVRIIPLQLQRLFAQLLLLDQQAASTTDLTESFGWNSNE- 129
           9***********************84467777666666655442222444458899***************************99998. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            +++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+n+s+r+e+fldl+
   Q: 130  -EMRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTVVNQIVCKECKNISERQEDFLDLT 191
           .**********************..........................789************************************* PP
   S: 174  lpvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           ++v+g        l+++L +++++ee +e+en y c  c+k++ea+k+ kl+klP++L++ L Rf+f+ e++ r k +++++fp++++l
   Q: 192  VAVKGVA-----GLDEALwNMYVEEEYFENENLYRCGACDKLVEASKSAKLRKLPPFLTISLLRFNFDFEKCERYKETSCYTFPIQINL 275
           *******.....9**************************************************************************** PP
   S: 262  spfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................. 301
           +pfc+++e ++ +++ YeL++v++H+G++ +GHY++y+k+                                                 
   Q: 276  RPFCEQTEMDD-SEYMYELFSVIIHKGGCYGGHYHVYIKDvdelgnwqlqededrliedkalrenenakeaenplavlkgilseeeskq 363
           ******77766.5**************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 364  ipvdqlgqkllekkkvswnkkyrkqygalrkylqnhpqifqfspdknkvglkekyklpfksdsqgldlqspsqkndiqwnlektptrle 452
           ******************************************************************99999999999999988888775 PP
   S: 302  .ekgk....WllfdDskVtevkeeevleetg..staYvlfYkr 337
            +  +    W+ ++DskV+++kee+++++ +  ++aY+lfY++
   Q: 453  eT--SvgchWFDLNDSKVQPIKEEDIEQQFQgkESAYMLFYRK 493
           41..24567*******************9889*********98 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MFGDLFEEDF SFISNNHCGK GKKSKPRDSE PPAPRDFTNL SGIKNQGGTC YLNSLLQTLL 60
FTPEFRVAEA LFSLGPEELG TLDDINKPDA KVRIIPLQLQ RLFAQLLLLD QQAASTTDLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGGG ACTTATTTGA AGAGGATTTT TCCTTTATTT CAAACAATCA TTGCGGAAAA 60
GGGAAGAAAT CAAAGCCCAG AGATTCTGAG CCTCCAGCTC CCAGAGACTT CACCAACCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	63.77	0.00e+00	1448.00
IUUC-Aca-004715	Anolis carolinensis	69.93	0.00e+00	1721.00
IUUC-Ame-011073	Astyanax mexicanus	49.22	0.00e+00	1090.00
IUUC-Bta-012487	Bos taurus	63.09	0.00e+00	1492.00
IUUC-Cja-018937	Callithrix jacchus	64.47	0.00e+00	1549.00
IUUC-Cfa-020645	Canis familiaris	56.67	0.00e+00	872.00
IUUC-Cpo-022160	Cavia porcellus	61.93	0.00e+00	1487.00
IUUC-Csa-023078	Chlorocebus sabaeus	64.62	0.00e+00	1572.00
IUUC-Cho-025013	Choloepus hoffmanni	50.63	3.00e-169	588.00
IUUC-Csv-026193	Ciona savignyi	56.54	1.00e-59	222.00
IUUC-Dre-027416	Danio rerio	50.97	0.00e+00	1186.00
IUUC-Dno-029639	Dasypus novemcinctus	60.09	0.00e+00	1199.00
IUUC-Dor-030624	Dipodomys ordii	78.22	5.00e-131	462.00
IUUC-Ete-032626	Echinops telfairi	52.44	8.00e-176	610.00
IUUC-Eca-034208	Equus caballus	64.61	0.00e+00	1550.00
IUUC-Eeu-035340	Erinaceus europaeus	35.66	8.00e-55	208.00
IUUC-Fca-036006	Felis catus	76.19	8.00e-170	589.00
IUUC-Fal-036925	Ficedula albicollis	87.03	0.00e+00	2067.00
IUUC-Gmo-038597	Gadus morhua	44.41	0.00e+00	905.00
IUUC-Gga-041171	Gallus gallus	90.30	0.00e+00	2264.00
IUUC-Gac-041362	Gasterosteus aculeatus	55.64	0.00e+00	679.00
IUUC-Ggo-045069	Gorilla gorilla	62.75	0.00e+00	1381.00
IUUC-Hsa-046715	Homo sapiens	64.25	0.00e+00	1527.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	62.38	0.00e+00	1445.00
IUUC-Lch-050182	Latimeria chalumnae	52.98	0.00e+00	1167.00
IUUC-Loc-052705	Lepisosteus oculatus	55.47	0.00e+00	1334.00
IUUC-Laf-054132	Loxodonta africana	63.79	0.00e+00	1550.00
IUUC-Mcc-055734	Macaca mulatta	64.46	0.00e+00	1561.00
IUUC-Meu-056135	Macropus eugenii	84.98	6.00e-114	405.00
IUUC-Mga-060092	Meleagris gallopavo	88.70	0.00e+00	2213.00
IUUC-Mmr-061546	Microcebus murinus	60.46	0.00e+00	1413.00
IUUC-Mdo-061935	Monodelphis domestica	59.84	0.00e+00	1454.00
IUUC-Mmu-063630	Mus musculus	62.32	0.00e+00	1514.00
IUUC-Mpu-066579	Mustela putorius furo	62.61	0.00e+00	1547.00
IUUC-Mlu-068034	Myotis lucifugus	62.21	0.00e+00	1468.00
IUUC-Nle-069082	Nomascus leucogenys	59.87	0.00e+00	1214.00
IUUC-Opr-070953	Ochotona princeps	53.84	0.00e+00	716.00
IUUC-Ont-072435	Oreochromis niloticus	48.17	0.00e+00	1120.00
IUUC-Oan-073339	Ornithorhynchus anatinus	66.14	0.00e+00	1552.00
IUUC-Ocu-073760	Oryctolagus cuniculus	62.76	0.00e+00	1494.00
IUUC-Ola-087015	Oryzias latipes	47.94	0.00e+00	950.00
IUUC-Oga-088960	Otolemur garnettii	64.22	0.00e+00	1523.00
IUUC-Oar-089853	Ovis aries	63.66	0.00e+00	1518.00
IUUC-Ptr-091093	Pan troglodytes	64.49	0.00e+00	1538.00
IUUC-Pan-091962	Papio anubis	63.69	0.00e+00	1545.00
IUUC-Psi-093691	Pelodiscus sinensis	79.66	0.00e+00	1989.00
IUUC-Pma-094428	Petromyzon marinus	63.93	6.00e-89	320.00
IUUC-Pfo-096983	Poecilia formosa	47.85	0.00e+00	1025.00
IUUC-Pab-097860	Pongo abelii	62.88	0.00e+00	1400.00
IUUC-Pca-100514	Procavia capensis	55.76	1.00e-148	520.00
IUUC-Pva-102771	Pteropus vampyrus	62.97	0.00e+00	1400.00
IUUC-Rno-105405	Rattus norvegicus	61.23	0.00e+00	1498.00
IUUC-Sha-107376	Sarcophilus harrisii	61.71	0.00e+00	1432.00
IUUC-Ssc-115819	Sus scrofa	58.31	0.00e+00	997.00
IUUC-Tgu-117262	Taeniopygia guttata	86.23	0.00e+00	2182.00
IUUC-Tru-117601	Takifugu rubripes	48.07	0.00e+00	1085.00
IUUC-Tsy-118996	Tarsius syrichta	55.35	0.00e+00	1153.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.77	0.00e+00	870.00
IUUC-Tbe-127616	Tupaia belangeri	50.84	0.00e+00	819.00
IUUC-Ttr-129075	Tursiops truncatus	61.78	0.00e+00	1410.00
IUUC-Vpa-130108	Vicugna pacos	62.74	0.00e+00	1340.00
IUUC-Xtr-132623	Xenopus tropicalis	55.13	0.00e+00	1283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence