iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054211

Ensembl Protein ID

ENSLAFP00000013590.4

UniProt Accession

G3TGI3; G3TGI3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016193.4	ENSLAFT00000016190.4	ENSLAFP00000013590.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-13	51.2	367	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve 
   Q: 367  RVRALYDYAGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRIGLYPANYVEC 421
           699********************9999.999********7.99************86 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAPEEEAGGE ALGGSFWEAG NYRQTVQRVE DGYRLCGDLV SCFQERARIE KAYAQQLADW 60
ARKWRGAVEK GPQYGTLEKA WHAFFTAAER LSALHLEVRE KLQGQDSDRV RAWQRGAFHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCAG AGGAAGAGGC TGGAGGGGAG GCCCTAGGAG GCAGTTTCTG GGAGGTGAGC 60
AGCTGGGTCC CGGTTGTGGG AGGTGGCACT GAAATGCCCA CCAGTCTTAG GGCTGAGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	93.09	0.00e+00	639.00
IUUC-Apl-003211	Anas platyrhynchos	64.19	3.00e-179	620.00
IUUC-Aca-004256	Anolis carolinensis	64.18	6.00e-175	606.00
IUUC-Ame-011049	Astyanax mexicanus	60.14	3.00e-152	531.00
IUUC-Bta-013322	Bos taurus	90.21	0.00e+00	758.00
IUUC-Cja-018907	Callithrix jacchus	94.34	0.00e+00	800.00
IUUC-Cfa-021126	Canis familiaris	92.69	0.00e+00	784.00
IUUC-Cpo-021491	Cavia porcellus	91.27	0.00e+00	781.00
IUUC-Csa-023107	Chlorocebus sabaeus	94.81	0.00e+00	799.00
IUUC-Dre-027933	Danio rerio	60.41	2.00e-146	512.00
IUUC-Dno-029002	Dasypus novemcinctus	93.87	0.00e+00	765.00
IUUC-Eca-033824	Equus caballus	93.63	0.00e+00	796.00
IUUC-Eeu-035122	Erinaceus europaeus	84.42	1.00e-171	595.00
IUUC-Fca-036420	Felis catus	93.87	0.00e+00	802.00
IUUC-Fal-037277	Ficedula albicollis	63.68	1.00e-180	625.00
IUUC-Gga-040941	Gallus gallus	64.55	4.00e-179	620.00
IUUC-Gac-041374	Gasterosteus aculeatus	59.39	2.00e-135	475.00
IUUC-Ggo-045211	Gorilla gorilla	94.34	0.00e+00	795.00
IUUC-Hsa-046053	Homo sapiens	94.81	0.00e+00	799.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	93.16	0.00e+00	787.00
IUUC-Loc-052808	Lepisosteus oculatus	61.36	8.00e-155	540.00
IUUC-Mcc-055044	Macaca mulatta	94.81	0.00e+00	799.00
IUUC-Mga-059216	Meleagris gallopavo	64.49	1.00e-179	622.00
IUUC-Mmr-061172	Microcebus murinus	94.58	0.00e+00	804.00
IUUC-Mdo-062600	Monodelphis domestica	86.56	0.00e+00	758.00
IUUC-Mmu-063218	Mus musculus	92.92	0.00e+00	791.00
IUUC-Mpu-066819	Mustela putorius furo	93.39	0.00e+00	641.00
IUUC-Mlu-067597	Myotis lucifugus	89.56	0.00e+00	771.00
IUUC-Nle-069195	Nomascus leucogenys	94.58	0.00e+00	797.00
IUUC-Opr-071050	Ochotona princeps	91.53	0.00e+00	758.00
IUUC-Ont-071612	Oreochromis niloticus	55.41	5.00e-139	487.00
IUUC-Oan-073256	Ornithorhynchus anatinus	86.85	0.00e+00	732.00
IUUC-Ocu-074653	Oryctolagus cuniculus	94.10	0.00e+00	767.00
IUUC-Oga-089040	Otolemur garnettii	92.45	0.00e+00	796.00
IUUC-Oar-089918	Ovis aries	93.41	0.00e+00	771.00
IUUC-Ptr-091307	Pan troglodytes	94.81	0.00e+00	799.00
IUUC-Pan-092512	Papio anubis	94.81	0.00e+00	799.00
IUUC-Pfo-096881	Poecilia formosa	61.25	3.00e-151	527.00
IUUC-Pab-098620	Pongo abelii	94.81	0.00e+00	799.00
IUUC-Pva-102464	Pteropus vampyrus	91.27	0.00e+00	770.00
IUUC-Rno-106091	Rattus norvegicus	91.75	0.00e+00	782.00
IUUC-Sha-107474	Sarcophilus harrisii	86.56	0.00e+00	755.00
IUUC-Ssc-116128	Sus scrofa	93.63	0.00e+00	798.00
IUUC-Tgu-117511	Taeniopygia guttata	69.97	7.00e-148	516.00
IUUC-Tru-118005	Takifugu rubripes	59.73	1.00e-139	489.00
IUUC-Tni-119851	Tetraodon nigroviridis	64.73	3.00e-138	484.00
IUUC-Ttr-129313	Tursiops truncatus	93.16	0.00e+00	795.00
IUUC-Vpa-130760	Vicugna pacos	94.54	7.00e-99	353.00
IUUC-Xtr-132697	Xenopus tropicalis	56.48	3.00e-137	481.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence