iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053689

UUCD1 version

UUC-LoA-01098

Ensembl Protein ID

ENSLAFP00000027944.1

UniProt Accession

G3UJD6; G3UJD6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000015972.4	ENSLAFT00000032011.1	ENSLAFP00000027944.1
ENSLAFG00000015972.4	ENSLAFT00000015969.4	ENSLAFP00000013396.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.00e-81	272.4	490	995

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 490  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 567
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e+ + +++ l++         +   +   +k+li+++F+g+l+++i cl+c+++s++ e
   Q: 568  QDCSEYLRFLLDRLHEEEKIlkvQSSHKPSESLGCSETFLQEVaskaalltETPCTSDGEKTLIEKMFGGKLQTHICCLNCRSTSQKVE 656
           *****************95466666666666666666666666788888877777777888**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++++++                                                                       
   Q: 657  AFTDLSLAFCPSSSMEHLsfqepvsspnalndglmqasvsgpseepvvynpaaaafvcdsvvnertvdslphelrctentsvpnesski 745
           **********999887779********************************************************************** PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
                           s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl 
   Q: 746  lvnkdvsqkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLI 834
           ***************************************************************************************** PP
   S: 259  Ldlspfcts.....peekqke...............................kkkYeLiavvvHsG.slssGHYvayvkn......... 301
           L+l    t+     +     e                                + Y L +vvvHsG s++sGHY++y++n         
   Q: 835  LELPVKRTTtlsslS-----EswsidvdftdtrenlakklkpsgteeaccpkLVPYLLNSVVVHSGiSSESGHYYSYARNitgtdssyq 918
           999855555344450.....245555555555555556666666666777779************************************ PP
   S: 302  ....................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                                +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 919  mchhqsetlalaspqshllgkdsptaiieqnlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 995
           ************9999999999999999988865544555*******************999************986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

AGTGGGRACA AATGQSEGWV RAQPGAVCEW RRRRGTELGM SDDNGQDPRG LVSSSHPLPL 60
KRMIIRKVVE SAEHWLDEAQ CEAMFDLTTR LILEGQDPFQ RQVGHQVLEA YARYHRPEFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGGCACTG GAGGCGGCCG CGCCTGCGCG GCAGCGACGG GGCAAAGCGA GGGGTGGGTC 60
CGAGCGCAGC CGGGGGCAGT CTGCGAGTGG AGGCGGAGGA GGGGTACTGA GCTGGGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	92.70	0.00e+00	1840.00
IUUC-Apl-003435	Anas platyrhynchos	76.30	0.00e+00	1278.00
IUUC-Aca-004556	Anolis carolinensis	71.24	0.00e+00	1314.00
IUUC-Ame-010616	Astyanax mexicanus	61.28	0.00e+00	1217.00
IUUC-Bta-013544	Bos taurus	92.69	0.00e+00	1836.00
IUUC-Cja-018745	Callithrix jacchus	91.35	0.00e+00	1843.00
IUUC-Cfa-020434	Canis familiaris	88.64	0.00e+00	1760.00
IUUC-Cpo-021666	Cavia porcellus	90.95	0.00e+00	1762.00
IUUC-Csa-023965	Chlorocebus sabaeus	92.97	0.00e+00	1941.00
IUUC-Cho-024809	Choloepus hoffmanni	85.87	0.00e+00	1306.00
IUUC-Cin-025604	Ciona intestinalis	38.36	1.00e-40	160.00
IUUC-Csv-026333	Ciona savignyi	43.43	2.00e-30	125.00
IUUC-Dre-028338	Danio rerio	61.99	0.00e+00	1229.00
IUUC-Dno-029372	Dasypus novemcinctus	93.17	0.00e+00	1862.00
IUUC-Dor-030752	Dipodomys ordii	88.18	0.00e+00	1249.00
IUUC-Dme-031871	Drosophila melanogaster	30.96	3.00e-45	177.00
IUUC-Ete-032588	Echinops telfairi	82.86	0.00e+00	1202.00
IUUC-Eca-034416	Equus caballus	94.13	0.00e+00	1929.00
IUUC-Eeu-035132	Erinaceus europaeus	73.15	0.00e+00	1402.00
IUUC-Fca-036137	Felis catus	92.97	0.00e+00	1892.00
IUUC-Fal-037297	Ficedula albicollis	75.29	0.00e+00	1452.00
IUUC-Gmo-038727	Gadus morhua	65.40	0.00e+00	999.00
IUUC-Gga-041091	Gallus gallus	73.24	0.00e+00	1390.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.28	0.00e+00	1127.00
IUUC-Ggo-045376	Gorilla gorilla	88.47	0.00e+00	1773.00
IUUC-Hsa-046444	Homo sapiens	93.17	0.00e+00	1908.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	92.97	0.00e+00	1881.00
IUUC-Lch-050500	Latimeria chalumnae	71.74	0.00e+00	1418.00
IUUC-Loc-052625	Lepisosteus oculatus	64.17	0.00e+00	1288.00
IUUC-Mcc-055286	Macaca mulatta	92.88	0.00e+00	1884.00
IUUC-Mga-059905	Meleagris gallopavo	74.43	0.00e+00	1245.00
IUUC-Mmr-061397	Microcebus murinus	93.94	0.00e+00	1886.00
IUUC-Mdo-062833	Monodelphis domestica	86.95	0.00e+00	1803.00
IUUC-Mmu-063157	Mus musculus	89.32	0.00e+00	1815.00
IUUC-Mpu-066434	Mustela putorius furo	93.46	0.00e+00	1891.00
IUUC-Mlu-068178	Myotis lucifugus	91.55	0.00e+00	1795.00
IUUC-Nle-070153	Nomascus leucogenys	92.69	0.00e+00	1824.00
IUUC-Ont-072330	Oreochromis niloticus	63.31	0.00e+00	1230.00
IUUC-Oan-072709	Ornithorhynchus anatinus	81.22	0.00e+00	1315.00
IUUC-Ocu-074832	Oryctolagus cuniculus	93.46	0.00e+00	1870.00
IUUC-Ola-087003	Oryzias latipes	56.04	9.00e-50	189.00
IUUC-Oga-088517	Otolemur garnettii	88.96	0.00e+00	1786.00
IUUC-Oar-089472	Ovis aries	89.22	0.00e+00	1764.00
IUUC-Ptr-090996	Pan troglodytes	92.88	0.00e+00	1905.00
IUUC-Pan-091837	Papio anubis	91.09	0.00e+00	1872.00
IUUC-Psi-093236	Pelodiscus sinensis	76.89	0.00e+00	1191.00
IUUC-Pma-094349	Petromyzon marinus	52.70	0.00e+00	976.00
IUUC-Pfo-097193	Poecilia formosa	62.15	0.00e+00	1143.00
IUUC-Pab-098710	Pongo abelii	93.17	0.00e+00	1909.00
IUUC-Pca-100794	Procavia capensis	85.08	0.00e+00	1702.00
IUUC-Pva-102722	Pteropus vampyrus	92.02	0.00e+00	1853.00
IUUC-Rno-105743	Rattus norvegicus	89.12	0.00e+00	1785.00
IUUC-Sha-106563	Sarcophilus harrisii	85.99	0.00e+00	1471.00
IUUC-Sar-113533	Sorex araneus	76.71	0.00e+00	1533.00
IUUC-Ssc-116259	Sus scrofa	82.69	0.00e+00	1561.00
IUUC-Tgu-117475	Taeniopygia guttata	75.71	0.00e+00	1326.00
IUUC-Tru-118623	Takifugu rubripes	62.60	0.00e+00	1143.00
IUUC-Tsy-119250	Tarsius syrichta	91.04	0.00e+00	1484.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.45	0.00e+00	1060.00
IUUC-Tbe-127936	Tupaia belangeri	80.85	0.00e+00	1546.00
IUUC-Ttr-128483	Tursiops truncatus	80.46	0.00e+00	1417.00
IUUC-Vpa-130303	Vicugna pacos	97.55	0.00e+00	1059.00
IUUC-Xtr-132773	Xenopus tropicalis	71.39	0.00e+00	1395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence