iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097876

Ensembl Protein ID

ENSPPYP00000024295.1

UniProt Accession

K7EUR8; K7EUR8_PONAB

Genbank Protein ID

ENSPPYP00000024295

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01166454

Gene Name

CRKL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000029862.1	ENSPPYT00000033557.1	ENSPPYP00000024295.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-12	47.4	124	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++e+v++lyd+ +++ ++L +kkG+++ +i  e+ +e W+++ ++  g+ G++P  +vekl
   Q: 124  NLEYVRTLYDFPGNDAEDLPFKKGEILVII--EKPEEQWWSA-RNKDGRVGMIPVPYVEKL 181
           5789**************************..88999***99.6**************997 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSSARFDSSD RSAWYMGPVS RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH 60
YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRYPSPPM GSVSAPNLPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCGCGCT GAGCGGAGGG GGGAGGTGGC TGCCGCTTCT CCCGCGTCCG CCATTTTGTT 60
GCTGTGGCTA TTGGGAACAA GCTGGGCAAA AGCACCCCGG AGGCGCGACG CTCCTTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0003723--F:RNA binding
GO:0009887--P:animal organ morphogenesis
GO:0009952--P:anterior/posterior pattern specification
GO:0001568--P:blood vessel development
GO:0007507--P:heart development
GO:0060017--P:parathyroid gland development
GO:0008284--P:positive regulation of cell proliferation
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0048538--P:thymus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002025	Ailuropoda melanoleuca	97.42	5.00e-136	476.00
IUUC-Apl-004166	Anas platyrhynchos	86.12	3.00e-121	427.00
IUUC-Aca-004695	Anolis carolinensis	63.74	4.00e-59	221.00
IUUC-Ame-011285	Astyanax mexicanus	77.20	5.00e-105	374.00
IUUC-Bta-013076	Bos taurus	71.55	6.00e-77	280.00
IUUC-Cja-019850	Callithrix jacchus	98.71	4.00e-137	480.00
IUUC-Cfa-020428	Canis familiaris	96.57	1.00e-134	472.00
IUUC-Cpo-022079	Cavia porcellus	95.71	8.00e-134	469.00
IUUC-Csa-023877	Chlorocebus sabaeus	99.14	5.00e-138	483.00
IUUC-Cin-025128	Ciona intestinalis	53.98	3.00e-60	225.00
IUUC-Csv-026340	Ciona savignyi	50.59	3.00e-54	204.00
IUUC-Dre-027833	Danio rerio	77.73	2.00e-100	358.00
IUUC-Dno-029510	Dasypus novemcinctus	93.99	2.00e-132	464.00
IUUC-Dor-030297	Dipodomys ordii	96.34	9.00e-140	489.00
IUUC-Dme-031600	Drosophila melanogaster	47.49	1.00e-46	179.00
IUUC-Eca-033810	Equus caballus	97.42	1.00e-135	475.00
IUUC-Fca-036412	Felis catus	97.42	5.00e-136	476.00
IUUC-Fal-037170	Ficedula albicollis	88.84	7.00e-117	413.00
IUUC-Gga-040733	Gallus gallus	89.27	3.00e-105	374.00
IUUC-Gac-042398	Gasterosteus aculeatus	80.00	3.00e-113	401.00
IUUC-Ggo-044447	Gorilla gorilla	99.30	1.00e-80	291.00
IUUC-Hsa-046989	Homo sapiens	99.57	3.00e-138	484.00
IUUC-Itr-048092	Ictidomys tridecemlineatus	97.42	1.00e-135	475.00
IUUC-Kpa-049154	Komagataella pastoris	40.91	1.00e-10	60.50
IUUC-Lch-050385	Latimeria chalumnae	56.07	3.00e-71	261.00
IUUC-Loc-052916	Lepisosteus oculatus	82.66	1.00e-113	402.00
IUUC-Laf-053545	Loxodonta africana	95.80	3.00e-78	283.00
IUUC-Mga-059586	Meleagris gallopavo	90.99	1.00e-118	419.00
IUUC-Mvi-060518	Microbotryum violaceum	37.70	4.00e-11	62.00
IUUC-Mdo-061868	Monodelphis domestica	87.98	4.00e-124	437.00
IUUC-Mmu-063179	Mus musculus	95.71	3.00e-134	471.00
IUUC-Mpu-065863	Mustela putorius furo	97.42	5.00e-136	476.00
IUUC-Mlu-067290	Myotis lucifugus	95.71	8.00e-134	469.00
IUUC-Nle-069118	Nomascus leucogenys	99.57	3.00e-138	484.00
IUUC-Opr-070565	Ochotona princeps	94.31	3.00e-137	480.00
IUUC-Ont-071608	Oreochromis niloticus	79.30	3.00e-114	404.00
IUUC-Oan-072801	Ornithorhynchus anatinus	88.21	6.00e-129	453.00
IUUC-Ocu-073759	Oryctolagus cuniculus	96.57	8.00e-135	473.00
IUUC-Ola-086748	Oryzias latipes	74.09	4.00e-94	337.00
IUUC-Oga-088248	Otolemur garnettii	97.00	6.00e-135	473.00
IUUC-Oar-089525	Ovis aries	71.19	7.00e-87	313.00
IUUC-Ptr-091553	Pan troglodytes	99.57	3.00e-138	484.00
IUUC-Pan-092639	Papio anubis	99.57	3.00e-138	484.00
IUUC-Psi-093546	Pelodiscus sinensis	84.95	3.00e-92	330.00
IUUC-Pma-094340	Petromyzon marinus	57.03	2.00e-77	282.00
IUUC-Pfo-096231	Poecilia formosa	79.92	1.00e-114	405.00
IUUC-Pca-100447	Procavia capensis	97.42	4.00e-136	477.00
IUUC-Pva-102346	Pteropus vampyrus	96.55	1.00e-133	468.00
IUUC-Rno-106017	Rattus norvegicus	95.71	6.00e-134	469.00
IUUC-Sha-106511	Sarcophilus harrisii	85.40	3.00e-67	247.00
IUUC-Sar-113583	Sorex araneus	95.71	3.00e-133	467.00
IUUC-Sre-115190	Sporisorium reilianum	30.00	2.00e-09	58.50
IUUC-Ssc-115339	Sus scrofa	94.42	1.00e-131	462.00
IUUC-Tgu-116454	Taeniopygia guttata	86.40	2.00e-61	228.00
IUUC-Tru-118580	Takifugu rubripes	74.80	1.00e-104	372.00
IUUC-Tsy-119327	Tarsius syrichta	96.14	7.00e-134	469.00
IUUC-Tni-120626	Tetraodon nigroviridis	75.29	1.00e-106	379.00
IUUC-Ttr-128248	Tursiops truncatus	96.14	1.00e-134	472.00
IUUC-Xtr-132626	Xenopus tropicalis	83.33	2.00e-116	411.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence