iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072881

UUCD1 version

UUC-OrA-00759

Ensembl Protein ID

ENSOANP00000008610.1

UniProt Accession

F6Q167; F6Q167_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000005415.2	ENSOANT00000008612.2	ENSOANP00000008610.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.40e-53	179.3	8	132
UBD/UBC-like/UBD_UBC	9.60e-78	259.2	8	133

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++W
   Q: 8    KELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQW 93
           8********************.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknre 131
           spal++++vllsi+sll++pnp++pl  e+a+++k++re
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRE 132
           *************************************98 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
           kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+a
   Q: 8    KELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPA 96
           9**************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkek 129
           lt+skvlls+csll+d++pddplv+eiariyktd+ek
   Q: 97   LTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREK 133
           ***********************************97 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

TPLPSFLKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCCCCTAC CCTCCTTTCT GAAGGAGCTG AATGACCTGG CCCGGGACCC ACCAGCACAG 60
TGTTCGGCAG GTCCCGTCGG AGATGACAGT AAGTACCCCC GCCACCCCCT CCCCCGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Lch-050583	Latimeria chalumnae	98.41	3.00e-71	259.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence