iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091885

Ensembl Protein ID

ENSPANP00000018111.1

UniProt Accession

A0A096NYE8; A0A096NYE8_PAPAN

Genbank Protein ID

ENSPANP00000018111

Protein Name

Coronin

Genbank Nucleotide ID

AHZZ01037761

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000018235.1	ENSPANT00000026101.1	ENSPANP00000018111.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-16	58.4	61	93

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 61   GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 93
           8***********977799*************86 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

VKNDQCYDDI RVSRVTWDSS FCAVNPRFVA IIIEASGGGA FLVLPLHKTG RIDKSYPTVC 60
GHTGPVLDID WCPHNDQVIA SGSEDCTVMV WQIPENGLTL SLTEPVVILE GHSKRVGIVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAAAATG ACCAGTGCTA TGATGACATC CGGGTTTCTC GTGTGACCTG GGATAGTTCC 60
TTTTGTGCTG TCAATCCCAG ATTTGTTGCC ATAATCATAG AGGCAAGTGG GGGAGGAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010762--P:regulation of fibroblast migration
GO:1900027--P:regulation of ruffle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002236	Ailuropoda melanoleuca	99.13	0.00e+00	942.00
IUUC-Apl-003861	Anas platyrhynchos	94.09	0.00e+00	904.00
IUUC-Ang-009523	Aspergillus niger	41.34	6.00e-89	321.00
IUUC-Ame-011256	Astyanax mexicanus	80.09	0.00e+00	751.00
IUUC-Bta-013225	Bos taurus	98.25	0.00e+00	932.00
IUUC-Cja-019948	Callithrix jacchus	99.78	0.00e+00	955.00
IUUC-Cfa-020591	Canis familiaris	99.13	0.00e+00	942.00
IUUC-Cpo-021480	Cavia porcellus	98.91	0.00e+00	942.00
IUUC-Csa-024152	Chlorocebus sabaeus	99.78	0.00e+00	948.00
IUUC-Cho-024687	Choloepus hoffmanni	98.33	0.00e+00	863.00
IUUC-Dre-028541	Danio rerio	82.97	0.00e+00	754.00
IUUC-Dno-029552	Dasypus novemcinctus	98.81	0.00e+00	865.00
IUUC-Ete-032839	Echinops telfairi	89.74	0.00e+00	843.00
IUUC-Eca-034118	Equus caballus	98.25	0.00e+00	938.00
IUUC-Fca-035549	Felis catus	98.91	0.00e+00	942.00
IUUC-Fal-037065	Ficedula albicollis	93.87	0.00e+00	908.00
IUUC-Gmo-038678	Gadus morhua	76.81	0.00e+00	741.00
IUUC-Gga-040842	Gallus gallus	94.31	0.00e+00	911.00
IUUC-Gac-041543	Gasterosteus aculeatus	77.66	0.00e+00	736.00
IUUC-Ggo-044477	Gorilla gorilla	99.56	0.00e+00	946.00
IUUC-Hsa-046610	Homo sapiens	99.56	0.00e+00	946.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	98.91	0.00e+00	939.00
IUUC-Lch-050453	Latimeria chalumnae	82.66	0.00e+00	795.00
IUUC-Loc-052911	Lepisosteus oculatus	84.25	0.00e+00	799.00
IUUC-Laf-053416	Loxodonta africana	98.47	0.00e+00	940.00
IUUC-Mcc-055113	Macaca mulatta	99.56	0.00e+00	945.00
IUUC-Meu-056732	Macropus eugenii	81.26	0.00e+00	716.00
IUUC-Mga-060143	Meleagris gallopavo	94.31	0.00e+00	908.00
IUUC-Mmr-061130	Microcebus murinus	99.13	0.00e+00	943.00
IUUC-Mdo-062851	Monodelphis domestica	86.46	0.00e+00	771.00
IUUC-Mmu-063663	Mus musculus	97.16	0.00e+00	925.00
IUUC-Mpu-066179	Mustela putorius furo	98.91	0.00e+00	941.00
IUUC-Mlu-068175	Myotis lucifugus	98.91	0.00e+00	940.00
IUUC-Opr-070617	Ochotona princeps	97.60	0.00e+00	899.00
IUUC-Ont-072629	Oreochromis niloticus	82.49	0.00e+00	800.00
IUUC-Oan-073547	Ornithorhynchus anatinus	95.39	0.00e+00	913.00
IUUC-Ocu-074569	Oryctolagus cuniculus	96.94	0.00e+00	930.00
IUUC-Ola-086558	Oryzias latipes	79.83	0.00e+00	789.00
IUUC-Oga-089145	Otolemur garnettii	99.13	0.00e+00	943.00
IUUC-Oar-089654	Ovis aries	97.82	0.00e+00	933.00
IUUC-Ptr-090763	Pan troglodytes	99.78	0.00e+00	947.00
IUUC-Psi-093011	Pelodiscus sinensis	93.65	0.00e+00	902.00
IUUC-Pfo-097309	Poecilia formosa	82.06	0.00e+00	806.00
IUUC-Pab-097542	Pongo abelii	90.83	0.00e+00	840.00
IUUC-Pca-100630	Procavia capensis	84.62	0.00e+00	782.00
IUUC-Rno-105330	Rattus norvegicus	98.03	0.00e+00	933.00
IUUC-Sha-106695	Sarcophilus harrisii	94.40	0.00e+00	770.00
IUUC-Ssc-115348	Sus scrofa	98.25	0.00e+00	936.00
IUUC-Tgu-116597	Taeniopygia guttata	94.09	0.00e+00	904.00
IUUC-Tru-118425	Takifugu rubripes	80.53	0.00e+00	784.00
IUUC-Tsy-119223	Tarsius syrichta	88.49	0.00e+00	734.00
IUUC-Tni-120610	Tetraodon nigroviridis	80.09	0.00e+00	781.00
IUUC-Tbe-127679	Tupaia belangeri	87.28	7.00e-174	603.00
IUUC-Ttr-129226	Tursiops truncatus	88.42	0.00e+00	805.00
IUUC-Vpa-130339	Vicugna pacos	99.37	0.00e+00	667.00
IUUC-Xtr-132873	Xenopus tropicalis	74.07	0.00e+00	711.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence