iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-15	57.1	92	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgti 25
           gH + +++ +f   +d + +vs+s+Dg+i
   Q: 92   GHRANIFSAKFlpcTDdKQIVSCSGDGVI 120
           8************9666**********98 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSRSGSCPHL LWDVRKRSLG LEDPSRLRSR YLGRREFIQR LKLEATLNVH DGCVNTICWN 60
DTGEYILSGS DDTKLVISNP YSRKVLTTIR SGHRANIFSA KFLPCTDDKQ IVSCSGDGVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCGGCCTG TCCCCTCCCT CTCTTCCCCT CCCCACCCCC CGCGGTGGTC TCCCCTTTCC 60
ACCCCAGCCC CAGCAGAGCC ATGTCTCGGA GTGGCTCCTG CCCGCACCTG TTGTGGGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50096--IQ
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0005634--C:nucleus
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001399	Ailuropoda melanoleuca	88.03	0.00e+00	1483.00
IUUC-Apl-003181	Anas platyrhynchos	89.20	0.00e+00	707.00
IUUC-Aca-004953	Anolis carolinensis	69.16	0.00e+00	1139.00
IUUC-Acl-008211	Aspergillus clavatus	26.89	3.00e-26	114.00
IUUC-Afu-008828	Aspergillus fumigatus	27.30	3.00e-27	117.00
IUUC-Ate-010555	Aspergillus terreus	25.98	2.00e-25	111.00
IUUC-Ame-011314	Astyanax mexicanus	85.47	0.00e+00	664.00
IUUC-Bta-013552	Bos taurus	81.35	0.00e+00	1395.00
IUUC-Cja-019015	Callithrix jacchus	87.82	0.00e+00	1514.00
IUUC-Cfa-021249	Canis familiaris	88.34	0.00e+00	1477.00
IUUC-Cpo-021903	Cavia porcellus	91.33	0.00e+00	976.00
IUUC-Csa-023744	Chlorocebus sabaeus	86.03	0.00e+00	1478.00
IUUC-Cho-024527	Choloepus hoffmanni	72.62	0.00e+00	1103.00
IUUC-Dre-028040	Danio rerio	85.36	0.00e+00	663.00
IUUC-Dno-029777	Dasypus novemcinctus	87.74	0.00e+00	1467.00
IUUC-Dor-030879	Dipodomys ordii	75.00	0.00e+00	1226.00
IUUC-Ete-032607	Echinops telfairi	69.70	0.00e+00	949.00
IUUC-Eca-033396	Equus caballus	91.82	0.00e+00	741.00
IUUC-Eeu-034944	Erinaceus europaeus	60.52	0.00e+00	627.00
IUUC-Fca-036020	Felis catus	83.93	0.00e+00	1374.00
IUUC-Fal-037527	Ficedula albicollis	90.59	0.00e+00	730.00
IUUC-Gmo-039347	Gadus morhua	82.68	0.00e+00	636.00
IUUC-Gga-040564	Gallus gallus	91.04	0.00e+00	736.00
IUUC-Gac-042029	Gasterosteus aculeatus	83.70	0.00e+00	647.00
IUUC-Ggo-045634	Gorilla gorilla	81.61	1.00e-170	593.00
IUUC-Hsa-045743	Homo sapiens	92.83	0.00e+00	829.00
IUUC-Itr-048064	Ictidomys tridecemlineatus	93.69	0.00e+00	769.00
IUUC-Lch-050457	Latimeria chalumnae	71.88	0.00e+00	1189.00
IUUC-Loc-052880	Lepisosteus oculatus	87.22	0.00e+00	664.00
IUUC-Lma-053032	Leptosphaeria maculans	29.45	8.00e-27	116.00
IUUC-Laf-053836	Loxodonta africana	91.52	0.00e+00	801.00
IUUC-Mcc-055749	Macaca mulatta	86.86	0.00e+00	1506.00
IUUC-Mga-059293	Meleagris gallopavo	86.02	0.00e+00	632.00
IUUC-Mmr-060923	Microcebus murinus	88.35	0.00e+00	1495.00
IUUC-Mdo-063056	Monodelphis domestica	73.58	0.00e+00	1228.00
IUUC-Mmu-063121	Mus musculus	96.95	0.00e+00	892.00
IUUC-Mpu-066035	Mustela putorius furo	84.78	0.00e+00	1328.00
IUUC-Mlu-067903	Myotis lucifugus	89.04	0.00e+00	785.00
IUUC-Nfi-068606	Neosartorya fischeri	27.20	9.00e-27	115.00
IUUC-Nle-069415	Nomascus leucogenys	86.52	0.00e+00	1425.00
IUUC-Opr-070809	Ochotona princeps	67.86	6.00e-133	468.00
IUUC-Ont-071470	Oreochromis niloticus	84.46	0.00e+00	645.00
IUUC-Oan-072748	Ornithorhynchus anatinus	94.63	3.00e-130	457.00
IUUC-Ocu-073865	Oryctolagus cuniculus	89.74	0.00e+00	761.00
IUUC-Ola-086755	Oryzias latipes	83.33	0.00e+00	640.00
IUUC-Oga-088309	Otolemur garnettii	82.23	0.00e+00	1397.00
IUUC-Oar-090264	Ovis aries	89.17	0.00e+00	1481.00
IUUC-Ptr-090603	Pan troglodytes	86.97	0.00e+00	1498.00
IUUC-Pan-092480	Papio anubis	92.61	0.00e+00	832.00
IUUC-Psi-092973	Pelodiscus sinensis	71.46	2.00e-134	473.00
IUUC-Pfo-096506	Poecilia formosa	83.90	0.00e+00	641.00
IUUC-Pab-097581	Pongo abelii	74.89	0.00e+00	1226.00
IUUC-Pca-100155	Procavia capensis	70.48	0.00e+00	1179.00
IUUC-Pva-103022	Pteropus vampyrus	83.68	0.00e+00	1325.00
IUUC-Pte-104187	Pyrenophora teres	29.53	6.00e-28	120.00
IUUC-Pyt-104546	Pyrenophora triticirepentis	29.53	1.00e-26	115.00
IUUC-Sha-106790	Sarcophilus harrisii	82.06	0.00e+00	758.00
IUUC-Sja-107779	Schizosaccharomyces japonicus	32.27	7.00e-35	142.00
IUUC-Spo-108129	Schizosaccharomyces pombe	31.19	9.00e-33	135.00
IUUC-Ssc-115801	Sus scrofa	73.55	4.00e-106	377.00
IUUC-Tgu-116760	Taeniopygia guttata	89.15	0.00e+00	675.00
IUUC-Tru-118422	Takifugu rubripes	64.58	0.00e+00	699.00
IUUC-Tni-120340	Tetraodon nigroviridis	83.80	0.00e+00	640.00
IUUC-Tbe-127997	Tupaia belangeri	71.40	0.00e+00	1060.00
IUUC-Ttr-129311	Tursiops truncatus	83.54	0.00e+00	1361.00
IUUC-Vpa-130145	Vicugna pacos	87.92	0.00e+00	1377.00
IUUC-Xtr-132496	Xenopus tropicalis	83.38	0.00e+00	662.00
IUUC-Xma-133610	Xiphophorus maculatus	84.75	0.00e+00	643.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence