iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054266

Ensembl Protein ID

ENSLAFP00000013184.2

UniProt Accession

G3TFQ5; G3TFQ5_LOXAF

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

MARK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000015714.2	ENSLAFT00000015718.2	ENSLAFP00000013184.2
ENSLAFG00000015714.2	ENSLAFT00000030730.1	ENSLAFP00000028113.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	94.93	0.00e+00	1437.00	IUUC-Hsa-046631

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

IATVNERDTE NNMSVDGYTE PLIQPTKSSS RQNIPRCRNS ITSAADDQPH IGNYRLQKTI 60
GKGNFAKVKL ARHVLTGREV AVKIIDKTQL NPTSLQKLFR EVRIMKILNH PNIVKLFEVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCAACGG TGAACGAGCG GGACACGGAG AATGTGAGTA ACCGGAGCCT CCCGGGAGCG 60
GCCGGCCGAA GCCCTCCGCC GACCCCCGCT TCGCCTCGGC CCGGCCGCTC CCCGCCCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR033627--MARK1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030010--P:establishment of cell polarity
GO:0000226--P:microtubule cytoskeleton organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001559	Ailuropoda melanoleuca	95.37	0.00e+00	1413.00
IUUC-Ame-011737	Astyanax mexicanus	70.25	0.00e+00	1006.00
IUUC-Bta-013462	Bos taurus	95.88	0.00e+00	1387.00
IUUC-Cja-019358	Callithrix jacchus	94.04	0.00e+00	1458.00
IUUC-Cfa-020498	Canis familiaris	94.80	0.00e+00	1363.00
IUUC-Cpo-022467	Cavia porcellus	91.73	0.00e+00	1390.00
IUUC-Csa-023035	Chlorocebus sabaeus	94.68	0.00e+00	1472.00
IUUC-Dor-031094	Dipodomys ordii	86.64	0.00e+00	1229.00
IUUC-Ete-032429	Echinops telfairi	83.52	0.00e+00	1200.00
IUUC-Eca-033265	Equus caballus	95.36	0.00e+00	1352.00
IUUC-Eeu-034949	Erinaceus europaeus	73.71	0.00e+00	704.00
IUUC-Fca-035360	Felis catus	90.36	0.00e+00	1310.00
IUUC-Fal-036617	Ficedula albicollis	89.93	0.00e+00	1182.00
IUUC-Gac-041559	Gasterosteus aculeatus	77.41	0.00e+00	1110.00
IUUC-Hsa-046631	Homo sapiens	94.93	0.00e+00	1479.00
IUUC-Loc-051934	Lepisosteus oculatus	61.96	0.00e+00	831.00
IUUC-Mcc-054650	Macaca mulatta	94.80	0.00e+00	1470.00
IUUC-Meu-056525	Macropus eugenii	67.65	0.00e+00	972.00
IUUC-Mdo-061932	Monodelphis domestica	87.87	0.00e+00	1305.00
IUUC-Mmu-064104	Mus musculus	92.02	0.00e+00	1364.00
IUUC-Mpu-065989	Mustela putorius furo	94.45	0.00e+00	1152.00
IUUC-Mlu-067700	Myotis lucifugus	94.01	0.00e+00	1315.00
IUUC-Nle-069385	Nomascus leucogenys	93.54	0.00e+00	1451.00
IUUC-Opr-070302	Ochotona princeps	65.56	0.00e+00	971.00
IUUC-Ont-071262	Oreochromis niloticus	78.16	0.00e+00	1138.00
IUUC-Oan-073352	Ornithorhynchus anatinus	90.49	0.00e+00	1352.00
IUUC-Ocu-073777	Oryctolagus cuniculus	95.31	0.00e+00	1410.00
IUUC-Oar-089313	Ovis aries	92.32	0.00e+00	1355.00
IUUC-Ptr-091421	Pan troglodytes	95.06	0.00e+00	1480.00
IUUC-Psi-093307	Pelodiscus sinensis	90.46	0.00e+00	1314.00
IUUC-Pma-094666	Petromyzon marinus	65.79	0.00e+00	1010.00
IUUC-Pab-098232	Pongo abelii	95.06	0.00e+00	1480.00
IUUC-Pca-100975	Procavia capensis	83.18	0.00e+00	827.00
IUUC-Pva-102596	Pteropus vampyrus	88.49	0.00e+00	1351.00
IUUC-Rno-105027	Rattus norvegicus	91.63	0.00e+00	1360.00
IUUC-Sha-106668	Sarcophilus harrisii	90.24	0.00e+00	1305.00
IUUC-Ssc-115321	Sus scrofa	70.96	0.00e+00	974.00
IUUC-Tgu-116652	Taeniopygia guttata	89.73	0.00e+00	1369.00
IUUC-Tsy-119138	Tarsius syrichta	82.34	0.00e+00	906.00
IUUC-Tni-120412	Tetraodon nigroviridis	77.20	0.00e+00	1120.00
IUUC-Tbe-127841	Tupaia belangeri	95.23	0.00e+00	1191.00
IUUC-Ttr-128406	Tursiops truncatus	94.88	0.00e+00	1410.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence