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Tag Content
UUCD2 ID IUUC-Xtr-132810
UUCD1 version UUC-XeT-00869
Ensembl Protein ID ENSXETP00000059630.1
UniProt Accession Q0D2D8; Q0D2D8_XENTR
Genbank Protein ID AAI21942.1
Protein Name Cullin 5
Genbank Nucleotide ID AAMC01039068
Gene Name cul5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000034081.1 ENSXETT00000060449.1 ENSXETP00000059630.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 8.90e-230 764.7 22 672
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk..vgaklYkklkevleefikqvkkkveesedeq.lLktynreWekfreqlkvlrki 86
           +r +v k+lrqesv k+++ +l+++v+++cl++  + ak++++lke++ +fikq++++v +++d++ lLk+y++eW+kf++q+++l+k+
   Q: 22   MRPIVLKLLRQESVtKQQWFDLFSDVHAVCLWDdkGPAKIHQALKEDILDFIKQAQARVLSHQDDTaLLKAYIVEWRKFFTQCDILPKP 110
           7899****************************9999***************************************************** PP
   S: 87   fayldrtyvkk.....skkv..sevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk...laiyk 165
           f++l+ t ++k     +++v  s vrkL+ld+w+++i+++ik+rl+++++kl++aeR gea+d++l+ gv+es+v+L++n    l+iy+
   Q: 111  FCQLEITLMGKqgsnkKSNVedSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPedkLQIYR 199
           ***********8765544448899*******************************************************99999***** PP
   S: 166  esFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetk....Llevvekeliakhlesllaelvallrdk 250
           ++FE+++l++t++fy++++ ++lq+n+v++Y+k+++a+l+eee+ra ryle+++e++    L+e+++++l++++ e++lae++ +++++
   Q: 200  DNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEENRALRYLETRRECNsvqaLMECCVNALVTSFKETILAECQGMIKRN 288
           *******************************************************999999**************************** PP
   S: 251  ktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfv 337
           +te+l++m++L+++v+ng+e++lk+le+hi ++g+a+++  ae++++d++kyVe+ll+l+n+++klv+eaF++d++Fl+a+dka++++v
   Q: 289  ETEKLHLMFSLMDKVPNGIEPMLKDLEEHIVSAGLADMVaaAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVV 377
           **************************************99999********************************************** PP
   S: 338  nknsvlka................akspEllAryiDqlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgk 408
           n+++++k+                +k+pEllA+y+D+lLrk+  sk+lt+ee+ea+l++vllv+ky+++kdvF++y+k hL++RL++++
   Q: 378  NDATIFKLelplkqkgvglktqpeSKCPELLANYCDMLLRKTplSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDI 466
           ***************************************************************************************** PP
   S: 409  sasseaEesviekLkeec.gaeftskLerMfqdlkvSedlnrqFk.eekenteesesvelsvlvLsagaWptasetekvsLPaelekti 495
           sa+se+Ee+++e+L+e++ +a++++kL+rMfqd+kvSedln++Fk ++k+n+ + +++++++++L+agaW+++se++ vsLP+ele++i
   Q: 467  SADSEIEENMVEWLREVGmPADYVNKLARMFQDIKVSEDLNQAFKeMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLI 555
           *********************************************5688888899********************************** PP
   S: 496  ekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk.. 579
           +++eefY+++hsgRkL+W+h ++++ +++++++g+y+l+V+tfQ+avL+a+n++  ek+s+e+lk atelp++eLrrtl+sLv+ +k  
   Q: 556  PEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRprEKISFENLKLATELPDAELRRTLWSLVAfPKlk 644
           *****************************************************999****************************99999 PP
   S: 580  kqvlkkepeske...ieeedlfsvNqef 604
           +qvl +ep  ++   ++e++lfsvNqef
   Q: 645  RQVLSYEPTVNSpkdFTEGTLFSVNQEF 672
           9********977777************9 PP
   
Organism Xenopus tropicalis
Protein Sequence
(Fasta)
MATSNLLKNK GSLQFEDKWD FMRPIVLKLL RQESVTKQQW FDLFSDVHAV CLWDDKGPAK 60
IHQALKEDIL DFIKQAQARV LSHQDDTALL KAYIVEWRKF FTQCDILPKP FCQLEITLMG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132810|E3,Cullin|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCGGGAAGA CAAGTTGAGG GAACATGGCG ACGTCTAATT TGTTAAAGGT AAGAGGAGCC 60
ACCTCTCTGT ACTGTCCGCT GCTCGTATGC CGTGGGAGGT CGGGACACAC AGCCCAGCCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132810|E3,Cullin|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG xtr:780297
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002082 Ailuropoda melanoleuca 97.69 0.00e+00 1539.00
IUUC-Apl-003564 Anas platyrhynchos 99.22 0.00e+00 1546.00
IUUC-Aca-004319 Anolis carolinensis 98.97 0.00e+00 1558.00
IUUC-Ame-011742 Astyanax mexicanus 97.18 0.00e+00 1533.00
IUUC-Bta-012515 Bos taurus 98.81 0.00e+00 1514.00
IUUC-Cel-018522 Caenorhabditis elegans 51.61 0.00e+00 761.00
IUUC-Cja-018785 Callithrix jacchus 98.72 0.00e+00 1556.00
IUUC-Cfa-020932 Canis familiaris 98.68 0.00e+00 1512.00
IUUC-Cpo-022317 Cavia porcellus 98.59 0.00e+00 1555.00
IUUC-Csa-023949 Chlorocebus sabaeus 98.85 0.00e+00 1558.00
IUUC-Cho-024570 Choloepus hoffmanni 98.14 2.00e-126 446.00
IUUC-Cin-025540 Ciona intestinalis 73.30 8.00e-152 529.00
IUUC-Csv-025978 Ciona savignyi 65.32 0.00e+00 1007.00
IUUC-Dre-027958 Danio rerio 96.92 0.00e+00 1543.00
IUUC-Dno-029195 Dasypus novemcinctus 98.58 0.00e+00 1546.00
IUUC-Dor-030573 Dipodomys ordii 86.38 2.00e-171 596.00
IUUC-Dme-032083 Drosophila melanogaster 67.98 0.00e+00 920.00
IUUC-Ete-032428 Echinops telfairi 81.54 0.00e+00 1223.00
IUUC-Eca-033232 Equus caballus 98.72 0.00e+00 1555.00
IUUC-Eeu-035348 Erinaceus europaeus 98.71 0.00e+00 748.00
IUUC-Fca-035401 Felis catus 98.19 0.00e+00 1519.00
IUUC-Fal-037514 Ficedula albicollis 99.09 0.00e+00 1544.00
IUUC-Gmo-038577 Gadus morhua 94.51 0.00e+00 1498.00
IUUC-Gga-041096 Gallus gallus 98.97 0.00e+00 1546.00
IUUC-Gac-042108 Gasterosteus aculeatus 95.40 0.00e+00 1512.00
IUUC-Ggo-045313 Gorilla gorilla 98.33 0.00e+00 1550.00
IUUC-Hsa-045974 Homo sapiens 98.85 0.00e+00 1558.00
IUUC-Itr-049009 Ictidomys tridecemlineatus 98.85 0.00e+00 1555.00
IUUC-Lch-050615 Latimeria chalumnae 99.08 0.00e+00 1516.00
IUUC-Loc-051807 Lepisosteus oculatus 98.59 0.00e+00 1552.00
IUUC-Laf-053601 Loxodonta africana 98.71 0.00e+00 1546.00
IUUC-Mcc-055260 Macaca mulatta 98.85 0.00e+00 1556.00
IUUC-Meu-056632 Macropus eugenii 99.58 0.00e+00 957.00
IUUC-Mga-059658 Meleagris gallopavo 98.97 0.00e+00 1545.00
IUUC-Mmr-061424 Microcebus murinus 88.83 0.00e+00 1345.00
IUUC-Mdo-061836 Monodelphis domestica 98.97 0.00e+00 1557.00
IUUC-Mmu-063757 Mus musculus 97.31 0.00e+00 1538.00
IUUC-Mpu-065823 Mustela putorius furo 98.85 0.00e+00 1557.00
IUUC-Mlu-066969 Myotis lucifugus 98.32 0.00e+00 1540.00
IUUC-Nle-069943 Nomascus leucogenys 98.85 0.00e+00 1558.00
IUUC-Opr-070820 Ochotona princeps 99.08 0.00e+00 863.00
IUUC-Ont-071599 Oreochromis niloticus 96.41 0.00e+00 1531.00
IUUC-Oan-072743 Ornithorhynchus anatinus 99.21 0.00e+00 1518.00
IUUC-Ocu-074586 Oryctolagus cuniculus 98.85 0.00e+00 1558.00
IUUC-Ola-087526 Oryzias latipes 96.41 0.00e+00 1531.00
IUUC-Oga-088425 Otolemur garnettii 94.20 0.00e+00 1505.00
IUUC-Oar-089785 Ovis aries 98.85 0.00e+00 1558.00
IUUC-Ptr-091242 Pan troglodytes 98.85 0.00e+00 1558.00
IUUC-Pan-092246 Papio anubis 98.85 0.00e+00 1558.00
IUUC-Psi-094081 Pelodiscus sinensis 99.22 0.00e+00 1550.00
IUUC-Pma-094735 Petromyzon marinus 82.49 0.00e+00 749.00
IUUC-Pfo-097305 Poecilia formosa 96.03 0.00e+00 1522.00
IUUC-Pab-098248 Pongo abelii 92.69 0.00e+00 1437.00
IUUC-Pca-100756 Procavia capensis 87.31 0.00e+00 867.00
IUUC-Pva-102990 Pteropus vampyrus 85.15 0.00e+00 913.00
IUUC-Rno-105887 Rattus norvegicus 97.56 0.00e+00 1540.00
IUUC-Sha-107016 Sarcophilus harrisii 98.97 0.00e+00 1557.00
IUUC-Sar-113558 Sorex araneus 93.01 0.00e+00 1472.00
IUUC-Ssc-115414 Sus scrofa 98.85 0.00e+00 1558.00
IUUC-Tgu-116801 Taeniopygia guttata 98.21 0.00e+00 1536.00
IUUC-Tru-117565 Takifugu rubripes 96.41 0.00e+00 1530.00
IUUC-Tsy-119292 Tarsius syrichta 92.79 0.00e+00 1361.00
IUUC-Tni-120471 Tetraodon nigroviridis 96.29 0.00e+00 1523.00
IUUC-Tbe-127838 Tupaia belangeri 93.08 0.00e+00 1489.00
IUUC-Ttr-128345 Tursiops truncatus 98.33 0.00e+00 1550.00
IUUC-Vpa-130191 Vicugna pacos 90.23 0.00e+00 850.00
Created Date 25-Jun-2017

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