iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020593

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03000896

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000004651.3	ENSCAFT00000007480.3	ENSCAFP00000006923.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.80e-06	28.1	351	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+ +  Cl +w     + s +++CP Cr
   Q: 351  CKICAEGNKD-VKIKPCGHLLCSRCLAAW-----QNSDSQTCPFCR 390
           99********.******************.....7899999****8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAAAAAPRRR RWEEARELRR AVRLLQRLEE QCGDPRLASG PPSLRDLLPR TAQLLRDVAH 60
ARQAAGGGGP EDPGGARDFL IVYVHNLEAK SRQVAALLPS RGDRGADDEL FREGSRLRRQ 120

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Nucleotide Sequence
(Fasta)

ATGGCCGCGG CGGCTGCACC CCGGAGGCGG CGGTGGGAAG AGGCCCGCGA GCTCCGCCGC 60
GCGGTGAGGC TGCTGCAGCG CCTGGAGGAG CAATGCGGGG ACCCCCGGCT GGCCTCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0045121--C:membrane raft
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006508--P:proteolysis

KEGG

cfa:612343

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	88.05	0.00e+00	750.00
IUUC-Bta-012705	Bos taurus	77.96	0.00e+00	675.00
IUUC-Cja-019179	Callithrix jacchus	78.74	0.00e+00	635.00
IUUC-Cpo-021289	Cavia porcellus	74.69	1.00e-162	566.00
IUUC-Csa-023966	Chlorocebus sabaeus	71.96	2.00e-174	605.00
IUUC-Dor-030246	Dipodomys ordii	78.32	1.00e-122	433.00
IUUC-Eca-033921	Equus caballus	74.15	3.00e-149	521.00
IUUC-Fca-035747	Felis catus	69.21	3.00e-172	598.00
IUUC-Ggo-044622	Gorilla gorilla	80.44	8.00e-151	526.00
IUUC-Hsa-045735	Homo sapiens	80.19	0.00e+00	649.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	74.76	3.00e-171	594.00
IUUC-Laf-053983	Loxodonta africana	73.58	0.00e+00	670.00
IUUC-Mmr-061310	Microcebus murinus	73.39	0.00e+00	639.00
IUUC-Mmu-064155	Mus musculus	68.87	0.00e+00	629.00
IUUC-Mpu-066655	Mustela putorius furo	82.70	0.00e+00	724.00
IUUC-Mlu-067929	Myotis lucifugus	82.89	4.00e-153	533.00
IUUC-Nle-070065	Nomascus leucogenys	66.43	4.00e-146	510.00
IUUC-Ocu-074049	Oryctolagus cuniculus	74.48	1.00e-125	442.00
IUUC-Oga-087952	Otolemur garnettii	79.90	0.00e+00	669.00
IUUC-Oar-089382	Ovis aries	75.68	0.00e+00	643.00
IUUC-Pan-092075	Papio anubis	78.74	7.00e-173	600.00
IUUC-Pab-098100	Pongo abelii	70.29	4.00e-157	547.00
IUUC-Pca-100830	Procavia capensis	80.33	2.00e-106	379.00
IUUC-Pva-102714	Pteropus vampyrus	77.65	5.00e-158	550.00
IUUC-Rno-105348	Rattus norvegicus	69.58	2.00e-180	625.00
IUUC-Sha-107138	Sarcophilus harrisii	60.30	3.00e-120	424.00
IUUC-Ssc-116424	Sus scrofa	78.31	0.00e+00	713.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence