iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073739

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01243561

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000015583.2	ENSOANT00000024549.1	ENSOANP00000024545.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-13	51.1	293	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
            C+vC++gge    l++C+ C ++fH +Cl ++  +e p+s +w C +C 
   Q: 293  ECAVCRDGGE----LICCDGCPRAFHLTCLVPP-LTEIPSSGTWRCVRCV 337
           6*********....*******************.***************7 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

RPSGEGDVRQ LLKLYRTEIA MAVNDVFPLL HGLADHDVIT EDKFKETLSL KEKEGCHKAF 60
HALLTWLLSR DSSSIQDFWR ILFKDYNLER YARLQPIHNS FPKDIDLSRH RKGRKVPISL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCCTTCCG GAGAGGGGGA CGTGCGTCAG CTGTTGAAGC TGTACCGAAC GGAGATCGCT 60
ATGGCCGTCA ATGACGTTTT TCCACTGCTC CACGGACTGG CTGATCACGA TGTCATCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR011029--DEATH-like_dom
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0006955--P:immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	50.35	1.00e-131	462.00
IUUC-Aca-004543	Anolis carolinensis	77.42	3.00e-28	115.00
IUUC-Bta-012988	Bos taurus	59.35	1.00e-118	419.00
IUUC-Bdi-014663	Brachypodium distachyon	47.76	5.00e-12	67.00
IUUC-Cja-019486	Callithrix jacchus	43.95	4.00e-64	237.00
IUUC-Cfa-021069	Canis familiaris	51.43	2.00e-126	445.00
IUUC-Cpo-021649	Cavia porcellus	53.49	8.00e-115	406.00
IUUC-Csa-023960	Chlorocebus sabaeus	55.56	7.00e-125	440.00
IUUC-Cne-026966	Cryptococcus neoformans	52.94	5.00e-12	65.10
IUUC-Dre-028583	Danio rerio	44.57	7.00e-68	250.00
IUUC-Dno-029869	Dasypus novemcinctus	47.07	1.00e-79	290.00
IUUC-Dor-030263	Dipodomys ordii	65.93	8.00e-36	143.00
IUUC-Ete-032778	Echinops telfairi	72.90	1.00e-45	176.00
IUUC-Eca-034328	Equus caballus	51.44	3.00e-134	471.00
IUUC-Fca-035400	Felis catus	58.69	3.00e-126	444.00
IUUC-Fal-036644	Ficedula albicollis	51.75	2.00e-87	315.00
IUUC-Fso-038262	Fusarium solani	40.82	1.00e-08	55.50
IUUC-Ggo-045250	Gorilla gorilla	54.63	4.00e-127	447.00
IUUC-Hsa-046603	Homo sapiens	54.25	1.00e-130	459.00
IUUC-Hvu-047073	Hordeum vulgare	59.57	1.00e-12	68.60
IUUC-Itr-048977	Ictidomys tridecemlineatus	51.62	5.00e-124	437.00
IUUC-Lch-050310	Latimeria chalumnae	45.92	6.00e-115	407.00
IUUC-Loc-052508	Lepisosteus oculatus	53.16	3.00e-95	341.00
IUUC-Laf-054028	Loxodonta africana	59.03	2.00e-104	372.00
IUUC-Mcc-054935	Macaca mulatta	54.99	6.00e-134	470.00
IUUC-Mga-059318	Meleagris gallopavo	43.38	6.00e-65	240.00
IUUC-Mmr-061557	Microcebus murinus	45.60	4.00e-96	344.00
IUUC-Mdo-062475	Monodelphis domestica	63.14	2.00e-174	605.00
IUUC-Mmu-063994	Mus musculus	51.81	2.00e-136	478.00
IUUC-Mpu-066347	Mustela putorius furo	51.23	5.00e-143	500.00
IUUC-Mlu-068239	Myotis lucifugus	45.41	2.00e-61	229.00
IUUC-Nle-069544	Nomascus leucogenys	69.23	3.00e-22	97.80
IUUC-Opr-071199	Ochotona princeps	55.64	3.00e-59	222.00
IUUC-Ont-072571	Oreochromis niloticus	35.24	1.00e-40	160.00
IUUC-Ogl-077865	Oryza glaberrima	57.45	2.00e-12	67.40
IUUC-Olo-080499	Oryza longistaminata	57.45	2.00e-12	68.20
IUUC-Opu-083209	Oryza punctata	57.45	3.00e-12	67.80
IUUC-Ola-086528	Oryzias latipes	37.92	3.00e-47	182.00
IUUC-Oga-088353	Otolemur garnettii	53.53	1.00e-132	466.00
IUUC-Oar-090065	Ovis aries	59.48	6.00e-118	416.00
IUUC-Ptr-091347	Pan troglodytes	54.44	3.00e-123	434.00
IUUC-Pan-092423	Papio anubis	54.17	1.00e-128	452.00
IUUC-Psi-093798	Pelodiscus sinensis	61.27	4.00e-168	583.00
IUUC-Pfo-096145	Poecilia formosa	34.71	2.00e-41	163.00
IUUC-Pab-098369	Pongo abelii	64.44	7.00e-99	353.00
IUUC-Pca-100537	Procavia capensis	49.26	9.00e-122	429.00
IUUC-Pva-102639	Pteropus vampyrus	53.54	8.00e-121	426.00
IUUC-Rno-105285	Rattus norvegicus	53.75	4.00e-139	487.00
IUUC-Sha-107159	Sarcophilus harrisii	57.92	1.00e-163	569.00
IUUC-Ssc-115773	Sus scrofa	50.17	6.00e-131	460.00
IUUC-Tgu-116922	Taeniopygia guttata	49.85	5.00e-84	303.00
IUUC-Tru-118263	Takifugu rubripes	35.95	1.00e-60	226.00
IUUC-Tsy-119270	Tarsius syrichta	52.63	5.00e-62	231.00
IUUC-Tni-120138	Tetraodon nigroviridis	35.14	5.00e-65	241.00
IUUC-Tca-121757	Theobroma cacao	45.76	1.00e-11	65.90
IUUC-Tae-124715	Triticum aestivum	59.57	1.00e-12	68.90
IUUC-Tbe-128077	Tupaia belangeri	49.81	1.00e-122	432.00
IUUC-Ttr-128781	Tursiops truncatus	63.89	1.00e-58	219.00
IUUC-Xtr-132665	Xenopus tropicalis	29.34	2.00e-18	85.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence