iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050182

Ensembl Protein ID

ENSLACP00000015499.1

UniProt Accession

H3B0S8; H3B0S8_LATCH

Genbank Protein ID

ENSLACP00000015499

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01069878

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000013647.1	ENSLACT00000015607.1	ENSLACP00000015499.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.10e-75	253.3	44	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkekl....neenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G+ N+g tCY+NS+LQ+L+++pe+re+l++  +e+l    +eenp+++   +  +lq+lf++l+  +++a s+ +l+++++++++e  +
   Q: 44   GIANQGGTCYLNSLLQTLLFTPEFREALFSLGEEDLgclaDEENPDSRVRVIPLQLQRLFAQLLLVDQQAASTANLTDSFGWTSNE--E 130
           99****************************55444411224556677777999*******************************98..9 PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
            +q+D+qE+ ++l+++le++l                            +++++li++l++g + ++i c+ec+nvs+r+e+fldl+++
   Q: 131  RSQHDVQELNRILFSALESSL--------------------------VGTSGHDLINRLYHGAVVNKISCEECGNVSERQEDFLDLTVA 193
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +     sl+++L +++++ee +++en y c+ c+k+++a k+ kl+klP +L++ L Rf+f+   ++r k   +++fpl+++l+p
   Q: 194  VKDVS-----SLEEALwNMYVEEEYFDNENLYRCSACNKLVKAAKSAKLRKLPLFLTISLLRFNFDFVACQRYKEMGRYTFPLQINLQP 277
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc++ e +++ ++ YeL++v++H+G++ +GHY++y+k+                                                   
   Q: 278  FCEQGELADS-EYLYELFSVIIHKGGCYGGHYHVYIKDldqlgtwypqddmmkqvpsekdaedsvklmemedpslvlsvliaqenvflp 365
           ****888875.9***************************************************************************** PP
   S: 302  ......................................................................................ekg 304
                                                                                                    
   Q: 366  ilglaqspvasvtvrwnvhlrffpgwqgkfllnhpetfvlssdrnwvslkpsgtetwdpqpnqrssaaadpastqscktqgsanakF-- 452
           **************************************************************9999999999999988877766441.. PP
   S: 305  k...WllfdDskVtevkeeevleetg..staYvlfYkr 337
               W+ f+DskV++++e++++++ +  ++aY+lfY++
   Q: 453  TcshWFDFNDSKVQPIQEKDIEKQFQgkESAYMLFYRQ 490
           1556*******************9889*********97 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MFGDLFEEED DSPFVLNDKG LSGQRSGFKE LVPPAPRGAA KLSGIANQGG TCYLNSLLQT 60
LLFTPEFREA LFSLGEEDLG CLADEENPDS RVRVIPLQLQ RLFAQLLLVD QQAASTANLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGGG ATCTGTTTGA GGAAGAGGAC GACTCCCCAT TTGTGCTGAA TGATAAAGGT 60
TTAAGTGGGC AGAGGTCAGG GTTCAAGGAA TTGGTACCGC CGGCTCCCAG GGGAGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	51.59	0.00e+00	1061.00
IUUC-Apl-004105	Anas platyrhynchos	52.98	0.00e+00	1183.00
IUUC-Aca-004715	Anolis carolinensis	51.69	0.00e+00	1129.00
IUUC-Ame-011073	Astyanax mexicanus	46.58	0.00e+00	972.00
IUUC-Bta-012487	Bos taurus	52.61	0.00e+00	1156.00
IUUC-Cja-018937	Callithrix jacchus	52.33	0.00e+00	1147.00
IUUC-Cfa-020645	Canis familiaris	45.01	2.00e-169	589.00
IUUC-Cpo-022160	Cavia porcellus	51.62	0.00e+00	1113.00
IUUC-Csa-023078	Chlorocebus sabaeus	52.46	0.00e+00	1180.00
IUUC-Cho-025013	Choloepus hoffmanni	78.09	1.00e-109	391.00
IUUC-Csv-026193	Ciona savignyi	51.25	8.00e-55	206.00
IUUC-Dre-027416	Danio rerio	48.53	0.00e+00	1062.00
IUUC-Dno-029639	Dasypus novemcinctus	49.16	0.00e+00	887.00
IUUC-Dor-030624	Dipodomys ordii	67.11	3.00e-108	386.00
IUUC-Ete-032626	Echinops telfairi	42.95	4.00e-113	402.00
IUUC-Eca-034208	Equus caballus	52.85	0.00e+00	1174.00
IUUC-Eeu-035340	Erinaceus europaeus	35.04	2.00e-43	171.00
IUUC-Fca-036006	Felis catus	65.12	6.00e-136	476.00
IUUC-Fal-036925	Ficedula albicollis	54.06	0.00e+00	1123.00
IUUC-Gmo-038597	Gadus morhua	45.58	0.00e+00	838.00
IUUC-Gga-041171	Gallus gallus	53.43	0.00e+00	1187.00
IUUC-Gac-041362	Gasterosteus aculeatus	48.29	0.00e+00	905.00
IUUC-Ggo-045069	Gorilla gorilla	51.43	0.00e+00	1036.00
IUUC-Hsa-046715	Homo sapiens	52.82	0.00e+00	1165.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	50.39	0.00e+00	1077.00
IUUC-Loc-052705	Lepisosteus oculatus	53.64	0.00e+00	1239.00
IUUC-Laf-054132	Loxodonta africana	53.17	0.00e+00	1167.00
IUUC-Mcc-055734	Macaca mulatta	52.58	0.00e+00	1181.00
IUUC-Meu-056135	Macropus eugenii	82.17	2.00e-106	380.00
IUUC-Mga-060092	Meleagris gallopavo	53.49	0.00e+00	1181.00
IUUC-Mmr-061546	Microcebus murinus	51.00	0.00e+00	1058.00
IUUC-Mdo-061935	Monodelphis domestica	50.12	0.00e+00	1140.00
IUUC-Mmu-063630	Mus musculus	49.92	0.00e+00	1097.00
IUUC-Mpu-066579	Mustela putorius furo	51.18	0.00e+00	1160.00
IUUC-Mlu-068034	Myotis lucifugus	51.95	0.00e+00	1121.00
IUUC-Nle-069082	Nomascus leucogenys	48.39	0.00e+00	885.00
IUUC-Opr-070953	Ochotona princeps	42.80	1.00e-134	474.00
IUUC-Ont-072435	Oreochromis niloticus	46.99	0.00e+00	1030.00
IUUC-Oan-073339	Ornithorhynchus anatinus	52.73	0.00e+00	1145.00
IUUC-Ocu-073760	Oryctolagus cuniculus	51.86	0.00e+00	1143.00
IUUC-Ola-087015	Oryzias latipes	48.48	0.00e+00	868.00
IUUC-Oga-088960	Otolemur garnettii	51.38	0.00e+00	1128.00
IUUC-Oar-089853	Ovis aries	52.53	0.00e+00	1174.00
IUUC-Ptr-091093	Pan troglodytes	52.89	0.00e+00	1164.00
IUUC-Pan-091962	Papio anubis	52.67	0.00e+00	1179.00
IUUC-Psi-093691	Pelodiscus sinensis	54.03	0.00e+00	1207.00
IUUC-Pma-094428	Petromyzon marinus	62.54	3.00e-86	311.00
IUUC-Pfo-096983	Poecilia formosa	47.38	0.00e+00	943.00
IUUC-Pab-097860	Pongo abelii	51.60	0.00e+00	1065.00
IUUC-Pca-100514	Procavia capensis	51.66	1.00e-114	407.00
IUUC-Pva-102771	Pteropus vampyrus	51.69	0.00e+00	1051.00
IUUC-Rno-105405	Rattus norvegicus	50.59	0.00e+00	1107.00
IUUC-Sha-107376	Sarcophilus harrisii	49.79	0.00e+00	1073.00
IUUC-Ssc-115819	Sus scrofa	45.80	0.00e+00	678.00
IUUC-Tgu-117262	Taeniopygia guttata	53.63	0.00e+00	1192.00
IUUC-Tru-117601	Takifugu rubripes	47.25	0.00e+00	1022.00
IUUC-Tsy-118996	Tarsius syrichta	42.56	8.00e-161	561.00
IUUC-Tni-120682	Tetraodon nigroviridis	41.47	0.00e+00	765.00
IUUC-Tbe-127616	Tupaia belangeri	42.76	6.00e-120	425.00
IUUC-Ttr-129075	Tursiops truncatus	50.54	0.00e+00	1053.00
IUUC-Vpa-130108	Vicugna pacos	51.42	0.00e+00	1001.00
IUUC-Xtr-132623	Xenopus tropicalis	48.03	0.00e+00	1039.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence