iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	95.20	2.00e-102	369.00	IUUC-Hsa-046919

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAMSSFLINS NYVDPKFPPC EEYSQSDYLP SDHSPGYYAG GQRRESGFQP EAAFGRRAPC 60
TVQRYAACRD PGPPPPPPPP PPPPPPGLSP RAPVQSTAGA LLPEPGQRSE VVSSSPPPPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAATAAA CCTCTTTGGC TGGAGTAGGG TCCGGGTGAG CAGATTTCCT TATCCGGGAA 60
TCGCAGGCCG GGTGGCCATT GGCTCGGAGG ATCACGTGGG CCTCTAACTT TGTTCACTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR009057--Homeobox-like
IPR017995--Homeobox_antennapedia
IPR001827--Homeobox_Antennapedia_CS
IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa

PROSITE

PS00032--ANTENNAPEDIA
PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2

Pfam

PF00046--Homeobox

PRINTS

PR00025--ANTENNAPEDIA
PR00024--HOMEOBOX

SMART

SM00389--HOX

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0009952--P:anterior/posterior pattern specification
GO:0048539--P:bone marrow development
GO:0008283--P:cell proliferation
GO:0060216--P:definitive hemopoiesis
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0060218--P:hematopoietic stem cell differentiation
GO:0002011--P:morphogenesis of an epithelial sheet
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:2000738--P:positive regulation of stem cell differentiation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0048103--P:somatic stem cell division
GO:0048536--P:spleen development

KEGG

rno:497988

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002156	Ailuropoda melanoleuca	63.03	4.00e-73	267.00
IUUC-Aca-004281	Anolis carolinensis	69.26	2.00e-76	278.00
IUUC-Ame-011424	Astyanax mexicanus	65.94	1.00e-71	262.00
IUUC-Bta-013580	Bos taurus	91.30	1.00e-102	365.00
IUUC-Bdi-014316	Brachypodium distachyon	47.54	1.00e-09	57.40
IUUC-Bra-017918	Brassica rapa	49.15	1.00e-09	57.00
IUUC-Cja-019422	Callithrix jacchus	87.22	1.00e-99	355.00
IUUC-Cfa-020551	Canis familiaris	88.46	2.00e-106	377.00
IUUC-Cpo-022099	Cavia porcellus	97.56	2.00e-63	234.00
IUUC-Csa-023337	Chlorocebus sabaeus	89.08	3.00e-100	357.00
IUUC-Dre-027947	Danio rerio	65.95	4.00e-74	270.00
IUUC-Dno-029094	Dasypus novemcinctus	88.16	4.00e-99	353.00
IUUC-Dme-031651	Drosophila melanogaster	29.82	9.80e-01	30.80
IUUC-Fca-035652	Felis catus	100.00	1.00e-61	228.00
IUUC-Gac-041606	Gasterosteus aculeatus	62.03	5.00e-69	254.00
IUUC-Hsa-046919	Homo sapiens	89.04	1.00e-99	355.00
IUUC-Itr-048677	Ictidomys tridecemlineatus	94.83	4.00e-112	397.00
IUUC-Lch-050353	Latimeria chalumnae	67.97	1.00e-74	272.00
IUUC-Laf-053406	Loxodonta africana	89.57	2.00e-103	368.00
IUUC-Meu-056129	Macropus eugenii	85.53	6.00e-105	373.00
IUUC-Mdo-062656	Monodelphis domestica	84.72	1.00e-103	369.00
IUUC-Mmu-064317	Mus musculus	99.13	6.00e-117	413.00
IUUC-Mpu-066715	Mustela putorius furo	89.57	1.00e-101	362.00
IUUC-Nle-069403	Nomascus leucogenys	88.16	2.00e-99	354.00
IUUC-Ont-072022	Oreochromis niloticus	62.03	4.00e-68	250.00
IUUC-Oan-073355	Ornithorhynchus anatinus	77.63	5.00e-90	323.00
IUUC-Obr-076254	Oryza brachyantha	45.00	5.00e-08	51.60
IUUC-Oga-089067	Otolemur garnettii	89.96	6.00e-102	363.00
IUUC-Oar-089454	Ovis aries	76.75	4.00e-96	343.00
IUUC-Ptr-091405	Pan troglodytes	89.04	1.00e-99	355.00
IUUC-Pan-092634	Papio anubis	89.08	3.00e-100	357.00
IUUC-Psi-093940	Pelodiscus sinensis	71.00	8.00e-79	286.00
IUUC-Pfo-097180	Poecilia formosa	58.54	4.00e-63	234.00
IUUC-Pab-097837	Pongo abelii	89.04	1.00e-99	355.00
IUUC-Pva-102648	Pteropus vampyrus	94.35	2.00e-106	378.00
IUUC-Sha-107548	Sarcophilus harrisii	85.09	5.00e-104	370.00
IUUC-Sly-111303	Solanum lycopersicum	44.29	1.00e-08	53.90
IUUC-Ssc-116419	Sus scrofa	89.47	2.00e-100	358.00
IUUC-Tru-118619	Takifugu rubripes	61.92	2.00e-69	255.00
IUUC-Tni-120889	Tetraodon nigroviridis	60.92	1.00e-68	252.00
IUUC-Ttr-128475	Tursiops truncatus	88.70	5.00e-101	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence