iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069016

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01186669

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000005710.1	ENSNLET00000007258.1	ENSNLEP00000006915.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.30e-16	58.5	152	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ +SLqhLCRl+I++c+g      i++LPLP +LkdYL+++++q
   Q: 152  TKPLYTSAPSLQHLCRLTINKCTGA-----IWGLPLPTRLKDYLEEYKFQ 196
           678999*******************.....8***************9886 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MTLRCLEPSG NGEGTRIPWG TAGSAEEPSP EAARLAXXXX XTKTPGWYWG SMTVNEAKEK 60
LKEAPEGTFL IRDSSHSDYL LTISVKTSAG PTNLRIEYQD GKFRLDSIIC VKSKLKQFDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGC GGTGCCTCGA GCCCTCCGGG AATGGGATGA AGGTACGCGG ATTCCGTGGG 60
GGACCGCGGG GTCGGCGGAG GAGCCATCCC CGGAGGCGGC GCGTCTGGCN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	91.41	7.00e-97	345.00
IUUC-Apl-003484	Anas platyrhynchos	80.26	3.00e-72	263.00
IUUC-Aca-004253	Anolis carolinensis	69.51	3.00e-69	253.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	2.80e-02	32.70
IUUC-Ame-011267	Astyanax mexicanus	61.08	1.00e-56	212.00
IUUC-Bta-013183	Bos taurus	90.40	1.00e-94	338.00
IUUC-Bra-017915	Brassica rapa	33.90	4.90e-02	32.00
IUUC-Cja-018862	Callithrix jacchus	93.43	3.00e-98	350.00
IUUC-Cfa-020226	Canis familiaris	90.36	4.00e-92	330.00
IUUC-Cpo-022414	Cavia porcellus	91.41	2.00e-100	357.00
IUUC-Csa-023758	Chlorocebus sabaeus	92.93	4.00e-102	363.00
IUUC-Cho-024471	Choloepus hoffmanni	86.84	8.00e-72	262.00
IUUC-Dre-028288	Danio rerio	61.76	3.00e-60	224.00
IUUC-Dno-029565	Dasypus novemcinctus	92.04	3.00e-98	351.00
IUUC-Dor-030447	Dipodomys ordii	98.68	3.00e-87	313.00
IUUC-Ete-033023	Echinops telfairi	89.39	2.00e-102	364.00
IUUC-Fca-036469	Felis catus	91.92	7.00e-96	342.00
IUUC-Fal-036642	Ficedula albicollis	78.21	4.00e-71	260.00
IUUC-Gmo-039331	Gadus morhua	59.62	7.00e-33	132.00
IUUC-Gga-040809	Gallus gallus	78.06	6.00e-72	262.00
IUUC-Gac-041398	Gasterosteus aculeatus	57.74	9.00e-56	209.00
IUUC-Ggo-045341	Gorilla gorilla	93.94	2.00e-98	350.00
IUUC-Hsa-046557	Homo sapiens	93.43	7.00e-107	379.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	82.69	6.00e-94	336.00
IUUC-Lch-050160	Latimeria chalumnae	60.40	7.00e-48	182.00
IUUC-Loc-051825	Lepisosteus oculatus	61.54	3.00e-58	217.00
IUUC-Laf-053560	Loxodonta africana	90.91	6.00e-94	336.00
IUUC-Mcc-055890	Macaca mulatta	92.93	4.00e-97	346.00
IUUC-Meu-056218	Macropus eugenii	77.27	1.00e-89	321.00
IUUC-Mga-059755	Meleagris gallopavo	79.74	4.00e-72	263.00
IUUC-Mmr-061387	Microcebus murinus	91.92	3.00e-100	357.00
IUUC-Mdo-062383	Monodelphis domestica	78.28	1.00e-89	321.00
IUUC-Mmu-063443	Mus musculus	88.89	4.00e-97	346.00
IUUC-Mpu-066459	Mustela putorius furo	90.91	6.00e-95	339.00
IUUC-Mlu-068040	Myotis lucifugus	92.42	8.00e-99	352.00
IUUC-Opr-071087	Ochotona princeps	85.35	3.00e-96	343.00
IUUC-Ont-072340	Oreochromis niloticus	53.43	4.00e-58	217.00
IUUC-Oan-073443	Ornithorhynchus anatinus	76.14	4.00e-86	310.00
IUUC-Ocu-074539	Oryctolagus cuniculus	90.36	8.00e-95	339.00
IUUC-Ogu-078951	Oryza glumaepatula	27.03	5.50e-02	32.30
IUUC-Oin-079476	Oryza indica	27.03	4.40e-02	32.30
IUUC-Oni-082613	Oryza nivara	27.03	4.40e-02	32.30
IUUC-Oru-085265	Oryza rufipogon	27.03	4.60e-02	32.30
IUUC-Ola-087004	Oryzias latipes	60.13	4.00e-55	206.00
IUUC-Oga-088438	Otolemur garnettii	91.41	1.00e-100	358.00
IUUC-Oar-089932	Ovis aries	90.40	2.00e-94	337.00
IUUC-Ptr-091037	Pan troglodytes	93.94	2.00e-98	350.00
IUUC-Pan-092767	Papio anubis	92.93	2.00e-97	347.00
IUUC-Psi-093099	Pelodiscus sinensis	79.61	1.00e-72	265.00
IUUC-Pma-094671	Petromyzon marinus	48.37	4.00e-36	144.00
IUUC-Pfo-097073	Poecilia formosa	48.19	2.00e-52	198.00
IUUC-Pab-098319	Pongo abelii	93.43	1.00e-99	355.00
IUUC-Pca-101117	Procavia capensis	89.85	6.00e-98	349.00
IUUC-Pva-102117	Pteropus vampyrus	90.91	1.00e-93	335.00
IUUC-Rno-105913	Rattus norvegicus	88.38	1.00e-96	345.00
IUUC-Sha-106500	Sarcophilus harrisii	79.19	6.00e-89	319.00
IUUC-Ssc-115252	Sus scrofa	91.92	4.00e-101	359.00
IUUC-Tgu-117524	Taeniopygia guttata	76.77	4.00e-69	253.00
IUUC-Tsy-119335	Tarsius syrichta	95.36	3.00e-85	306.00
IUUC-Tni-120263	Tetraodon nigroviridis	59.39	3.00e-54	204.00
IUUC-Tca-121866	Theobroma cacao	42.86	1.20e-02	34.30
IUUC-Tbe-127915	Tupaia belangeri	89.90	2.00e-91	328.00
IUUC-Ttr-128372	Tursiops truncatus	91.92	7.00e-101	359.00
IUUC-Vpa-130422	Vicugna pacos	98.68	6.00e-87	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence