iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.90e-12	46.9	57	119

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv + v+g+ef+ah++vLaasS++F++   l+++ +        +   ++p++f+++l   Ytg+l++
   Q: 57   CDVSIRVQGREFRAHRAVLAASSPYFHDQVlLKGMTSI------SLPSvMDPGAFETVLASAYTGRLSM 119
           8***************************9845555544......3444578***************986 PP

Organism

Mus musculus

Functional Description
(View)

Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein Sequence
(Fasta)

MEPSALSPSG ATLPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ RLQGQLCDVS 60
IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM DPGAFETVLA SAYTGRLSMA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACGTCCAGA GCTCGGGGTG GAGCCTGGGA AGCGGAAGCC AGCACTGGTC AATGAGACAA 60
GGTAGGCTTG TCGGATTAAA GGGGAACGAA GGTTTCGGCC AAACCAATTC CTGAGTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR029833--ZBT22
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

mmu:81630

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001767	Ailuropoda melanoleuca	84.59	0.00e+00	763.00
IUUC-Apl-003846	Anas platyrhynchos	67.39	4.00e-63	233.00
IUUC-Aca-005194	Anolis carolinensis	54.68	4.00e-129	455.00
IUUC-Ame-011159	Astyanax mexicanus	41.62	3.00e-101	362.00
IUUC-Bta-013111	Bos taurus	86.00	0.00e+00	694.00
IUUC-Cja-019634	Callithrix jacchus	85.20	0.00e+00	686.00
IUUC-Cfa-020967	Canis familiaris	81.24	0.00e+00	761.00
IUUC-Cpo-021465	Cavia porcellus	79.58	0.00e+00	750.00
IUUC-Csa-023077	Chlorocebus sabaeus	84.73	0.00e+00	661.00
IUUC-Dre-028178	Danio rerio	41.36	2.00e-97	350.00
IUUC-Dor-030717	Dipodomys ordii	84.43	0.00e+00	750.00
IUUC-Ete-033181	Echinops telfairi	68.09	1.00e-154	540.00
IUUC-Eca-033663	Equus caballus	85.90	0.00e+00	761.00
IUUC-Gmo-038995	Gadus morhua	69.88	5.00e-25	109.00
IUUC-Ggo-045042	Gorilla gorilla	83.44	0.00e+00	736.00
IUUC-Hsa-046542	Homo sapiens	82.95	0.00e+00	712.00
IUUC-Itr-048252	Ictidomys tridecemlineatus	82.30	0.00e+00	764.00
IUUC-Lch-049688	Latimeria chalumnae	49.28	1.00e-135	476.00
IUUC-Laf-054437	Loxodonta africana	79.87	0.00e+00	664.00
IUUC-Mcc-054995	Macaca mulatta	85.22	0.00e+00	656.00
IUUC-Mmr-061368	Microcebus murinus	82.35	0.00e+00	667.00
IUUC-Mdo-062574	Monodelphis domestica	74.07	2.00e-86	312.00
IUUC-Mpu-066306	Mustela putorius furo	84.92	0.00e+00	773.00
IUUC-Mlu-067446	Myotis lucifugus	80.03	0.00e+00	735.00
IUUC-Opr-070675	Ochotona princeps	61.33	2.00e-58	220.00
IUUC-Ont-072206	Oreochromis niloticus	49.77	4.00e-51	196.00
IUUC-Ocu-074392	Oryctolagus cuniculus	81.86	0.00e+00	665.00
IUUC-Ola-086973	Oryzias latipes	70.18	2.00e-44	173.00
IUUC-Oga-089041	Otolemur garnettii	82.03	2.00e-84	306.00
IUUC-Oar-090241	Ovis aries	85.36	0.00e+00	699.00
IUUC-Ptr-091294	Pan troglodytes	84.59	0.00e+00	704.00
IUUC-Pan-091696	Papio anubis	74.36	6.00e-77	281.00
IUUC-Psi-093312	Pelodiscus sinensis	54.19	7.00e-132	463.00
IUUC-Pfo-096385	Poecilia formosa	45.71	6.00e-49	189.00
IUUC-Pab-098065	Pongo abelii	84.56	0.00e+00	687.00
IUUC-Pca-100919	Procavia capensis	86.53	4.00e-81	296.00
IUUC-Pva-103075	Pteropus vampyrus	83.89	0.00e+00	710.00
IUUC-Rno-105534	Rattus norvegicus	94.74	0.00e+00	847.00
IUUC-Sha-106657	Sarcophilus harrisii	72.80	0.00e+00	627.00
IUUC-Ssc-115946	Sus scrofa	85.29	0.00e+00	692.00
IUUC-Tgu-116464	Taeniopygia guttata	76.32	4.00e-48	182.00
IUUC-Tru-118446	Takifugu rubripes	69.75	1.00e-46	181.00
IUUC-Tni-120333	Tetraodon nigroviridis	42.08	4.00e-93	335.00
IUUC-Ttr-129203	Tursiops truncatus	84.41	9.00e-134	470.00
IUUC-Xtr-131973	Xenopus tropicalis	50.47	5.00e-121	427.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence