iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000008633.1	ENSCJAT00000016789.1	ENSCJAP00000015890.1
ENSCJAG00000008633.1	ENSCJAT00000016787.1	ENSCJAP00000015888.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.10e-08	34.6	12	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +      f+CP+Cr
   Q: 12   CPICCSLFDD-PRVLPCSHNFCKKCLEGIlegsVRNSLWRPAPFKCPTCR 60
           ********99.**************97776666666666999999****8 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

DVMELLEEDL TCPICCSLFD DPRVLPCSHN FCKKCLEGIL EGSVRNSLWR PAPFKCPTCR 60
KETSATGINS LQVNYSLKGI VEKYNKIKIS PKMPVCKVHL GQPLNIFCLT DMQLICGICA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTGCGGTG GTGCCGGGCG CGTACCGTGC GGTTCGTGCT GTTGGAGGAC AGGGGGTAGC 60
GCGGCCTCTC CCGCTCGCCG GAGGTCAGAG ATAAGTACCC GTTGCCCGGC TACTCTCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	93.64	0.00e+00	743.00
IUUC-Apl-004168	Anas platyrhynchos	75.74	0.00e+00	637.00
IUUC-Aca-004395	Anolis carolinensis	69.61	4.00e-167	580.00
IUUC-Ame-011325	Astyanax mexicanus	46.13	7.00e-68	250.00
IUUC-Bta-012613	Bos taurus	92.38	0.00e+00	732.00
IUUC-Cfa-021019	Canis familiaris	92.67	0.00e+00	736.00
IUUC-Cpo-021845	Cavia porcellus	91.89	0.00e+00	727.00
IUUC-Csa-023380	Chlorocebus sabaeus	96.31	0.00e+00	754.00
IUUC-Cho-024733	Choloepus hoffmanni	83.26	3.00e-91	328.00
IUUC-Dre-028675	Danio rerio	60.80	6.00e-111	394.00
IUUC-Dno-030018	Dasypus novemcinctus	90.44	0.00e+00	738.00
IUUC-Dor-030599	Dipodomys ordii	91.01	6.00e-132	462.00
IUUC-Dse-031522	Dothistroma septosporum	35.53	2.00e-06	46.20
IUUC-Ete-033134	Echinops telfairi	87.56	0.00e+00	723.00
IUUC-Eca-033931	Equus caballus	94.13	0.00e+00	737.00
IUUC-Eeu-034903	Erinaceus europaeus	90.95	0.00e+00	722.00
IUUC-Fca-035642	Felis catus	93.37	0.00e+00	735.00
IUUC-Fal-037108	Ficedula albicollis	75.98	0.00e+00	643.00
IUUC-Gga-040903	Gallus gallus	74.25	2.00e-180	625.00
IUUC-Ggo-044635	Gorilla gorilla	96.58	0.00e+00	759.00
IUUC-Hsa-046345	Homo sapiens	96.58	0.00e+00	759.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	91.22	0.00e+00	702.00
IUUC-Lch-050599	Latimeria chalumnae	61.39	9.00e-141	493.00
IUUC-Loc-052378	Lepisosteus oculatus	64.38	8.00e-119	419.00
IUUC-Laf-053332	Loxodonta africana	90.93	0.00e+00	724.00
IUUC-Mcc-054705	Macaca mulatta	95.60	0.00e+00	756.00
IUUC-Meu-056825	Macropus eugenii	83.41	0.00e+00	708.00
IUUC-Mga-059528	Meleagris gallopavo	74.75	0.00e+00	636.00
IUUC-Mmr-060688	Microcebus murinus	94.62	0.00e+00	741.00
IUUC-Mdo-061882	Monodelphis domestica	82.89	0.00e+00	712.00
IUUC-Mmu-064352	Mus musculus	88.21	0.00e+00	739.00
IUUC-Mpu-066712	Mustela putorius furo	92.61	0.00e+00	678.00
IUUC-Mlu-068093	Myotis lucifugus	91.65	0.00e+00	718.00
IUUC-Nle-069310	Nomascus leucogenys	96.56	0.00e+00	753.00
IUUC-Ont-071759	Oreochromis niloticus	59.28	2.00e-110	392.00
IUUC-Oan-073673	Ornithorhynchus anatinus	80.00	0.00e+00	690.00
IUUC-Ocu-074192	Oryctolagus cuniculus	92.18	0.00e+00	744.00
IUUC-Ola-087424	Oryzias latipes	58.77	7.00e-109	387.00
IUUC-Oga-088808	Otolemur garnettii	93.86	0.00e+00	742.00
IUUC-Oar-089553	Ovis aries	92.42	0.00e+00	735.00
IUUC-Ptr-090518	Pan troglodytes	96.33	0.00e+00	756.00
IUUC-Pan-092781	Papio anubis	95.35	0.00e+00	754.00
IUUC-Psi-093914	Pelodiscus sinensis	75.61	0.00e+00	634.00
IUUC-Pfo-096346	Poecilia formosa	52.42	3.00e-109	388.00
IUUC-Pca-100914	Procavia capensis	89.51	0.00e+00	739.00
IUUC-Pva-102728	Pteropus vampyrus	92.67	0.00e+00	733.00
IUUC-Rno-105922	Rattus norvegicus	87.71	0.00e+00	686.00
IUUC-Sha-107124	Sarcophilus harrisii	83.37	0.00e+00	718.00
IUUC-Sar-113607	Sorex araneus	88.51	0.00e+00	707.00
IUUC-Ssc-116355	Sus scrofa	93.61	0.00e+00	740.00
IUUC-Tgu-116476	Taeniopygia guttata	76.23	0.00e+00	642.00
IUUC-Tru-118737	Takifugu rubripes	60.26	9.00e-113	400.00
IUUC-Tsy-118908	Tarsius syrichta	93.89	0.00e+00	764.00
IUUC-Tbe-127258	Tupaia belangeri	95.35	0.00e+00	752.00
IUUC-Vpa-130138	Vicugna pacos	92.42	0.00e+00	741.00
IUUC-Xtr-132100	Xenopus tropicalis	59.76	2.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence