iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-07	32.4	427	460

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 9    laf............sd.tllvsGsdDgtikvWD 29
           l++            s  +ll++G  Dgt++ WD
   Q: 427  LSWpitggrnlaqepSQrGLLLTGHEDGTVRFWD 460
           55666666666666444689************** PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MMKFRFRRQG ADPQREKLKQ ELFAFHKTVE HGFPNQPSAL AFDPELRIMA IGTRSGAVKI 60
YGAPGVEFTG LHRDAATVTQ MHFLPGQGRL LTLLDDSSLH LWEIIQRNGC AHLEEGLSFH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGGACCG GCGGGGCCGG GCGCATCCCG CGGCGGTGGC GGAGGCGGGC GCAAGATGAT 60
GAAGTTTCGG TTCCGGCGGC AGGGCGCAGA CCCGCAGCGC GAGAAGCTCA AGCAGGAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013905--Lgl_C_dom
IPR013577--LLGL2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2

Pfam

PF08596--Lgl_C
PF08366--LLGL

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0030864--C:cortical actin cytoskeleton
GO:0030866--P:cortical actin cytoskeleton organization
GO:0006461--P:protein complex assembly

KEGG

rno:54265

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001841	Ailuropoda melanoleuca	87.22	0.00e+00	1691.00
IUUC-Aca-005314	Anolis carolinensis	73.58	0.00e+00	1493.00
IUUC-Ame-011869	Astyanax mexicanus	67.60	0.00e+00	1418.00
IUUC-Bta-013086	Bos taurus	85.21	0.00e+00	1765.00
IUUC-Cja-019964	Callithrix jacchus	88.95	0.00e+00	1759.00
IUUC-Cfa-021081	Canis familiaris	89.14	0.00e+00	1809.00
IUUC-Cpo-022226	Cavia porcellus	88.20	0.00e+00	1654.00
IUUC-Csa-023680	Chlorocebus sabaeus	89.70	0.00e+00	1808.00
IUUC-Cin-025693	Ciona intestinalis	46.42	0.00e+00	728.00
IUUC-Csv-025981	Ciona savignyi	47.82	0.00e+00	835.00
IUUC-Dre-027684	Danio rerio	67.50	0.00e+00	1404.00
IUUC-Dor-030545	Dipodomys ordii	89.89	0.00e+00	1820.00
IUUC-Ete-033043	Echinops telfairi	83.53	0.00e+00	718.00
IUUC-Eca-034305	Equus caballus	87.90	0.00e+00	1744.00
IUUC-Fca-035636	Felis catus	88.01	0.00e+00	1727.00
IUUC-Fal-037109	Ficedula albicollis	72.71	0.00e+00	1508.00
IUUC-Gmo-039657	Gadus morhua	66.45	0.00e+00	965.00
IUUC-Gga-040497	Gallus gallus	72.20	0.00e+00	1536.00
IUUC-Gac-041546	Gasterosteus aculeatus	63.69	0.00e+00	1321.00
IUUC-Ggo-045291	Gorilla gorilla	89.33	0.00e+00	1781.00
IUUC-Hsa-046004	Homo sapiens	89.14	0.00e+00	1774.00
IUUC-Itr-048031	Ictidomys tridecemlineatus	88.58	0.00e+00	1751.00
IUUC-Lch-049832	Latimeria chalumnae	65.78	0.00e+00	1300.00
IUUC-Loc-052641	Lepisosteus oculatus	68.57	0.00e+00	1455.00
IUUC-Laf-054218	Loxodonta africana	87.22	0.00e+00	1647.00
IUUC-Mcc-055013	Macaca mulatta	89.51	0.00e+00	1802.00
IUUC-Mga-060026	Meleagris gallopavo	67.75	0.00e+00	1370.00
IUUC-Mdo-062135	Monodelphis domestica	75.70	0.00e+00	1587.00
IUUC-Mmu-063168	Mus musculus	95.78	0.00e+00	1936.00
IUUC-Mpu-066685	Mustela putorius furo	89.16	0.00e+00	1743.00
IUUC-Mlu-067389	Myotis lucifugus	87.45	0.00e+00	1804.00
IUUC-Opr-070896	Ochotona princeps	85.23	0.00e+00	1710.00
IUUC-Ont-071498	Oreochromis niloticus	64.11	0.00e+00	1261.00
IUUC-Oan-073365	Ornithorhynchus anatinus	75.10	0.00e+00	1501.00
IUUC-Ocu-074237	Oryctolagus cuniculus	86.14	0.00e+00	1239.00
IUUC-Ola-086914	Oryzias latipes	61.20	0.00e+00	1271.00
IUUC-Oga-088401	Otolemur garnettii	89.21	0.00e+00	1756.00
IUUC-Oar-089232	Ovis aries	83.62	0.00e+00	1717.00
IUUC-Ptr-090647	Pan troglodytes	89.15	0.00e+00	1727.00
IUUC-Pan-092339	Papio anubis	89.61	0.00e+00	1803.00
IUUC-Psi-093016	Pelodiscus sinensis	65.78	0.00e+00	1218.00
IUUC-Pfo-096941	Poecilia formosa	64.01	0.00e+00	1311.00
IUUC-Pab-098102	Pongo abelii	89.29	0.00e+00	1768.00
IUUC-Pva-102768	Pteropus vampyrus	87.45	0.00e+00	1840.00
IUUC-Sar-113145	Sorex araneus	86.05	0.00e+00	1064.00
IUUC-Tru-118539	Takifugu rubripes	67.21	0.00e+00	1269.00
IUUC-Tsy-119013	Tarsius syrichta	86.00	0.00e+00	911.00
IUUC-Ttr-128232	Tursiops truncatus	83.24	0.00e+00	1682.00
IUUC-Xtr-132060	Xenopus tropicalis	71.33	0.00e+00	1500.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence